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Sep 2020
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Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Effect Complement-Mediated Neurotoxicity

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  DOI: 10.3390/cells9071618
  
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cancerres.aacrjournals.org cancerres.aacrjournals.org

Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation

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  DOI: 10.1158/0008-5472.CAN-19-3247
  
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cancerres.aacrjournals.org/content/80/17/3542
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Herpes Simplex Virus 1-Induced Blood-Brain Barrier Damage Involves Apoptosis Associated With GM130-Mediated Golgi Stress

2
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  DOI: 10.3389/fnmol.2020.00002
  
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  DOI: 10.3389/fnmol.2020.00002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6992570/
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Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis

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  DOI: 10.1016/j.celrep.2020.108014
  
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sciencedirect.com/science/article/pii/S2211124720309992
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mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

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  DOI: 10.7554/eLife.58737
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7467727/
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Mitophagy, Autophagy and Cell Death: The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death

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  DOI: 10.1152/ajpcell.00471.2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6766616/
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FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

1
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  DOI: 10.1016/j.immuni.2020.04.002
  
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sciencedirect.com/science/article/pii/S1074761320301606
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BPS Publications

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  DOI: 10.1111/bph.15010
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15010
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BPS Publications

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  DOI: 10.1111/bph.14983
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14983
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Single-Cell Transcriptome Analysis of Colon Cancer Cell Response to 5-Fluorouracil-Induced DNA Damage

1
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  DOI: 10.1016/j.celrep.2020.108077
  
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sciencedirect.com/science/article/pii/S2211124720310627
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Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense

1
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  DOI: 10.1016/j.cell.2020.03.040
  
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sciencedirect.com/science/article/pii/S0092867420303330
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Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

1
1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.02.002
  
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sciencedirect.com/science/article/pii/S1934590920300552
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NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification

1
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  DOI: 10.1083/jcb.201902164
  
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rupress.org/jcb/article/219/1/e201902164/132733/NCAM-regulates-temporal-specification-of-neural
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EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition

1
1. scibot 08 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1016/j.ccell.2019.12.015
  
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sciencedirect.com/science/article/pii/S1535610819305859
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Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates

1
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  DOI: 10.1016/j.celrep.2020.01.034
  
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sciencedirect.com/science/article/pii/S2211124720300498
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c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly

1
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  RRID:AB_2341188
  
  DOI: 10.1242/dev.185405
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7157583/
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Sirtuin 3 is required for the protective effect of Resveratrol on Manganese‐induced disruption of mitochondrial biogenesis in primary cultured neurons

1
1. scibot 08 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1111/jnc.15095
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15095
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Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression

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1. scibot 08 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1016/j.devcel.2020.01.025
  
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sciencedirect.com/science/article/pii/S1534580720300575
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Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

1
1. scibot 07 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1016/j.celrep.2020.107702
  
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sciencedirect.com/science/article/pii/S2211124720306720
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Transferrin Receptor Is a Specific Ferroptosis Marker

1
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  RRID:AB_2341188
  
  DOI: 10.1016/j.celrep.2020.02.049
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7172030/
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Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis

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  RRID:AB_2341188
  
  DOI: 10.1016/j.celrep.2018.08.057
  
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cell.com/cell-reports/abstract/S2211-1247(18)31344-5
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CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma

1
1. scibot 05 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1016/j.ccell.2020.01.007
  
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sciencedirect.com/science/article/pii/S1535610820300465
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Effects of delayed intraventricular TLR7 agonist administration on long-term neurological outcome following asphyxia in the preterm fetal sheep

1
1. scibot 05 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1038/s41598-020-63770-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7181613/
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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

1
1. scibot 04 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1080/01616412.2020.1735817
  
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tandfonline.com/doi/full/10.1080/01616412.2020.1735817
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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

1
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  RRID:AB_2341188
  
  DOI: 10.1080/01616412.2020.1735817
  
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tandfonline.com/doi/full/10.1080/01616412.2020.1735817
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The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING

1
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  RRID: AB_2341188
  
  DOI: 10.1016/j.celrep.2018.11.097
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31888-6
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The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon Cancer Model

