326 Matching Annotations
  1. Jun 2021
  2. www.sciencedirect.com www.sciencedirect.com
    A C-circle assay for detection of alternative lengthening of telomere activity in FFPE tissue
    1
    1. scibot 02 Jun 2021
      RRID:SCR_014210

      DOI: 10.1016/j.xpro.2021.100569

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    sciencedirect.com/science/article/pii/S2666166721002768
  3. May 2021
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion
    1
    1. scibot 12 May 2021
      RRID:SCR_014210

      DOI: 10.7554/eLife.64474

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    ncbi.nlm.nih.gov/pmc/articles/PMC8096436/
  5. www.sciencedirect.com www.sciencedirect.com
    Angelica sinensis polysaccharide attenuates CCl4-induced liver fibrosis via the IL-22/STAT3 pathway
    1
    1. scibot 06 May 2021
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      DOI: 10.1016/j.ijbiomac.2020.06.166

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    sciencedirect.com/science/article/pii/S0141813020336072
  6. www.nature.com www.nature.com
    Dissociation of disease onset, progression and sex differences from androgen receptor levels in a mouse model of amyotrophic lateral sclerosis
    1
    1. scibot 05 May 2021
      RRID:SCR_014210

      DOI: 10.1038/s41598-021-88415-0

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    nature.com/articles/s41598-021-88415-0
  7. Apr 2021
  8. www.sciencedirect.com www.sciencedirect.com
    Periplasmic expression of SpyTagged antibody fragments enables rapid modular antibody assembly
    1
    1. scibot 28 Apr 2021
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      DOI: 10.1016/j.chembiol.2021.01.011

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    sciencedirect.com/science/article/pii/S2451945621000118
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance
    1
    1. scibot 13 Apr 2021
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      DOI: 10.3390/cancers13071648

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    ncbi.nlm.nih.gov/pmc/articles/PMC8037490/
  10. Mar 2021
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enriched environment ameliorates chronic temporal lobe epilepsy‐induced behavioral hyperexcitability and restores synaptic plasticity in CA3–CA1 synapses in male Wistar rats
    1
    1. scibot 19 Mar 2021
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      DOI: 10.1002/jnr.24823

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24823
  12. link.springer.com link.springer.com
    Protecting P-glycoprotein at the blood–brain barrier from degradation in an Alzheimer’s disease mouse model
    1
    1. scibot 11 Mar 2021
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      DOI: 10.1186/s12987-021-00245-4

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    link.springer.com/article/10.1186/s12987-021-00245-4
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ
    1
    1. scibot 09 Mar 2021
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      DOI: 10.1038/s41598-021-83938-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC7925682/
  14. www.sciencedirect.com www.sciencedirect.com
    RADX controls RAD51 filament dynamics to regulate replication fork stability
    1
    1. scibot 01 Mar 2021
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      DOI: 10.1016/j.molcel.2020.12.036

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    sciencedirect.com/science/article/pii/S1097276520309576
  15. Feb 2021
  16. www.sciencedirect.com www.sciencedirect.com
    Unique signatures of stress-induced senescent human astrocytes
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.expneurol.2020.113466

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    sciencedirect.com/science/article/pii/S0014488620302971
  17. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
    1
    1. scibot 24 Feb 2021
      RRID:SCR_01

      DOI: 10.1113/JP280294

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280294
  18. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 24 Feb 2021
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      DOI: 10.1111/bph.15211

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15211
  19. elifesciences.org elifesciences.org
    Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy
    1
    1. scibot 11 Feb 2021
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      DOI: 10.7554/eLife.64434

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    elifesciences.org/articles/64434
  20. www.sciencedirect.com www.sciencedirect.com
    Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs
    1
    1. scibot 04 Feb 2021
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      DOI: 10.1016/j.celrep.2021.108715

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    sciencedirect.com/science/article/pii/S2211124721000280
  21. Jan 2021
  22. www.frontiersin.org www.frontiersin.org
    Melatonin Lowers HIF-1α Content in Human Proximal Tubular Cells (HK-2) Due to Preventing Its Deacetylation by Sirtuin 1
    1
    1. scibot 29 Jan 2021
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      DOI: 10.3389/fphys.2020.572911

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    frontiersin.org/article/10.3389/fphys.2020.572911/full
  23. www.sciencedirect.com www.sciencedirect.com
    Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease
    1
    1. scibot 29 Jan 2021
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      DOI: 10.1016/j.nbd.2021.105278

