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899 Matching Annotations

May 2022
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Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors

1
1. scibot 26 May 2022
  
  in Public
  
  The Jackson LaboratoryCat#005557
  
  DOI: 10.1016/j.celrep.2022.110839
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S221112472200612X
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ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1

1
1. scibot 26 May 2022
  
  in Public
  
  The Jackson Laboratory005557
  
  DOI: 10.1016/j.molcel.2022.04.034
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S1097276522004348
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c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity

1
1. scibot 19 May 2022
  
  in Public
  
  Jackson Laboratory005557
  
  DOI: 10.1016/j.isci.2022.104325
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S258900422200596X
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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

1
1. scibot 19 May 2022
  
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  JACKSON LABORATORYStock #: 005557
  
  DOI: 10.1016/j.celrep.2022.110814
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S221112472200585X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Matricellular protein WISP2 is an endogenous inhibitor of collagen linearization and cancer metastasis

1
1. scibot 18 May 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/0008-5472.CAN-20-3982
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8595651/
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Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling

1
1. scibot 18 May 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.cmet.2022.04.012
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413122001826
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

1
1. scibot 12 May 2022
  
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  Jackson Laboratories#005557
  
  DOI: 10.1016/j.cell.2022.04.019
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S0092867422004664
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Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
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  JAX:005557
  
  DOI: 10.1016/j.stem.2022.04.007
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590922001606
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Patient-derived models of brain metastases recapitulate human disseminated disease

1
1. scibot 05 May 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.xcrm.2022.100623
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2666379122001409
Apr 2022
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Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization

1
1. scibot 29 Apr 2022
  
  in Public
  
  The Jackson LaboratoryStrain: 005557
  
  DOI: 10.1016/j.devcel.2022.04.010
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1534580722002507
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SynNotch CAR Circuits Enhance Solid Tumor Recognition and Promote Persistent Anti-tumor Activity in Mouse Models

1
1. scibot 29 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1126/scitranslmed.abd8836
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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ncbi.nlm.nih.gov/pmc/articles/PMC8594452/
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The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma

1
1. scibot 28 Apr 2022
  
  in Public
  
  Jackson Laboratoriesstrain 005557
  
  DOI: 10.1016/j.devcel.2022.04.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S153458072200243X
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Enhanced safety and efficacy of protease-regulated CAR-T cell receptors

1
1. scibot 28 Apr 2022
  
  in Public
  
  Jackson Laboratory005557
  
  DOI: 10.1016/j.cell.2022.03.041
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S0092867422003919
www.science.org www.science.org

SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models

1
1. scibot 28 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1126/scitranslmed.abd8836
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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science.org/doi/full/10.1126/scitranslmed.abd8836
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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes

1
1. scibot 22 Apr 2022
  
  in Public
  
  Jackson Laboratory005557
  
  DOI: 10.1016/j.stem.2022.03.015
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590922001503
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The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function

1
1. scibot 22 Apr 2022
  
  in Public
  
  Jackson LaboratoryJax: 005557
  
  DOI: 10.1016/j.cmet.2022.03.013
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1550413122001279
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Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

1
1. scibot 22 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2022.04.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S153561082200157X
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Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche

1
1. scibot 21 Apr 2022
  
  in Public
  
  The Jackson LaboratoryStrain #:005557
  
  DOI: 10.1016/j.cell.2022.03.033
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S0092867422003439
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Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis

1
1. scibot 21 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.cell.2022.03.030
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S0092867422003403
www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu

Modular design of synthetic receptors for programmed gene regulation in cell therapies

1
1. scibot 20 Apr 2022
  
  in Public
  
  Jackson LaboratoriesCat#005557
  
  DOI: 10.1016/j.cell.2022.03.023
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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www-sciencedirect-com.ezp-prod1.hul.harvard.edu/science/article/pii/S0092867422003336
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer

1
1. scibot 09 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1038/s41467-022-29400-7
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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ncbi.nlm.nih.gov/pmc/articles/PMC8980049/
www.sciencedirect.com www.sciencedirect.com

Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment

1
1. scibot 08 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2022.03.004
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590922001023
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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

1
1. scibot 07 Apr 2022
  
  in Public
  
  Jackson#005557
  
  DOI: 10.1016/j.celrep.2022.110641
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S221112472200393X
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Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

