1,731 Matching Annotations
  1. Oct 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
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    ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
  3. www.science.org www.science.org
    A single-cell genomic atlas for maturation of the human cerebellum during early childhood
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    science.org/doi/10.1126/scitranslmed.ade1283
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    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
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    science.org/doi/10.1126/sciadv.abo3610
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10577912/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex-Dependent Synaptic Remodeling of the Somatosensory Cortex in Mice With Prenatal Methadone Exposure
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    ncbi.nlm.nih.gov/pmc/articles/PMC10569410/
  7. www.biorxiv.org www.biorxiv.org
    Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance
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    biorxiv.org/content/10.1101/2023.10.02.560611v1
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Loss of the parkinsonism-associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15962
  10. 52.53.155.43 52.53.155.43
    noad191-html.html
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    52.53.155.43/09af2d214e8e9e9be0d111b9b68aa6cfe94ec81e/noad191-html.html
  11. www.cell.com www.cell.com
    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
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    cell.com/iscience/abstract/S2589-0042(23)02087-4
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic–Ischemic Brain Injury in Neonatal Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10548811/
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    Impaired pre-synaptic plasticity and visual responses in Auxilin knockout mice
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    cell.com/iscience/abstract/S2589-0042(23)01919-3
  14. www.cell.com www.cell.com
    Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease
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    cell.com/cell-reports/abstract/S2211-1247(23)01082-3
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    Neuronal activity drives IGF2 expression from pericytes to form long-term memory
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    sciencedirect.com/science/article/pii/S0896627323006645
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of circadian disruption via dim light at night in C57BL6/J mice on recovery after spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516041/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PET imaging of microglia using PBR28suv determines therapeutic efficacy of autologous bone marrow mononuclear cells therapy in traumatic brain injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10522669/
  18. Sep 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10519710/
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    Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony
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    sciencedirect.com/science/article/pii/S2211124723011786
  21. 52.53.155.43 52.53.155.43
    Neuronal AR regulates glucose homeostasis and energy expenditure in lean female mice with androgen excess
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    52.53.155.43/3879cee9653b10d45813ef8c7ed9945ed72f559d/bqad141-html.html
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    A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1934590923002515
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Aging spinal cord microglia become phenotypically heterogeneous and preferentially target motor neurons and their synapses
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    onlinelibrary.wiley.com/doi/10.1002/glia.24470
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE)
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15956
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    One-step cell biomanufacturing platform: porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10503631/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10505217/
  27. link.springer.com link.springer.com
    Transcriptomics and translatomics identify a robust inflammatory gene signature in brain endothelial cells after ischemic stroke
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    link.springer.com/article/10.1186/s12974-023-02888-6
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Microglia contribute to cognitive decline in hypercholesterolemic LDLr−/− mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15952
  29. link.springer.com link.springer.com
    Effects of Ischemic Stroke on Interstitial Fluid Clearance in Mouse Brain: a Bead Study
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    link.springer.com/article/10.1007/s10571-023-01400-1
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/10.1002/glia.24461
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep–wake Disturbances in AD Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10476643/
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oligodendrocyte progenitor cells differentiation induction with MAPK/ERK inhibitor fails to support repair processes in the chronically demyelinated CNS
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    onlinelibrary.wiley.com/doi/10.1002/glia.24453
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal-derived extracellular vesicles enhance microglia-mediated synapse remodeling after cortical injury in aging Rhesus monkeys
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    ncbi.nlm.nih.gov/pmc/articles/PMC10475204/
  34. Aug 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits
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    sciencedirect.com/science/article/pii/S1535610823002507
  36. www.sciencedirect.com www.sciencedirect.com
    A comparative analysis of microglial inducible Cre lines
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    sciencedirect.com/science/article/pii/S2211124723010422
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trem2 Enhances Demyelination in the Csf1r+/− Mouse Model of Leukoencephalopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10452898/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cofilin overactivation improves hippocampus-dependent short-term memory
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    ncbi.nlm.nih.gov/pmc/articles/PMC10448394/
  39. www.sciencedirect.com www.sciencedirect.com
    Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease
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    sciencedirect.com/science/article/pii/S0896627323005482
  40. www.sciencedirect.com www.sciencedirect.com
    Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1550413123002735
  41. 52.53.155.43 52.53.155.43
    PIIS2211124723009671-html.html
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    Stress-induced Neuroinflammation of the Spinal Cord is Restrained by Cort113176 (Dazucorilant), A Specific Glucocorticoid Receptor Modulator
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    link.springer.com/article/10.1007/s12035-023-03554-x
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    Human microglia maturation is underpinned by specific gene regulatory networks
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    sciencedirect.com/science/article/pii/S1074761323003291
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues
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    ncbi.nlm.nih.gov/pmc/articles/PMC10369938/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process
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    ncbi.nlm.nih.gov/pmc/articles/PMC10413268/
  46. 52.53.155.43 52.53.155.43
    Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice
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    52.53.155.43/5178e3b5a29ba09ab2106f8993d42d5e0411ae62/awad264 (1)-html.html
  47. www.sciencedirect.com www.sciencedirect.com
    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
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    sciencedirect.com/science/article/pii/S2211124723009002
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prophylactic effect of chronic immunosuppression in a mouse model of CSF-1 receptor-related leukoencephalopathy
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    onlinelibrary.wiley.com/doi/10.1002/glia.24446
  49. Jul 2023
