1,697 Matching Annotations
  1. Nov 2018
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    Immunomimetic Designer Cells Protect Mice from MRSA Infection
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    Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
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    sciencedirect.com/science/article/pii/S1931312818302634
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    Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2
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    sciencedirect.com/science/article/pii/S1097276518303927
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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    Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling
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    An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3
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    Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread
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    GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion
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    The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
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    elifesciences.org/articles/31879
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    The Cellosaurus, a Cell-Line Knowledge Resource
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    SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription
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    The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells
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    Cell-Autonomous Regulation of Dendrite Self-Avoidance by the Wnt Secretory Factor MIG-14/Wntless
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    Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
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    Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter
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    TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer
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    SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform
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    Quantitative super-resolution single molecule microscopy dataset of YFP-tagged growth factor receptors
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    The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling
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    Decoding a Salmonella Typhi Regulatory Network that Controls Typhoid Toxin Expression within Human Cells
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    A Method for the Acute and Rapid Degradation of Endogenous Proteins
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    Regulation of m6A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline
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    Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins
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    elifesciences.org/articles/27860
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    Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP.
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    Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.
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    IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.
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    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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  35. Nov 2017
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    Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17
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    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
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    New tools for “hot-wiring” clathrin-mediated endocytosis with temporal and spatial precision
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    Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
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    Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion
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    Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells
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    Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells
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    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
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    The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation
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    Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism
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    Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer’s Disease
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    Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening
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    Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
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    TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
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    A novel c‐Src recruitment pathway from the cytosol to focal adhesions
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    The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover
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    Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics
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    Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
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    SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport
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    RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6
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    SLERT Regulates DDX21 Rings Associated with Pol I Transcription
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    A Tunable Brake for HECT Ubiquitin Ligases
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    Efficient, Selective Removal of Human Pluripotent Stem Cells via Ecto-Alkaline Phosphatase-Mediated Aggregation of Synthetic Peptides
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    DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
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    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
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    MLL/WDR5 Complex Regulates Kif2A Localization to Ensure Chromosome Congression and Proper Spindle Assembly during Mitosis
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    Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib
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    Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection
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    Sensing Self and Foreign Circular RNAs by Intron Identity
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    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
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    LTR-Retrotransposon Control by tRNA-Derived Small RNAs
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    Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5
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    Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex
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    Pimozide reduces toxic forms of tau in TauC3 mice via AMPK‐mediated autophagy
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    The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms
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    Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases
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    MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
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    Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores
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    How to Increase Brightness of Near-Infrared Fluorescent Proteins in Mammalian Cells
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    Apoptosis and Compensatory Proliferation Signaling Are Coupled by CrkI-Containing Microvesicles
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    RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice
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    A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis
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    p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway
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    elifesciences.org/content/6/e22207
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    YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
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    elifesciences.org/content/6/e22416
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    Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy
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    Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor
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    Imaging ERK and PKA Activation in Single Dendritic Spines during Structural Plasticity
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    Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis
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    Bassoon Controls Presynaptic Autophagy through Atg5
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    A Metabolic Function for Phospholipid and Histone Methylation
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    Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk
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    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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    Mesenchyme Homeobox 2 Enhances Migration of Endothelial Colony Forming Cells Exposed to Intrauterine Diabetes Mellitus
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    onlinelibrary.wiley.com/doi/10.1002/jcp.25734/full
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    A conformational switch regulates the ubiquitin ligase HUWE1
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    Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
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    sciencedirect.com/science/article/pii/S009286741630914X
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact
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    ncbi.nlm.nih.gov/pmc/articles/PMC5173324/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5130294/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC5016092/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC5127641/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes
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    ncbi.nlm.nih.gov/pmc/articles/PMC5021521/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC4985285/