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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phospholipase D Family Member 4 Regulates Microglial Phagocytosis and Remyelination via the AKT Pathway in a Cuprizone‐Induced Multiple Sclerosis Mouse Model
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  3. 52.53.155.43 52.53.155.43
    ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway-html.html
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    52.53.155.43/7324a4302b92926502f88e0cd10bf0b0ca3de710/ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway-html.html
  4. Dec 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer
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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy
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    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    Energetics of cholesterol perception and translocation in the human Smoothened receptor
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    Genetic and microenvironmental evolution of colorectal liver metastases under chemotherapy
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    Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4+ T cell for inflammatory bowel diseases treatment
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    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    Structure-guided development of selective caseinolytic protease P agonists as antistaphylococcal agents
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    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
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  15. Nov 2024
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    Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells
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    Genome-wide mapping of native co-localized G4s and R-loops in living cells
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      DOI: 10.7554/eLife.99026

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  21. journals.lww.com journals.lww.com
    Reduced mesencephalic astrocyte-derived neurotrophic factor ... : Neural Regeneration Research
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      DOI: 10.4103/NRR.NRR-D-23-01666

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  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms
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  24. Oct 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P16INK4A drives RB1 degradation by UTP14A-catalyzed K810 ubiquitination
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    NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion
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    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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    Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
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  31. Sep 2024
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    Brown adipose tissue-derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway
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    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
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    An adenosinergic positive feedback loop extends pharmacological cardioprotection duration
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of mitochondrial autophagy in osteoarthritis
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis
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    Downregulation of Chloride voltage-gated channel 7 contributes to hyperalgesia following spared nerve injury
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    Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB
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  40. Aug 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    TMEM252 inhibits epithelial–mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression
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    onlinelibrary.wiley.com/doi/10.1002/hed.27922
  43. www.nature.com www.nature.com
    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
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  44. www.cell.com www.cell.com
    Structural basis for the transport and substrate selection of human urate transporter 1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00978-1
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    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
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    Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6
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    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
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    Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage
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    Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15
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    Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype
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    PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR
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    Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
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    Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma
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    The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration
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    Structural and functional insights into yeast Tbf1 as an atypical telomeric repeat-binding factor
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    The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
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    Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1
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    The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
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    Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling
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    Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
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  104. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction
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    Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
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    AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis
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    The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD
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    Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle
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    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
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    Glioblastoma stem cell-derived exosomal miR-374b-3p promotes tumor angiogenesis and progression through inducing M2 macrophages polarization
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    DDX3 regulates cancer immune surveillance via 3′ UTR-mediated cell-surface expression of PD-L1
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    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
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    Microglia-Endothelial Cross-Talk Mediating Retinal Vascular Dysfunction through Remodeling Inflammatory Microenvironment in Diabetic Retinopathy
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    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
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    Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
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    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion
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    Targeting blood brain barrier—Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats
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    FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila
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    Lifespan Effects of Muscle-Specific Androgen Receptor Overexpression on Body Composition of Male and Female Rats
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    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
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    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
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    Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients
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    Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration
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    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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    Synonymous codon usage regulates translation initiation
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    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
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    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
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    Multi-omics analyses reveal bacteria and catalase associated with keloid disease
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    The hypothalamic steroidogenic pathway mediates susceptibility to inflammation-evoked depression in female mice
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    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis
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    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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    Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma
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    m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
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    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
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    Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction
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    Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP
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    Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
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    JUN mediates Glucocorticoid Resistance by stabilizing HIF1a in T-Cell Acute Lymphoblastic Leukemia
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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    Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia
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    Methotrexate-based PROTACs as DHFR-specific chemical probes
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    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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    The splicing factor DHX38 enables retinal development through safeguarding genome integrity
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    Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    cell.com/iscience/abstract/S2589-0042(23)02147-8
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    Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells
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    1. scibot 13 Oct 2023
      RRID:AB_2107436

      DOI: 10.1016/j.celrep.2023.113213

      Resource: (Proteintech Cat# 60004-1-Ig, RRID:AB_2107436)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124723012251