  50. 52.53.155.43 52.53.155.43
    Bowel dysmotility and enteric neuron degeneration in lysosomal storage disease mice is prevented by gene therapy
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    52.53.155.43/415af030e24e59a74141777602339d91f1c11723/2023.05.26.542524v1.full-html.html
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage
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    ncbi.nlm.nih.gov/pmc/articles/PMC10341986/
  52. www.sciencedirect.com www.sciencedirect.com
    AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice
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    sciencedirect.com/science/article/pii/S258900422301324X
  53. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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    sciencedirect.com/science/article/pii/S1535610823002179
  54. www.sciencedirect.com www.sciencedirect.com
    Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimer’s disease model mice
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    sciencedirect.com/science/article/pii/S2211124723007969
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson’s disease and neuronal damage through inhibition of microglia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328268/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Srgap2 suppression ameliorates retinal ganglion cell degeneration in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328280/
  57. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16157
  58. www.sciencedirect.com www.sciencedirect.com
    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
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    sciencedirect.com/science/article/pii/S0896627323004373
  59. www.sciencedirect.com www.sciencedirect.com
    Tet2 acts in the lateral habenula to regulate social preference in mice
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    sciencedirect.com/science/article/pii/S2211124723007064
  60. www.sciencedirect.com www.sciencedirect.com
    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
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    sciencedirect.com/science/article/pii/S1567576923009207
  61. www.sciencedirect.com www.sciencedirect.com
    Glutaminase 1 deficiency confined in forebrain neurons causes autism spectrum disorder-like behaviors
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    sciencedirect.com/science/article/pii/S2211124723007234
  62. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dysfunction and type I interferon signaling induce anxiodepressive-like behaviors in mice with neuropathic pain
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    sciencedirect.com/science/article/pii/S0014488623001553
  63. Jun 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial Galectin3 enhances endothelial metabolism and promotes pathological angiogenesis via Notch inhibition by competitively binding to Jag1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10300109/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced Neural Stem Cells Suppressed Neuroinflammation by Inhibiting the Microglial Pyroptotic Pathway in Intracerebral Hemorrhage Rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285565/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10286986/
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15876
  68. www.sciencedirect.com www.sciencedirect.com
    PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
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    sciencedirect.com/science/article/pii/S0896627323003951
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vasculature in the mouse colon and spatial relationships with the enteric nervous system, glia, and immune cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10272736/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC10275401/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal-Derived Extracellular Vesicles Enhance Microglia-mediated Synapse Remodeling after Cortical Injury in Rhesus Monkeys
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    ncbi.nlm.nih.gov/pmc/articles/PMC10246272/
  72. www.sciencedirect.com www.sciencedirect.com
    Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika Virus microcephaly
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    sciencedirect.com/science/article/pii/S2589004223009860
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    Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis
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    link.springer.com/article/10.1186/s12974-023-02822-w
  74. www.sciencedirect.com www.sciencedirect.com
    Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders
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    sciencedirect.com/science/article/pii/S221112472300640X
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterizing microglial senescence: Tau as a key player
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15866
  76. www.sciencedirect.com www.sciencedirect.com
    Short-chain fatty and carboxylic acid changes associated with fecal microbiota transplant communally influence microglial inflammation
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    sciencedirect.com/science/article/pii/S2405844023041154
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of microglia with PLX3397 attenuates MK-801-induced hyperactivity associated with regulating inflammation-related genes in the brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236309/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233787/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC10231773/
  80. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Gupte - The severity of SARS‐CoV‐2 infection in K18‐hACE2 mice is attenuated by a novel-html.html
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    52.53.155.43/12f6a77b5e5fc28a8f5f08da25763e967449ea83/British J Pharmacology - 2023 - Gupte - The severity of SARS-CoV-2 infection in K18-hACE2 mice is attenuated by a novel-html.html
  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Roflumilast protects against spatial memory impairments and exerts anti‐inflammatory effects after transient global cerebral ischemia
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    onlinelibrary.wiley.com/doi/10.1111/ejn.15089
  82. www.biorxiv.org www.biorxiv.org
    Model matters: Differential outcomes in traumatic optic neuropathy pathophysiology between blunt and blast-wave mediated head injuries
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    biorxiv.org/content/10.1101/2023.05.25.542261v1
  83. May 2023
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    microRNA-132 regulates gene expression programs involved in microglial homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10213004/
  85. www.sciencedirect.com www.sciencedirect.com
    In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury
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    sciencedirect.com/science/article/pii/S1534580723001922
  86. www.embopress.org www.embopress.org
    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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    embopress.org/doi/10.15252/embj.2022111790
  87. academic.oup.com academic.oup.com
    Metformin Improves Functional Outcomes, Activates Neural Precursor Cells, and Modulates Microglia in a Sex-Dependent Manner After Spinal Cord Injury
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    academic.oup.com/stcltm/advance-article/doi/10.1093/stcltm/szad030/7174953
  88. 52.53.155.43 52.53.155.43
    Towards discovering a novel family of peptides targeting neuroinflammatory states of brain microglia and astrocytes
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    52.53.155.43/f5f75eab55b9307d9956132a39d0556ca522d7fd/Journal of Neurochemistry - 2023 - Koss - Towards discovering a novel family of peptides targeting neuroinflammatory states-html.html
  89. www.sciencedirect.com www.sciencedirect.com
    Ovariectomy in mice primes hippocampal microglia to exacerbate behavioral sickness responses
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    sciencedirect.com/science/article/pii/S2666354623000522
  90. www.sciencedirect.com www.sciencedirect.com
    Opioids induce bidirectional synaptic plasticity in a brainstem pain centre in the rat
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    sciencedirect.com/science/article/pii/S1526590023004054
  91. www.biorxiv.org www.biorxiv.org
    Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state
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