863 Matching Annotations
  1. Jan 2020
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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
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    sciencedirect.com/science/article/pii/S2211124719311672
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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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    sciencedirect.com/science/article/pii/S0092867419306336
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    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
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    sciencedirect.com/science/article/pii/S1535610819304258
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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    sciencedirect.com/science/article/pii/S0092867419309511
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    sciencedirect.com/science/article/pii/S1934590918305939
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    sciencedirect.com/science/article/pii/S1535610819300406
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    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
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    sciencedirect.com/science/article/pii/S1535610819300984
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    sciencedirect.com/science/article/pii/S2211124719304243
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    sciencedirect.com/science/article/pii/S2211124718320503
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    sciencedirect.com/science/article/pii/S2405471218303958
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    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
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    sciencedirect.com/science/article/pii/S1934590918306015
  14. Nov 2018
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    Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
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    sciencedirect.com/science/article/pii/S1535610818300047
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    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
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    sciencedirect.com/science/article/pii/S0896627318308481
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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S1550413118306284
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    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
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    sciencedirect.com/science/article/pii/S0092867418311796
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    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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    sciencedirect.com/science/article/pii/S1535610818303763
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    ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer
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    sciencedirect.com/science/article/pii/S1097276518306890
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    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
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    sciencedirect.com/science/article/pii/S1934590918303941
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    sciencedirect.com/science/article/pii/S2211124718313494
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    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
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    sciencedirect.com/science/article/pii/S0092867418310298
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    sciencedirect.com/science/article/pii/S1535610818303593
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    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
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    sciencedirect.com/science/article/pii/S1550413118305096
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
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    Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC6134179/
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    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
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    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
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    sciencedirect.com/science/article/pii/S1934590918302844
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    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
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    sciencedirect.com/science/article/pii/S1934590917305118
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    Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus
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    sciencedirect.com/science/article/pii/S1931312818300982
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    An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
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    The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells
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    sciencedirect.com/science/article/pii/S1097276518301084
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    The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S1535610818301739
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    Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC6643283/
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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    sciencedirect.com/science/article/pii/S1535610817305020
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    Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase
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    sciencedirect.com/science/article/pii/S1097276517308456
  40. europepmc.org europepmc.org
    TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.
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    europepmc.org/articles/PMC5438253/
  41. Nov 2017
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    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610817303641
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    Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling
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    sciencedirect.com/science/article/pii/S1535610817304075
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    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
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    sciencedirect.com/science/article/pii/S1934590917303387
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    Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations
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    sciencedirect.com/science/article/pii/S1535610817303495
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    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    sciencedirect.com/science/article/pii/S1535610817303471
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    Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610817303069
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    Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1
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    sciencedirect.com/science/article/pii/S1934590917303193
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    Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
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    sciencedirect.com/science/article/pii/S1934590917300310
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    Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
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    elifesciences.org/articles/26575
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    Stable and Potent Selenomab-Drug Conjugates
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    Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
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    Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling
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    sciencedirect.com/science/article/pii/S1074761317303230
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    Prevention of intestinal ischemia-reperfusion injury in humanized mice
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    sciencedirect.com/science/article/pii/S003960601600163X
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    Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression
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    sciencedirect.com/science/article/pii/S1931312817302494
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    A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis
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    Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation
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    sciencedirect.com/science/article/pii/S1550413117303005
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    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
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    sciencedirect.com/science/article/pii/S1934590917301376
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    BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
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    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells
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    sciencedirect.com/science/article/pii/S1934590917302308
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    Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma
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    Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
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    sciencedirect.com/science/article/pii/S1550413117301705
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    Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
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    Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease
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    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
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    A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
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