633 Matching Annotations
  1. Oct 2021
  2. www.science.org www.science.org
    Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer
    1
    1. scibot 18 Oct 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1126/scitranslmed.abb3738

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    science.org/doi/abs/10.1126/scitranslmed.abb3738
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels
    1
    1. scibot 15 Oct 2021
      JAX stock #005557

      DOI: 10.1126/sciadv.abi7511

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC8494442/
  4. www.sciencedirect.com www.sciencedirect.com
    Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells
    1
    1. scibot 13 Oct 2021
      005557

      DOI: 10.1016/j.celrep.2021.109812

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    sciencedirect.com/science/article/pii/S2211124721012766
  5. Sep 2021
  6. www.sciencedirect.com www.sciencedirect.com
    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
    1
    1. scibot 23 Sep 2021
      Strain# 005557

      DOI: 10.1016/j.molcel.2021.08.034

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    sciencedirect.com/science/article/pii/S1097276521007140
  7. www.sciencedirect.com www.sciencedirect.com
    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
    1
    1. scibot 21 Sep 2021
      Stock# 005557

      DOI: 10.1016/j.celrep.2021.109689

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    sciencedirect.com/science/article/pii/S2211124721011360
  8. www.sciencedirect.com www.sciencedirect.com
    Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer
    1
    1. scibot 15 Sep 2021
      005,557

      DOI: 10.1016/j.chembiol.2021.08.011

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    sciencedirect.com/science/article/pii/S2451945621004001
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    Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
    1
    1. scibot 15 Sep 2021
      JAX:005557

      DOI: 10.1016/j.stem.2021.08.013

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    sciencedirect.com/science/article/pii/S1934590921003507
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    Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor
    1
    1. scibot 14 Sep 2021
      005557

      DOI: 10.1016/j.ccell.2021.08.009

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    sciencedirect.com/science/article/pii/S1535610821004499
  11. Aug 2021
  12. www.sciencedirect.com www.sciencedirect.com
    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
    1
    1. scibot 25 Aug 2021
      JAX:005557

      DOI: 10.1016/j.celrep.2021.109568

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    sciencedirect.com/science/article/pii/S2211124721010020
  13. www.sciencedirect.com www.sciencedirect.com
    Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
    1
    1. scibot 18 Aug 2021
      Stock No: 005557

      DOI: 10.1016/j.celrep.2021.109538

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    sciencedirect.com/science/article/pii/S2211124721009724
  14. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
    1
    1. scibot 16 Aug 2021
      JAX:005557

      DOI: 10.1016/j.ccell.2021.07.006

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    sciencedirect.com/science/article/pii/S1535610821003834
  15. www.sciencedirect.com www.sciencedirect.com
    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
    1
    1. scibot 16 Aug 2021
      JAX:005557

      DOI: 10.1016/j.cell.2021.07.020

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    sciencedirect.com/science/article/pii/S0092867421008795
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
    1
    1. scibot 15 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-20-0331

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    ncbi.nlm.nih.gov/pmc/articles/PMC8110214/
  17. www.sciencedirect.com www.sciencedirect.com
    Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.06.003

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    sciencedirect.com/science/article/pii/S1535610819302946
  18. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
    1
    1. scibot 11 Aug 2021
      JAX:005557

      DOI: 10.1016/j.stem.2016.12.001

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    sciencedirect.com/science/article/pii/S193459091630457X
  19. www.sciencedirect.com www.sciencedirect.com
    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
    1
    1. scibot 07 Aug 2021
      Stock No: 005557

      DOI: 10.1016/j.molcel.2021.07.018

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      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S1097276521005876
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer
    1
    1. scibot 06 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.43024

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    ncbi.nlm.nih.gov/pmc/articles/PMC6597241/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft.
    1
    1. scibot 05 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1541-7786.MCR-20-0686

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7864867/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
    1
    1. scibot 05 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.70429

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8321552/
  23. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 04 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2018.11.006

      Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)

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    sciencedirect.com/science/article/pii/S1535610818305270
  24. www.sciencedirect.com www.sciencedirect.com
    TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate
    1
    1. scibot 04 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2021.07.003