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    sciencedirect.com/science/article/pii/S0969996121000279
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
    1
    1. scibot 26 Jan 2021
      RRID:SCR_014210

      DOI: 10.1016/j.cell.2020.12.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC7868890/
  25. link.springer.com link.springer.com
    The Choroid Plexus Is an Alternative Source of Prolactin to the Rat Brain
    1
    1. scibot 12 Jan 2021
      RRID:SCR_014210

      DOI: 10.1007/s12035-020-02267-9

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    link.springer.com/article/10.1007/s12035-020-02267-9
  26. Dec 2020
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes
    1
    1. scibot 30 Dec 2020
      RRID:SCR_014210

      DOI: 10.1002/jnr.24775

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24775
  28. www.sciencedirect.com www.sciencedirect.com
    Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions
    1
    1. scibot 23 Dec 2020
      RRID:SCR_014210

      DOI: 10.1016/j.celrep.2020.108538

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    sciencedirect.com/science/article/pii/S2211124720315278
  29. www.frontiersin.org www.frontiersin.org
    Lysine in Combination With Estradiol Promote Dissemination of Estrogen Receptor Positive Breast Cancer via Upregulation of U2AF1 and RPN2 Proteins
    1
    1. scibot 13 Dec 2020
      SCR_014210

      DOI: 10.3389/fonc.2020.598684

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    frontiersin.org/article/10.3389/fonc.2020.598684/full
  30. elifesciences.org elifesciences.org
    RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells
    1
    1. scibot 09 Dec 2020
      RRID:SCR_014210

      DOI: 10.7554/eLife.63452

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    elifesciences.org/articles/63452
  31. www.sciencedirect.com www.sciencedirect.com
    Multiple Alternative Promoters and Alternative Splicing Enable Universal Transcription-Based Logic Computation in Mammalian Cells
    1
    1. scibot 07 Dec 2020
      RRID:SCR_014210

      DOI: 10.1016/j.celrep.2020.108437

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    sciencedirect.com/science/article/pii/S2211124720314261
  32. Nov 2020
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polo-like kinase acts as a molecular timer that safeguards the asymmetric fate of spindle microtubule-organizing centers
    1
    1. scibot 21 Nov 2020
      RRID:SCR_014210

      DOI: 10.7554/eLife.61488

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    ncbi.nlm.nih.gov/pmc/articles/PMC7669271/
  34. Oct 2020
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome
    1
    1. scibot 17 Oct 2020
      RRID:SCR_014210

      DOI: 10.1016/j.celrep.2020.108205

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    ncbi.nlm.nih.gov/pmc/articles/PMC7523552/
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The cell and stress‐specific canonical and noncanonical tRNA cleavage
    1
    1. scibot 16 Oct 2020
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      DOI: 10.1002/jcp.30107

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    onlinelibrary.wiley.com/doi/10.1002/jcp.30107
  37. link.springer.com link.springer.com
    Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β
    1
    1. scibot 13 Oct 2020
      RRID:SCR_014210

      DOI: 10.1007/s43440-020-00162-7

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    link.springer.com/article/10.1007/s43440-020-00162-7
  38. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
    1
    1. scibot 10 Oct 2020
      RRID:SCR_014210

      DOI: 10.1016/j.cell.2020.09.020

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    pubmed.ncbi.nlm.nih.gov/33031745/
  39. www.sciencedirect.com www.sciencedirect.com
    EB1 Directly Regulates APC-Mediated Actin Nucleation
    1
    1. scibot 02 Oct 2020
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      DOI: 10.1016/j.cub.2020.08.094

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    sciencedirect.com/science/article/pii/S0960982220312847
  40. Sep 2020
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome
    1
    1. scibot 30 Sep 2020
      RRID:SCR_014210

      DOI: 10.1016/j.celrep.2020.108205

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    ncbi.nlm.nih.gov/pmc/articles/PMC7523552/
  42. www.sciencedirect.com www.sciencedirect.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    1. scibot 26 Sep 2020
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      DOI: 10.1016/j.cell.2020.02.019

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    sciencedirect.com/science/article/pii/S009286742030163X
  43. www.nature.com www.nature.com
    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
    1
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      DOI: 10.1038/s41419-020-02805-2

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    nature.com/articles/s41419-020-02805-2
  44. www.sciencedirect.com www.sciencedirect.com
    Selective 40S Footprinting Reveals Cap-Tethered Ribosome Scanning in Human Cells
    1
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      DOI: 10.1016/j.molcel.2020.06.005