1
1. scibot 07 Apr 2022
  
  in Public
  
  Jackson LaboratoriesCat# 005557
  
  DOI: 10.1016/j.celrep.2022.110637
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124722003898
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Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors

1
1. scibot 07 Apr 2022
  
  in Public
  
  The Jackson Laboratory; OCI colonyCat#005557
  
  DOI: 10.1016/j.celrep.2022.110621
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124722003692
aacrjournals.org aacrjournals.org

mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment

1
1. scibot 07 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/1541-7786.MCR-20-0799
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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aacrjournals.org/mcr/article/19/4/717/672854/mDKN-01-a-Novel-Anti-DKK1-mAb-Enhances-Innate
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Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy

2
1. scibot 07 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2022.110634
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
2. scibot 07 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005
  
  DOI: 10.1016/j.celrep.2022.110634
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124722003862
aacrjournals.org aacrjournals.org

Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia

1
1. scibot 05 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/2159-8290.CD-21-0692
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
Mar 2022
www.nature.com www.nature.com

ADARs act as potent regulators of circular transcriptome in cancer

1
1. scibot 26 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1038/s41467-022-29138-2
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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nature.com/articles/s41467-022-29138-2
www.sciencedirect.com www.sciencedirect.com

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

1
1. scibot 18 Mar 2022
  
  in Public
  
  Jackson LaboratoryStock No: 005557
  
  DOI: 10.1016/j.cmet.2022.02.009
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1550413122000535
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Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function

1
1. scibot 18 Mar 2022
  
  in Public
  
  Jackson labscat#: 005557
  
  DOI: 10.1016/j.stem.2022.02.010
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590922000613
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3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells

1
1. scibot 18 Mar 2022
  
  in Public
  
  Jackson LaboratoryStrain #005557
  
  DOI: 10.1016/j.stem.2022.02.009
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590922000601
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML

1
1. scibot 09 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2022.110481
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124722002145
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Tumor-derived Jagged1 promotes cancer progression through immune evasion

1
1. scibot 09 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2022.110492
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S221112472200225X
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CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

1
1. scibot 02 Mar 2022
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.ccell.2022.02.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1535610822000368
Feb 2022
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A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

1
1. scibot 23 Feb 2022
  
  in Public
  
  Jackson LaboratoryCat# 005557
  
  DOI: 10.1016/j.molcel.2022.01.022
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S1097276522000879
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Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination

1
1. scibot 16 Feb 2022
  
  in Public
  
  The Jackson Laboratory005557
  
  DOI: 10.1016/j.celrep.2022.110388
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124722001097
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Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth

1
1. scibot 13 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.medj.2021.12.008
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2666634021004098
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Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants

2
1. scibot 11 Feb 2022
  
  in Public
  
  005557
  
  DOI: 10.1016/j.celrep.2022.110322
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
2. scibot 09 Feb 2022
  
  in Public
  
  005557
  
  DOI: 10.1016/j.celrep.2022.110322
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S221112472200033X
link.springer.com link.springer.com

When left does not seem right: epigenetic and bioelectric differences between left- and right-sided breast cancer

1
1. scibot 08 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1186/s10020-022-00440-5
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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link.springer.com/article/10.1186/s10020-022-00440-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer.

1
1. scibot 02 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/0008-5472.CAN-20-1200
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7854521/
Jan 2022
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Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells

1
1. scibot 27 Jan 2022
  
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  #005557
  
  DOI: 10.1016/j.devcel.2021.12.020
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1534580721010406
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Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions

1
1. scibot 16 Jan 2022
  
  in Public
  
  The Jackson LaboratoryCat# 005557
  
  DOI: 10.1016/j.crmeth.2021.100153
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2667237521002307
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SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

1
1. scibot 12 Jan 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 005557
  
  DOI: 10.1016/j.celrep.2021.110233
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124721017423
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Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness

1
1. scibot 05 Jan 2022
  
  in Public
  
  Cat#005557
  
  DOI: 10.1016/j.cmet.2021.12.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S1550413121006203
Dec 2021
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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity

1
1. scibot 31 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2021.12.005
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1535610821006589
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EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion

1
1. scibot 28 Dec 2021
  
  in Public
  
  Stock No. 005557
  
  DOI: 10.1016/j.cell.2021.12.005
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S0092867421014276
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An NK-like CAR T cell transition in CAR T cell dysfunction