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    sciencedirect.com/science/article/pii/S1934590921002885
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 04 Aug 2021
      JAX:005557

      DOI: 10.1016/j.stem.2016.12.001

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      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC5822422/
  26. www.sciencedirect.com www.sciencedirect.com
    The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
    1
    1. scibot 03 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2017.11.025

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    sciencedirect.com/science/article/pii/S1097276517308845
  27. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
    1
    1. scibot 03 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2018.06.012

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    sciencedirect.com/science/article/pii/S1535610818302691
  28. www.sciencedirect.com www.sciencedirect.com
    The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2019.05.069

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      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S2211124719306989
  29. Jul 2021
  30. www.sciencedirect.com www.sciencedirect.com
    A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
    1
    1. scibot 31 Jul 2021
      Mouse: NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG)

      DOI: 10.1016/j.ccell.2019.11.001

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610819305215
  31. www.sciencedirect.com www.sciencedirect.com
    TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2021.07.003

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    sciencedirect.com/science/article/pii/S1535610821003809
  32. www.sciencedirect.com www.sciencedirect.com
    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.01.006

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:005557 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819300406
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    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.02.003

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:005557 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819300984
  34. www.sciencedirect.com www.sciencedirect.com
    Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body
    1
    1. scibot 30 Jul 2021
      Jackson Laboratory005557

      DOI: 10.1016/j.cell.2019.11.013

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S0092867419312693
  35. www.sciencedirect.com www.sciencedirect.com
    N6-methyladenine DNA Modification in Glioblastoma
    1
    1. scibot 30 Jul 2021
      JAX:005557

      DOI: 10.1016/j.cell.2018.10.006

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S009286741831314X
  36. www.sciencedirect.com www.sciencedirect.com
    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2018.09.051

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      RRIDCUR:Validated RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S0092867418312637
  37. www.sciencedirect.com www.sciencedirect.com
    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.devcel.2018.10.001

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      RRIDCUR:Validated RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S1534580718308220
  38. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2018.08.018

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    sciencedirect.com/science/article/pii/S1934590918304363
  39. www.sciencedirect.com www.sciencedirect.com
    Metabolic Rewiring in Response to Biguanides Is Mediated by mROS/HIF-1a in Malignant Lymphocytes
    1
    1. scibot 29 Jul 2021
      Jackson LaboratoryStock No:#005557

      DOI: 10.1016/j.celrep.2019.11.007

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S2211124719314780
  40. www.sciencedirect.com www.sciencedirect.com
    Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
    1
    1. scibot 29 Jul 2021
      The Jackson LaboratoryCat#005557

      DOI: 10.1016/j.stem.2019.10.005

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S1934590919304266
  41. www.sciencedirect.com www.sciencedirect.com
    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
    1
    1. scibot 29 Jul 2021
      The Jackson LaboratoryStock# 005557

      DOI: 10.1016/j.celrep.2019.08.076

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      RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S2211124719311313
  42. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
    1
    1. scibot 29 Jul 2021
      JAX : 005557

      DOI: 10.1016/j.ccell.2019.08.005

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    Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer
    1
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      The Jackson LaboratoryStock #: 005557

      DOI: 10.1016/j.stem.2019.08.004

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    LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL
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      The Jackson LaboratoryCat# 005557

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    Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
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      005557

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    An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
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      Jackson laboratoryCat#5557

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    Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
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      RRID: IMSR_JAX:005557

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    Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
    1
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      Mouse: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG)

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    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
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      Mouse strain: NSG; NOD.Cg-PrkdcscidIL2rgtm1Wjl/ Szj

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  50. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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    Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying hemizygous 208insC mutations in the IDS gene
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      JAX No. 005557

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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection
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      005557

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    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
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      005557

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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Myogenic Double-Reporter Human Pluripotent Stem Cell Line Allows Prospective Isolation of Skeletal Muscle Progenitors
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      005557

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    IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation
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      005557

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    Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
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      005557

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    Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
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      005557

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    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
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      005557

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      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2018.07.009

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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct skeletal stem cell types orchestrate long bone skeletogenesis
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      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.66063

