206 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance
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    1. scibot 21 May 2024
      RRID:AB_10949053

      DOI: 10.1016/j.immuni.2024.04.024

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    sciencedirect.com/science/article/pii/S1074761324002292
  3. May 2024
  4. www.cell.com www.cell.com
    ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
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    1. scibot 10 May 2024
      RRID:AB_10949053

      DOI: 10.1016/j.isci.2024.109800

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    cell.com/iscience/abstract/S2589-0042(24)01022-8
  5. Apr 2024
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    LKB1 prevents ILC2 exhaustion to enhance antitumor immunity
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    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.celrep.2023.113579

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  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer immunotherapy via synergistic co-activation of myeloid receptors CD40 and Dectin-1
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    1. scibot 24 Apr 2024
      RRID:AB_10949053

      DOI: 10.1126/sciimmunol.adj5097

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034815/
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    QDPR deficiency drives immune suppression in pancreatic cancer
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    1. scibot 23 Apr 2024
      RRID:AB_10949053

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    sciencedirect.com/science/article/pii/S1550413124001190
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    CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer
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    sciencedirect.com/science/article/pii/S2666379124001253
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    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S1535610824000916
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  12. Mar 2024
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    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
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    1. scibot 27 Mar 2024
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2024.114003

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    sciencedirect.com/science/article/pii/S2211124724003310
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    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
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    sciencedirect.com/science/article/pii/S1535610824000801
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    A specific enterotype derived from gut microbiome of older individuals enables favorable responses to immune checkpoint blockade therapy
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    1. scibot 21 Mar 2024
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    sciencedirect.com/science/article/pii/S1931312824000751
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    1. scibot 15 Mar 2024
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2024.02.013

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    sciencedirect.com/science/article/pii/S1535610824000576
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    Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
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    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113932

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    sciencedirect.com/science/article/pii/S2211124724002602
  18. Feb 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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    1. scibot 15 Feb 2024
      RRID:AB_10949053

      DOI: 10.1158/2767-9764.CRC-23-0399

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      DOI: 10.1158/2767-9764.CRC-23-0399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
  20. www.mdpi.com www.mdpi.com
    The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model
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    1. scibot 15 Feb 2024
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      DOI: 10.3390/ijms25031880

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    mdpi.com/1422-0067/25/3/1880
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    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
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      DOI: 10.1016/j.cmet.2024.01.012

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    sciencedirect.com/science/article/pii/S1550413124000123
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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    1. scibot 06 Feb 2024
      RRID:AB_3075399

      DOI: 10.1016/j.cmet.2024.01.005

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    sciencedirect.com/science/article/pii/S1550413124000068
  23. Jan 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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    1. scibot 19 Jan 2024
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2023.12.018

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    sciencedirect.com/science/article/pii/S1535610823004464
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    DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities
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    1. scibot 19 Jan 2024
      AB_10949053

      DOI: 10.1016/j.ebiom.2023.104801

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    ncbi.nlm.nih.gov/pmc/articles/PMC10518355/
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    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
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    1. scibot 12 Jan 2024
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2023.12.013

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    sciencedirect.com/science/article/pii/S1535610823004415
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    A novel translational PET imaging approach to quantifying abscopal immune activation following targeted radiotherapy and checkpoint blockade.
    1
    1. scibot 11 Jan 2024
      RRID:AB_10949053

      DOI: 10.1016/j.ijrobp.2023.12.047

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    sciencedirect.com/science/article/pii/S0360301624000038
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    Interferon-stimulated neutrophils as a predictor of immunotherapy response
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    1. scibot 09 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.005

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    sciencedirect.com/science/article/pii/S1535610823004336
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    A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
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    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.11.037

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    sciencedirect.com/science/article/pii/S0092867423013223
  30. Dec 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventive Treatment with PD-1 Antibody Increases Tissue-Resident Memory T Cells Infiltration and Delays Esophageal Carcinogenesis
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      DOI: 10.1158/1940-6207.CAPR-23-0196

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690045/
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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      DOI: 10.1016/j.immuni.2023.11.002

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    sciencedirect.com/science/article/pii/S1074761323004831
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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      DOI: 10.1016/j.xcrm.2023.101303

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    sciencedirect.com/science/article/pii/S2666379123004974
  34. www.science.org www.science.org
    Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1
    1
    1. scibot 01 Dec 2023
      RRID:AB_10949053

      DOI: 10.1126/sciimmunol.adj5097

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    science.org/doi/10.1126/sciimmunol.adj5097
  35. 52.53.155.43 52.53.155.43
    capr-23-0196-html.html
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      DOI: 10.1158/1940-6207.capr-23-0196

