214 Matching Annotations
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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
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    CDK4/6 inhibition sensitizes intracranial tumors to PD-1 blockade in preclinical models of brain metastasis
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      DOI: 10.1158/1078-0432.CCR-23-0433

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    PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
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      DOI: 10.1016/j.xcrm.2024.101649

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  5. www.cell.com www.cell.com
    Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity
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    cell.com/cell-reports-medicine/abstract/S2666-3791(24)00353-7
  6. Jul 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomineralization-inspired synthesis of autologous cancer vaccines for personalized metallo-immunotherapy
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  8. Jun 2024
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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
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    sciencedirect.com/science/article/pii/S2211124724006284
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    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
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      DOI: 10.1016/j.celrep.2024.114289

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  11. May 2024
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance
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  14. www.cell.com www.cell.com
    ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
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    cell.com/iscience/abstract/S2589-0042(24)01022-8
  15. Apr 2024
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    LKB1 prevents ILC2 exhaustion to enhance antitumor immunity
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    1. scibot 26 Apr 2024
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer immunotherapy via synergistic co-activation of myeloid receptors CD40 and Dectin-1
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    1. scibot 24 Apr 2024
      RRID:AB_10949053

      DOI: 10.1126/sciimmunol.adj5097

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    QDPR deficiency drives immune suppression in pancreatic cancer
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    CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer
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    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    sciencedirect.com/science/article/pii/S0092867424003039
  22. Mar 2024
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    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
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    sciencedirect.com/science/article/pii/S2211124724003310
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    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
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    A specific enterotype derived from gut microbiome of older individuals enables favorable responses to immune checkpoint blockade therapy
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    sciencedirect.com/science/article/pii/S1931312824000751
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
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  28. Feb 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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      RRID:AB_10949053

      DOI: 10.1158/2767-9764.CRC-23-0399

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  30. www.mdpi.com www.mdpi.com
    The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model
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      DOI: 10.3390/ijms25031880

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    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
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    sciencedirect.com/science/article/pii/S1550413124000123
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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      RRID:AB_3075399

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  33. Jan 2024
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    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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      DOI: 10.1016/j.ccell.2023.12.018

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    DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities
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      DOI: 10.1016/j.ebiom.2023.104801

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    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
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    A novel translational PET imaging approach to quantifying abscopal immune activation following targeted radiotherapy and checkpoint blockade.
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      DOI: 10.1016/j.ijrobp.2023.12.047

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    sciencedirect.com/science/article/pii/S0360301624000038
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    Interferon-stimulated neutrophils as a predictor of immunotherapy response
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      DOI: 10.1016/j.ccell.2023.12.005

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    sciencedirect.com/science/article/pii/S1535610823004336
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    A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
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      DOI: 10.1016/j.cell.2023.11.037

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  40. Dec 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventive Treatment with PD-1 Antibody Increases Tissue-Resident Memory T Cells Infiltration and Delays Esophageal Carcinogenesis
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      DOI: 10.1158/1940-6207.CAPR-23-0196

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690045/
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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      DOI: 10.1016/j.immuni.2023.11.002

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    sciencedirect.com/science/article/pii/S1074761323004831
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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      DOI: 10.1016/j.xcrm.2023.101303

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    sciencedirect.com/science/article/pii/S2666379123004974
  44. www.science.org www.science.org
    Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1
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      RRID:AB_10949053

      DOI: 10.1126/sciimmunol.adj5097

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  45. 52.53.155.43 52.53.155.43
    capr-23-0196-html.html
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      DOI: 10.1158/1940-6207.capr-23-0196

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  46. Nov 2023
  47. link.springer.com link.springer.com
    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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      RRID:AB_10949053

      DOI: 10.1038/s41586-023-06749-3

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    link.springer.com/article/10.1038/s41586-023-06749-3
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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      DOI: 10.1016/j.celrep.2023.113477

