532 Matching Annotations
  1. Oct 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P16INK4A drives RB1 degradation by UTP14A-catalyzed K810 ubiquitination
    1
    1. scibot 05 Oct 2024
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2024.110882

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    ncbi.nlm.nih.gov/pmc/articles/PMC11440251/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion
    1
    1. scibot 04 Oct 2024
      RRID:AB_2107436

      DOI: 10.1158/1541-7786.MCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC11445649/
  4. www.sciencedirect.com www.sciencedirect.com
    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
    1
    1. scibot 02 Oct 2024
      AB_2107436

      DOI: 10.1016/j.celrep.2024.114794

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    sciencedirect.com/science/article/pii/S2211124724011458
  5. www.sciencedirect.com www.sciencedirect.com
    Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
    1
    1. scibot 02 Oct 2024
      AB_2107436

      DOI: 10.1016/j.stem.2024.09.008

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    sciencedirect.com/science/article/pii/S1934590924003229
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
    1
    1. scibot 02 Oct 2024
      RRID:AB_2107436

      DOI: 10.4103/1673-5374.392889

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    ncbi.nlm.nih.gov/pmc/articles/PMC11433893/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
    1
    1. scibot 02 Oct 2024
      RRID:AB_2107436

      DOI: 10.4103/NRR.NRR-D-23-01592

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    ncbi.nlm.nih.gov/pmc/articles/PMC11433901/
  8. Sep 2024
  9. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Brown adipose tissue-derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway
    1
    1. scibot 28 Sep 2024
      RRID:AB_2107436

      DOI: 10.1096/fj.202401346R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401346R
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    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
    1
    1. scibot 27 Sep 2024
      AB_2107436

      DOI: 10.1016/j.celrep.2024.114756

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    sciencedirect.com/science/article/pii/S2211124724011070
  11. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    An adenosinergic positive feedback loop extends pharmacological cardioprotection duration
    1
    1. scibot 27 Sep 2024
      RRID:AB_2107436

      DOI: 10.1111/bph.17331

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17331
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
    1
    1. scibot 25 Sep 2024
      AB_2107436

      DOI: 10.1016/j.molcel.2024.08.026

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    sciencedirect.com/science/article/pii/S1097276524007032
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of mitochondrial autophagy in osteoarthritis
    1
    1. scibot 25 Sep 2024
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2024.110741

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    ncbi.nlm.nih.gov/pmc/articles/PMC11402317/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis
    1
    1. scibot 18 Sep 2024
      RRID:AB_2107436

      DOI: 10.1186/s12951-024-02795-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11391629/
  15. www.sciencedirect.com www.sciencedirect.com
    Downregulation of Chloride voltage-gated channel 7 contributes to hyperalgesia following spared nerve injury
    1
    1. scibot 17 Sep 2024
      RRID:AB_2107436

      DOI: 10.1016/j.jbc.2024.107779

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    sciencedirect.com/science/article/pii/S0021925824022804
  16. www.sciencedirect.com www.sciencedirect.com
    Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB
    1
    1. scibot 13 Sep 2024
      RRID:AB_2107436

      DOI: 10.1016/j.heliyon.2024.e37753

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    sciencedirect.com/science/article/pii/S240584402413784X
  17. Aug 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
    1
    1. scibot 25 Aug 2024
      RRID:AB_2107436

      DOI: 10.1016/j.xcrm.2024.101686

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    ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TMEM252 inhibits epithelial–mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression
    1
    1. scibot 25 Aug 2024
      RRID:AB_2107436

      DOI: 10.1002/hed.27922

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    onlinelibrary.wiley.com/doi/10.1002/hed.27922
  20. www.nature.com www.nature.com
    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
    1
    1. scibot 23 Aug 2024
      RRID:AB_2107436

      DOI: 10.1038/s42255-024-01110-y

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    nature.com/articles/s42255-024-01110-y
  21. www.sciencedirect.com www.sciencedirect.com
    Structural basis for the transport and substrate selection of human urate transporter 1
    1
    1. scibot 22 Aug 2024
      RRID:AB_2107436