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  36. Nov 2023
  37. link.springer.com link.springer.com
    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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      DOI: 10.1038/s41586-023-06749-3

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    link.springer.com/article/10.1038/s41586-023-06749-3
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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      DOI: 10.1016/j.celrep.2023.113477

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    An engineered immunocytokine with collagen affinity improves the tumor bioavailability, tolerability, and therapeutic efficacy of IL-2
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      DOI: 10.1016/j.xcrm.2023.101289

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    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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      DOI: 10.1016/j.isci.2023.108308

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    sciencedirect.com/science/article/pii/S2589004223023854
  41. Oct 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2023.113318

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    sciencedirect.com/science/article/pii/S221112472301330X
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    Intermittent fasting induced ketogenesis inhibits mouse epithelial ovarian cancer by promoting antitumor T cell response
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      DOI: 10.1016/j.isci.2023.107839

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    sciencedirect.com/science/article/pii/S2589004223019168
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    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
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      DOI: 10.1016/j.xcrm.2023.101236

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    sciencedirect.com/science/article/pii/S2666379123004135
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    1. scibot 13 Oct 2023
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2023.09.011

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    sciencedirect.com/science/article/pii/S1535610823003276
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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      DOI: 10.1016/j.ccell.2023.09.001

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    sciencedirect.com/science/article/pii/S1535610823003185
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.007

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    sciencedirect.com/science/article/pii/S1097276523007025
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    Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation
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      DOI: 10.1016/j.celrep.2023.113220

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  49. dx.doi.org dx.doi.org
    Glioblastoma vascular plasticity limits effector T-cell infiltration and is blocked by cAMP activation
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      DOI: 10.1158/2326-6066.CIR-22-0872

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  50. www.sciencedirect.com www.sciencedirect.com
    Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer
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  51. Sep 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells
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  53. www.sciencedirect.com www.sciencedirect.com
    Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
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  54. Aug 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
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  56. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity
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  57. 52.53.155.43 52.53.155.43
    PIIS2211124723009622-html.html
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  58. www.sciencedirect.com www.sciencedirect.com
    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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  59. www.sciencedirect.com www.sciencedirect.com
    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
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  60. 52.53.155.43 52.53.155.43
    Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells
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  61. 52.53.155.43 52.53.155.43
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OncoLoop: A network-based precision cancer medicine framework
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  63. Jul 2023
  64. www.sciencedirect.com www.sciencedirect.com
    SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
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    A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence
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    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
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  67. Jun 2023
  68. www.sciencedirect.com www.sciencedirect.com
    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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  69. www.sciencedirect.com www.sciencedirect.com
    PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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  71. www.sciencedirect.com www.sciencedirect.com
    IFNγ-induced stem-like state of cancer cells as a driver of metastatic progression following immunotherapy
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    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
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  73. www.sciencedirect.com www.sciencedirect.com
    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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  74. May 2023
  75. www.sciencedirect.com www.sciencedirect.com
    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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  76. www.nature.com www.nature.com
    Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
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  77. www.sciencedirect.com www.sciencedirect.com
    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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    Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
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    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
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  81. Apr 2023
  82. aacrjournals.org aacrjournals.org
    Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors
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  83. insight.jci.org insight.jci.org
    Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma
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      DOI: 10.1172/jci.insight.157347

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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
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  85. www.sciencedirect.com www.sciencedirect.com
    Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response
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    Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade
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    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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    Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects
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  90. www.sciencedirect.com www.sciencedirect.com
    Lacticaseibacillus rhamnosus Probio-M9 enhanced the antitumor response to anti-PD-1 therapy by modulating intestinal metabolites
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      DOI: 10.1016/j.ebiom.2023.104533

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  91. www.sciencedirect.com www.sciencedirect.com
    T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
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  92. Mar 2023
  93. www.sciencedirect.com www.sciencedirect.com
    IFNγ is a central node of cancer immune equilibrium
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    Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy
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  95. Feb 2023
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    Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
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  97. www.embopress.org www.embopress.org
    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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      DOI: 10.15252/embr.202256524