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    Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis
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      RRID:IMSR_JAX:005557

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    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
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      RRID:IMSR_JAX005557

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    Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells
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    A universal gene correction approach for FKRP-associated dystroglycanopathies to enable autologous cell therapy
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      005557

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    Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides
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      Cat # 005557

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  68. elifesciences.org elifesciences.org
    Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
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  69. Jun 2021
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    Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
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      RRID:IMSR_JAX:005557

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    Metabolic imaging with hyperpolarized [1-13C] pyruvate in patient-derived preclinical mouse models of breast cancer
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    High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids - Nicholas Choo, Susanne Ramm, Jennii Luu, Jean M. Winter, Luke A. Selth, Amy R. Dwyer, Mark Frydenberg, Jeremy Grummet, Shahneen Sandhu, Theresa E. Hickey, Wayne D. Tilley, Renea A. Taylor, Gail P. Risbridger, Mitchell G. Lawrence, Kaylene J. Simpson, 2021
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    The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation
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    Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree
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      Stock 005557

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    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
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  76. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G>A in the ACVR1 gene
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      JAX No. 005557

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  77. May 2021
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    N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
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    Charting human development using a multi-endodermal organ atlas and organoid models
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      strain no. 0005557

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    Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility
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    Dynamic BH3 profiling method for rapid identification of active therapy in BH3 mimetics resistant xenograft mouse models
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      005557

      DOI: 10.1016/j.xpro.2021.100461

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  82. www.sciencedirect.com www.sciencedirect.com
    Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation
    1
    1. scibot 12 May 2021
      JAX 005557

      DOI: 10.1016/j.devcel.2021.02.025

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  83. www.sciencedirect.com www.sciencedirect.com
    Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.12.017

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    sciencedirect.com/science/article/pii/S1934590920306019
  84. www.sciencedirect.com www.sciencedirect.com
    UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.12.002

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  85. www.sciencedirect.com www.sciencedirect.com
    Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras
    1
    1. scibot 09 May 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.11.019

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    sciencedirect.com/science/article/pii/S193459092030583X
  86. www.sciencedirect.com www.sciencedirect.com
    LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis
    1
    1. scibot 09 May 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.06.017

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  87. www.sciencedirect.com www.sciencedirect.com
    Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.07.003

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  88. www.cell.com www.cell.com
    The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
    1
    1. scibot 06 May 2021
      JAX:005557

      DOI: 10.1016/j.isci.2021.102435

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    cell.com/iscience/abstract/S2589-0042(21)00403-X
  89. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.devcel.2020.09.021

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    Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
    1
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      Jax Stock# 005557

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    sciencedirect.com/science/article/pii/S193459092100165X
  91. www.sciencedirect.com www.sciencedirect.com
    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
    1
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      Cat# 005557

      DOI: 10.1016/j.cmet.2021.02.001

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    sciencedirect.com/science/article/pii/S1550413121000577
  92. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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      JAX:005557

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    sciencedirect.com/science/article/pii/S1550413121001108
  93. Apr 2021
  94. www.sciencedirect.com www.sciencedirect.com
    Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells
    1
    1. scibot 30 Apr 2021
      Stock#005557

      DOI: 10.1016/j.cmet.2020.10.025

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  95. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
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    1. scibot 29 Apr 2021
      005557

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  96. www.sciencedirect.com www.sciencedirect.com
    Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance
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    1. scibot 29 Apr 2021
      005557

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  97. www.sciencedirect.com www.sciencedirect.com
    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
    1
    1. scibot 29 Apr 2021
      Stock No: 005557

      DOI: 10.1016/j.cmet.2020.07.008

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  98. www.sciencedirect.com www.sciencedirect.com
    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
    1
    1. scibot 29 Apr 2021
      JAX- 005557

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  99. www.sciencedirect.com www.sciencedirect.com
    Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
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    1. scibot 29 Apr 2021
      Stock No: 005557

      DOI: 10.1016/j.immuni.2021.04.002

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    sciencedirect.com/science/article/pii/S1074761321001394
  100. www.sciencedirect.com www.sciencedirect.com
    An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity
    1
    1. scibot 28 Apr 2021
      005557

