1,697 Matching Annotations
  1. Mar 2024
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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    sciencedirect.com/science/article/pii/S0896627324000898
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    Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes
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    sciencedirect.com/science/article/pii/S2211124724001876
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    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
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    sciencedirect.com/science/article/pii/S2211124724001980
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    SNUPN deficiency causes a recessive muscular dystrophy due to RNA mis-splicing and ECM dysregulation
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    nature.com/articles/s41467-024-45933-5
  6. Feb 2024
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    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    sciencedirect.com/science/article/pii/S1097276524000984
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    Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896134/
  9. 52.53.155.43 52.53.155.43
    Identification of high-performing antibodies for SPARC-related modular calcium-binding protein 1 (SMOC-1) for use in Western Blot and immunoprecipitation
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    52.53.155.43/c64b3707ad512c5ae0e1da5ea9afe6057193130c/d14-html.html
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17088
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    First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors
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    aacrjournals.org/clincancerres/article/30/3/506/733551/First-in-Human-Study-with-Preclinical-Data-of-BCL
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    Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts
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    nature.com/articles/s43587-024-00575-6
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    Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities
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    ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
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    Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex
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    p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome
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    Mouse oocytes sequester aggregated proteins in degradative super-organelles
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    Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34883
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    The sequence of events of enteropathogenic E. coli’s type III secretion system translocon assembly
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    Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells
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    Aspartate β-hydroxylase Regulates Expression of Ly6 Genes
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    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
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    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
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    Comparative analysis of methodologies for detecting extrachromosomal circular DNA
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    biorxiv.org/content/10.1101/2023.12.01.569546v1
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    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    Mieap forms membrane-less organelles involved in cardiolipin metabolism
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    Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signaling
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17081
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    The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16062
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    DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17064
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    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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    sciencedirect.com/science/article/pii/S2451945624000382
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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    Nudt21-mediated alternative polyadenylation of MZT1 3’UTR contributes to pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831950/
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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  39. Jan 2024
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    HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling
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    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
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    Increased Serum Interleukin 10 Levels Are Associated with Increased Disease Activity and Increased Risk of Anti-SS-A/Ro Antibody Positivity in Patients with Systemic Lupus Erythematosus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10296207/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MCAK Inhibitors Induce Aneuploidy in Triple-Negative Breast Cancer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10340532/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PepFect14 mediates the delivery of mRNA into human primary keratinocytes and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10374019/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798561/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interaction of PINK1 with nucleotides and kinetin
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798554/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798859/
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    Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13577
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H2O2 Activation of Syk/PI3K/Akt Signaling Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788729/
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    Arrestin-3 binds parkin and enhances parkin-dependent mitophagy
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16043
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    Mechano-regulation by clathrin pit-formation and passive cholesterol-dependent tubules during de-adhesion
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    link.springer.com/article/10.1007/s00018-023-05072-4
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10777466/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated Serum Levels of Soluble Transferrin Receptor Are Associated with an Increased Risk of Cardiovascular, Pulmonary, and Hematological Manifestations and a Decreased Risk of Neuropsychiatric Manifestations in Systemic Lupus Erythematosus Patients
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13563
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    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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    sciencedirect.com/science/article/pii/S002228362300551X
  58. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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  59. Dec 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite
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    A rapid isothermal CRISPR‒Cas13a diagnostic test for genital Herpes simplex virus infection.
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    sciencedirect.com/science/article/pii/S2211124723015930
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10723637/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Moesin for use in Western Blot, immunoprecipitation, and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10724652/
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    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
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    SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer
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    The roles of FUS-RNA binding domain and low complexity domain in RNA-dependent phase separation
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    sciencedirect.com/science/article/pii/S0969212623004082
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    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
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    Investigation of the mixed origins of the MGC-803 cell line reveals that it is a hybrid cell line derived from HeLa
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    link.springer.com/article/10.1007/s13577-023-01011-4
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    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
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    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10711208/
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    The impact of cycling hypoxia on the phenotype of HPV-positive cervical cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/jmv.29280
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Highlights from MBoC Selection: Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10559312/
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    Exploiting the endogenous yeast nuclear proteome to identify short linear motifs in vivo
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    sciencedirect.com/science/article/pii/S2667237523003089
  78. www.biorxiv.org www.biorxiv.org
    Spartin-mediated lipid transfer facilitates lipid droplet turnover
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    biorxiv.org/content/10.1101/2023.11.29.569220v1
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    Revisiting the role of endogenous STAT3 in HPV-positive cervical cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/jmv.29230
  80. Nov 2023
  81. www.sciencedirect.com www.sciencedirect.com
    Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
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    sciencedirect.com/science/article/pii/S2211124723014663
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    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
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    sciencedirect.com/science/article/pii/S2211124723014961
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    Extensive elimination of acinar cells during normal postnatal pancreas growth
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    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
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    link.springer.com/article/10.1007/s00018-023-05011-3
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    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
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    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    sciencedirect.com/science/article/pii/S2451945623003719
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
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  178. May 2023
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  182. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antitumor activity of galaxamide involved in cell apoptosis and stemness by inhibiting Wnt/β-catenin pathway in cervical cancer
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    onlinelibrary.wiley.com/doi/10.1002/ddr.22073
  183. journals.biologists.com journals.biologists.com
    The Salmonella effector SifA initiates a kinesin-1 and kinesin-3 recruitment process mirroring that mediated by Arl8a/b
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    A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation
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  188. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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  189. www.biorxiv.org www.biorxiv.org
    Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins
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  190. Apr 2023
  191. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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    ZFP36-mediated mRNA decay regulates metabolism
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    Full-length circular RNA profiling by nanopore sequencing with CIRI-long
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    Possible frequent multiple mitochondrial DNA copies in a single nucleoid in HeLa cells
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    The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
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    A general method for quantitative fractionation of mammalian cells
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    Histone H3 phospho-regulation by KimH3 in both interphase and mitosis
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  200. Mar 2023
  201. www.biorxiv.org www.biorxiv.org
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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    Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments
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    The acetylase activity of Cdu1 protects Chlamydia effectors from degradation to regulate bacterial exit from infected cells
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    biorxiv.org/content/10.1101/2023.02.28.530337v2
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    GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region
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