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Nov 2021
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CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

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SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation

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mcr.aacrjournals.org/content/19/11/1831
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Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction

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Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis

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Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins

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Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis

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Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia

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Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription

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Oct 2021
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Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells

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cell.com/cell-reports/fulltext/S2211-1247(21)01347-4
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Glycogen accumulation and phase separation drives liver tumor initiation

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DREAM represses distinct targets by cooperating with different THAP domain proteins

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Comparative cellular analysis of motor cortex in human, marmoset and mouse

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  DOI: 10.1038/s41586-021-03465-8
  
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nature.com/articles/s41586-021-03465-8
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Role of miR-2392 in driving SARS-CoV-2 infection

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PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation

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  DOI: 10.1016/j.celrep.2021.109776
  
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Genomic alterations during the in situ to invasive ductal breast carcinoma transition shaped by the immune system

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ncbi.nlm.nih.gov/pmc/articles/PMC8026652/
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms

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clincancerres.aacrjournals.org/content/27/15/4265
Sep 2021
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Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity

1
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SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape

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  DOI: 10.1016/j.molcel.2021.08.029
  
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The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress

1
1. scibot 16 Sep 2021
  
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Single-cell and single-nucleus RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates, and humans

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1. scibot 14 Sep 2021
  
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Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA

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Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages

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ncbi.nlm.nih.gov/pmc/articles/PMC8412946/
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Single-cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin-driven circadian network

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  DOI: 10.15252/embj.2021108614
  
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embopress.org/doi/full/10.15252/embj.2021108614
Aug 2021
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Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

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Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function

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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation

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Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

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  DOI: 10.1084/jem.20180853
  
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The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells

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  DOI: 10.1158/2159-8290.CD-20-0331
  
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Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity

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  DOI: 10.1016/j.celrep.2021.109494
  
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Lower Airway Dysbiosis Affects Lung Cancer Progression

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Untitled document

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  DOI: 10.1016/j.celrep.2018.09.057
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6205837/
Jul 2021
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Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

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  DOI: 10.1016/j.ccell.2018.01.006
  
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Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice

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  DOI: 10.1016/j.chom.2021.06.014
  
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Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects

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  DOI: 10.1016/j.celrep.2021.109337
  
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Phenotypic Screening Following Transcriptomic Deconvolution to Identify Transcription Factors Mediating Axon Growth Induced by a Kinase Inhibitor - Jeffrey A. Lowell, Nicholas O’Neill, Matt C. Danzi, Hassan Al-Ali, John L. Bixby, Vance P. Lemmon, 2021

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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

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Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis

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LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

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SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B

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Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape

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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

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Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

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Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis

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PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

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The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function

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Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity

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Loss of Ambra1 promotes melanoma growth and invasion

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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition

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Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis

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Clinical responsiveness to All-trans Retinoic Acid is potentiated by LSD1 inhibition and associated with a quiescent transcriptome in myeloid malignancies

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The Oxford Classic Links Epithelial-to-Mesenchymal Transition to Immunosuppression in Poor Prognosis Ovarian Cancers

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Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells

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Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

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Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases

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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

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Deficiency of intellectual disability-related gene Brpf1 reduced inhibitory neurotransmission in MGE-derived GABAergic interneurons

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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis

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A single-cell analysis of the Arabidopsis vegetative shoot apex

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FEBS Press

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Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

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Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome

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The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis

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Efficient RNA polymerase II pause release requires U2 snRNP function

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Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis

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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

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Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury

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Immunogenomic Landscape of Hematological Malignancies

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Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor

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  DOI: 10.3389/fnsyn.2021.660718
  
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Messenger RNA capture sequencing of extracellular RNA from human biofluids using a comprehensive set of spike-in controls

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Early stem cell aging in the mature brain

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BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection

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  DOI: 10.1016/j.cell.2021.03.026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7962543/
academic.oup.com academic.oup.com

A chromosome-level genome assembly for the Pacific oyster Crassostrea gigas

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1. scibot 06 Apr 2021
  
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  RRID:SCR_015899
  
  DOI: 10.1093/gigascience/giab020
  
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academic.oup.com/gigascience/article/10/3/giab020/6187865
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Evidence for additive and synergistic action of mammalian enhancers during cell fate determination

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  DOI: 10.7554/eLife.65381
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8004103/
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Molecular pathways behind acquired obesity: adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI

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  DOI: 10.1016/j.xcrm.2021.100226
  
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Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium

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1. scibot 01 Apr 2021
  
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  DOI: 10.1186/s12864-021-07528-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8007386/
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Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery

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1. scibot 21 Mar 2021
  
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  DOI: 10.1016/j.immuni.2021.02.014
  
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Basis of specificity for a conserved and promiscuous chromatin remodeling protein

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1. scibot 20 Mar 2021
  
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  DOI: 10.7554/eLife.64061
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7968928/
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The case for using mapped exonic non-duplicate reads when reporting RNA-sequencing depth: examples from pediatric cancer datasets

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  DOI: 10.1093/gigascience/giab011
  
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HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

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1. scibot 12 Mar 2021
  
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  DOI: 10.7554/eLife.61531
  
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Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model

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1. scibot 10 Mar 2021
  
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  DOI: 10.1038/s41598-021-84270-1
  
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EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis

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1. scibot 10 Mar 2021
  
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  DOI: 10.7554/eLife.61070
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7932694/
Sep 2020
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Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

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1. scibot 04 Sep 2020
  
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  RRID: SCR_004463
  
  DOI: 10.1016/j.celrep.2018.09.057
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31502-X
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A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.neuron.2019.06.011
  
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sciencedirect.com/science/article/pii/S0896627319305616
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

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1. scibot 05 Nov 2018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5924568/
Nov 2017
elifesciences.org elifesciences.org

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

1
1. scibot 08 Nov 2017
  
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  SCR_004463
  
  Curator: @Zeljana_Babic
  
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elifesciences.org/content/6/e22906

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