      DOI: 10.1016/j.chembiol.2020.11.012

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  101. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      Cat#005557

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  102. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
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      005557

      DOI: 10.1016/j.cell.2020.07.009

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    sciencedirect.com/science/article/pii/S0092867420308746
  103. www.sciencedirect.com www.sciencedirect.com
    Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
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    1. scibot 24 Apr 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2021.01.022

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    sciencedirect.com/science/article/pii/S0092867421000659
  104. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.08.022

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    sciencedirect.com/science/article/pii/S0092867420310138
  105. rupress.org rupress.org
    Human KIT+ myeloid cells facilitate visceral metastasis by melanoma
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      JAX:005557

      DOI: 10.1084/jem.20182163

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    rupress.org/jem/article/218/6/e20182163/211995/Human-KIT-myeloid-cells-facilitate-visceral
  106. www.sciencedirect.com www.sciencedirect.com
    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
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      005557

      DOI: 10.1016/j.ccell.2021.02.006

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  107. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
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    1. scibot 22 Apr 2021
      Ref 5557

      DOI: 10.1016/j.ccell.2021.02.003

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  108. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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      005557

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  109. www.sciencedirect.com www.sciencedirect.com
    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
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      JAX:005557

      DOI: 10.1016/j.ccell.2020.12.023

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    Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
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      005557

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    sciencedirect.com/science/article/pii/S1535610820303160
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    Mass spectrometry analysis of circulating breast cancer cells from a Xenograft mouse model
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      Cat# 5557

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  112. www.sciencedirect.com www.sciencedirect.com
    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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      RRID:IMSR_JAX:005557

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  113. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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      Strain# 005557

      DOI: 10.1016/j.ccell.2020.04.014

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    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
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    Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
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  116. Mar 2021
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/2643-3230.BCD-20-0161

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  118. Feb 2021
  119. www.nature.com www.nature.com
    Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
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      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.61980

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  121. www.cell.com www.cell.com
    Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2021.01.004

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    Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
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  123. insight.jci.org insight.jci.org
    Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells
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    A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
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      DOI: 10.1016/j.ebiom.2021.103220

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    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.11.012

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  126. Jan 2021
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    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
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      Cat# 005557

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    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
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      NSG mice

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  129. Dec 2020
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    Tracking HIV Rebound following Latency Reversal Using Barcoded HIV
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    Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation
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    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
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      NOD-scidIL2Rgammanull

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    Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis
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      RRID:IMSR_JAX:005557

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    The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2020.108474

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    Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo
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      RRID:IMSR_JAX:005557

      DOI: 10.1007/s00262-020-02780-9

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  136. Nov 2020
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    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2020.100131

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  138. Oct 2020
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    Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis
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      NOD-scid IL2Rgammanull (NSG) Mouse

      DOI: 10.1016/j.xpro.2020.100124

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  140. Sep 2020
  141. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction
    1
    1. scibot 26 Sep 2020
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice

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    Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.05.039

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    Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.02.002

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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.56913

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    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.08.016

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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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      RRID:IMSR_JAX:005557

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    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
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      RRID:IMSR_JAX:005557

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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.02.001

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  149. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.02.019

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    LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
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      RRID:IMSR_JAX:005557

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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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      RRID:IMSR_JAX:005557

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  152. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches
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      JAX:005557

      DOI: 10.1158/0008-5472.CAN-19-2961

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    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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      RRID:IMSR_JAX:005557

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
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      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.53381

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    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
    1
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      RRID:IMSR_JAX:005557

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    Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
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      RRID:IMSR_JAX:005557

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    Axon-like protrusions promote small cell lung cancer migration and metastasis
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      RRID:IMSR_JAX:005557

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    Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia
    1
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      RRID:IMSR_JAX:005557

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    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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      RRID:IMSR_JAX:005557

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    Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis
    1
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      Mouse: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

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    Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics
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      Nod-Scid-Gamma

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  162. www.nature.com www.nature.com
    Rapid generation of Col7a1 −/− mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells
    1
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      NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ

      DOI: 10.1038/labinvest.2017.85

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    nature.com/articles/labinvest201785
  163. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling
    1
    1. scibot 04 Sep 2020
      C57BL/6

      DOI: 10.1172/JCI129061

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    pmc.ncbi.nlm.nih.gov/articles/PMC6934217/
  164. www.nature.com www.nature.com
    The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer
    1
    1. scibot 04 Sep 2020
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ NSG

      DOI: 10.1038/s41388-020-1196-5

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    nature.com/articles/s41388-020-1196-5
  165. www.nature.com www.nature.com
    Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice
    1
    1. scibot 04 Sep 2020
      Jackson Laboratory (strain #005557

      DOI: 10.1038/s41598-019-55729-z

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    nature.com/articles/s41598-019-55729-z
  166. www.nature.com www.nature.com
    Isolation of satellite cells and transplantation into mice for lineage tracing in muscle
    1
    1. scibot 04 Sep 2020
      JAX, cat no. 005557

      DOI: 10.1038/s41596-019-0278-8

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    nature.com/articles/s41596-019-0278-8
  167. www.sciencedirect.com www.sciencedirect.com
    Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
    1
    1. scibot 03 Sep 2020
      Jackson Laboratory005557

      DOI: 10.1016/j.celrep.2020.107688

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    sciencedirect.com/science/article/pii/S2211124720306410
  168. www.sciencedirect.com www.sciencedirect.com
    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
    1
    1. scibot 03 Sep 2020
      The Jackson LaboratoryCat#005557

      DOI: 10.1016/j.cell.2020.03.051

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    sciencedirect.com/science/article/pii/S0092867420303445
  169. www.sciencedirect.com www.sciencedirect.com
    MYC Controls the Epstein-Barr Virus Lytic Switch
    1
    1. scibot 03 Sep 2020
      The Jackson Laboratory005557

      DOI: 10.1016/j.molcel.2020.03.025

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    sciencedirect.com/science/article/pii/S1097276520301933
  170. www.sciencedirect.com www.sciencedirect.com
    ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase
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      The Jackson Laboratory005557

      DOI: 10.1016/j.cmet.2020.03.008

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    sciencedirect.com/science/article/pii/S1550413120301236
  171. www.sciencedirect.com www.sciencedirect.com
    Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
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    1. scibot 03 Sep 2020
      The Jackson LaboratoryCat# 005557

      DOI: 10.1016/j.stem.2020.02.008

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    sciencedirect.com/science/article/pii/S1934590920300618
  172. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation
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      The Jackson Laboratory005557

      DOI: 10.1016/j.celrep.2020.02.080

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    sciencedirect.com/science/article/pii/S2211124720302540
  173. www.sciencedirect.com www.sciencedirect.com
    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
    1
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      Jackosn LabsStock No: 005557

      DOI: 10.1016/j.ccell.2020.01.011

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    sciencedirect.com/science/article/pii/S1535610820300507
  174. www.sciencedirect.com www.sciencedirect.com
    Comparison of Human Antral Follicles of Xenograft versus Ovarian Origin Reveals Disparate Molecular Signatures
    1
    1. scibot 03 Sep 2020
      female NSG

      DOI: 10.1016/j.celrep.2020.108027

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    sciencedirect.com/science/article/pii/S2211124720310123
  175. www.sciencedirect.com www.sciencedirect.com
    Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity
    1
    1. scibot 03 Sep 2020
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG™)

      DOI: 10.1016/j.celrep.2020.107905

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    sciencedirect.com/science/article/pii/S221112472030886X
  176. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Protocol for Cloning Epithelial Stem Cell Variants from Human Lung
    1
    1. scibot 03 Sep 2020
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

      DOI: 10.1016/j.xpro.2020.100063

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  177. Aug 2020
  178. www.sciencedirect.com www.sciencedirect.com
    Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus
    1
    1. scibot 21 Aug 2020
      The Jackson LaboratoryStock No: 005557

      DOI: 10.1016/j.xcrm.2020.100033

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    sciencedirect.com/science/article/pii/S2666379120300458
  179. www.sciencedirect.com www.sciencedirect.com
    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
    1
    1. scibot 15 Aug 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.12.003