1
1. scibot 03 Dec 2021
  
  in Public
  
  Cat# 5557
  
  DOI: 10.1016/j.cell.2021.11.016
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S0092867421013313
www.nature.com www.nature.com

Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

1
1. scibot 03 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1038/s42003-021-02842-3
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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nature.com/articles/s42003-021-02842-3
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer

1
1. scibot 01 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1126/scitranslmed.abb3738
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8627689/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Immuno-transcriptomic profiling of extracranial pediatric solid malignancies

1
1. scibot 30 Nov 2021
  
  in Public
  
  Stock No: 005557
  
  DOI: 10.1016/j.celrep.2021.110047
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721015333
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Distinct contributions of partial and full EMT to breast cancer malignancy

1
1. scibot 30 Nov 2021
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.devcel.2021.11.006
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1534580721008911
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Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities

1
1. scibot 24 Nov 2021
  
  in Public
  
  Stock# 005557
  
  DOI: 10.1016/j.celrep.2021.110054
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124721015400
www.sciencedirect.com www.sciencedirect.com

Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

1
1. scibot 24 Nov 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.celrep.2021.110056
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124721015424
www.sciencedirect.com www.sciencedirect.com

Effective chimeric antigen receptor T-cells (CAR-Ts) against SARS-CoV-2

1
1. scibot 18 Nov 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.isci.2021.103295
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2589004221012645
www.sciencedirect.com www.sciencedirect.com

Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy

1
1. scibot 17 Nov 2021
  
  in Public
  
  Stock #: 005557
  
  DOI: 10.1016/j.xcrm.2021.100449
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2666379121003177
www.sciencedirect.com www.sciencedirect.com

A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors

1
1. scibot 09 Nov 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.celrep.2021.109953
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124721014303
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

1
1. scibot 05 Nov 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ebiom.2021.103646
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

1
1. scibot 05 Nov 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/2159-8290.CD-20-1243
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8406797/
Oct 2021
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Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

1
1. scibot 30 Oct 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.cell.2021.10.004
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S0092867421011788
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Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis

1
1. scibot 21 Oct 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.celrep.2021.109870
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124721013371
www.sciencedirect.com www.sciencedirect.com

Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer

1
1. scibot 21 Oct 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2021.109852
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S221112472101319X
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Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas

1
1. scibot 21 Oct 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2021.109873
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124721013401
www.science.org www.science.org

Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels

1
1. scibot 18 Oct 2021
  
  in Public
  
  005557
  
  DOI: 10.1126/sciadv.abi7511
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @bandrow
  
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science.org/doi/abs/10.1126/sciadv.abi7511
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Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer

1
1. scibot 18 Oct 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1126/scitranslmed.abb3738
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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science.org/doi/abs/10.1126/scitranslmed.abb3738
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels

1
1. scibot 15 Oct 2021
  
  in Public
  
  JAX stock #005557
  
  DOI: 10.1126/sciadv.abi7511
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8494442/
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Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells

1
1. scibot 13 Oct 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.celrep.2021.109812
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124721012766
Sep 2021
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NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

1
1. scibot 23 Sep 2021
  
  in Public
  
  Strain# 005557
  
  DOI: 10.1016/j.molcel.2021.08.034
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S1097276521007140
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Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging

1
1. scibot 21 Sep 2021
  
  in Public
  
  Stock# 005557
  
  DOI: 10.1016/j.celrep.2021.109689
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer

1
1. scibot 15 Sep 2021
  
  in Public
  
  005,557
  
  DOI: 10.1016/j.chembiol.2021.08.011
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2451945621004001
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Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy

1
1. scibot 15 Sep 2021
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.stem.2021.08.013
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1934590921003507
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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

1
1. scibot 14 Sep 2021
  
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  005557
  
  DOI: 10.1016/j.ccell.2021.08.009
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610821004499
Aug 2021
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Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

1
1. scibot 25 Aug 2021
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.celrep.2021.109568
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection

1
1. scibot 18 Aug 2021
  
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  Stock No: 005557
  
  DOI: 10.1016/j.celrep.2021.109538
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

1
1. scibot 16 Aug 2021
  
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  JAX:005557
  
  DOI: 10.1016/j.ccell.2021.07.006
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

1
1. scibot 16 Aug 2021
  
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  JAX:005557
  
  DOI: 10.1016/j.cell.2021.07.020
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/2159-8290.CD-20-0331
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8110214/
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Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

1
1. scibot 14 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2019.06.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression

1
1. scibot 11 Aug 2021
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.stem.2016.12.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
  in Public
  
  Stock No: 005557
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276521005876
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer

1
1. scibot 06 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.7554/eLife.43024
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6597241/
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Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft.

