935 Matching Annotations
  1. May 2021
  2. rupress.org rupress.org
    Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
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    rupress.org/jem/article/218/5/e20200924/211914/Mitochondrial-metabolism-supports-resistance-to
  3. academic.oup.com academic.oup.com
    NC1-peptide from collagen α3 (IV) chains in the basement membrane of testes regulates spermatogenesis via p-FAK-Y407
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    academic.oup.com/endo/article/161/10/bqaa133/5881724
  4. academic.oup.com academic.oup.com
    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
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    academic.oup.com/jcem/article/106/3/718/6009067
  5. mcr.aacrjournals.org mcr.aacrjournals.org
    Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM
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    mcr.aacrjournals.org/content/19/1/150
  6. academic.oup.com academic.oup.com
    Removal of epididymal visceral adipose tissue prevents obesity-induced multi-organ insulin resistance in male mice
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    academic.oup.com/jes/article/5/5/bvab024/6145120
  7. www.sciencedirect.com www.sciencedirect.com
    Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains
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    sciencedirect.com/science/article/pii/S2451945621002063
  8. www.sciencedirect.com www.sciencedirect.com
    Hdac9 inhibits medial artery calcification through down-regulation of Osterix
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    sciencedirect.com/science/article/pii/S1537189120300392
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    The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction
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    sciencedirect.com/science/article/pii/S0041008X20302593
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    Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
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    sciencedirect.com/science/article/pii/S1934590920302721
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    Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
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    sciencedirect.com/science/article/pii/S1934590920301442
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    Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex
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    sciencedirect.com/science/article/pii/S0896627320307583
  13. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
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    sciencedirect.com/science/article/pii/S1097276520306870
  14. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
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    sciencedirect.com/science/article/pii/S1097276520305190
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    Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases
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    sciencedirect.com/science/article/pii/S1097276520304202
  16. www.sciencedirect.com www.sciencedirect.com
    Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation
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    sciencedirect.com/science/article/pii/S1097276520302756
  17. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    sciencedirect.com/science/article/pii/S1074761320302715
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    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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    sciencedirect.com/science/article/pii/S1534580720305888
  19. www.sciencedirect.com www.sciencedirect.com
    HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
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    sciencedirect.com/science/article/pii/S1934590921000588
  20. www.cell.com www.cell.com
    LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome
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    cell.com/cell/fulltext/S0092-8674(21)00436-0
  21. Apr 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
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    sciencedirect.com/science/article/pii/S1550413120306562
  23. www.sciencedirect.com www.sciencedirect.com
    Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
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    sciencedirect.com/science/article/pii/S1535610821001707
  24. www.sciencedirect.com www.sciencedirect.com
    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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    sciencedirect.com/science/article/pii/S1550413120304769
  25. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S1550413120305519
  26. www.sciencedirect.com www.sciencedirect.com
    Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty
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    sciencedirect.com/science/article/pii/S1550413120305349
  27. www.sciencedirect.com www.sciencedirect.com
    Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
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    sciencedirect.com/science/article/pii/S1550413120304241
  28. www.sciencedirect.com www.sciencedirect.com
    Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells
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    sciencedirect.com/science/article/pii/S2451945620303408
  29. www.sciencedirect.com www.sciencedirect.com
    An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping
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    sciencedirect.com/science/article/pii/S0092867420313878
  30. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610820305419
  31. www.sciencedirect.com www.sciencedirect.com
    Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
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    sciencedirect.com/science/article/pii/S1097276521002641
  32. www.sciencedirect.com www.sciencedirect.com
    Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X
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    sciencedirect.com/science/article/pii/S0166432820306549
  33. www.sciencedirect.com www.sciencedirect.com
    Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth
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    sciencedirect.com/science/article/pii/S2451945621000490
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC8027073/
  35. Mar 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7985201/
  37. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Maternal high‐salt diet during pregnancy impairs synaptic plasticity and memory in offspring
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001890R
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN dephosphorylates Abi1 to promote epithelial morphogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7480098/
  39. www.sciencedirect.com www.sciencedirect.com
    Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer
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    sciencedirect.com/science/article/pii/S109727652100054X
  40. academic.oup.com academic.oup.com
    CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †
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    academic.oup.com/biolreprod/article/104/2/468/5952668
  41. www.sciencedirect.com www.sciencedirect.com
    Autophagy blockade limits HER2+ breast cancer tumorigenesis by perturbing HER2 trafficking and promoting release via small extracellular vesicles
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    sciencedirect.com/science/article/pii/S1534580720310224
  42. Feb 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Long-term kappa-carrageenan consumption leads to moderate metabolic disorder by blocking insulin binding
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    sciencedirect.com/science/article/pii/S1043661820317254