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    An engineered immunocytokine with collagen affinity improves the tumor bioavailability, tolerability, and therapeutic efficacy of IL-2
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    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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  51. Oct 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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    Intermittent fasting induced ketogenesis inhibits mouse epithelial ovarian cancer by promoting antitumor T cell response
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    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation
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  59. dx.doi.org dx.doi.org
    Glioblastoma vascular plasticity limits effector T-cell infiltration and is blocked by cAMP activation
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    Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer
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  61. Sep 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells
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  63. www.sciencedirect.com www.sciencedirect.com
    Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
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  64. Aug 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
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  66. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity
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  67. 52.53.155.43 52.53.155.43
    PIIS2211124723009622-html.html
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  68. www.sciencedirect.com www.sciencedirect.com
    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
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  70. 52.53.155.43 52.53.155.43
    Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells
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  71. 52.53.155.43 52.53.155.43
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OncoLoop: A network-based precision cancer medicine framework
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  73. Jul 2023
  74. www.sciencedirect.com www.sciencedirect.com
    SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
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    A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence
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    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
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  77. Jun 2023
  78. www.sciencedirect.com www.sciencedirect.com
    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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    IFNγ-induced stem-like state of cancer cells as a driver of metastatic progression following immunotherapy
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    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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  84. May 2023
  85. www.sciencedirect.com www.sciencedirect.com
    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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  86. www.nature.com www.nature.com
    Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
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  87. www.sciencedirect.com www.sciencedirect.com
    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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    Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
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  90. www.sciencedirect.com www.sciencedirect.com
    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
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  91. Apr 2023
  92. aacrjournals.org aacrjournals.org
    Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors
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      DOI: 10.1158/1541-7786.MCR-22-0684

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  93. insight.jci.org insight.jci.org
    Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma
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      DOI: 10.1172/jci.insight.157347

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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
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      DOI: 10.1158/0008-5472.CAN-21-4025

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  95. www.sciencedirect.com www.sciencedirect.com
    Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response
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      DOI: 10.1016/j.celrep.2023.112186

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  96. www.sciencedirect.com www.sciencedirect.com
    Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade
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  97. www.sciencedirect.com www.sciencedirect.com
    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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  99. www.sciencedirect.com www.sciencedirect.com
    Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects
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  100. www.sciencedirect.com www.sciencedirect.com
    Lacticaseibacillus rhamnosus Probio-M9 enhanced the antitumor response to anti-PD-1 therapy by modulating intestinal metabolites
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    T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
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  102. Mar 2023
  103. www.sciencedirect.com www.sciencedirect.com
    IFNγ is a central node of cancer immune equilibrium
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  104. www.sciencedirect.com www.sciencedirect.com
    Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy
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  105. Feb 2023
  106. www.sciencedirect.com www.sciencedirect.com
    Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
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  107. www.embopress.org www.embopress.org
    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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  108. Jan 2023
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of mouse model tumor implantation site on acquired resistance to anti-PD-1 immune checkpoint therapy
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  110. www.sciencedirect.com www.sciencedirect.com
    S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas
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    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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  113. Dec 2022
  114. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  115. www.sciencedirect.com www.sciencedirect.com
    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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      DOI: 10.1016/j.ccell.2022.11.014

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  116. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CIt protocol: a blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells.
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
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      DOI: 10.1136/jitc-2022-004806

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  119. Nov 2022
  120. aacrjournals.org aacrjournals.org
    A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression
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      DOI: 10.1158/0008-5472.CAN-21-4045

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    aacrjournals.org/cancerres/article/82/19/3561/709408/A-Novel-Selective-Inhibitor-JBI-589-Targets-PAD4
  121. aacrjournals.org aacrjournals.org
    Phototherapy with cancer-specific nanoporphyrin potentiates immunotherapy in bladder cancer
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      DOI: 10.1158/1078-0432.CCR-22-1362

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  122. www.sciencedirect.com www.sciencedirect.com
    Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
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  123. www.sciencedirect.com www.sciencedirect.com
    Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
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  124. jitc.bmj.com jitc.bmj.com
    Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation
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  125. Oct 2022
  126. 52.53.155.43 52.53.155.43
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  127. www.sciencedirect.com www.sciencedirect.com
    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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  128. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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  129. www.sciencedirect.com www.sciencedirect.com
    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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      DOI: 10.1016/j.cell.2022.09.020