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/1541-7786.MCR-20-0686
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7864867/
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A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.7554/eLife.70429
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8321552/
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Untitled document

1
1. scibot 04 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2018.11.006
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1535610818305270
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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

1
1. scibot 04 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2021.07.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1934590921002885
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Untitled document

1
1. scibot 04 Aug 2021
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.stem.2016.12.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5822422/
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The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer

1
1. scibot 03 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.molcel.2017.11.025
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1097276517308845
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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation

1
1. scibot 03 Aug 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2018.06.012
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1535610818302691
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The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2019.05.069
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124719306989
Jul 2021
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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

1
1. scibot 31 Jul 2021
  
  in Public
  
  Mouse: NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG)
  
  DOI: 10.1016/j.ccell.2019.11.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610819305215
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TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2021.07.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819300406
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Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2019.02.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819300984
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Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body

1
1. scibot 30 Jul 2021
  
  in Public
  
  Jackson Laboratory005557
  
  DOI: 10.1016/j.cell.2019.11.013
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S0092867419312693
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N6-methyladenine DNA Modification in Glioblastoma

1
1. scibot 30 Jul 2021
  
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  JAX:005557
  
  DOI: 10.1016/j.cell.2018.10.006
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Jmenke
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S009286741831314X
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.cell.2018.09.051
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Jmenke
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S0092867418312637
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Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

1
1. scibot 30 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.devcel.2018.10.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1534580718308220
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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2018.08.018
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590918304363
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Metabolic Rewiring in Response to Biguanides Is Mediated by mROS/HIF-1a in Malignant Lymphocytes

1
1. scibot 29 Jul 2021
  
  in Public
  
  Jackson LaboratoryStock No:#005557
  
  DOI: 10.1016/j.celrep.2019.11.007
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson LaboratoryCat#005557
  
  DOI: 10.1016/j.stem.2019.10.005
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1934590919304266
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Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson LaboratoryStock# 005557
  
  DOI: 10.1016/j.celrep.2019.08.076
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S2211124719311313
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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

1
1. scibot 29 Jul 2021
  
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  JAX : 005557
  
  DOI: 10.1016/j.ccell.2019.08.005
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1535610819303733
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Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson LaboratoryStock #: 005557
  
  DOI: 10.1016/j.stem.2019.08.004
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S193459091930339X
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LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

1
1. scibot 29 Jul 2021
  
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  The Jackson LaboratoryCat# 005557
  
  DOI: 10.1016/j.ccell.2019.07.007
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1535610819303344
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Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

1
1. scibot 29 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.molcel.2019.06.045
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1097276519305027
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An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

1
1. scibot 29 Jul 2021
  
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  Jackson laboratoryCat#5557
  
  DOI: 10.1016/j.cell.2019.06.024
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S0092867419306877
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Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

1
1. scibot 29 Jul 2021
  
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  RRID: IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2019.06.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1535610819302946
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Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

1
1. scibot 29 Jul 2021
  
  in Public
  
  Mouse: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG)
  
  DOI: 10.1016/j.celrep.2019.05.092
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124719307314
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

1
1. scibot 29 Jul 2021
  
  in Public
  
  Mouse strain: NSG; NOD.Cg-PrkdcscidIL2rgtm1Wjl/ Szj
  
  DOI: 10.1016/j.celrep.2019.07.027
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124719309246
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Untitled document

1
1. scibot 29 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1002/cpmo.38
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpmo.38
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Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying hemizygous 208insC mutations in the IDS gene

1
1. scibot 28 Jul 2021
  
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  JAX No. 005557
  
  DOI: 10.1016/j.scr.2019.101451
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1873506119300819
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection

1
1. scibot 28 Jul 2021
  
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  005557
  
  DOI: 10.1186/s12865-018-0279-3
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6322283/
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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling

1
1. scibot 28 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.ccell.2018.11.016
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1535610818305373
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A Myogenic Double-Reporter Human Pluripotent Stem Cell Line Allows Prospective Isolation of Skeletal Muscle Progenitors

1
1. scibot 28 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.celrep.2018.10.067
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6287935/
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IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation

1
1. scibot 27 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.stem.2018.10.016
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Jmenke
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

