776 Matching Annotations
  1. Dec 2022
  2. link.springer.com link.springer.com
    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
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    1. scibot 20 Dec 2022
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      DOI: 10.1007/s00018-022-04638-y

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  3. www.sciencedirect.com www.sciencedirect.com
    The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease
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    1. scibot 18 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722016916
  4. www.science.org www.science.org
    Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension
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    1. scibot 13 Dec 2022
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    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
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  6. aacrjournals.org aacrjournals.org
    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
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    1. scibot 03 Dec 2022
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      DOI: 10.1158/2159-8290.CD-22-0287

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    aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Morusin Protected Ruminal Epithelial Cells against Lipopolysaccharide-Induced Inflammation through Inhibiting EGFR-AKT/NF-κB Signaling and Improving Barrier Functions
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      DOI: 10.3390/ijms232214428

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  8. Nov 2022
  9. www.sciencedirect.com www.sciencedirect.com
    Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
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    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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    1. scibot 22 Nov 2022
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    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
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    BPS Publications
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  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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    1. scibot 19 Nov 2022
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    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
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  15. academic.oup.com academic.oup.com
    mTOR inhibition decreases angiotensin II-induced steroidogenesis in HAC15 human adrenocortical carcinoma cells
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    1. scibot 19 Nov 2022
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  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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  17. www.researchsquare.com www.researchsquare.com
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      DOI: 10.21203/rs.3.rs-658360/v1

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  18. www.nature.com www.nature.com
    DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts
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  19. www.sciencedirect.com www.sciencedirect.com
    Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect
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  21. academic.oup.com academic.oup.com
    Granulosa Cell Dysfunction Is Associated with Diminished Ovarian Response in FMR1 Premutation Carriers
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      DOI: 10.1210/clinem/dgac536

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  22. Oct 2022
  23. academic.oup.com academic.oup.com
    Mineralocorticoid receptors mediates diet - induced lipid infiltration of skeletal muscle and insulin resistance
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    1. scibot 29 Oct 2022
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      DOI: 10.1210/endocr/bqac145

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    Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein
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    1. scibot 28 Oct 2022
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    sciencedirect.com/science/article/pii/S2451945622003609
  25. elifesciences.org elifesciences.org
    Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury
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      DOI: 10.7554/eLife.78540

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    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
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  27. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
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    KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice
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  29. www.sciencedirect.com www.sciencedirect.com
    E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
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  30. journals.lww.com journals.lww.com
    Poly-L-ornithine blocks the inhibitory effects of... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.353493

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  31. Sep 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
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      DOI: 10.3389/fimmu.2022.931087

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    Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379122001914
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    Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis
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  35. www.mdpi.com www.mdpi.com
    Stimulation of Akt Phosphorylation and Glucose Transport by Metalloporphyrins with Peroxynitrite Decomposition Catalytic Activity
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      DOI: 10.3390/catal12080849

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  36. www.sciencedirect.com www.sciencedirect.com
    SerpinB3 drives cancer stem cell survival in glioblastoma
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  37. www.nature.com www.nature.com
    Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
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      DOI: 10.1038/s42003-022-03942-4

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
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  40. Aug 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia
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      DOI: 10.1016/j.heliyon.2022.e10371

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    sciencedirect.com/science/article/pii/S2405844022016590
  42. www.science.org www.science.org
    Functional and biological heterogeneity of KRASQ61 mutations
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      DOI: 10.1126/scisignal.abn2694

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    science.org/doi/10.1126/scisignal.abn2694
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    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
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      DOI: 10.7554/eLife.80725

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    ncbi.nlm.nih.gov/pmc/articles/PMC9371604/
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    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
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  88. aacrjournals.org aacrjournals.org
    δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice
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  89. Mar 2022
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice
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  91. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons
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  95. www.sciencedirect.com www.sciencedirect.com
    Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma
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    Interleukin-6 mimics insulin-dependent cellular distribution of some cytoskeletal proteins and Glut4 transporter without effect on glucose uptake in 3T3-L1 adipocytes
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  97. www.sciencedirect.com www.sciencedirect.com
    Creatine transport and creatine kinase activity is required for CD8+ T cell immunity
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    Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
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  99. Feb 2022
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    Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2
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    Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion
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  103. www.sciencedirect.com www.sciencedirect.com
    Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance
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    BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer
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    Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions
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    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
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    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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    The early reduction of left ventricular mass after sleeve gastrectomy depends on the fall of branched-chain amino acid circulating levels
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
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    Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis
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  111. Jan 2022
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2
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    Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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  117. Dec 2021
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    The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  125. Nov 2021
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    CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development
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