  44. academic.oup.com academic.oup.com
    Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring
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    academic.oup.com/endo/article/162/1/bqaa214/5992137
  45. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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    sciencedirect.com/science/article/pii/S1550413120306665
  46. www.sciencedirect.com www.sciencedirect.com
    Alternative signaling pathways from IGF1 or Insulin to Akt activation and Foxo1 nuclear efflux in adult skeletal muscle fibers
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    sciencedirect.com/science/article/pii/S0021925817503622
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC7700684/
  48. journals.sagepub.com journals.sagepub.com
    ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021
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    journals.sagepub.com/doi/abs/10.1177/0271678X20984976
  49. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15059
  50. www.cell.com www.cell.com
    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
  51. www.sciencedirect.com www.sciencedirect.com
    Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling
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    sciencedirect.com/science/article/pii/S2211124721000784
  52. www.sciencedirect.com www.sciencedirect.com
    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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    sciencedirect.com/science/article/pii/S2211124721000929
  53. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14985
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA RP6‐65G23.1 accelerates proliferation and inhibits apoptosis via p‐ERK1/2/p‐AKT signaling pathway on keratinocytes
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    onlinelibrary.wiley.com/doi/10.1002/jcb.29685
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive pharmacogenomic characterization of gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7029441/
  56. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  57. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP278933
  58. academic.oup.com academic.oup.com
    IGFBP-1 in cardiometabolic pathophysiology – insights from loss-of-function and gain-of-function studies in male mice
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    academic.oup.com/jes/article/4/1/bvz006/5612295
  59. www.fasebj.org www.fasebj.org
    Cdc42 is involved in NC1 peptide–regulated BTB dynamics through actin and microtubule cytoskeletal reorganization
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    fasebj.org/doi/abs/10.1096/fj.201900991R
  60. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    sciencedirect.com/science/article/pii/S2211124721000577
  61. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy
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    sciencedirect.com/science/article/pii/S2211124721000449
  62. Jan 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution
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    sciencedirect.com/science/article/pii/S2211124720316132
  64. www.sciencedirect.com www.sciencedirect.com
    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
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    sciencedirect.com/science/article/pii/S221112472031648X
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
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    ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
  66. www.sciencedirect.com www.sciencedirect.com
    Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3
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    sciencedirect.com/science/article/pii/S2211124720315655
  67. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
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    sciencedirect.com/science/article/pii/S2211124720315837
  68. elifesciences.org elifesciences.org
    Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division
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    elifesciences.org/articles/63835
  69. Dec 2020
  70. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14672
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
  72. www.sciencedirect.com www.sciencedirect.com
    Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling
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    sciencedirect.com/science/article/pii/S2211124720314169
  73. www.sciencedirect.com www.sciencedirect.com
    miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling
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    sciencedirect.com/science/article/pii/S221112472031425X
  74. Nov 2020
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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    ncbi.nlm.nih.gov/pmc/articles/PMC7661039/
  76. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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    pubmed.ncbi.nlm.nih.gov/33167355/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cdc42 is involved in NC1 peptide–regulated BTB dynamics through actin and microtubule cytoskeletal reorganization
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6894087/
  78. Oct 2020
  79. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy
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    pubmed.ncbi.nlm.nih.gov/33205074/
  80. www.jneurosci.org www.jneurosci.org
    Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR
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    jneurosci.org/content/40/42/8174
  81. academic.oup.com academic.oup.com
    Mechanisms by which membrane and nuclear ER alpha inhibit adipogenesis in cells isolated from female mice
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    academic.oup.com/endo/article/161/11/bqaa175/5911730
  82. www.mdpi.com www.mdpi.com
    Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice
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    mdpi.com/2227-9059/8/10/420
  83. www.cell.com www.cell.com
    Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
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    cell.com/developmental-cell/abstract/S1534-5807(20)30420-2
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7542386/
  85. www.sciencedirect.com www.sciencedirect.com
    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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    sciencedirect.com/science/article/pii/S2211124720312122
  86. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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    sciencedirect.com/science/article/pii/S2211124720312171
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC7506102/
  88. Sep 2020
  89. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas
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    pubmed.ncbi.nlm.nih.gov/32997991/
  90. www.nature.com www.nature.com
    Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy
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    nature.com/articles/s41419-020-2615-9
  91. www.sciencedirect.com www.sciencedirect.com
    Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice
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    sciencedirect.com/science/article/pii/S1550413120300139
  92. www.sciencedirect.com www.sciencedirect.com
    Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade
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    sciencedirect.com/science/article/pii/S2211124720307336
  93. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System
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    pubmed.ncbi.nlm.nih.gov/32668203/
  94. www.sciencedirect.com www.sciencedirect.com
    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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