961 Matching Annotations
  1. Jan 2020
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    Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
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    Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands
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    CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies
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    The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation
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    Histone deacetylase 6 promotes growth of glioblastoma through the MKK7/JNK/c‐Jun signaling pathway
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    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
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    EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection
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    Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis
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    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
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    The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis
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    A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons
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    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
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    Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors
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    Systemic Root-Shoot Signaling Drives Jasmonate-Based Root Defense against Nematodes
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    Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6
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    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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      DOI: 10.1111/jnc.14874

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    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
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  21. elifesciences.org elifesciences.org
    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration
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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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  23. elifesciences.org elifesciences.org
    A bidirectional network for appetite control in larval zebrafish
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    Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis
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    Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes
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    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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    Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
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    IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer
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    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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  32. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
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    The Neuropeptide Galanin Is Required for Homeostatic Rebound Sleep following Increased Neuronal Activity
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly
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  35. www.jneurosci.org www.jneurosci.org
    FGF signaling directs the cell fate switch from neurons to astrocytes in the developing mouse cerebral cortex
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3
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    NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
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    3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival
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    FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling
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      DOI: 10.1038/s41598-018-36387-z

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    The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    Timing Mechanisms Underlying Gate Control by Feedforward Inhibition
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    Luminance Changes Drive Directional Startle through a Thalamic Pathway
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    Adaptive Fibrogenic Reprogramming of Osteosarcoma Stem Cells Promotes Metastatic Growth
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    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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    Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
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    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
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    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
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    Overcoming Resistance to Targeted Anticancer Therapies through Small-Molecule-Mediated MEK Degradation
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    Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
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    The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine
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    Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner
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    EF24 (a curcumin analog) and ZSTK474 emphasizes the effect of cabozantinib in medullary thyroid cancer
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    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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    A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability
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    Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer
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    Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
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    Different Neuronal Activity Patterns Induce Different Gene Expression Programs
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    Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation
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    A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability
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    Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting
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    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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    Crk proteins transduce FGF signaling to promote lens fiber cell elongation
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      Rabbit anti-pERK1/2Cell SignalingCat. #: 4370

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    Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines
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    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
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    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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    Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis
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    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
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    Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression
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  124. europepmc.org europepmc.org
    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
    1
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  125. www.sciencedirect.com www.sciencedirect.com
    Systems Phytohormone Responses to Mitochondrial Proteotoxic Stress
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  126. www.sciencedirect.com www.sciencedirect.com
    Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes
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  127. europepmc.org europepmc.org
    Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation.
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  128. www.sciencedirect.com www.sciencedirect.com
    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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  129. academic.oup.com academic.oup.com
    IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase
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  130. academic.oup.com academic.oup.com
    Region-Specific Suppression of Hypothalamic Responses to Insulin To Adapt to Elevated Maternal Insulin Secretion During Pregnancy
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  131. europepmc.org europepmc.org
    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.
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  132. Nov 2017
  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EPA blocks TNF‐α‐induced inhibition of sugar uptake in Caco‐2 cells via GPR120 and AMPK
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26115/full
  134. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of the GM1 ganglioside oligosaccharide portion in the TrkA–dependent neurite sprouting in neuroblastoma cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14146/full
  135. academic.oup.com academic.oup.com
    IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells
    1
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  136. www.sciencedirect.com www.sciencedirect.com
    Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria
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  137. www.sciencedirect.com www.sciencedirect.com
    Combinatorial Signal Perception in the BMP Pathway
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  138. f1000research.com f1000research.com
    Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity
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    f1000research.com/articles/6-1600
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes
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  140. www.sciencedirect.com www.sciencedirect.com
    CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc
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  141. www.sciencedirect.com www.sciencedirect.com
    Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis
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  142. www.sciencedirect.com www.sciencedirect.com
    Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C
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  143. www.sciencedirect.com www.sciencedirect.com
    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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    sciencedirect.com/science/article/pii/S1097276517304914
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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  145. www.jneurosci.org www.jneurosci.org
    ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase)
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  146. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
    1
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    sciencedirect.com/science/article/pii/S155041311730356X
  147. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A profile of auditory‐responsive neurons in the larval zebrafish brain
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    onlinelibrary.wiley.com/doi/10.1002/cne.24258/full
  148. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib
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  149. www.sciencedirect.com www.sciencedirect.com
    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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  150. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GLUL Promotes Cell Proliferation in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1002/jcb.25775/full
  151. www.sciencedirect.com www.sciencedirect.com
    Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation
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    sciencedirect.com/science/article/pii/S1534580717303507
  152. www.sciencedirect.com www.sciencedirect.com
    An Adenosine Receptor for Olfaction in Fish
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    sciencedirect.com/science/article/pii/S0960982217304232
  153. www.sciencedirect.com www.sciencedirect.com
    RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma
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  154. academic.oup.com academic.oup.com
    Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS
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  155. www.sciencedirect.com www.sciencedirect.com
    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
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      Curator: @kaitlinsung

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  156. www.sciencedirect.com www.sciencedirect.com
    A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos
    1
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    sciencedirect.com/science/article/pii/S1534580717300709
  157. www.sciencedirect.com www.sciencedirect.com
    Iterative Modeling Reveals Evidence of Sequential Transcriptional Control Mechanisms
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    sciencedirect.com/science/article/pii/S2405471217300121
  158. www.sciencedirect.com www.sciencedirect.com
    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biphasic Regulation of p38 MAPK by Serotonin Contributes to the Efficacy of Stimulus Protocols That Induce Long-Term Synaptic Facilitation
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  160. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis
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  161. www.sciencedirect.com www.sciencedirect.com
    Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells
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  162. www.sciencedirect.com www.sciencedirect.com
    Feeding State Modulates Behavioral Choice and Processing of Prey Stimuli in the Zebrafish Tectum
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
    1
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      RRID:AB_2315112
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    ncbi.nlm.nih.gov/pmc/articles/PMC4380931/
  164. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Anatomical evidence that the uninjured adjacent L4 nerve plays a significant role in the development of peripheral neuropathic pain after L5 spinal nerve ligation in rats
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    1. scibot 08 Nov 2017
      AB_2315112

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 4370, RRID:AB_2315112)

      SciCrunch record: RRID:AB_2315112

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2315112
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    onlinelibrary.wiley.com/doi/10.1002/cne.23750/full