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Jul 2021
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Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis

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  DOI: 10.1016/j.celrep.2021.109315
  
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sciencedirect.com/science/article/pii/S2211124721006914
Jun 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

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1. scibot 29 Jun 2021
  
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  DOI: 10.1158/2159-8290.CD-20-1353
  
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cancerdiscovery.aacrjournals.org/content/11/6/1398
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SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B

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1. scibot 26 Jun 2021
  
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  DOI: 10.7554/eLife.67452
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
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Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape

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1. scibot 24 Jun 2021
  
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  DOI: 10.1016/j.immuni.2021.05.019
  
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sciencedirect.com/science/article/pii/S1074761321002259
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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

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1. scibot 24 Jun 2021
  
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  DOI: 10.1016/j.molcel.2021.05.026
  
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sciencedirect.com/science/article/pii/S109727652100410X
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Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

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1. scibot 24 Jun 2021
  
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  DOI: 10.1016/j.cell.2021.05.020
  
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cell.com/cell/fulltext/S0092-8674(21)00650-4
elifesciences.org elifesciences.org

Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

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1. scibot 17 Jun 2021
  
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  DOI: 10.7554/eLife.58342
  
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elifesciences.org/articles/58342
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Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis

1
1. scibot 09 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109229
  
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sciencedirect.com/science/article/pii/S2211124721005805
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PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

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1. scibot 05 Jun 2021
  
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  DOI: 10.7554/eLife.68263
  
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elifesciences.org/articles/68263
May 2021
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The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function

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1. scibot 19 May 2021
  
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  DOI: 10.7554/eLife.61138
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8118657/
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Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity

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1. scibot 13 May 2021
  
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  DOI: 10.7554/eLife.65760
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8104968/
www.nature.com www.nature.com

Loss of Ambra1 promotes melanoma growth and invasion

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1. scibot 12 May 2021
  
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  DOI: 10.1038/s41467-021-22772-2
  
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nature.com/articles/s41467-021-22772-2
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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition

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1. scibot 10 May 2021
  
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  DOI: 10.1038/s41467-021-22643-w
  
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nature.com/articles/s41467-021-22643-w
academic.oup.com academic.oup.com

Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis

1
1. scibot 10 May 2021
  
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  RRID:SCR_015899
  
  DOI: 10.1210/endocr/bqaa210
  
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academic.oup.com/endo/article/162/1/bqaa210/5974117
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Clinical responsiveness to All-trans Retinoic Acid is potentiated by LSD1 inhibition and associated with a quiescent transcriptome in myeloid malignancies

1
1. scibot 10 May 2021
  
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  DOI: 10.1158/1078-0432.CCR-20-4054
  
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clincancerres.aacrjournals.org/content/27/7/1893
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The Oxford Classic Links Epithelial-to-Mesenchymal Transition to Immunosuppression in Poor Prognosis Ovarian Cancers

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1. scibot 10 May 2021
  
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  RRID:SCR_015899
  
  DOI: 10.1158/1078-0432.CCR-20-2782
  
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clincancerres.aacrjournals.org/content/27/5/1570
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Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2021.04.006
  
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sciencedirect.com/science/article/pii/S1934590921001636
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Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

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1. scibot 09 May 2021
  
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  RRID:SCR_015899
  
  DOI: 10.1016/j.stem.2021.01.011
  
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sciencedirect.com/science/article/pii/S1934590921000114
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Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2021.02.015
  
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sciencedirect.com/science/article/pii/S1934590921000655
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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

1
1. scibot 09 May 2021
  
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  RRID:SCR_015899
  
  DOI: 10.1016/j.stem.2020.06.021
  
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sciencedirect.com/science/article/pii/S1934590920302885
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Deficiency of intellectual disability-related gene Brpf1 reduced inhibitory neurotransmission in MGE-derived GABAergic interneurons

1
1. scibot 07 May 2021
  
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  DOI: 10.1093/g3journal/jkab090
  
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academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkab090/6179329
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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.06.003
  
