627 Matching Annotations
  1. Feb 2022
  2. academic.oup.com academic.oup.com
    Growth hormone-induced STAT5B regulates Star gene expression through a cooperation with cJUN in mouse MA-10 Leydig cells
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    1. scibot 01 Feb 2022
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      DOI: 10.1210/endocr/bqab267

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    academic.oup.com/endo/article/163/2/bqab267/6490116
  3. Jan 2022
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    Purification of functional Plasmodium falciparum tubulin allows for the identification of parasite-specific microtubule inhibitors
    1
    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.cub.2021.12.049

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    sciencedirect.com/science/article/pii/S096098222101736X
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    SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport
    1
    1. scibot 26 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.018

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    sciencedirect.com/science/article/pii/S1534580721010388
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    Compartmentalized control of Cdk1 drives mitotic spindle assembly
    1
    1. scibot 26 Jan 2022
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      DOI: 10.1016/j.celrep.2022.110305

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    sciencedirect.com/science/article/pii/S2211124722000171
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    Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis
    1
    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.neuron.2021.12.019

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    sciencedirect.com/science/article/pii/S0896627321010369
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    Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
    1
    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110213

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    sciencedirect.com/science/article/pii/S2211124721017174
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    Coordinated post-transcriptional control of oncogene-induced senescence by UNR/CSDE1
    1
    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110211

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    sciencedirect.com/science/article/pii/S2211124721017150
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    The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1186/s40478-021-01285-5

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    link.springer.com/article/10.1186/s40478-021-01285-5
  11. Dec 2021
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    Assessing kinetics and recruitment of DNA repair factors using high content screens
    1
    1. scibot 29 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110176

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    sciencedirect.com/science/article/pii/S2211124721016764
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    Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
    1
    1. scibot 21 Dec 2021
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      DOI: 10.1016/j.jbc.2021.101508

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    sciencedirect.com/science/article/pii/S0021925821013181
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    Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos
    1
    1. scibot 17 Dec 2021
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      DOI: 10.1016/j.devcel.2021.11.021

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    sciencedirect.com/science/article/pii/S153458072100945X
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    TAOK2 is an ER-localized kinase that catalyzes the dynamic tethering of ER to microtubules
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.devcel.2021.11.015

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    sciencedirect.com/science/article/pii/S1534580721009394
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.isci.2021.103503

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    sciencedirect.com/science/article/pii/S2589004221014747
  17. Nov 2021
  18. www.sciencedirect.com www.sciencedirect.com
    Developmental defects in Huntington’s disease show that axonal growth and microtubule reorganization require NUMA1
    1
    1. scibot 18 Nov 2021
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      DOI: 10.1016/j.neuron.2021.10.033

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    sciencedirect.com/science/article/pii/S0896627321008631
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
    1
    1. scibot 11 Nov 2021
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      DOI: 10.1016/j.stem.2021.10.009

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    sciencedirect.com/science/article/pii/S1934590921004215
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    Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8
    1
    1. scibot 10 Nov 2021
      RRID:AB_477593

      DOI: 10.1016/j.devcel.2021.10.017

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    sciencedirect.com/science/article/pii/S1534580721008480
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    Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes
    1
    1. scibot 05 Nov 2021
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      DOI: 10.1016/j.cub.2021.10.022

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    sciencedirect.com/science/article/pii/S0960982221014111
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    Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
    1
    1. scibot 03 Nov 2021
      RRID:AB_477593

      DOI: 10.1016/j.celrep.2021.109924

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    sciencedirect.com/science/article/pii/S2211124721013978
  23. Oct 2021
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope
    1
    1. scibot 23 Oct 2021
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      DOI: 10.7554/eLife.65672

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    ncbi.nlm.nih.gov/pmc/articles/PMC8523159/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition
    1
    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.isci.2021.103180

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    ncbi.nlm.nih.gov/pmc/articles/PMC8506969/
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    Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos
    1
    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109851

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    sciencedirect.com/science/article/pii/S2211124721013188
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    Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription
    1
    1. scibot 13 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109803

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    sciencedirect.com/science/article/pii/S2211124721012638
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complex species and strain ecology of the vaginal microbiome from pregnancy to postpartum and association with preterm birth
    1
    1. scibot 08 Oct 2021
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      DOI: 10.1016/j.medj.2021.06.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC8491999/
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    Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis
    1
    1. scibot 07 Oct 2021
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      DOI: 10.1016/j.isci.2021.103151

