1,227 Matching Annotations
  1. Jul 2024
  2. www.mdpi.com www.mdpi.com
    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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    mdpi.com/1422-0067/25/13/7475
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NDRG1 acts as an oncogene in triple-negative breast cancer and its loss sensitizes cells to mitochondrial iron chelation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11231402/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11215406/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  6. Jun 2024
  7. jast-journal.springeropen.com jast-journal.springeropen.com
    Nail fold capillaroscopy as a potential tool to evaluate breast tumor
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    jast-journal.springeropen.com/articles/10.1186/s40543-024-00449-x
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An electro-optical platform for the ultrasensitive detection of small extracellular vesicle sub-types and their protein epitope counts
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152657/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145169/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11136494/
  11. May 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  13. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    nature.com/articles/s41416-024-02697-5
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17158
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    mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
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    sciencedirect.com/science/article/pii/S1097276524003939
  16. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  18. www.biorxiv.org www.biorxiv.org
    Activation of PKR by a short-hairpin RNA
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    biorxiv.org/content/10.1101/2024.05.08.592371v1
  19. www.sciencedirect.com www.sciencedirect.com
    Protocol for mapping physiological DSBs using in-suspension break labeling in situ and sequencing
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    sciencedirect.com/science/article/pii/S2666166724002247
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089195/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
  22. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17145
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071257/
  24. www.sciencedirect.com www.sciencedirect.com
    Targeted blocking of EGFR and GLUT1 by compound H reveals a new strategy for treatment of triple-negative breast cancer and nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S0928098724001003
  25. www.sciencedirect.com www.sciencedirect.com
    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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    sciencedirect.com/science/article/pii/S2211124724005023
  26. link.springer.com link.springer.com
    A novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer
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    link.springer.com/article/10.1038/s41419-024-06675-w
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811747/
  28. Apr 2024
  29. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  30. link.springer.com link.springer.com
    Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines
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    link.springer.com/article/10.1186/s12885-024-12214-9
  31. www.embopress.org www.embopress.org
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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    embopress.org/doi/10.1038/s44318-024-00065-w
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  35. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    sciencedirect.com/science/article/pii/S221112472400439X
  36. link.springer.com link.springer.com
    Functionalized siRNA-chitosan nanoformulations promote triple-negative breast cancer cell death via blocking the miRNA-21/AKT/ERK signaling axis: in-silico and in vitro studies
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    link.springer.com/article/10.1007/s00210-024-03068-w
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23706
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
  39. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    sciencedirect.com/science/article/pii/S1535610824000916
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abemaciclib is effective in palbociclib-resistant hormone receptor-positive metastatic breast cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10592446/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984980/
  42. Mar 2024
  43. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    nature.com/articles/s41596-024-00970-8
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eukaryotic release factor 1 from Euplotes promotes frameshifting at premature stop codons in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952039/
  45. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    sciencedirect.com/science/article/pii/S2211124724003000
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF217 Gene Copy Number as a Marker of Response to Standard Therapy Drugs According to ERα Status in Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10950081/
  47. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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    biorxiv.org/content/10.1101/2024.03.03.583221v1
  48. www.sciencedirect.com www.sciencedirect.com
    MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2405844024042038
  49. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  50. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
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    sciencedirect.com/science/article/pii/S0092867424002265
  51. www.sciencedirect.com www.sciencedirect.com
    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    sciencedirect.com/science/article/pii/S2589004224004097
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902018/
  55. www.biorxiv.org www.biorxiv.org
    The transcription factor RIP140 regulates interferon γ signaling in breast cancer
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    biorxiv.org/content/10.1101/2024.02.15.580503v1
  56. Feb 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896134/
  58. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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    52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870201/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TOP1 and R-loops facilitate transcriptional DSBs at hypertranscribed cancer driver genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875566/
  61. link.springer.com link.springer.com
    Effectiveness of [67Cu]Cu-trastuzumab as a theranostic against HER2-positive breast cancer
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    link.springer.com/article/10.1007/s00259-024-06648-3
  62. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    sciencedirect.com/science/article/pii/S1097276524000893
  63. www.sciencedirect.com www.sciencedirect.com
    Increased matrix stiffness enhances pro-tumorigenic traits in a physiologically relevant breast tissue- monocyte 3D model
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    sciencedirect.com/science/article/pii/S1742706124000898
  64. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Krüppel-like factor 9 (KLF9) links hormone dysregulation and circadian disruption to breast cancer pathogenesis
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    cancerci.biomedcentral.com/articles/10.1186/s12935-023-02874-1
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aspartate β-hydroxylase Regulates Expression of Ly6 Genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10861829/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial regulation by ERK1/2 and CK1δ protein kinases leads to HIF-1α association with microtubules and facilitates its symmetrical distribution during mitosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10834586/
  68. link.springer.com link.springer.com
    Functionalized tetrahedral DNA frameworks for the capture of circulating tumor cells
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    link.springer.com/article/10.1038/s41596-023-00943-3
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34859
  70. www.sciencedirect.com www.sciencedirect.com
    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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    sciencedirect.com/science/article/pii/S2666979X24000259
  71. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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    sciencedirect.com/science/article/pii/S1550413124000056
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10829383/
  73. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424000102
  74. Jan 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabis sativa L. modulates altered metabolic pathways involved in key metabolisms in human breast cancer (MCF-7) cells: A metabolomics study
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    ncbi.nlm.nih.gov/pmc/articles/PMC10196869/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analyzing the role of cancer‐associated fibroblast activation on macrophage polarization
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    ncbi.nlm.nih.gov/pmc/articles/PMC10399715/
  78. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
  79. www.sciencedirect.com www.sciencedirect.com
    Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer
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    sciencedirect.com/science/article/pii/S2211124724000123
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10790128/
  81. www.sciencedirect.com www.sciencedirect.com
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    sciencedirect.com/science/article/pii/S0304383524000296
  82. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17044
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC10693625/
  84. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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    sciencedirect.com/science/article/pii/S1934590923004320
  85. www.sciencedirect.com www.sciencedirect.com
    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2211124723016558
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GRB2 is a BECN1 interacting protein that regulates autophagy.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10770341/
  87. www.sciencedirect.com www.sciencedirect.com
    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413123004552
  88. www.sciencedirect.com www.sciencedirect.com
    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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    sciencedirect.com/science/article/pii/S2211124723016522
  89. Dec 2023
  90. www.nature.com www.nature.com
    Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho
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    nature.com/articles/s41388-023-02904-2
  91. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.14774
  92. www.biorxiv.org www.biorxiv.org
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    biorxiv.org/content/10.1101/2023.11.15.567291v1
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10683240/
  94. Nov 2023
  95. www.cell.com www.cell.com
    Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
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    cell.com/molecular-cell/fulltext/S1097-2765(23)00857-2
  96. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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  196. Jan 2023
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  213. Nov 2022
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