1
1. scibot 04 Sep 2020
  
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  anti-activated caspase-3
  
  DOI: 10.3390/cancers12040853
  
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mdpi.com/2072-6694/12/4/853
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TRPM5-expressing Microvillous Cells Regulate Region-specific Cell Proliferation and Apoptosis during Chemical Exposure

1
1. scibot 04 Sep 2020
  
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  Cleaved caspase-3
  
  DOI: 10.1016/j.neuroscience.2020.03.029
  
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sciencedirect.com/science/article/pii/S0306452220301883
anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com

Mcl1 protein levels and Caspase‐7 executioner protease control axial organizer cells survival

1
1. scibot 04 Sep 2020
  
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  Cleaved Casp3
  
  DOI: 10.1002/dvdy.169
  
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anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.169
cancerres.aacrjournals.org cancerres.aacrjournals.org

A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells

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  Cell Signaling Technology, catalog no. 9661
  
  DOI: 10.1158/0008-5472.CAN-19-0656
  
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cancerres.aacrjournals.org/content/80/3/418
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A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

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  RRID:AB_2341188
  
  DOI: 10.1016/j.chom.2020.05.020
  
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sciencedirect.com/science/article/pii/S1931312820303024
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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

1
1. scibot 03 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1080/01616412.2020.1735817
  
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tandfonline.com/doi/full/10.1080/01616412.2020.1735817
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Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2

1
1. scibot 03 Sep 2020
  
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  RRID:AB_2341188
  
  DOI: 10.1080/01616412.2020.1735817
  
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tandfonline.com/doi/full/10.1080/01616412.2020.1735817
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Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source | American Journal of Physiology-Gastrointestinal and Liver Physiology

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  AB_2341188
  
  DOI: 10.1152/ajpgi.00387.2019
  
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Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis | American Journal of Physiology-Lung Cellular and Molecular Physiology

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  RRID:AB_2341188
  
  DOI: 10.1152/ajplung.00069.2019
  
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IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway

1
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  rabbit anti-cleaved caspase 3
  
  DOI: 10.3390/cells9010147
  
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mdpi.com/2073-4409/9/1/147
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival

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  Cleaved Caspase-3
  
  DOI: 10.1016/j.celrep.2020.108092
  
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An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress

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  rabbit anti-cleaved-caspase 3
  
  DOI: 10.1016/j.nbd.2020.105050
  
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dev.biologists.org dev.biologists.org

Neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and brain size in Xenopus embryos

1
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  cleaved caspase 3
  
  DOI: 10.1242/dev.189290
  
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Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT

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  anti–cleaved caspase-3
  
  DOI: 10.1172/JCI128994
  
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SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

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  RRID:AB_2341188
  
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Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal

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  RRID:AB_2341188
  
  DOI: 10.1016/j.celrep.2019.12.100
  
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Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

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  RRID:AB_2341188
  
  DOI: 10.7554/eLife.53367
  
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Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

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  RRID:AB_2341188
  
  DOI: 10.1016/j.xcrm.2020.100002
  
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Aug 2020
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The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress

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1. scibot 26 Aug 2020
  
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  RRID:AB_234118
  
  DOI: 10.1016/j.celrep.2020.107846
  
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Jan 2020
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Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons

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  DOI: 10.1016/j.celrep.2019.09.075
  
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Delayed Effects of Acute Reperfusion on Vascular Remodeling and Late-Phase Functional Recovery After Stroke

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  RRID:AB_2341188
  
  DOI: 10.3389/fnins.2019.00767
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6664024/
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Glial Phagocytic Receptors Promote Neuronal Loss in Adult Drosophila Brain

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  RRID:AB_2341188
  
  DOI: 10.1016/j.celrep.2019.09.086
  
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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

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  RRID:AB_2341188
  
  DOI: 10.1016/j.ccell.2019.05.003
  
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Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes

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  AB_2341188
  
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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

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  RRID:AB_2341188
  
  DOI: 10.1016/j.ccell.2019.05.001
  
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

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  DOI: 10.1016/j.molcel.2019.06.043
  
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Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation

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  RRID:AB_2341188
  
  DOI: 10.1016/j.devcel.2019.05.032
  
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The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

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  DOI: 10.1016/j.cell.2019.05.035
  
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VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance

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  DOI: 10.1016/j.celrep.2019.07.072
  
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let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7

