1,482 Matching Annotations
  1. Apr 2024
  2. www.pnas.org www.pnas.org
    Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer
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    pnas.org/doi/10.1073/pnas.2319429121
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  4. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Pim kinases triggers a broad antiviral activity by affecting innate immunity and via the PI3K-Akt-mTOR axis the endolysosomal system
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    sciencedirect.com/science/article/pii/S0166354224001001
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    Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses
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    sciencedirect.com/science/article/pii/S0092867424003179
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    Burkholderia thailandensis uses a type VI secretion system to lyse protrusions without triggering host cell responses
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    sciencedirect.com/science/article/pii/S1931312824001136
  7. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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    embopress.org/doi/full/10.1038/s44321-024-00051-z
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022047/
  9. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    sciencedirect.com/science/article/pii/S221112472400439X
  10. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16373
  11. www.mdpi.com www.mdpi.com
    PBMCs as Tool for Identification of Novel Immunotherapy Biomarkers in Lung Cancer
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    mdpi.com/2227-9059/12/4/809
  12. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    DRD1 suppresses cell proliferation and reduces EGFR activation and PD-L1 expression in NSCLC
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13608
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23706
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    Multifunctional host-defense peptides isolated from skin secretions of the banana tree dwelling frog Boana platanera (Hylidae; Hylinae)
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    sciencedirect.com/science/article/pii/S0300908424000701
  16. Mar 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
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    sciencedirect.com/science/article/pii/S2211124724003267
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
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    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
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    sciencedirect.com/science/article/pii/S0944711324001570
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    Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1
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    sciencedirect.com/science/article/pii/S2451945624000886
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
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    An engineering strategy to target activated EGFR with CAR T cells
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    sciencedirect.com/science/article/pii/S2667237524000511
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
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    Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation
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    sciencedirect.com/science/article/pii/S2211124724002730
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    Pneumococcal sialidase promotes bacterial survival by fine-tuning of pneumolysin-mediated membrane disruption
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    sciencedirect.com/science/article/pii/S2211124724002900
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    A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice
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    sciencedirect.com/science/article/pii/S1097276524001382
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926899/
  28. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
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    52.53.155.43/8c6eb3b4d009a4f511a3160975bf106d9641ff9c/1-s2.0-S2950329924000080-main-html.html
  29. www.sciencedirect.com www.sciencedirect.com
    Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2405844024036065
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897164/
  31. Feb 2024
  32. 52.53.155.43 52.53.155.43
    d4-html.html
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    52.53.155.43/f092aa63506937030df3074397696edbfe46ccc6/d4-html.html
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896134/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10894271/
  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17088
  36. aacrjournals.org aacrjournals.org
    Distinct microRNA signature and suppression of ZFP36L1 define ASCL1-positive lung adenocarcinoma
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    aacrjournals.org/mcr/article/22/1/29/731834/Distinct-microRNA-Signature-and-Suppression-of
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870201/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Vα24Jα18 TCR antibody tunes iNKT cell responses to target and kill CD1d-negative tumors in an FcγRII (CD32)-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875981/
  39. 52.53.155.43 52.53.155.43
    The β6 Integrin Negatively Regulates TLR7-Mediated Epithelial Immunity via Autophagy During Influenza A Virus Infection
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    52.53.155.43/a4e24eae360792cb2250e6fbddb4d1d60011b238/2023.08.28.555098v1.full-html.html
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10876858/
  41. www.sciencedirect.com www.sciencedirect.com
    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    sciencedirect.com/science/article/pii/S2211124724001153
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
  43. www.biorxiv.org www.biorxiv.org
    A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
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    biorxiv.org/content/10.1101/2023.12.20.572548v1
  44. www.sciencedirect.com www.sciencedirect.com
    Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer
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    sciencedirect.com/science/article/pii/S2352396424000380
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mieap forms membrane-less organelles involved in cardiolipin metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10845071/
  46. www.sciencedirect.com www.sciencedirect.com
    Targeting TOP2B as a vulnerability in aging and aging-related diseases
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    sciencedirect.com/science/article/pii/S0925443924000292
