787 Matching Annotations
  1. Dec 2021
  2. www.sciencedirect.com www.sciencedirect.com
    DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons
    1
    1. scibot 18 Dec 2021
      RRID:SCR_015687

      DOI: 10.1016/j.isci.2021.103470

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    sciencedirect.com/science/article/pii/S2589004221014413
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
    1
    1. scibot 15 Dec 2021
      RRID:SCR_015687

      DOI: 10.7554/eLife.70992

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    ncbi.nlm.nih.gov/pmc/articles/PMC8664294/
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    Purification of astrocyte subtype based on a double reporter mice approach for downstream transcription profiling
    1
    1. scibot 11 Dec 2021
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      DOI: 10.1016/j.xpro.2021.101009

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    sciencedirect.com/science/article/pii/S2666166721007152
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
    1
    1. scibot 11 Dec 2021
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      DOI: 10.7554/eLife.69056

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639143/
  6. www.sciencedirect.com www.sciencedirect.com
    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.immuni.2021.11.006

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    sciencedirect.com/science/article/pii/S1074761321004970
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    Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1016/j.stem.2021.11.003

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    sciencedirect.com/science/article/pii/S1934590921004513
  8. academic.oup.com academic.oup.com
    Temporal and Spatial Transcriptomic Dynamics across Brain Development in Xenopus laevis tadpoles
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1093/g3journal/jkab387

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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkab387/6423992
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An avian embryo patient-derived xenograft model for preclinical studies of human breast cancers
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.isci.2021.103423

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608609/
  10. Nov 2021
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells
    1
    1. scibot 24 Nov 2021
      RRID:SCR_015687

      DOI: 10.1016/j.isci.2021.103348

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    ncbi.nlm.nih.gov/pmc/articles/PMC8593563/
  12. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
    1
    1. scibot 24 Nov 2021
      RRID:SCR_015687

      DOI: 10.1158/1078-0432.CCR-21-0818

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    clincancerres.aacrjournals.org/content/27/21/5979
  13. 52.53.155.43 52.53.155.43
    ajpcell.00318.2021-html.html
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1152/ajpcell.00318.2021

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    52.53.155.43/b13df6b51a57021899d8a5a0718854bb8095aca3/ajpcell.00318.2021-html.html
  14. www.nature.com www.nature.com
    CHD5 inhibits metastasis of neuroblastoma
    1
    1. scibot 21 Nov 2021
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      DOI: 10.1038/s41388-021-02081-0

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    nature.com/articles/s41388-021-02081-0
  15. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 19 Nov 2021
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      DOI: 10.1111/bph.15667

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15667
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 17 Nov 2021
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      DOI: 10.1002/1878-0261.13115

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13115
  17. www.sciencedirect.com www.sciencedirect.com
    Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
    1
    1. scibot 17 Nov 2021
      RRID:SCR_015687

      DOI: 10.1016/j.celrep.2021.110014

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    sciencedirect.com/science/article/pii/S2211124721014960
  18. www.sciencedirect.com www.sciencedirect.com
    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
    1
    1. scibot 12 Nov 2021
      RRID:SCR_015687

      DOI: 10.1016/j.molcel.2021.10.015

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    sciencedirect.com/science/article/pii/S1097276521009072
  19. www.sciencedirect.com www.sciencedirect.com
    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
    1
    1. scibot 11 Nov 2021
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      DOI: 10.1016/j.stem.2021.10.009

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    sciencedirect.com/science/article/pii/S1934590921004215
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1158/1541-7786.MCR-21-0354

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    ncbi.nlm.nih.gov/pmc/articles/PMC8568690/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequence features of retrotransposons allow for epigenetic variability
    1
    1. scibot 05 Nov 2021
      RRID:SCR_015687

      DOI: 10.7554/eLife.71104

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    ncbi.nlm.nih.gov/pmc/articles/PMC8555987/
  22. Oct 2021
  23. www.embopress.org www.embopress.org
    Reprogramming of glucocorticoid receptor function by hypoxia
    1
    1. scibot 27 Oct 2021
      RRID:SCR_015687