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  130. Sep 2022
  131. www.sciencedirect.com www.sciencedirect.com
    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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  132. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1
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  133. www.sciencedirect.com www.sciencedirect.com
    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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      DOI: 10.1158/2159-8290.CD-21-0694

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  136. Aug 2022
  137. www.sciencedirect.com www.sciencedirect.com
    Tumor targeted 4-1BB agonist antibody-albumin fusions with high-affinity to FcRn induce anti-tumor immunity without toxicity
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  138. www.sciencedirect.com www.sciencedirect.com
    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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  139. www.sciencedirect.com www.sciencedirect.com
    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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  140. www.sciencedirect.com www.sciencedirect.com
    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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  141. Jul 2022
  142. www.sciencedirect.com www.sciencedirect.com
    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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  143. Jun 2022
  144. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
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      DOI: 10.1158/2159-8290.CD-21-1022

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  145. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
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    Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
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    PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
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    Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer
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  149. May 2022
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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    Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
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  152. Apr 2022
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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  154. Mar 2022
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    PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneity of tyrosine-based melanin anabolism regulates pulmonary and cerebral organotropic colonization microenvironment of melanoma cells
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  159. www.sciencedirect.com www.sciencedirect.com
    Promoting antigen escape from dendritic cell endosomes potentiates anti-tumoral immunity
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  160. Feb 2022
  161. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
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  162. Jan 2022
  163. www.sciencedirect.com www.sciencedirect.com
    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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  164. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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  165. Dec 2021
  166. www.nature.com www.nature.com
    Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
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      DOI: 10.1038/s41467-021-27349-7

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  167. www.sciencedirect.com www.sciencedirect.com
    The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor
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      DOI: 10.1016/j.isci.2021.103392

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  169. Nov 2021
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    Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
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      DOI: 10.1016/j.ccell.2021.10.008

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  171. www.sciencedirect.com www.sciencedirect.com
    LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
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  172. Oct 2021
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
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      DOI: 10.1016/j.cell.2021.09.019

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  174. Sep 2021
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
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      DOI: 10.1136/jitc-2021-003100

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    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
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    Effects of exercise and anti-PD-1 on the tumour microenvironment
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      RRID:AB_10

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  178. Aug 2021
  179. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    sciencedirect.com/science/article/pii/S2211124721009463
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  182. www.sciencedirect.com www.sciencedirect.com
    NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines
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      DOI: 10.1016/j.cell.2018.10.028

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    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
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  185. Jul 2021
  186. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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      RRID:AB_10949053

      DOI: 10.1016/j.cell.2018.10.038

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  187. www.ebiomedicine.com www.ebiomedicine.com
    Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma
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    ebiomedicine.com/article/S2352-3964(19)30702-9/abstract
  188. www.sciencedirect.com www.sciencedirect.com
    PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide-mediated chronic inflammation promotes tobacco carcinogen-induced lung cancer and determines the efficacy of immunotherapy
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      DOI: 10.1158/0008-5472.CAN-20-1994

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  191. Jun 2021
  192. www.sciencedirect.com www.sciencedirect.com
    Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
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    Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
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    Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
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    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
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    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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  197. May 2021
  198. cancerres.aacrjournals.org cancerres.aacrjournals.org
    A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma
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  199. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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  205. Apr 2021
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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    CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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  210. Mar 2021
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    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
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      DOI: 10.1126/scisignal.aau4518

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    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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  213. Feb 2021
  214. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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      DOI: 10.1172/jci.insight.134386

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  215. Jan 2021
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    Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma
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  217. Sep 2020
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    FOXD3 Regulates VISTA Expression in Melanoma
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    CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
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  222. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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      DOI: 10.1172/jci.insight.134386

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    Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
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    Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
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  227. Jan 2020
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    Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors
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    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
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    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
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      DOI: 10.1016/j.cell.2019.07.019

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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy
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    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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      DOI: 10.1016/j.celrep.2019.05.020

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    sciencedirect.com/science/article/pii/S221112471930631X
  238. www.cell.com www.cell.com
    Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.04.091

      Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_10949053

      What is this?

      RRID:AB_10949053 RRIDCUR:Validated
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    cell.com/cell-reports/fulltext/S2211-1247(19)30571-6