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sciencedirect.com/science/article/pii/S1074761320302338
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A single-cell analysis of the Arabidopsis vegetative shoot apex

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.devcel.2021.02.021
  
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sciencedirect.com/science/article/pii/S1534580721001611
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 06 May 2021
  
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  DOI: 10.1002/1878-0261.12953
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12953
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Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

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1. scibot 01 May 2021
  
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  DOI: 10.7554/eLife.58591
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8064760/
Apr 2021
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Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109032
  
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sciencedirect.com/science/article/pii/S2211124721003466
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The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109039
  
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sciencedirect.com/science/article/pii/S2211124721003557
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Efficient RNA polymerase II pause release requires U2 snRNP function

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1. scibot 26 Apr 2021
  
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  DOI: 10.1016/j.molcel.2021.02.016
  
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sciencedirect.com/science/article/pii/S109727652100126X
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Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis

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1. scibot 22 Apr 2021
  
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  RRID:SCR_015899
  
  DOI: 10.1016/j.ccell.2020.10.012
  
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sciencedirect.com/science/article/pii/S1535610820305432
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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

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1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.06.007
  
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cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
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Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury

1
1. scibot 19 Apr 2021
  
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  DOI: 10.1016/j.neuron.2021.02.018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8068642/
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Immunogenomic Landscape of Hematological Malignancies

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1. scibot 17 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.06.002
  
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sciencedirect.com/science/article/pii/S1535610820302750
www.frontiersin.org www.frontiersin.org

Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor

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1. scibot 17 Apr 2021
  
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  DOI: 10.3389/fnsyn.2021.660718
  
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frontiersin.org/article/10.3389/fnsyn.2021.660718/full
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Messenger RNA capture sequencing of extracellular RNA from human biofluids using a comprehensive set of spike-in controls

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1. scibot 17 Apr 2021
  
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  DOI: 10.1016/j.xpro.2021.100475
  
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sciencedirect.com/science/article/pii/S2666166721001829
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Early stem cell aging in the mature brain

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1. scibot 13 Apr 2021
  
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  DOI: 10.1016/j.stem.2021.03.018
  
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sciencedirect.com/science/article/pii/S1934590921001247
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BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection

1
1. scibot 06 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.03.026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7962543/
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A chromosome-level genome assembly for the Pacific oyster Crassostrea gigas

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1. scibot 06 Apr 2021
  
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  DOI: 10.1093/gigascience/giab020
  
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academic.oup.com/gigascience/article/10/3/giab020/6187865
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Evidence for additive and synergistic action of mammalian enhancers during cell fate determination

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  DOI: 10.7554/eLife.65381
  
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Molecular pathways behind acquired obesity: adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI

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  DOI: 10.1016/j.xcrm.2021.100226
  
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Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium

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  DOI: 10.1186/s12864-021-07528-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8007386/
Mar 2021
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Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery

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1. scibot 21 Mar 2021
  
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  DOI: 10.1016/j.immuni.2021.02.014
  
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Basis of specificity for a conserved and promiscuous chromatin remodeling protein

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  DOI: 10.7554/eLife.64061
  
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The case for using mapped exonic non-duplicate reads when reporting RNA-sequencing depth: examples from pediatric cancer datasets

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  DOI: 10.1093/gigascience/giab011
  
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elifesciences.org elifesciences.org

HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

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  DOI: 10.7554/eLife.61531
  
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Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model

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1. scibot 10 Mar 2021
  
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  DOI: 10.1038/s41598-021-84270-1
  
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EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis

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  DOI: 10.7554/eLife.61070
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7932694/
Sep 2020
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Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

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1. scibot 04 Sep 2020
  
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  RRID: SCR_004463
  
  DOI: 10.1016/j.celrep.2018.09.057
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31502-X
Jan 2020
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A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.neuron.2019.06.011
  
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Nov 2018
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Untitled document

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The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

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Nov 2017
elifesciences.org elifesciences.org

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

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1. scibot 08 Nov 2017
  
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  SCR_004463
  
  Curator: @Zeljana_Babic
  
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elifesciences.org/content/6/e22906