1,227 Matching Annotations
  1. Oct 2022
  2. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA
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    ncbi.nlm.nih.gov/pmc/articles/PMC9563539/
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    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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    sciencedirect.com/science/article/pii/S1550413122004119
  5. pubs.acs.org pubs.acs.org
    Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen
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    pubs.acs.org/doi/full/10.1021/acsptsci.2c00147
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    Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
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    sciencedirect.com/science/article/pii/S2451945622003506
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfments
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    ncbi.nlm.nih.gov/pmc/articles/PMC9519618/
  8. Sep 2022
  9. www.jci.org www.jci.org
    Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
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    jci.org/articles/view/149551
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    Dose-enhancement of MCF 7 cell line radiotherapy using silica-iron oxide nanocomposite
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    sciencedirect.com/science/article/pii/S0006291X22013432
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    A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
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    sciencedirect.com/science/article/pii/S2211124722011901
  12. Aug 2022
  13. 52.53.155.43 52.53.155.43
    149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
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    52.53.155.43/6cce47c11538cf17ab6233a5357637d51d293e1a/149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
  14. 52.53.155.43 52.53.155.43
    cd-21-1671-html.html
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    Drug transporters are implicated in the diffusion of tacrolimus into the T lymphocyte in kidney and liver transplant recipients: Genetic, mRNA, protein expression, and functionality
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    sciencedirect.com/science/article/pii/S1347436722000301
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    Grandiflorenic acid from Wedelia trilobata plant induces apoptosis and autophagy cell death in breast adenocarcinoma (MCF7), lung carcinoma (A549), and hepatocellular carcinoma (HuH7.5) cells lines
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    sciencedirect.com/science/article/pii/S0041010122002409
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Differential Metabolic Signature of Breast Cancer Cellular Response to Olaparib Treatment
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    ncbi.nlm.nih.gov/pmc/articles/PMC9367310/
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    Discovery of compounds that reactivate p53 mutants in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2451945622002756
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357191/
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    CD146 interaction with integrin β1 activates LATS1-YAP signaling and induces radiation-resistance in breast cancer cells
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    sciencedirect.com/science/article/pii/S0304383522003408
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of cytotoxic T lymphocytes by self-differentiated myeloid-derived dendritic cells for killing breast cancer cells expressing folate receptor alpha protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC9342379/
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    Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells
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    sciencedirect.com/science/article/pii/S2666166722004750
  23. Jul 2022
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9329997/
  25. www.nature.com www.nature.com
    Selective footprinting of 40S and 80S ribosome subpopulations (Sel-TCP-seq) to study translation and its control
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    nature.com/articles/s41596-022-00708-4
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    Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness
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    sciencedirect.com/science/article/pii/S2589004222009932
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    Comprehensive metabolome analysis of intracellular metabolites in cultured cells
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    sciencedirect.com/science/article/pii/S2666166722004117
  28. Jun 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9234971/
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    Generation of glycan-specific nanobodies
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    sciencedirect.com/science/article/pii/S2451945622001994
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    sciencedirect.com/science/article/pii/S2589004222007520
  32. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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    sciencedirect.com/science/article/pii/S2666379122001872
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    A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
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    sciencedirect.com/science/article/pii/S2451945622001659
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    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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    sciencedirect.com/science/article/pii/S2211124722006544
  35. aacrjournals.org aacrjournals.org
    Zenocutuzumab, a HER2xHER3 bispecific antibody, is effective therapy for tumors driven by NRG1 gene rearrangements
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    aacrjournals.org/cancerdiscovery/article/12/5/1233/694554/Zenocutuzumab-a-HER2xHER3-Bispecific-Antibody-Is
  36. May 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome
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    ncbi.nlm.nih.gov/pmc/articles/PMC9125938/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR
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    ncbi.nlm.nih.gov/pmc/articles/PMC9113518/
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    DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production
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    sciencedirect.com/science/article/pii/S1097276522003938
  40. aacrjournals.org aacrjournals.org
    Modulation of the estrogen/erbB2 receptors crosstalk by CDK4/6 inhibition triggers sustained senescence in estrogen receptor and erbB2 positive breast cancer
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    aacrjournals.org/clincancerres/article/28/10/2167/694829/Modulation-of-the-Estrogen-erbB2-Receptors-Cross
  41. bmcmedicine.biomedcentral.com bmcmedicine.biomedcentral.com
    Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma
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    bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02373-6
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    Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis
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    sciencedirect.com/science/article/pii/S2211124722005253
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A text-based computational framework for patient -specific modeling for classification of cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC9076893/
  44. www.mdpi.com www.mdpi.com
    Crocodylus porosus Sera a Potential Source to Identify Novel Epigenetic Targets: In Silico Analysis
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    mdpi.com/2306-7381/9/5/210
  45. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
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    tandfonline.com/doi/abs/10.1080/2162402X.2022.2068109
  46. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  47. Apr 2022
  48. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
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    tandfonline.com/doi/abs/10.1080/2162402X.2022.2068109
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and characterization of new tools for detecting poly(ADP-ribose) in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9045816/