1
1. scibot 27 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.celrep.2018.10.100
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124718317224
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Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2

1
1. scibot 27 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.chembiol.2018.10.009
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Jmenke
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2451945618303428
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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

1
1. scibot 27 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.ccell.2018.10.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1535610818304677
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Untitled document

1
1. scibot 27 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2018.11.032
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2211124718317959
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Untitled document

1
1. scibot 27 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2018.07.009
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S193459091830345X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Distinct skeletal stem cell types orchestrate long bone skeletogenesis

1
1. scibot 23 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.7554/eLife.66063
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8289409/
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Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis

1
1. scibot 22 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2021.06.004
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1934590921002745
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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
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  RRID:IMSR_JAX005557
  
  DOI: 10.1016/j.xcrm.2021.100350
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mus musculus IMSR Cat# JAX:005557
  
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  RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2666379121001993
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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells

1
1. scibot 21 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.molcel.2021.06.027
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S1097276521005074
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A universal gene correction approach for FKRP-associated dystroglycanopathies to enable autologous cell therapy

1
1. scibot 14 Jul 2021
  
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  005557
  
  DOI: 10.1016/j.celrep.2021.109360
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC8327854/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth

1
1. scibot 14 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/1535-7163.MCT-20-0480
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7611204/
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Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides

1
1. scibot 09 Jul 2021
  
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  Cat # 005557
  
  DOI: 10.1016/j.celrep.2021.109312
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721006884
elifesciences.org elifesciences.org

Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction

1
1. scibot 01 Jul 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.7554/eLife.62927
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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elifesciences.org/articles/62927
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction

1
1. scibot 18 Jun 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.isci.2021.102544
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8184503/
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Metabolic imaging with hyperpolarized [1-13C] pyruvate in patient-derived preclinical mouse models of breast cancer

1
1. scibot 18 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.xpro.2021.100608
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
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sciencedirect.com/science/article/pii/S2666166721003154
journals.sagepub.com journals.sagepub.com

High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids - Nicholas Choo, Susanne Ramm, Jennii Luu, Jean M. Winter, Luke A. Selth, Amy R. Dwyer, Mark Frydenberg, Jeremy Grummet, Shahneen Sandhu, Theresa E. Hickey, Wayne D. Tilley, Renea A. Taylor, Gail P. Risbridger, Mitchell G. Lawrence, Kaylene J. Simpson, 2021

1
1. scibot 17 Jun 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1177/24725552211020668
  
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The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation

1
1. scibot 16 Jun 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2021.109252
  
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elifesciences.org elifesciences.org

Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree

1
1. scibot 15 Jun 2021
  
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  Stock 005557
  
  DOI: 10.7554/eLife.67776
  
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STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma

1
1. scibot 15 Jun 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2021.05.007
  
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Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G>A in the ACVR1 gene

1
1. scibot 08 Jun 2021
  
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  JAX No. 005557
  
  DOI: 10.1016/j.scr.2021.102424
  
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May 2021
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N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

1
1. scibot 28 May 2021
  
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  Stock No: 005557
  
  DOI: 10.1016/j.ccell.2021.04.017
  
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Charting human development using a multi-endodermal organ atlas and organoid models

1
1. scibot 21 May 2021
  
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  strain no. 0005557
  
  DOI: 10.1016/j.cell.2021.04.028
  
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Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility

1
1. scibot 20 May 2021
  
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  Stock No: 005557
  
  DOI: 10.1016/j.immuni.2021.04.020
  
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Dynamic BH3 profiling method for rapid identification of active therapy in BH3 mimetics resistant xenograft mouse models

1
1. scibot 14 May 2021
  
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  005557
  
  DOI: 10.1016/j.xpro.2021.100461
  
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Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation

1
1. scibot 12 May 2021
  
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  JAX 005557
  
  DOI: 10.1016/j.devcel.2021.02.025
  
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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption

1
1. scibot 09 May 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2020.12.017
  
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UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

1
1. scibot 09 May 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2020.12.002
  
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Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras

1
1. scibot 09 May 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2020.11.019
  
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LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis

1
1. scibot 09 May 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2020.06.017
  
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Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2020.07.003
  
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The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia

1
1. scibot 06 May 2021
  
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  JAX:005557
  
  DOI: 10.1016/j.isci.2021.102435
  
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cell.com/iscience/abstract/S2589-0042(21)00403-X
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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

