Hypothesis

890 Matching Annotations

Sep 2020
www.cell.com www.cell.com

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID: CVCL_0006
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006
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RRID:CVCL_0006

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URL

cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
www.sciencedirect.com www.sciencedirect.com

Platelets Fuel the Inflammasome Activation of Innate Immune Cells

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP-1
  
  DOI: 10.1016/j.celrep.2020.107615
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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sciencedirect.com/science/article/pii/S2211124720305647
www.sciencedirect.com www.sciencedirect.com

SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation

1
1. scibot 04 Sep 2020
  
  in Public
  
  Human: THP-1 cells
  
  DOI: 10.1016/j.celrep.2020.02.105
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S2211124720302862
insight.jci.org insight.jci.org

The RNFT2/IL3Rα axis regulates IL3 signaling and innate immunity

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP-1
  
  DOI: 10.1172/jci.insight.133652
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  Curator comments: THP-1 cell line ATCC Cat# TIB-202
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

insight.jci.org/articles/view/133652
www.sciencedirect.com www.sciencedirect.com

hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP-1
  
  DOI: 10.1016/j.celrep.2020.107667
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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sciencedirect.com/science/article/pii/S2211124720306203
www.sciencedirect.com www.sciencedirect.com

Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP-1
  
  DOI: 10.1016/j.celrep.2020.01.064
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S2211124720300899
www.sciencedirect.com www.sciencedirect.com

TMEM173 Drives Lethal Coagulation in Sepsis

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP1
  
  DOI: 10.1016/j.chom.2020.02.004
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1931312820301128
www.sciencedirect.com www.sciencedirect.com

Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP1 (gender: male)
  
  DOI: 10.1016/j.chembiol.2020.02.003
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S2451945620300672
www.sciencedirect.com www.sciencedirect.com

Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization

1
1. scibot 04 Sep 2020
  
  in Public
  
  monocytic THP-1 cell line
  
  DOI: 10.1016/j.celrep.2019.12.091
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S2211124719317565
www.sciencedirect.com www.sciencedirect.com

Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression

1
1. scibot 04 Sep 2020
  
  in Public
  
  Human THP-1 cells
  
  DOI: 10.1016/j.molcel.2020.01.014
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S1097276520300149
www.sciencedirect.com www.sciencedirect.com

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

1
1. scibot 04 Sep 2020
  
  in Public
  
  THP-1 monocytes (human acute monocytic leukemia cell line)
  
  DOI: 10.1016/j.celrep.2020.02.056
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S2211124720302242
www.sciencedirect.com www.sciencedirect.com

Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis

1
1. scibot 04 Sep 2020
  
  in Public
  
  Human: THP1 cells
  
  DOI: 10.1016/j.cell.2020.02.002
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S009286742030146X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Recombinant Alkaline Phosphatase Prevents Acute on Chronic Liver Failure

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID: CVCL_0006
  
  DOI: 10.1038/s41598-019-57284-z
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006
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RRID:CVCL_0006

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC6962206/
www.nature.com www.nature.com

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

1
1. scibot 03 Sep 2020
  
  in Public
  
  ATCC TIB-202
  
  DOI: 10.1038/s41589-019-0424-1
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  Curator comments: THP-1 cell line ATCC Cat# TIB-202
  
  What is this?
  
  RRID:CVCL_0006
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RRID:CVCL_0006

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URL

nature.com/articles/s41589-019-0424-1
www.sciencedirect.com www.sciencedirect.com

Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2

1
1. scibot 03 Sep 2020
  
  in Public
  
  THP-1
  
  DOI: 10.1016/j.celrep.2020.02.007
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S2211124720301613
www.sciencedirect.com www.sciencedirect.com

Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34

1
1. scibot 03 Sep 2020
  
  in Public
  
  THP-1
  
  DOI: 10.1016/j.celrep.2020.01.088
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720301224
www.sciencedirect.com www.sciencedirect.com

Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP

1
1. scibot 03 Sep 2020
  
  in Public
  
  THP1 cells
  
  DOI: 10.1016/j.celrep.2020.108053
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  Curator comments: THP-1 cell line ATCC Cat# TIB-202
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S221112472031038X
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  TIB-202
  
  DOI: 10.1016/j.xcrm.2020.100039
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  Curator comments: THP-1
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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scibot

URL

pubmed.ncbi.nlm.nih.gov/33205061/
www.embopress.org www.embopress.org

Alveolar macrophage‐derived extracellular vesicles inhibit endosomal fusion of influenza virus

1
1. scibot 03 Sep 2020
  
  in Public
  
  TIB‐202
  
  DOI: 10.15252/embj.2020105057
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  Curator comments: THP-1 cell line ATCC Cat# TIB-202
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0006

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scibot

URL

embopress.org/doi/abs/10.15252/embj.2020105057
www.sciencedirect.com www.sciencedirect.com

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.immuni.2020.03.016
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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URL

sciencedirect.com/science/article/pii/S1074761320301291
Aug 2020
jitc.bmj.com jitc.bmj.com

IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma

1
1. scibot 25 Aug 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1136/jitc-2019-000285
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0006
  
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  RRID:CVCL_0006
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RRID:CVCL_0006

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scibot

URL

jitc.bmj.com/content/8/1/e000285
Jan 2020
www.sciencedirect.com www.sciencedirect.com

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2019.08.050
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719310988
www.sciencedirect.com www.sciencedirect.com

Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2019.06.074
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S221112471930854X
www.sciencedirect.com www.sciencedirect.com

Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.mce.2019.110654
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S0303720719303569
www.sciencedirect.com www.sciencedirect.com

Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.chom.2019.12.005
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S1931312819306341
www.sciencedirect.com www.sciencedirect.com

Fc Glycan-Mediated Regulation of Placental Antibody Transfer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.cell.2019.05.044
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419306154
www.cell.com www.cell.com

Atomic Structure of the Francisella T6SS Central Spike Reveals a Unique α-Helical Lid and a Putative Cargo

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.str.2019.10.007
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

cell.com/structure/fulltext/S0969-2126(19)30348-X
www.sciencedirect.com www.sciencedirect.com

Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2019.07.092
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719310083
www.sciencedirect.com www.sciencedirect.com

SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2019.06.027
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719307934
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1111/bph.14695
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14695
www.sciencedirect.com www.sciencedirect.com

Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.ccell.2019.05.003
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819302417
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Adaptation of Mammalian Cells to Chemically Defined Media

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1002/cptx.88
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cptx.88
www.sciencedirect.com www.sciencedirect.com

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2019.08.047
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719310952
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0006
  
  DOI: 10.1016/j.ccell.2019.04.006
  
  Resource: (RCB Cat# RCB1189, RRID:CVCL_0006)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0006
  
  What is this?
  
  RRID:CVCL_0006 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0006

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819302016
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cyto.2019.03.003
  
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  DOI: 10.7554/eLife.39823
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6286125/
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Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1111/bph.14465
  
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  DOI: 10.7554/eLife.41337
  
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SLC19A1 Is an Importer of the Immunotransmitter cGAMP

1
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  DOI: 10.1016/j.molcel.2019.05.006
  
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Inactivation of endothelial adenosine A2A receptors protects mice from cerebral ischaemia‐induced brain injury

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1111/bph.14673
  
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  DOI: 10.1016/j.celrep.2019.01.105
  
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  DOI: 10.1111/bph.14653
  
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

1
1. scibot 13 Jan 2020
  
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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.01.007
  
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Complement C4 Prevents Viral Infection through Capsid Inactivation

1
1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.chom.2019.02.016
  
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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

1
1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.ccell.2018.10.004
  
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Defining host–pathogen interactions employing an artificial intelligence workflow

1
1. scibot 12 Jan 2020
  
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  DOI: 10.7554/eLife.40560
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6372283/
Nov 2018
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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica

1
1. scibot 05 Nov 2018
  
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  THP-1
  
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Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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The Orphan G Protein‐coupled Receptor 75 Signaling is Activated by the Chemokine CCL5

1
1. scibot 05 Nov 2018
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14463
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NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation

1
1. scibot 05 Nov 2018
  
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The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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Mutant NPM1 Maintains the Leukemic State through HOX Expression

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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Transcription Elongation Can Affect Genome 3D Structure

1
1. scibot 05 Nov 2018
  
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Cationic lipids as one-component vaccine adjuvants: A promising alternative to alum

1
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Small-Molecule TLR8 Antagonists via Structure-Based Rational Design

1
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  TIB-202
  
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sciencedirect.com/science/article/pii/S2451945618302319
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A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

1
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Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

1
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Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

1
1. scibot 05 Nov 2018
  
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  TIB-202
  
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CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

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sciencedirect.com/science/article/pii/S1535610818302216
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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC5966397/
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Concentration-dependent protein loading of extracellular vesicles released by Histoplasma capsulatum after antibody treatment and its modulatory action upon macrophages

1
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nature.com/articles/s41598-018-25665-5
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The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells

1
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Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

1
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Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0006
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1074761317304879
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Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0006
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S0896627317310851
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Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0006
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1535610817305159
cardiab.biomedcentral.com cardiab.biomedcentral.com

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0006
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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cardiab.biomedcentral.com/articles/10.1186/s12933-017-0626-3
Nov 2017
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Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:CVCL_0006
  
  Curator: @Jmenke
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1535610817304087
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Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Jmenke
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1535610817303641
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Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Jmenke
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1097276517306536
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Boron-Based Inhibitors of the NLRP3 Inflammasome

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S2451945617303094
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NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1097276517306147
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Custom Glycosylation of Cells and Proteins Using Cyclic Carbamate-Derivatized Oligosaccharides

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Jmenke
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S2451945617303100
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:CVCL_0006
  
  Curator: @patriciaelyse_
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5562808/
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Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses

1
1. scibot 08 Nov 2017
  
  in Public
  
  THP-1ATCCCat#TIB-202
  
  Curator: @Jmenke
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1931312817302032
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0006
  
  Curator: @chewbeccax
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5473688/
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Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S2451945617300922
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Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis

1
1. scibot 08 Nov 2017
  
  in Public
  
  ATCC TIB-202
  
  Curator: @gabimpine
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S1550413117301584
www.jbc.org www.jbc.org

Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0006
  
  Curator: @Zeljana_Babic
  
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jbc.org/content/292/1/264.long
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Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  THP-1
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S0092867416316853
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A Functional Role for Antibodies in Tuberculosis

1
1. scibot 08 Nov 2017
  
  in Public
  
  Human: THP1
  
  Curator: @chewbeccax
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S0092867416311709
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Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S0092867416317378
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  TIB-202
  
  Curator: @gabimpine
  
  Resource used:
  
  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7360335/
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Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0006
  
  Curator: @gabimpine
  
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  (BCRC Cat# 60430, RRID:CVCL_0006)
  
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sciencedirect.com/science/article/pii/S0092867416312296