  50. www.sciencedirect.com www.sciencedirect.com
    A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway
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    sciencedirect.com/science/article/pii/S258900422200445X
  51. www.sciencedirect.com www.sciencedirect.com
    Lockdown, a selective small-molecule inhibitor of the integrin phosphatase PPM1F, blocks cancer cell invasion
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    sciencedirect.com/science/article/pii/S2451945622001283
  52. elifesciences.org elifesciences.org
    Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads
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    elifesciences.org/articles/73971
  53. aacrjournals.org aacrjournals.org
    MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
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    aacrjournals.org/cancerrescommun/article/2/3/182/694085/MYCMI-7-A-Small-MYC-Binding-Compound-that-Inhibits
  54. aacrjournals.org aacrjournals.org
    Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis
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    aacrjournals.org/cancerres/article/82/7/1321/694048/Hotspot-ESR1-Mutations-Are-Multimodal-and
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B
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    ncbi.nlm.nih.gov/pmc/articles/PMC8954975/
  56. Mar 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors
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    sciencedirect.com/science/article/pii/S2451945622000903
  58. www.sciencedirect.com www.sciencedirect.com
    TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile
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    sciencedirect.com/science/article/pii/S0092867422001817
  59. www.nature.com www.nature.com
    A novel HIF-2α targeted inhibitor suppresses hypoxia-induced breast cancer stemness via SOD2-mtROS-PDI/GPR78-UPRER axis
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    nature.com/articles/s41418-022-00963-8
  60. www.sciencedirect.com www.sciencedirect.com
    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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    sciencedirect.com/science/article/pii/S1550413122000535
  61. www.sciencedirect.com www.sciencedirect.com
    High-throughput characterization of the role of non-B DNA motifs on promoter function
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    sciencedirect.com/science/article/pii/S2666979X22000313
  62. www.sciencedirect.com www.sciencedirect.com
    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    sciencedirect.com/science/article/pii/S2211124722002479
  63. www.sciencedirect.com www.sciencedirect.com
    Ants detect cancer cells through volatile organic compounds
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    sciencedirect.com/science/article/pii/S2589004222002292
  64. link.springer.com link.springer.com
    In Vitro Anti-cancer Effect of Crataegus oxyacantha Berry Extract on Hormone Receptor Positive and Triple Negative Breast Cancers via Regulation of Canonical Wnt Signaling Pathway
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    link.springer.com/article/10.1007/s12010-021-03724-4
  65. www.sciencedirect.com www.sciencedirect.com
    Stem cell differentiation with consistent lineage commitment induced by a flash of ultrafast-laser activation in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2211124722002194
  66. academic.oup.com academic.oup.com
    Unique transcriptomic changes underlie hormonal interactions during mammary histomorphogenesis in female pigs
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    academic.oup.com/endo/article/163/3/bqab256/6464239
  67. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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    aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
  68. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15801
  69. www.sciencedirect.com www.sciencedirect.com
    An optimized protocol for PD-L1 pathological assessment with patient sample deglycosylation to improve correlation with therapeutic response
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    sciencedirect.com/science/article/pii/S2666166722000788
  70. www.sciencedirect.com www.sciencedirect.com
    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124722001759
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    Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
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    sciencedirect.com/science/article/pii/S1097276522001101
  72. Feb 2022
  73. www.sciencedirect.com www.sciencedirect.com
    Systematic illumination of druggable genes in cancer genomes
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    sciencedirect.com/science/article/pii/S2211124722001218
  74. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    sciencedirect.com/science/article/pii/S1097276522000879
  75. www.nature.com www.nature.com
    Global mapping of RNA G-quadruplexes (G4-RNAs) using G4RP-seq
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    nature.com/articles/s41596-021-00671-6
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC8373815/
  77. www.sciencedirect.com www.sciencedirect.com
    An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2666379122000258
  78. www.nature.com www.nature.com
    Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
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    nature.com/articles/s41596-021-00651-w
  79. www.nature.com www.nature.com
    Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting
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    nature.com/articles/s41551-021-00820-y
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast
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    ncbi.nlm.nih.gov/pmc/articles/PMC8349796/
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    An oncogenic enhancer encodes selective selenium dependency in AML
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    sciencedirect.com/science/article/pii/S1934590922000030
  82. Jan 2022
  83. www.sciencedirect.com www.sciencedirect.com
    Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation
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    sciencedirect.com/science/article/pii/S2211124721017964
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Feedback-regulated transcriptional repression of FBXO31 by c-Myc triggers ovarian cancer tumorigenesis
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33854
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
  86. Dec 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
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    sciencedirect.com/science/article/pii/S2211124721016338
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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    sciencedirect.com/science/article/pii/S221112472101634X
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The enhancer rare germline variation rs548071605 contributes to lung cancer development
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    onlinelibrary.wiley.com/doi/10.1002/humu.24310
  90. www.sciencedirect.com www.sciencedirect.com
    Olfactory receptor 5B21 drives breast cancer metastasis
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    sciencedirect.com/science/article/pii/S2589004221014905
  91. www.sciencedirect.com www.sciencedirect.com
    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S1550413121005398
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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    sciencedirect.com/science/article/pii/S2589004221014747
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with oncogenic NRG1 fusions
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    ncbi.nlm.nih.gov/pmc/articles/PMC8172458/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polypeptide-GalNAc-Transferase-13 Shows Prognostic Impact in Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8616257/
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    Changes in the properties of membrane tethers in response to HP1α depletion in MCF7 cells
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    sciencedirect.com/science/article/pii/S0006291X21016028
  96. Nov 2021
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