837 Matching Annotations
  1. Oct 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Exocyst complex mediates recycling of internal cilia
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    sciencedirect.com/science/article/pii/S0960982221013233
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    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
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      DOI: 10.1016/j.celrep.2021.109856

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    sciencedirect.com/science/article/pii/S2211124721013231
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      DOI: 10.1111/bph.15653

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15653
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    Alpha-Lipoic Acid Prevents Side Effects of Therapeutic Nanosilver without Compromising Cytotoxicity in Experimental Pancreatic Cancer
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      DOI: 10.3390/cancers13194770

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    ncbi.nlm.nih.gov/pmc/articles/PMC8507678/
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    Interleukin-6 Promotes Microtubule Stability in Axons via Stat3 Protein-Protein Interactions
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    sciencedirect.com/science/article/pii/S2589004221011093
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    Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice
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    sciencedirect.com/science/article/pii/S221112472101295X
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    IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation
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      DOI: 10.1016/j.immuni.2021.09.010

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    sciencedirect.com/science/article/pii/S1074761321003952
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    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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    sciencedirect.com/science/article/pii/S1097276521007504
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    Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis
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    sciencedirect.com/science/article/pii/S2589004221011196
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    DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing
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    sciencedirect.com/science/article/pii/S1550413121004277
  12. Sep 2021
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    Effect of Three NR3C1 mutations in Pathogenesis of Pituitary ACTH Adenoma
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      DOI: 10.1210/endocr/bqab167

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    academic.oup.com/endo/article/162/11/bqab167/6357044
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    The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
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    1. scibot 22 Sep 2021
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      DOI: 10.7554/eLife.68843

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    ncbi.nlm.nih.gov/pmc/articles/PMC8445623/
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    Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion
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      DOI: 10.1016/j.cell.2021.08.035

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    sciencedirect.com/science/article/pii/S0092867421010461
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    Reading ADP-ribosylation signaling using chemical biology and interaction proteomics
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    sciencedirect.com/science/article/pii/S1097276521007176
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    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
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    1. scibot 21 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109689

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    sciencedirect.com/science/article/pii/S2211124721011360
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    Denaturing cross-linking immunoprecipitation to identify footprints for RNA-binding proteins
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    sciencedirect.com/science/article/pii/S2666166721005256
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    SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages
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    sciencedirect.com/science/article/pii/S2211124721011062
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    Transcriptional control of brain tumor stem cells by a carbohydrate binding protein
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      DOI: 10.1016/j.celrep.2021.109647

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    sciencedirect.com/science/article/pii/S2211124721010901
  21. Aug 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An AAV-based, room-temperature stable, single dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates
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    1. scibot 27 Aug 2021
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      DOI: 10.1016/j.chom.2021.08.002

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    ncbi.nlm.nih.gov/pmc/articles/PMC8346325/
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    Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation
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    sciencedirect.com/science/article/pii/S2211124721009992
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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      DOI: 10.1016/j.celrep.2021.109526

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    sciencedirect.com/science/article/pii/S2211124721009578
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    Shigella OspC3 suppresses murine cytosolic LPS sensing
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    ncbi.nlm.nih.gov/pmc/articles/PMC8361271/
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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    sciencedirect.com/science/article/pii/S0896627321005067
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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    sciencedirect.com/science/article/pii/S2211124721009426
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    A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies
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    sciencedirect.com/science/article/pii/S1097276521005906
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    A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength
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    sciencedirect.com/science/article/pii/S2211124721008901
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    ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
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    sciencedirect.com/science/article/pii/S0092867421008291
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    Tissue Specific Ablation of ACSL4 Results in Disturbed Steroidogenesis
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    academic.oup.com/endo/article/160/11/2517/5554112
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    Modulation of LIN28B/Let-7 signaling by propranolol contributes to infantile hemangioma involution
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    ncbi.nlm.nih.gov/pmc/articles/PMC5970092/
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      DOI: 10.1210/jc.2018-01573

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    academic.oup.com/jcem/article/104/6/2041/5239680
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      DOI: 10.3390/ijms20051178

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    mdpi.com/1422-0067/20/5/1178
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      DOI: 10.1111/jnc.14029

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14029
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    ncbi.nlm.nih.gov/pmc/articles/PMC5659665/
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    ncbi.nlm.nih.gov/pmc/articles/PMC5761600/
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    ncbi.nlm.nih.gov/pmc/articles/PMC5773094/
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      DOI: 10.7554/eLife.22871