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  RRID:AB_2341188
  
  DOI: 10.1016/j.celrep.2019.11.029
  
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A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

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  DOI: 10.7554/eLife.47097
  
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Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development

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  DOI: 10.1016/j.celrep.2019.08.078
  
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Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development

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  DOI: 10.1016/j.cub.2019.07.061
  
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miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer

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cell.com/cell-reports/fulltext/S2211-1247(19)31576-1
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Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

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  DOI: 10.7554/eLife.45303
  
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Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ

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  DOI: 10.1016/j.immuni.2019.06.017
  
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Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain

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  DOI: 10.1016/j.cub.2019.08.003
  
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The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes

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Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelination

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  DOI: 10.1002/glia.23646
  
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GABAergic Restriction of Network Dynamics Regulates Interneuron Survival in the Developing Cortex

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  DOI: 10.1016/j.neuron.2019.10.008
  
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Microglia mediate HIV-1 gp120-induced synaptic degeneration in spinal pain neural circuits

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Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses

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DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration

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Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms

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Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease

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Early-generated interneurons regulate neuronal circuit formation during early postnatal development

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The DNA Repair Nuclease MRE11A Functions as a Mitochondrial Protector and Prevents T Cell Pyroptosis and Tissue Inflammation

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MicroRNA-25-5p counteracts oxidized LDL-induced pathological changes by targeting neuronal growth regulator 1 (NEGR1) in human brain micro-vessel endothelial cells

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SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation

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Neuronal Ca2+‐dependent activator protein 1 (NCDAP1) induces neuronal cell death by activating p53 pathway following traumatic brain injury

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The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression

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The Gypsy Endogenous Retrovirus Drives Non-Cell-Autonomous Propagation in a Drosophila TDP-43 Model of Neurodegeneration

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Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

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Donepezil‐induced oligodendrocyte differentiation is mediated through estrogen receptors

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Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

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A dual‐functional memantine nitrate MN‐08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid hemorrhage models

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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

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A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas

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Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents

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Early treatment with C1 esterase inhibitor improves weight but not memory deficits in a rat model of status epilepticus

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N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

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Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis

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Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

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Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover

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A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

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Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria

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Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation

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Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer

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AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

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Screening the expression of several miRNAs from TaqMan Low Density Array in traumatic brain injury: miR‐219a‐5p regulates neuronal apoptosis by modulating CCNA2 and CACUL1

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Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function

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Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors

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IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer

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Sox17 Regulates a Program of Oligodendrocyte Progenitor Cell Expansion and Differentiation during Development and Repair

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Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity

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Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets

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Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration

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Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse

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N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis

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Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP‐induced Parkinson's disease in mice

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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

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Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis

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A Tissue- and Temporal-Specific Autophagic Switch Controls Drosophila Pre-metamorphic Nutritional Checkpoints

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Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis

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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

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Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

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Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity

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Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

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Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors

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Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep

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Sex differences in neonatal mouse brain injury after hypoxia ischemia and adaptaquin treatment

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Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration

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WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

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3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival

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Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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Survival of Naïve T Cells Requires the Expression of Let-7 miRNAs

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CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

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Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms

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Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

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Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain

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High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers

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IGFBP-3 Induced by Ribotoxic Stress Traffics From the Endoplasmic Reticulum to the Nucleus in Mammary Epithelial Cells

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Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

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Intestine-Specific Overexpression of LDLR Enhances Cholesterol Excretion and Induces Metabolic Changes in Male Mice

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Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play

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MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer

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Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models

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Viral vector‐mediated Cre recombinase expression in substantia nigra induces lesions of the nigrostriatal pathway associated with perturbations of dopamine‐related behaviors and hallmarks of programmed cell death

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Chicken embryos share mammalian patterns of apoptosis in the posterior placodal area

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Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion

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Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation

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Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity

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iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications

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NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus

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The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression

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Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

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Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory

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Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

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Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses

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A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in a spider

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Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification

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Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells

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Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

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Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease

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Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues

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The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells

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RANKL/RANK control Brca1 mutation-driven mammary tumors

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Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

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A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer

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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

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Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import

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Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease

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PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ

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Radial WNT5A-Guided Post-mitotic Filopodial Pathfinding Is Critical for Midgut Tube Elongation

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Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

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Type 2 Diabetes Leads to Axon Initial Segment Shortening in db/db Mice

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