1,807 Matching Annotations
  1. Jul 2024
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    Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
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    Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach
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    sciencedirect.com/science/article/pii/S1097276524005288
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    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    Spartin-mediated lipid transfer facilitates lipid droplet turnover
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    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
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    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    Assembly and activation of EBV latent membrane protein 1
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    Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution
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    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
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  15. Jun 2024
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    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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    Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy
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    Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity
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    A Gene‐Switch Platform Interfacing with Reactive Oxygen Species Enables Transcription Fine‐Tuning by Soluble and Volatile Pharmacologics and Food Additives
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    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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  26. May 2024
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    hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing
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    Ferroptosis induces membrane blebbing in placental trophoblasts
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    Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques
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    New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets
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    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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    Multiple ubiquitin ligases protect human genome integrity by targeting cancer-associated APOBEC3 deaminases for degradation
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  50. Apr 2024
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    The Zn2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila
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    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    Repurposing AS1411 for constructing ANM-PROTACs
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    Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
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    Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA mimicry and histone chaperone efficiency
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    Nrf2 pre-recruitment at Enhancer 2 is a hallmark of H2 O2 -induced epigenetic transcriptional memory in the HMOX1 gene in human umbilical artery endothelial cells
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    The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
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    Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation
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    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
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    A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein
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  76. Mar 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
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    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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    CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans
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    CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans
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    Light-mediated intracellular polymerization
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    Paradoxical imbalance between activated lymphocyte protein synthesis capacity and rapid division rate
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    Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1
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    Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
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    FLEX: genetically encodable enzymatic fluorescence signal amplification using engineered peroxidase
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    The Golgi checkpoint: Golgi unlinking during G2 is necessary for spindle formation and cytokinesis
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    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling
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