      DOI: 10.1016/j.celrep.2024.114628

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    sciencedirect.com/science/article/pii/S2211124724009781
  22. www.sciencedirect.com www.sciencedirect.com
    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
    1
    1. scibot 20 Aug 2024
      AB_2107436

      DOI: 10.1016/j.celrep.2024.114617

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    sciencedirect.com/science/article/pii/S2211124724009677
  23. www.sciencedirect.com www.sciencedirect.com
    Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation
    1
    1. scibot 20 Aug 2024
      RRID:AB_2107436

      DOI: 10.1016/j.scr.2024.103531

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    sciencedirect.com/science/article/pii/S1873506124002290
  24. www.sciencedirect.com www.sciencedirect.com
    Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
    1
    1. scibot 19 Aug 2024
      AB_2107436

      DOI: 10.1016/j.cmet.2024.07.011

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    sciencedirect.com/science/article/pii/S1550413124002821
  25. academic.oup.com academic.oup.com
    Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6
    1
    1. scibot 02 Aug 2024
      60004-1-Ig

      DOI: 10.1093/cercor/bhab242

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    academic.oup.com/cercor/advance-article-abstract/doi/10.1093/cercor/bhab242/6338536
  26. Jul 2024
  27. link.springer.com link.springer.com
    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
    1
    1. scibot 30 Jul 2024
      RRID:AB_2107436

      DOI: 10.1007/s00018-024-05285-1

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    link.springer.com/article/10.1007/s00018-024-05285-1
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
    1
    1. scibot 27 Jul 2024
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2024.110285

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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
  29. 52.53.155.43 52.53.155.43
    Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage
    1
    1. scibot 26 Jul 2024
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2024.110507

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    52.53.155.43/e9c57a9d42b1c2a342f0d34ee7a75c66e8f5b9d0/1-s2.0-S2589004224017322-main-html.html
  30. 52.53.155.43 52.53.155.43
    Cancer-associated endocrine cells participate in pancreatic carcinogenesis
    1
    1. scibot 25 Jul 2024
      RRID:AB_2107436

      DOI: 10.1053/j.gastro.2024.07.016

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    52.53.155.43/00ed7388bef43fd34d4811e77f0e00ce1748f907/1-s2.0-S0016508524052259-main-html.html
  31. www.sciencedirect.com www.sciencedirect.com
    A hominoid-specific signaling axis regulating the tempo of synaptic maturation
    1
    1. scibot 25 Jul 2024
      AB_2107436

      DOI: 10.1016/j.celrep.2024.114548

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    sciencedirect.com/science/article/pii/S2211124724008775
  32. www.sciencedirect.com www.sciencedirect.com
    Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear
    1
    1. scibot 24 Jul 2024
      AB_2107436

      DOI: 10.1016/j.isci.2024.110331

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    sciencedirect.com/science/article/pii/S2589004224015566
  33. www.sciencedirect.com www.sciencedirect.com
    The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
    1
    1. scibot 23 Jul 2024
      AB_2107436

      DOI: 10.1016/j.devcel.2024.06.001

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    sciencedirect.com/science/article/pii/S1534580724003794
  34. www.sciencedirect.com www.sciencedirect.com
    The impact of quercetin and paclitaxel combination on ovarian cancer cells
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.isci.2024.110434

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    sciencedirect.com/science/article/pii/S2589004224016596
  35. nyaspubs.onlinelibrary.wiley.com nyaspubs.onlinelibrary.wiley.com
    NAcM-OPT protects keratinocytes from H2O2-induced cell damage by promoting autophagy
    1
    1. scibot 18 Jul 2024
      RRID:AB_2107436

      DOI: 10.1111/nyas.15173

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    nyaspubs.onlinelibrary.wiley.com/doi/10.1111/nyas.15173
  36. www.sciencedirect.com www.sciencedirect.com
    Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.isci.2024.110293