      DOI: 10.15252/embr.202153083

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    embopress.org/doi/epdf/10.15252/embr.202153083
  24. academic.oup.com academic.oup.com
    Chromosome-level genome assemblies of Channa argus and Channa maculata and comparative analysis of their temperature adaptability
    1
    1. scibot 26 Oct 2021
      RRID:SCR_015687

      DOI: 10.1093/gigascience/giab070

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    academic.oup.com/gigascience/article/10/10/giab070/6407244
  25. www.sciencedirect.com www.sciencedirect.com
    Glycogen accumulation and phase separation drives liver tumor initiation
    1
    1. scibot 22 Oct 2021
      RRID:SCR_015687

      DOI: 10.1016/j.cell.2021.10.001

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    sciencedirect.com/science/article/pii/S0092867421011752
  26. www.sciencedirect.com www.sciencedirect.com
    Role of miR-2392 in driving SARS-CoV-2 infection
    1
    1. scibot 22 Oct 2021
      RRID:SCR_01568

      DOI: 10.1016/j.celrep.2021.109839

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    sciencedirect.com/science/article/pii/S2211124721013036
  27. www.sciencedirect.com www.sciencedirect.com
    DREAM represses distinct targets by cooperating with different THAP domain proteins
    1
    1. scibot 21 Oct 2021
      RRID:SCR_015687

      DOI: 10.1016/j.celrep.2021.109835

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    sciencedirect.com/science/article/pii/S2211124721012997
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
    1
    1. scibot 20 Oct 2021
      RRID:SCR_015687

      DOI: 10.1158/0008-5472.CAN-21-1545

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    ncbi.nlm.nih.gov/pmc/articles/PMC8723353/
  29. www.sciencedirect.com www.sciencedirect.com
    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    1. scibot 06 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109776

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    sciencedirect.com/science/article/pii/S2211124721012304
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducible and reversible inhibition of miRNA-mediated gene repression in vivo
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    1. scibot 02 Oct 2021
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      DOI: 10.7554/eLife.70948

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    ncbi.nlm.nih.gov/pmc/articles/PMC8476124/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep evolutionary origin of gamete-directed zygote activation by KNOX/BELL transcription factors in green plants
    1
    1. scibot 02 Oct 2021
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      DOI: 10.7554/eLife.57090

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478417/
  32. www.sciencedirect.com www.sciencedirect.com
    A cell-type-specific atlas of the inner ear transcriptional response to acoustic trauma
    1
    1. scibot 01 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109758

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    sciencedirect.com/science/article/pii/S2211124721012122
  33. Sep 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
    1
    1. scibot 30 Sep 2021
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      DOI: 10.1016/j.cmet.2021.09.003

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    sciencedirect.com/science/article/pii/S1550413121004228
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
    1
    1. scibot 28 Sep 2021
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      DOI: 10.7554/eLife.65484

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    ncbi.nlm.nih.gov/pmc/articles/PMC8457837/
  36. elifesciences.org elifesciences.org
    A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons
    1
    1. scibot 28 Sep 2021
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      DOI: 10.7554/eLife.69795

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    elifesciences.org/articles/69795
  37. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  38. link.springer.com link.springer.com
    Elevated transcription of transposable elements is accompanied by het-siRNA-driven de novo DNA methylation in grapevine embryogenic callus
    1
    1. scibot 22 Sep 2021
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      DOI: 10.1186/s12864-021-07973-9

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    link.springer.com/article/10.1186/s12864-021-07973-9
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
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    1. scibot 22 Sep 2021
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      DOI: 10.7554/eLife.65884

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    ncbi.nlm.nih.gov/pmc/articles/PMC8443249/
  40. www.sciencedirect.com www.sciencedirect.com
    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
    1
    1. scibot 17 Sep 2021
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      DOI: 10.1016/j.molcel.2021.08.029

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    sciencedirect.com/science/article/pii/S1097276521006961
  41. www.sciencedirect.com www.sciencedirect.com
    The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
    1
    1. scibot 16 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109694

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    sciencedirect.com/science/article/pii/S2211124721011414
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA
    1
    1. scibot 14 Sep 2021
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      DOI: 10.7554/eLife.67250