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    sciencedirect.com/science/article/pii/S2211124718316462
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    sciencedirect.com/science/article/pii/S2211124718315316
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    Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib
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      DOI: 10.1016/j.ccell.2017.11.006

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    sciencedirect.com/science/article/pii/S1535610817305093
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    ncbi.nlm.nih.gov/pmc/articles/PMC5756609/
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    Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex
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    RS9, a novel Nrf2 activator, attenuates light‐induced death of cells of photoreceptor cells and Müller glia cells
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    Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life
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    Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution | Arteriosclerosis, Thrombosis, and Vascular Biology
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    TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
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    Silenced ZNF154 Is Associated with Longer Survival in Resectable Pancreatic Cancer
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  64. www.nature.com www.nature.com
    Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK
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      GAPDH

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  66. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
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    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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    Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport
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    Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA
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    Human Breast Cancer Xenograft Model Implicates Peroxisome Proliferator–activated Receptor Signaling as Driver of Cancer-induced Muscle Fatigue
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    BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
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    Fibroblast growth factor 2 regulates activity and gene expression of human post‐mitotic excitatory neurons
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  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    BMP Signaling Mediated by BMPR1A in Osteoclasts Negatively Regulates Osteoblast Mineralization Through Suppression of Cx43
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  85. www.sciencedirect.com www.sciencedirect.com
    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
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    Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission
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      2118

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    The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease
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    Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
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  173. www.sciencedirect.com www.sciencedirect.com
    AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ
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  174. www.sciencedirect.com www.sciencedirect.com
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
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  175. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy
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      GAPDH

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  176. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
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  177. Jan 2021
  178. www.sciencedirect.com www.sciencedirect.com
    Proton-activated chloride channel PAC regulates endosomal acidification and transferrin receptor-mediated endocytosis
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    NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
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    ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
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      DOI: 10.1016/j.celrep.2020.108594

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    DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks
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      DOI: 10.1016/j.celrep.2020.108569

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  183. Dec 2020
  184. academic.oup.com academic.oup.com
    A ubiquitin switch controls autocatalytic inactivation of the DNA–protein crosslink repair protease SPRTN
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      anti-GAPDH

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  185. www.sciencedirect.com www.sciencedirect.com
    CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci
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    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
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      RRID:AB_561053

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    Weak acids induce PGE 2 production in human oesophageal cells: novel mechanisms underlying GERD symptoms
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    A Hemidesmosome-to-Cytoplasm Translocation of Small Heat Shock Proteins Provides Immediate Protection against Heat Stress
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    Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation
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  190. Nov 2020
  191. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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    De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment
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      rabbit polyclonal anti-GAPDH

      DOI: 10.1016/j.ajhg.2020.10.012

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  194. www.frontiersin.org www.frontiersin.org
    Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway
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      DOI: 10.3389/fendo.2020.579161

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  195. www.cell.com www.cell.com
    A Ca2+-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration
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      DOI: 10.1016/j.cub.2020.09.043

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
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  197. Oct 2020
  198. www.sciencedirect.com www.sciencedirect.com
    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
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      DOI: 10.1016/j.chembiol.2020.10.001

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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain
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      RRID:AB_1031003

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    Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry
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      RRID:AB_561053

      DOI: 10.1016/j.celrep.2020.108292

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  201. elifesciences.org elifesciences.org
    Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila
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      DOI: 10.7554/eLife.57395

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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation
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    Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
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      RRID:AB_561053

      DOI: 10.1016/j.cellsig.2020.109735

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  204. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of the CARD8 Inflammasome Requires a Disordered Region
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      RRID:AB_561053

      DOI: 10.1016/j.celrep.2020.108264

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  205. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma
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      glyceraldehyde‐3‐phosphate dehydrogenase

      DOI: 10.1002/cac2.12103

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  206. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
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      DOI: 10.1016/j.cell.2020.09.020

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    Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae
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      DOI: 10.1016/j.jss.2020.08.071

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    Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
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      RRID:AB_561053

      DOI: 10.1016/j.redox.2020.101742

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    Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation
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      DOI: 10.1016/j.cell.2020.09.002

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  210. Sep 2020
  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity
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      DOI: 10.1016/j.ebiom.2020.102996

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    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
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    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
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      DOI: 10.1016/j.molcel.2019.12.022

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    FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
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