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    The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure
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    1. scibot 28 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039345/
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    sciencedirect.com/science/article/pii/S0092867424003131
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    5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation
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    onlinelibrary.wiley.com/doi/10.1002/brb3.3487
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    sciencedirect.com/science/article/pii/S1534580724002272
  6. Apr 2024
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    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
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    sciencedirect.com/science/article/pii/S1074761324001420
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    Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1
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    onlinelibrary.wiley.com/doi/10.1002/mc.23722
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    The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
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    sciencedirect.com/science/article/pii/S1535610824000941
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    Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling
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    sciencedirect.com/science/article/pii/S089662732400165X
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    Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
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    sciencedirect.com/science/article/pii/S1550413124000895
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    12958_2024_1204_MOESM1_ESM-html.html
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction
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    sciencedirect.com/science/article/pii/S2211124724003425
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    Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
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    AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis
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    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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  18. Mar 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD
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    Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle
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    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
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    Glioblastoma stem cell-derived exosomal miR-374b-3p promotes tumor angiogenesis and progression through inducing M2 macrophages polarization
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    DDX3 regulates cancer immune surveillance via 3′ UTR-mediated cell-surface expression of PD-L1
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    sciencedirect.com/science/article/pii/S2211124724002651
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    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
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    A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice
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    sciencedirect.com/science/article/pii/S1097276524001382
  26. Feb 2024
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    Microglia-Endothelial Cross-Talk Mediating Retinal Vascular Dysfunction through Remodeling Inflammatory Microenvironment in Diabetic Retinopathy
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    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
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    Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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      DOI: 10.1158/2326-6066.CIR-23-0211

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    aacrjournals.org/cancerimmunolres/article/12/2/232/733764/Single-Cell-Transcriptomics-Reveals-the
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    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
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    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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      DOI: 10.1186/s12974-024-03051-5

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  33. aacrjournals.org aacrjournals.org
    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion
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      DOI: 10.1158/0008-5472.CAN-23-2049

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    aacrjournals.org/cancerres/article/84/3/405/733849/RNA-Methyltransferase-FTSJ3-Regulates-the-Type-I
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BHLHE41 Suppresses Osteoclastogenesis and Abnormal Bone Resorption Disease via NFATc1
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  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting blood brain barrier—Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats
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    FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila
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  37. dx.doi.org dx.doi.org
    Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats
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      DOI: 10.1210/endocr/bqae012

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    Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves
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  39. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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    Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients
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    Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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  80. www.sciencedirect.com www.sciencedirect.com
    VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis
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    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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    Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma
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    m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
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    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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  86. Nov 2023
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
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    Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction
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    Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP
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    Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
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    Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization
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    JUN mediates Glucocorticoid Resistance by stabilizing HIF1a in T-Cell Acute Lymphoblastic Leukemia
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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    Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
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    The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy
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  101. Oct 2023
  102. 52.53.155.43 52.53.155.43
    bqad159-html.html
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    Methotrexate-based PROTACs as DHFR-specific chemical probes
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    MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis
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    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
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    Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria
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    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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  108. www.nature.com www.nature.com
    SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy
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    The splicing factor DHX38 enables retinal development through safeguarding genome integrity
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    Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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  112. www.cell.com www.cell.com
    CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signalling pathway
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    Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD
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    CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation
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  116. Sep 2023
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
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    Signaling protein abundance modulates the strength of the spindle assembly checkpoint
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the wnt/β-catenin signaling pathway
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    Spinal TAOK2 contributes to neuropathic pain via cGAS-STING activation in rats
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    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
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    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
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    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
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  133. 52.53.155.43 52.53.155.43
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity
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    Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
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  138. Jul 2023
  139. www.sciencedirect.com www.sciencedirect.com
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    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
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    Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis
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    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
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    Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity
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  152. Jun 2023
  153. portlandpress.com portlandpress.com
    Akt2 deficiency alleviates oxidative stress in the heart and liver via upregulating SIRT6 during high-fat diet-induced obesity
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    Photobiomodulation inhibits the expression of chondroitin... : Neural Regeneration Research
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response
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    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
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    Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy
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    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
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    Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury
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    Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers
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    The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I–Mediated Immune Response
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    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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    FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
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    16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice
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    Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections
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    YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis
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