1
1. scibot 05 May 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.devcel.2020.09.021
  
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Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells

1
1. scibot 04 May 2021
  
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  Jax Stock# 005557
  
  DOI: 10.1016/j.stem.2021.04.008
  
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Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth

1
1. scibot 01 May 2021
  
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  Cat# 005557
  
  DOI: 10.1016/j.cmet.2021.02.001
  
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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
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  JAX:005557
  
  DOI: 10.1016/j.cmet.2021.03.003
  
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Apr 2021
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Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells

1
1. scibot 30 Apr 2021
  
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  Stock#005557
  
  DOI: 10.1016/j.cmet.2020.10.025
  
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Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

1
1. scibot 29 Apr 2021
  
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  005557
  
  DOI: 10.1016/j.cmet.2020.10.017
  
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Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

1
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  DOI: 10.1016/j.cmet.2020.07.009
  
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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells

1
1. scibot 29 Apr 2021
  
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  Stock No: 005557
  
  DOI: 10.1016/j.cmet.2020.07.008
  
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The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development

1
1. scibot 29 Apr 2021
  
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  JAX- 005557
  
  DOI: 10.1016/j.cmet.2020.05.008
  
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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

1
1. scibot 29 Apr 2021
  
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  Stock No: 005557
  
  DOI: 10.1016/j.immuni.2021.04.002
  
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An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

1
1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2020.11.012
  
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Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma

1
1. scibot 28 Apr 2021
  
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  Cat#005557
  
  DOI: 10.1016/j.celrep.2021.109013
  
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
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  005557
  
  DOI: 10.1016/j.cell.2020.07.009
  
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Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

1
1. scibot 24 Apr 2021
  
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  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.cell.2021.01.022
  
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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies

1
1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.08.022
  
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Human KIT+ myeloid cells facilitate visceral metastasis by melanoma

1
1. scibot 24 Apr 2021
  
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  JAX:005557
  
  DOI: 10.1084/jem.20182163
  
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rupress.org/jem/article/218/6/e20182163/211995/Human-KIT-myeloid-cells-facilitate-visceral
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MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism

1
1. scibot 22 Apr 2021
  
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  005557
  
  DOI: 10.1016/j.ccell.2021.02.006
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610821001082
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A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

1
1. scibot 22 Apr 2021
  
  in Public
  
  Ref 5557
  
  DOI: 10.1016/j.ccell.2021.02.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610821001057
www.sciencedirect.com www.sciencedirect.com

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

1
1. scibot 22 Apr 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.ccell.2020.10.010
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610820305419
www.sciencedirect.com www.sciencedirect.com

Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance

1
1. scibot 22 Apr 2021
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.ccell.2020.12.023
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1535610820306711
www.cell.com www.cell.com

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

1
1. scibot 20 Apr 2021
  
  in Public
  
  005557
  
  DOI: 10.1016/j.ccell.2020.06.012
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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cell.com/cancer-cell/fulltext/S1535-6108(20)30316-0
www.sciencedirect.com www.sciencedirect.com

Mass spectrometry analysis of circulating breast cancer cells from a Xenograft mouse model

1
1. scibot 20 Apr 2021
  
  in Public
  
  Cat# 5557
  
  DOI: 10.1016/j.xpro.2021.100480
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2666166721001878
www.sciencedirect.com www.sciencedirect.com

Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2020.07.008
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S153561082030369X
www.sciencedirect.com www.sciencedirect.com

SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

1
1. scibot 17 Apr 2021
  
  in Public
  
  Strain# 005557
  
  DOI: 10.1016/j.ccell.2020.04.014
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1535610820302130
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2020.04.017
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1535610820302166
www.sciencedirect.com www.sciencedirect.com

Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma

1
1. scibot 11 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2021.02.003
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590921000539
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells

1
1. scibot 28 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1158/2643-3230.BCD-20-0161
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
Feb 2021
www.nature.com www.nature.com

Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1038/s41418-020-00733-4
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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nature.com/articles/s41418-020-00733-4
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.7554/eLife.61980
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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ncbi.nlm.nih.gov/pmc/articles/PMC7847306/
www.cell.com www.cell.com

Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2021.01.004
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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cell.com/cell-stem-cell/abstract/S1934-5909(21)00004-7
www.sciencedirect.com www.sciencedirect.com

Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2021.01.016
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S1934590921000163
insight.jci.org insight.jci.org

Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells

1
1. scibot 14 Feb 2021
  
  in Public
  
  S
  
  DOI: 10.1172/jci.insight.130510
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557
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insight.jci.org/articles/view/130510/sd/1
www.sciencedirect.com www.sciencedirect.com

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)

1
1. scibot 03 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ebiom.2021.103220
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S235239642100013X
www.sciencedirect.com www.sciencedirect.com

Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

1
1. scibot 01 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.cell.2020.11.012
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867420315294
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

1
1. scibot 07 Jan 2021
  
  in Public
  
  Cat# 005557
  
  DOI: 10.1016/j.celrep.2020.108532
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124720315217
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Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression

1
1. scibot 07 Jan 2021
  
  in Public
  
  NSG mice
  
  DOI: 10.1016/j.celrep.2020.108522
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124720315114
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Tracking HIV Rebound following Latency Reversal Using Barcoded HIV

1
1. scibot 24 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.xcrm.2020.100162
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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RRID:IMSR_JAX:005557

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sciencedirect.com/science/article/pii/S2666379120302093
www.sciencedirect.com www.sciencedirect.com

Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation

1
1. scibot 24 Dec 2020
  
  in Public
  
  JAX:005557
  
  DOI: 10.1016/j.celrep.2020.108535
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124720315242
www.sciencedirect.com www.sciencedirect.com

Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells

1
1. scibot 15 Dec 2020
  
  in Public
  
  NOD-scidIL2Rgammanull
  
  DOI: 10.1016/j.celrep.2020.108482
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mus musculus IMSR Cat# JAX:005557
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124720314716
www.sciencedirect.com www.sciencedirect.com

Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis

1
1. scibot 15 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2020.108473
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRID:IMSR_JAX:005557

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sciencedirect.com/science/article/pii/S2211124720314625
www.sciencedirect.com www.sciencedirect.com

The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State

1
1. scibot 13 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2020.108474
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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sciencedirect.com/science/article/pii/S2211124720314637
link.springer.com link.springer.com

Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo

1
1. scibot 07 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1007/s00262-020-02780-9
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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link.springer.com/article/10.1007/s00262-020-02780-9
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

1
1. scibot 25 Nov 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.xcrm.2020.100131
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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RRID:IMSR_JAX:005557

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sciencedirect.com/science/article/pii/S2666379120301737
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis

1
1. scibot 10 Oct 2020
  
  in Public
  
  NOD-scid IL2Rgammanull (NSG) Mouse
  
  DOI: 10.1016/j.xpro.2020.100124
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mus musculus IMSR Cat# JAX:005557
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:005557
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URL

sciencedirect.com/science/article/pii/S2666166720301118
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction

1
1. scibot 26 Sep 2020
  
  in Public
  
  NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice
  
  DOI: 10.1016/j.xcrm.2020.100097
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mus musculus IMSR Cat# JAX:005557
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:005557
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pubmed.ncbi.nlm.nih.gov/33205073/
www.sciencedirect.com www.sciencedirect.com

Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.cell.2020.05.039
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  What is this?
  
  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRID:IMSR_JAX:005557

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sciencedirect.com/science/article/pii/S0092867420306723
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2020.02.002
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRID:IMSR_JAX:005557

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pubmed.ncbi.nlm.nih.gov/32142668/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.7554/eLife.56913
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  What is this?
  
  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRID:IMSR_JAX:005557

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ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
www.sciencedirect.com www.sciencedirect.com

Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

1
1. scibot 25 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2020.08.016
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
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  RRIDCUR:Validated RRID:IMSR_JAX:005557
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RRIDCUR:Validated

RRID:IMSR_JAX:005557

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scibot

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sciencedirect.com/science/article/pii/S153561082030427X
www.sciencedirect.com www.sciencedirect.com

Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.celrep.2020.107840
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  What is this?
  
  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:005557

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sciencedirect.com/science/article/pii/S2211124720308214
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A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.ccell.2020.03.004
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  What is this?
  
  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:005557

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scibot

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sciencedirect.com/science/article/pii/S1535610820301057
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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:005557
  
  DOI: 10.1016/j.stem.2020.02.001
  
  Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:005557
  
  What is this?
  
  RRID:IMSR_JAX:005557 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:005557

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scibot

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sciencedirect.com/science/article/pii/S1934590920300540

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