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    sciencedirect.com/science/article/pii/S2589004224015189
  37. www.sciencedirect.com www.sciencedirect.com
    PIK3CA mutations enhance the adipogenesis of ADSCs in facial infiltrating lipomatosis through TRPV1
    1
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      DOI: 10.1016/j.isci.2024.110467

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    sciencedirect.com/science/article/pii/S2589004224016924
  38. www.sciencedirect.com www.sciencedirect.com
    Protocol for evaluating the effects of large gradient high magnetic fields on osteocyte function
    1
    1. scibot 18 Jul 2024
      AB_210743

      DOI: 10.1016/j.xpro.2024.103186

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    sciencedirect.com/science/article/pii/S2666166724003514
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4
    1
    1. scibot 17 Jul 2024
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2024.110163

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    ncbi.nlm.nih.gov/pmc/articles/PMC11226984/
  40. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Jul 2024
      RRID:AB_2107436

      DOI: 10.1111/bph.16484

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16484
  41. www.sciencedirect.com www.sciencedirect.com
    Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3
    1
    1. scibot 12 Jul 2024
      RRID:AB_2107436

      DOI: 10.1016/j.celrep.2024.114478

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    sciencedirect.com/science/article/pii/S2211124724008076
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury
    1
    1. scibot 06 Jul 2024
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      DOI: 10.1038/s41419-024-06826-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11220046/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ROS are required for the germinative cell proliferation and metacestode larval growth of Echinococcus multilocularis
    1
    1. scibot 03 Jul 2024
      RRID:AB_2107436

      DOI: 10.3389/fmicb.2024.1410504

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    Acetyl-NPKY of Integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
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    Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15
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    A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer
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    Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype
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    PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR
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    Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma
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    AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis
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    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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  86. Mar 2024
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    The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD
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    Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle
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    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
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    Glioblastoma stem cell-derived exosomal miR-374b-3p promotes tumor angiogenesis and progression through inducing M2 macrophages polarization
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    DDX3 regulates cancer immune surveillance via 3′ UTR-mediated cell-surface expression of PD-L1
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    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
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    Microglia-Endothelial Cross-Talk Mediating Retinal Vascular Dysfunction through Remodeling Inflammatory Microenvironment in Diabetic Retinopathy
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    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
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    Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
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    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BHLHE41 Suppresses Osteoclastogenesis and Abnormal Bone Resorption Disease via NFATc1
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    Targeting blood brain barrier—Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats
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    FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila
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    Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats
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    Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves
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    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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    TGF-β2 regulates neuronal Ankyrin-G and promotes its interaction with KCC2
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    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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    Comparative analyses of the Smith−Magenis syndrome protein RAI1 in mice and common marmoset monkeys
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    Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients
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    Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB
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    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts
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    Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration
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    Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
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    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival
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    ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures
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    Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity
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    Generation of CRISPR-Cas9 edited human induced pluripotent stem cell line carrying BAG3 V468M mutation in its BAG domain
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects
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    Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation
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    GDF15 is a major determinant of ketogenic diet-induced weight loss
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    NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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    APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread
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    Synonymous codon usage regulates translation initiation
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    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
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    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
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    Multi-omics analyses reveal bacteria and catalase associated with keloid disease
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    The hypothalamic steroidogenic pathway mediates susceptibility to inflammation-evoked depression in female mice
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    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis
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    Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma
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    m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
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    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
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    Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction
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    Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP
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    JUN mediates Glucocorticoid Resistance by stabilizing HIF1a in T-Cell Acute Lymphoblastic Leukemia
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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    Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia
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    Methotrexate-based PROTACs as DHFR-specific chemical probes
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    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
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    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
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    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
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  201. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Han-html.html
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    1. scibot 16 Aug 2023
      RRID:AB_2107436

      DOI: 10.1111/bph.16208

      Resource: (Proteintech Cat# 60004-1-Ig, RRID:AB_2107436)

      Curator: @scibot

      SciCrunch record: RRID:AB_2107436

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      RRID:AB_2107436
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    52.53.155.43/5e554e9cedd6e38ae632f7a8eb735fb3080af333/British J Pharmacology - 2023 - Han-html.html