1,345 Matching Annotations
  1. Jul 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice
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    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111062

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    sciencedirect.com/science/article/pii/S2211124722008609
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    A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
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    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111039

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    sciencedirect.com/science/article/pii/S2211124722008336
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    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
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    1. scibot 12 Jul 2022
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      DOI: 10.1016/j.devcel.2022.06.008

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    sciencedirect.com/science/article/pii/S1534580722004488
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins
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    1. scibot 12 Jul 2022
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      DOI: 10.3390/cancers14133129

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    ncbi.nlm.nih.gov/pmc/articles/PMC9265124/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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    1. scibot 12 Jul 2022
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      DOI: 10.3390/cancers14133152

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    ncbi.nlm.nih.gov/pmc/articles/PMC9264918/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    1. scibot 06 Jul 2022
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      DOI: 10.1158/0008-5472.CAN-21-1467

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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
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    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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    1. scibot 06 Jul 2022
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      DOI: 10.1158/0008-5472.CAN-20-4218

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    ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
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    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
    1
    1. scibot 06 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111031

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    sciencedirect.com/science/article/pii/S2211124722008257
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    The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis
    1
    1. scibot 02 Jul 2022
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      DOI: 10.1016/j.molcel.2022.06.008

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    sciencedirect.com/science/article/pii/S1097276522005445
  11. Jun 2022
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    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
    1
    1. scibot 30 Jun 2022
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      DOI: 10.1016/j.devcel.2022.06.003

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    sciencedirect.com/science/article/pii/S1534580722004129
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    A Novel Somatic Mutation of CACNA1H p.V1937M in Unilateral Primary Hyperaldosteronism
    1
    1. scibot 25 Jun 2022
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      DOI: 10.3389/fendo.2022.816476

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    ncbi.nlm.nih.gov/pmc/articles/PMC9218183/
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    The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity
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    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.isci.2022.104561

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    sciencedirect.com/science/article/pii/S2589004222008331
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    Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation
    1
    1. scibot 17 Jun 2022
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      DOI: 10.1038/s42255-021-00454-z

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    nature.com/articles/s42255-021-00454-z
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    Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110943

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    sciencedirect.com/science/article/pii/S2211124722007252
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    Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110939

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    sciencedirect.com/science/article/pii/S2211124722007215
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    Receptor editing constrains development of phosphatidyl choline-specific B cells in VH12-transgenic mice
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110899

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    sciencedirect.com/science/article/pii/S221112472200674X
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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110928

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    sciencedirect.com/science/article/pii/S2211124722007100
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    CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110853

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    sciencedirect.com/science/article/pii/S221112472200626X
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    PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine
    1
    1. scibot 08 Jun 2022
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      DOI: 10.1016/j.devcel.2022.05.007

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    sciencedirect.com/science/article/pii/S1534580722003495
  22. May 2022
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    Feedback from nuclear RNA on transcription promotes robust RNA concentration homeostasis in human cells
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    1. scibot 26 May 2022
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      DOI: 10.1016/j.cels.2022.04.005

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    sciencedirect.com/science/article/pii/S2405471222001703
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    Oxygen level regulates N-terminal translation elongation of selected proteins through deoxyhypusine hydroxylation
    1
    1. scibot 26 May 2022
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      DOI: 10.1016/j.celrep.2022.110855

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    sciencedirect.com/science/article/pii/S2211124722006283
  25. academic.oup.com academic.oup.com
    Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells
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    1. scibot 26 May 2022
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      DOI: 10.1093/humrep/deac112

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    academic.oup.com/humrep/advance-article/doi/10.1093/humrep/deac112/6590738
  26. link.springer.com link.springer.com
    The V2 receptor antagonist tolvaptan counteracts proliferation and invasivity in human cancer cells
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    1. scibot 26 May 2022
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      DOI: 10.1007/s40618-022-01807-5

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    link.springer.com/article/10.1007/s40618-022-01807-5
  27. pubs.acs.org pubs.acs.org
    Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance
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    1. scibot 24 May 2022
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      DOI: 10.1021/acs.biomac.2c00256

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    pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    1. scibot 21 May 2022
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      DOI: 10.1002/jbt.23099

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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  29. www.researchsquare.com www.researchsquare.com
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    1. scibot 20 May 2022
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      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/article/rs-2787982/v1
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    Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury
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    1. scibot 20 May 2022
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      DOI: 10.1016/j.isci.2022.104379

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    sciencedirect.com/science/article/pii/S2589004222006502
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    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
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    1. scibot 19 May 2022
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      DOI: 10.1016/j.isci.2022.104340

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    A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika
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    1. scibot 19 May 2022
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    sciencedirect.com/science/article/pii/S2211124722005873
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of ATF3 in Neuronal Differentiation and Development of Neuronal Networks in Opossum Postnatal Cortical Cultures
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    1. scibot 18 May 2022
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      DOI: 10.3390/ijms23094964

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    ncbi.nlm.nih.gov/pmc/articles/PMC9100162/
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    Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia
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      DOI: 10.1016/j.celrep.2022.110791

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    Protocol to induce and assess cGAS-STING pathway activation in vitro
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      DOI: 10.1016/j.xpro.2022.101384

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    sciencedirect.com/science/article/pii/S2666166722002647
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    Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
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      DOI: 10.1016/j.str.2022.04.006

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    sciencedirect.com/science/article/pii/S0969212622001332
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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      DOI: 10.1016/j.celrep.2022.110788

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    sciencedirect.com/science/article/pii/S2211124722005551
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function
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      DOI: 10.4103/1673-5374.336875

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    ncbi.nlm.nih.gov/pmc/articles/PMC9083168/
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    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  40. www.nature.com www.nature.com
    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
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      DOI: 10.1038/s41598-022-11116-9

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    nature.com/articles/s41598-022-11116-9
  41. Apr 2022
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    Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice
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      DOI: 10.1016/j.isci.2022.104241

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    sciencedirect.com/science/article/pii/S2589004222005119
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    Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice
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      DOI: 10.1016/j.xcrm.2022.100606

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    sciencedirect.com/science/article/pii/S2666379122001239
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    Generation of a human induced pluripotent stem cell line derived from a patient with dilated cardiomyopathy carrying LMNA nonsense mutation
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      DOI: 10.1016/j.scr.2022.102793

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    α2δ-1 Protein Promotes Synaptic Expression of Ca2+ Permeable–AMPA Receptors by Inhibiting GluA1/GluA2 Heteromeric Assembly in the Hypothalamus in Hypertension
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    Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity
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    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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    Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
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    Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells
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    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9
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    Cdc42 is required for male germline niche development in mice
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    The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A.Z binding in neurons
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    Circular RNA DLGAP4 ameliorates ischemic stroke outcomes by targeting miR-143 to regulate endothelial-mesenchymal transition associated with blood-brain barrier integrity
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