  47. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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    sciencedirect.com/science/article/pii/S1550413124000056
  48. www.sciencedirect.com www.sciencedirect.com
    Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR
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    sciencedirect.com/science/article/pii/S1534580724000303
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular Targets and Lysine Selectivity of the HERC5 ISG15 Ligase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831901/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831936/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
  52. www.sciencedirect.com www.sciencedirect.com
    SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway
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    sciencedirect.com/science/article/pii/S0304383524000612
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524955/
  54. Jan 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Griseofulvin Radiosensitizes Non-Small Cell Lung Cancer Cells and Activates cGAS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073282/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  57. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of MRPL19 in predicting poor prognosis and promoting the development of lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10413030/
  59. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    cell.com/cell-reports/abstract/S2211-1247(23)01438-9
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10790128/
  61. www.sciencedirect.com www.sciencedirect.com
    Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential
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    sciencedirect.com/science/article/pii/S2666379123006158
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel chimeric antigen receptor-expressing T cells targeting the malignant mesothelioma-specific antigen sialylated HEG1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34843
  63. www.mdpi.com www.mdpi.com
    β-Caryophyllene Inhibits Endothelial Tube Formation by Modulating the Secretome of Hypoxic Lung Cancer Cells—Possible Role of VEGF Downregulation
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    mdpi.com/1422-0067/25/2/810
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simplified Synthesis of Renieramycin T Derivatives to Target Cancer Stem Cells via β-Catenin Proteasomal Degradation in Human Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10744608/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activin A induces apoptosis of human lung adenocarcinoma A549 cells through endoplasmic reticulum stress pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10777458/
  66. www.sciencedirect.com www.sciencedirect.com
    Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19
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    sciencedirect.com/science/article/pii/S2666634023004026
  67. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
  68. www.sciencedirect.com www.sciencedirect.com
    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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    sciencedirect.com/science/article/pii/S0092867423013478
  69. www.thelancet.com www.thelancet.com
    A nanoluciferase SFTSV for rapid screening antivirals and real-time visualization of virus infection in mice
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00510-8/abstract
  70. www.sciencedirect.com www.sciencedirect.com
    PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5
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    sciencedirect.com/science/article/pii/S0166354224000056
  71. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13574
  72. www.sciencedirect.com www.sciencedirect.com
    The pleiotropic enhancer enh9 promotes cell proliferation and migration in non-small cell lung cancer via ERMP1 and PD-L1
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    sciencedirect.com/science/article/pii/S0925443923003812
  73. Dec 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
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    sciencedirect.com/science/article/pii/S2211124723016108
  75. www.embopress.org www.embopress.org
    Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
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    embopress.org/doi/10.1038/s44321-023-00013-x
  76. www.sciencedirect.com www.sciencedirect.com
    The HLA-II immunopeptidome of SARS-CoV-2
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    sciencedirect.com/science/article/pii/S221112472301608X
  77. www.sciencedirect.com www.sciencedirect.com
    Intranasal murine pneumonia virus-vectored SARS-CoV-2 vaccine induces mucosal and serum antibodies in macaques
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    sciencedirect.com/science/article/pii/S2589004223025671
  78. www.sciencedirect.com www.sciencedirect.com
    Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers
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    sciencedirect.com/science/article/pii/S2451945623004221
  79. www.sciencedirect.com www.sciencedirect.com
    iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
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    sciencedirect.com/science/article/pii/S266637912300544X
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  81. www.tandfonline.com www.tandfonline.com
    Identification of putative allosteric inhibitors of BCKDK via virtual screening and biological evaluation
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    tandfonline.com/doi/abs/10.1080/14756366.2023.2290458
  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrative analyses of N6-methyladenosine-associated single-nucleotide polymorphisms (m6A-SNPs) identify tumor suppressor gene AK9 in lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/mc.23669
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10695362/
  84. pubs.acs.org pubs.acs.org
    Selective Tumor Hypoxia Targeting Using M75 Antibody Conjugated Photothermally Active MoOx Nanoparticles
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    pubs.acs.org/doi/full/10.1021/acsomega.3c01934
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
  86. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301722R
  87. Nov 2023
  88. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    sciencedirect.com/science/article/pii/S1097276523008420
  89. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2
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    sciencedirect.com/science/article/pii/S2589004223025269
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair
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