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    sciencedirect.com/science/article/pii/S2589004221011196
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    The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment
    1
    1. scibot 06 Oct 2021
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      DOI: 10.1016/j.isci.2021.103112

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    sciencedirect.com/science/article/pii/S2589004221010804
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles
    1
    1. scibot 04 Oct 2021
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      DOI: 10.1074/jbc.RA120.014791

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    ncbi.nlm.nih.gov/pmc/articles/PMC7535905/
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    Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle
    1
    1. scibot 01 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109753

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    sciencedirect.com/science/article/pii/S2211124721012079
  33. Sep 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
    1
    1. scibot 28 Sep 2021
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      DOI: 10.7554/eLife.65484

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    ncbi.nlm.nih.gov/pmc/articles/PMC8457837/
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    Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion
    1
    1. scibot 24 Sep 2021
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      DOI: 10.1016/j.devcel.2021.09.007

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    sciencedirect.com/science/article/pii/S1534580721007255
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9
    1
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      DOI: 10.21769/BioProtoc.2222

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    ncbi.nlm.nih.gov/pmc/articles/PMC8410427/
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    Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion
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      DOI: 10.1016/j.cell.2021.08.035

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    sciencedirect.com/science/article/pii/S0092867421010461
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Overexpression of α-synuclein inhibits mitochondrial Ca2+ trafficking between the endoplasmic reticulum and mitochondria through MAMs by altering the GRP75–IP3R interaction
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      DOI: 10.1002/jnr.24952

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24952
  39. elifesciences.org elifesciences.org
    Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization
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      DOI: 10.7554/eLife.68918

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    elifesciences.org/articles/68918
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    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
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      DOI: 10.1016/j.celrep.2021.109673

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    sciencedirect.com/science/article/pii/S2211124721011177
  41. Aug 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes
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      DOI: 10.7554/eLife.70588

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    ncbi.nlm.nih.gov/pmc/articles/PMC8370769/
  43. academic.oup.com academic.oup.com
    Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1
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      DOI: 10.1093/narcan/zcab033

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    academic.oup.com/narcancer/article/3/3/zcab033/6352433
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    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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      DOI: 10.1016/j.ccell.2021.07.006

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    sciencedirect.com/science/article/pii/S1535610821003834
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    Cytohesin-2 mediates group I metabotropic glutamate receptor-dependent mechanical allodynia through the activation of ADP ribosylation factor 6 in the spinal cord
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      DOI: 10.1016/j.nbd.2021.105466

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    sciencedirect.com/science/article/pii/S0969996121002151
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
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      DOI: 10.1016/j.isci.2021.102845

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    ncbi.nlm.nih.gov/pmc/articles/PMC8333345/
  47. elifesciences.org elifesciences.org
    Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT/CTNNB1 signaling dynamics
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      DOI: 10.7554/eLife.66440

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  92. www.nature.com www.nature.com
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  93. www.frontiersin.org www.frontiersin.org
    Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion
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    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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    The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy
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    Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm
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  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate
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    Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21
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    Astrocytes contribute to Aβ‐induced blood–brain barrier damage through activation of endothelial MMP9
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    Retinoic acid receptor‐related orphan receptor RORα regulates differentiation and survival of keratinocytes during hypoxia
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    Histamine H1 and H3 receptor activation increases the expression of Glucose Transporter 1 (GLUT-1) in rat cerebro-cortical astrocytes in primary culture
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    De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones
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  114. rupress.org rupress.org
    TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity
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    Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation
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    miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila
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    Knock-Out of Tenascin-C Ameliorates Ischemia-Induced Rod-Photoreceptor Degeneration and Retinal Dysfunction
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    Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model
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    Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
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    Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue
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    Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties
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  125. May 2021
  126. elifesciences.org elifesciences.org
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    OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21
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      Anti-α-tubulin (Mouse monoclonal)

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    A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression
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    Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
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    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
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    The Vps52 subunit of the GARP and EARP complexes is a novel Arf6-interacting protein that negatively regulates neurite outgrowth of hippocampal neurons
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    Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs
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    Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283
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    Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes
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    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage
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