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    sciencedirect.com/science/article/pii/S1097276520303907
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2
    1
    1. scibot 23 Sep 2020
      RRID:SCR_014210

      DOI: 10.7554/eLife.52276

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    ncbi.nlm.nih.gov/pmc/articles/PMC7141810/
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 23 Sep 2020
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      DOI: 10.1111/bph.15088

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15088
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
    1. scibot 17 Sep 2020
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      DOI: 10.7554/eLife.56913

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen receptor antagonism accelerates disease onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis
    1
    1. scibot 17 Sep 2020
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      DOI: 10.1111/bph.14657

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    ncbi.nlm.nih.gov/pmc/articles/PMC6555856/
  49. www.nature.com www.nature.com
    CRISPR–Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes
    1
    1. scibot 17 Sep 2020
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      DOI: 10.1038/s41596-020-0339-z

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    nature.com/articles/s41596-020-0339-z
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels
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    Dorsal Hippocampal Actin Polymerization is Necessary for Activation of G-protein-Coupled Estrogen Receptor (GPER) to Increase CA1 Dendritic Spine Density and Enhance Memory Consolidation
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    Quantitative immunoblotting analyses reveal that the abundance of actin, tubulin, synaptophysin and EEA1 proteins is altered in the brains of aged mice
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    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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    The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
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    Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila
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    m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination
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    Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures
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    Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin
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    Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning
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    Axonal Degeneration Is Mediated by Necroptosis Activation
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  90. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  91. Nov 2018
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    Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
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    Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
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    A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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    Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells
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    Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease
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    The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection
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    Adipocytes Promote Early Steps of Breast Cancer Cell Dissemination via Interleukin-8
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    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
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    Microglia Responses to Pro-inflammatory Stimuli (LPS, IFNγ+TNFα) and Reprogramming by Resolving Cytokines (IL-4, IL-10)
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    Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer’s Disease Mouse Model
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  105. europepmc.org europepmc.org
    Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?
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  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis
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    ZFAND1 Recruits p97 and the 26S Proteasome to Promote the Clearance of Arsenite-Induced Stress Granules
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    Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels
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    The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity
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    The Monocot-Specific Receptor-like Kinase SDS2 Controls Cell Death and Immunity in Rice
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  112. academic.oup.com academic.oup.com
    Generation of Mouse for Conditional Expression of Forkhead Box A2
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  113. journals.plos.org journals.plos.org
    Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry
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    Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence
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  116. europepmc.org europepmc.org
    A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis.
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  117. Nov 2017
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors
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  122. elifesciences.org elifesciences.org
    Poly(A) tail length regulates PABPC1 expression to tune translation in the heart
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    Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle
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    mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
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    Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
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    Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
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    A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia
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    Circulating Immune Cells Mediate a Systemic RNAi-Based Adaptive Antiviral Response in Drosophila
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    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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    Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
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    An unexpected role for the yeast nucleotide exchange factor Sil1 as a reductant acting on the molecular chaperone BiP
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    elifesciences.org/content/6/e24141
  133. www.jneurosci.org www.jneurosci.org
    Conditional Deletion of the L-Type Calcium Channel Cav1.2 in Oligodendrocyte Progenitor Cells Affects Postnatal Myelination in Mice
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    1. scibot 08 Nov 2017
      SCR_014210

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      RRID:SCR_014210
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    jneurosci.org/content/36/42/10853
  134. www.sciencedirect.com www.sciencedirect.com
    Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
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    1. scibot 08 Nov 2017
      Image Lab software

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S0002929716303391
  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ouabain‐induced changes in MAP kinase phosphorylation in primary culture of rat cerebellar cells
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    1. scibot 08 Nov 2017
      Image Lab

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    onlinelibrary.wiley.com/doi/10.1002/cbf.3199/full
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ear2 Deletion Causes Early Memory and Learning Deficits in APP/PS1 Mice
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    1. scibot 08 Nov 2017
      Chemidoc XRS documentation system

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    ncbi.nlm.nih.gov/pmc/articles/PMC4147626/
  137. www.sciencedirect.com www.sciencedirect.com
    Tumor necrosis factor-inducible gene 6 protein: A novel neuroprotective factor against inflammation-induced developmental brain injury
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    1. scibot 08 Nov 2017
      ImageLab software

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S0014488616300486
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic disruption of the core circadian clock impairs hippocampus-dependent memory
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    1. scibot 08 Nov 2017
      Image Lab

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    ncbi.nlm.nih.gov/pmc/articles/PMC4105720/