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- Nov 2022
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The relative importance of the eosinophilia re-mains to be determined, but several eosinophil products maycause inflammatory damage to the airway (eosinophil peroxi-dase, major basic protein, eosinophil cationic protein, metallo-proteinases, platelet activating factor, and cysteinyl leukotrienes)(75) and, together with histamine, can cause bronchospasm
Eosinophilia puede causar broncoespasmo en conjunto con otros factores
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Patients with mild to moderate COPD exacerbations show anincreased number of eosinophils in their bronchial mucosa (72).Although this suggests an “asthmatic profile,” the observed eo-sinophils are not degranulated (as they would be in asthma) andare not associated with increased IL-5 expression (72).
Por qué los eosinófilos aumentan y cómo son diferentes a el perfil de los pacientes con asma
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