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    ncbi.nlm.nih.gov/pmc/articles/PMC8425947/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model
    1
    1. scibot 09 Sep 2021
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      DOI: 10.3389/fcell.2021.710112

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    ncbi.nlm.nih.gov/pmc/articles/PMC8417118/
  44. www.sciencedirect.com www.sciencedirect.com
    Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection
    1
    1. scibot 08 Sep 2021
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      DOI: 10.1016/j.chom.2021.08.010

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    sciencedirect.com/science/article/pii/S1931312821003863
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    Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia
    1
    1. scibot 08 Sep 2021
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      DOI: 10.1016/j.immuni.2021.08.007

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    sciencedirect.com/science/article/pii/S107476132100337X
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition
    1
    1. scibot 04 Sep 2021
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      DOI: 10.3390/ijms22168792

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    Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype
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    Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle
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    NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
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    27-Hydroxycholesterol Promotes Adiposity and Mimics Adipogenic Diet-induced Inflammatory Signaling
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    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
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    Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase
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    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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    Adult sox10+ Cardiomyocytes Contribute to Myocardial Regeneration in the Zebrafish
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    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
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    The Inducible Response of the Nematode Caenorhabditis elegans to Members of Its Natural Microbiota Across Development and Adult Life
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    Transcriptional profiling aligned with in situ expression image analysis reveals mosaically‐expressed molecular markers for GABA neuron sub‐groups in the ventral tegmental area
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    Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
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    To assemble or not to resemble—A validated Comparative Metatranscriptomics Workflow (CoMW)
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    Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia
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    Shear stress and oxygen availability drive differential changes in opossum kidney proximal tubule cell metabolism and endocytosis
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    Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage
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    Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome
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    Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition
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    The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
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    Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance
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    Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia
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    The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
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    IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation
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    Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency
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    Acetylation of Cytidine in mRNA Promotes Translation Efficiency
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    A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire
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    Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
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    Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
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    N6-methyladenine DNA Modification in Glioblastoma
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    Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome
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    Transcriptome profiling of the Olig2-expressing astrocyte subtype reveals their unique molecular signature
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    Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility
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    Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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    Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology
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    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
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    Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila
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    Efficient RNA polymerase II pause release requires U2 snRNP function
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  180. www.sciencedirect.com www.sciencedirect.com
    Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants
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  181. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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  182. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of innate odor preference depends on spontaneous and experiential activities during critical period
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evidence for additive and synergistic action of mammalian enhancers during cell fate determination
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium
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  186. Mar 2021
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria
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  188. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Genomic exploration of the targets of FOXL2 and ESR2 unveils their implication in cell migration, invasion, and adhesion
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Seroconversion stages COVID19 into distinct pathophysiological states
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basis of specificity for a conserved and promiscuous chromatin remodeling protein
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  191. elifesciences.org elifesciences.org
    HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
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    A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
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    Construction of a MicroRNA-Based Nomogram for Prediction of Lung Metastasis in Breast Cancer Patients
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    Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
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  198. Feb 2021
  199. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  200. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Human adipose‐derived stromal/stem cells are distinct from dermal fibroblasts as evaluated by biological characterization and RNA sequencing
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      DOI: 10.1002/cbf.3610

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  201. www.sciencedirect.com www.sciencedirect.com
    Detecting Tumor Antigen-Specific T Cells via Interaction-Dependent Fucosyl-Biotinylation
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      DOI: 10.1016/j.cell.2020.09.048

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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serotonin signaling by maternal neurons upon stress ensures progeny survival
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    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
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    Unique signatures of stress-induced senescent human astrocytes
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      DOI: 10.1016/j.expneurol.2020.113466

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    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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      DOI: 10.1016/j.celrep.2021.108753

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  206. elifesciences.org elifesciences.org
    Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila
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    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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    The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers
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  209. Jan 2021
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
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      DOI: 10.7554/eLife.63545

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  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals
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      DOI: 10.7554/eLife.63088

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  212. academic.oup.com academic.oup.com
    Ecd promotes U5 snRNP maturation and Prp8 stability
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      DOI: 10.1093/nar/gkaa1274

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