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    sciencedirect.com/science/article/pii/S1535610819305732
  180. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exosome/Microvesicle Content is Altered in LRRK2 Mutant iPSC‐derived Neural Cells
    1
    1. scibot 15 Aug 2020
      The Jackson Laboratory, Stock# 005557

      DOI: 10.1002/cne.24819

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    onlinelibrary.wiley.com/doi/10.1002/cne.24819
  181. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 14 Aug 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  182. Jan 2020
  183. www.sciencedirect.com www.sciencedirect.com
    Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2019.06.001

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    sciencedirect.com/science/article/pii/S1097276519304344
  184. cancerres.aacrjournals.org cancerres.aacrjournals.org
    HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-18-1377

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    cancerres.aacrjournals.org/content/78/21/6196
  185. www.sciencedirect.com www.sciencedirect.com
    CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2019.11.008

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    sciencedirect.com/science/article/pii/S2211124719314792
  186. www.sciencedirect.com www.sciencedirect.com
    Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2019.06.009

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    sciencedirect.com/science/article/pii/S1934590919302735
  187. www.sciencedirect.com www.sciencedirect.com
    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2019.08.105

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    sciencedirect.com/science/article/pii/S2211124719311672
  188. www.sciencedirect.com www.sciencedirect.com
    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2019.06.005

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    sciencedirect.com/science/article/pii/S0092867419306336
  189. www.sciencedirect.com www.sciencedirect.com
    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.09.005

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    sciencedirect.com/science/article/pii/S1535610819304258
  190. www.sciencedirect.com www.sciencedirect.com
    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2019.08.032

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    sciencedirect.com/science/article/pii/S0092867419309511
  191. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      JAX:005557

      DOI: 10.1016/j.stem.2018.12.003

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    sciencedirect.com/science/article/pii/S1934590918305939
  192. www.sciencedirect.com www.sciencedirect.com
    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.01.006

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  193. www.sciencedirect.com www.sciencedirect.com
    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.02.003

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    sciencedirect.com/science/article/pii/S1535610819300984
  194. www.sciencedirect.com www.sciencedirect.com
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      RRID:IMSR_JAX005557

      DOI: 10.1016/j.celrep.2019.03.085

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    sciencedirect.com/science/article/pii/S2211124719304243
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2018.12.090

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    sciencedirect.com/science/article/pii/S2211124718320503
  196. www.sciencedirect.com www.sciencedirect.com
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cels.2018.10.005

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    sciencedirect.com/science/article/pii/S2405471218303958
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41408-018-0165-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
  198. www.sciencedirect.com www.sciencedirect.com
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      JAX:005557

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    sciencedirect.com/science/article/pii/S1934590918306015
  199. Nov 2018
  200. www.sciencedirect.com www.sciencedirect.com
    Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
    1
    1. scibot 05 Nov 2018
      005557

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  201. www.sciencedirect.com www.sciencedirect.com
    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
    1
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      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627318308481
  202. www.sciencedirect.com www.sciencedirect.com
    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413118306284
  203. www.sciencedirect.com www.sciencedirect.com
    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418311796
  204. www.sciencedirect.com www.sciencedirect.com
    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610818303763
  205. www.sciencedirect.com www.sciencedirect.com
    ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276518306890
  206. www.sciencedirect.com www.sciencedirect.com
    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590918303941
  207. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S2211124718313494
  208. www.sciencedirect.com www.sciencedirect.com
    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418310298
  209. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610818303593
  210. www.sciencedirect.com www.sciencedirect.com
    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590918303874
  211. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413118305096
  212. www.sciencedirect.com www.sciencedirect.com
    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610818303180
  213. www.sciencedirect.com www.sciencedirect.com
    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867418302885
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC6134179/
  215. www.sciencedirect.com www.sciencedirect.com
    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867418309097
  216. www.sciencedirect.com www.sciencedirect.com
    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590918302844
  217. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
    1
    1. scibot 05 Nov 2018
      JAX:005557

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      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557
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    sciencedirect.com/science/article/pii/S1934590917305118