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  98. Jan 2023
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of mouse model tumor implantation site on acquired resistance to anti-PD-1 immune checkpoint therapy
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    S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas
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    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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  103. Dec 2022
  104. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CIt protocol: a blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells.
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    Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
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  109. Nov 2022
  110. aacrjournals.org aacrjournals.org
    A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression
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  111. aacrjournals.org aacrjournals.org
    Phototherapy with cancer-specific nanoporphyrin potentiates immunotherapy in bladder cancer
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  112. www.sciencedirect.com www.sciencedirect.com
    Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
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    Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
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  114. jitc.bmj.com jitc.bmj.com
    Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation
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  115. Oct 2022
  116. 52.53.155.43 52.53.155.43
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  117. www.sciencedirect.com www.sciencedirect.com
    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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      DOI: 10.1016/j.cmet.2022.09.021

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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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      DOI: 10.1016/j.cell.2022.09.020

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  120. Sep 2022
  121. www.sciencedirect.com www.sciencedirect.com
    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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    Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1
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    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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      DOI: 10.1158/2159-8290.CD-21-0694

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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  126. Aug 2022
  127. www.sciencedirect.com www.sciencedirect.com
    Tumor targeted 4-1BB agonist antibody-albumin fusions with high-affinity to FcRn induce anti-tumor immunity without toxicity
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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  130. www.sciencedirect.com www.sciencedirect.com
    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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  131. Jul 2022
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    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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  133. Jun 2022
  134. 52.53.155.43 52.53.155.43
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  135. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
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    Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
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    PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
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    Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer
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  139. May 2022
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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    Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
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  142. Apr 2022
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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  144. Mar 2022
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    PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneity of tyrosine-based melanin anabolism regulates pulmonary and cerebral organotropic colonization microenvironment of melanoma cells
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  149. www.sciencedirect.com www.sciencedirect.com
    Promoting antigen escape from dendritic cell endosomes potentiates anti-tumoral immunity
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  150. Feb 2022
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    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
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  152. Jan 2022
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    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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  155. Dec 2021
  156. www.nature.com www.nature.com
    Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
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  157. www.sciencedirect.com www.sciencedirect.com
    The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor
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  159. Nov 2021
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    Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
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    LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
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  162. Oct 2021
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
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  164. Sep 2021
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
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      DOI: 10.1136/jitc-2021-003100

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    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
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    Effects of exercise and anti-PD-1 on the tumour microenvironment
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      RRID:AB_10

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  168. Aug 2021
  169. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    sciencedirect.com/science/article/pii/S2211124718318102
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    NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines
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      DOI: 10.1016/j.cell.2018.10.028

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    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
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  175. Jul 2021
  176. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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      RRID:AB_10949053

      DOI: 10.1016/j.cell.2018.10.038

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    Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma
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    ebiomedicine.com/article/S2352-3964(19)30702-9/abstract
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    PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
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    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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    Lipopolysaccharide-mediated chronic inflammation promotes tobacco carcinogen-induced lung cancer and determines the efficacy of immunotherapy
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  181. Jun 2021
  182. www.sciencedirect.com www.sciencedirect.com
    Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
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    Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
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    Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
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    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
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    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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  187. May 2021
  188. cancerres.aacrjournals.org cancerres.aacrjournals.org
    A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma
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      DOI: 10.1158/0008-5472.CAN-20-3510

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  189. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15457

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15457
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    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
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      DOI: 10.1016/j.stem.2020.06.022

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    sciencedirect.com/science/article/pii/S1934590920302897
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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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  195. Apr 2021
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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    CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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  200. Mar 2021
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    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
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    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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  203. Feb 2021
  204. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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  205. Jan 2021
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    Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma
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  207. Sep 2020
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    FOXD3 Regulates VISTA Expression in Melanoma
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    CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
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    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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    Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
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    Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
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  217. Jan 2020
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    Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors
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    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
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      DOI: 10.1016/j.cell.2019.10.028

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  220. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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      DOI: 10.1016/j.celrep.2019.07.044

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    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
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      DOI: 10.1016/j.cell.2019.07.019

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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy
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      DOI: 10.1016/j.cell.2019.10.029

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    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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      DOI: 10.1016/j.celrep.2019.05.020

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  228. www.cell.com www.cell.com
    Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
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      DOI: 10.1016/j.celrep.2019.04.091

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    cell.com/cell-reports/fulltext/S2211-1247(19)30571-6
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      DOI: 10.1016/j.immuni.2018.12.021

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    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
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  231. Nov 2018
  232. www.sciencedirect.com www.sciencedirect.com
    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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    IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy
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    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
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    Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
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    Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
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    sciencedirect.com/science/article/pii/S1550413118301177
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    Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
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    1. scibot 05 Nov 2018
      RRID:AB_10949053

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      (Bio X Cell Cat# BE0146, RRID:AB_10949053)

      SciCrunch record: RRID:AB_10949053

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_10949053
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    sciencedirect.com/science/article/pii/S1074761317305332