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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of Bradykinin B2 Receptors in Astrocytes Stimulates the Release of Leukemia Inhibitory Factor for Autocrine and Paracrine Signaling
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    1. scibot 22 Dec 2024
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      DOI: 10.3390/ijms252313079

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    pmc.ncbi.nlm.nih.gov/articles/PMC11642044/
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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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    sciencedirect.com/science/article/pii/S2211124724014554
  4. Dec 2024
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    IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
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    sciencedirect.com/science/article/pii/S2211124724013901
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.cell.2024.11.009

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    sciencedirect.com/science/article/pii/S0092867424013266
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    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    1. scibot 03 Dec 2024
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      DOI: 10.1126/scisignal.adp1375

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    Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0896627324008006
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    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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    sciencedirect.com/science/article/pii/S1097276524008840
  10. Nov 2024
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    HucMSCs can alleviate abnormal vasculogenesis induced by high glucose through the MAPK signaling pathway
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    sciencedirect.com/science/article/pii/S2589004224025793
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    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    1. scibot 14 Nov 2024
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    sciencedirect.com/science/article/pii/S2451945624004434
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    1. scibot 10 Nov 2024
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      DOI: 10.2147/JIR.S481101

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  14. Sep 2024
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    TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus
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    1. scibot 27 Sep 2024
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    FNIP1 suppresses colorectal cancer progression through inhibiting STAT3 phosphorylation and nuclear translocation
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    1. scibot 25 Sep 2024
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      DOI: 10.1111/bph.15169

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      Curator comments: p38 MAPK (D13E1) XP Rabbit mAb antibody Cell Signaling Technology Cat# 8690

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      Curator comments: Phospho-p38 MAPK (Thr180/Tyr182) (D3F9) XP Rabbit mAb antibody Cell Signaling Technology Cat# 4511

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    Key roles of C2/GAP domains in SYNGAP1-related pathophysiology
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    sciencedirect.com/science/article/pii/S2211124724010842
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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    sciencedirect.com/science/article/pii/S2211124724010726
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    sciencedirect.com/science/article/pii/S0092867424009048
  21. Aug 2024
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
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    sciencedirect.com/science/article/pii/S2211124724009914
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    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
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    sciencedirect.com/science/article/pii/S2211124724009586
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    Senescent endometrial stromal cells transmit reactive oxygen species to the trophoblast-like cells and impair spreading of blastocyst-like spheroids
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      DOI: 10.1093/molehr/gaac039

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    academic.oup.com/molehr/article/28/12/gaac039/6825317
  25. Jul 2024
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    sciencedirect.com/science/article/pii/S2666379124003276
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    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    1. scibot 20 Jul 2024
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      DOI: 10.7554/eLife.91766

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
  28. Jun 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Minocycline Abrogates Individual Differences in Nerve Injury-Evoked Affective Disturbances in Male Rats and Prevents Associated Supraspinal Neuroinflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11180027/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice
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      DOI: 10.3389/fphar.2024.1385330

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    SARS-CoV-2 envelope protein regulates innate immune tolerance
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GLUT2 regulation of p38 MAPK isoform protein expression and p38 phosphorylation in male versus female rat hypothalamic primary astrocyte Cultures
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      DOI: 10.1016/j.ibneur.2024.05.008

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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  34. May 2024
  35. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
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      DOI: 10.1113/JP285719

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    sciencedirect.com/science/article/pii/S1074761324002309
  37. 52.53.155.43 52.53.155.43
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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      DOI: 10.20944/preprints202402.1027.v1

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      DOI: 10.20944/preprints202402.1027.v1

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    Host-pathogen Coadaptation by running with PAR protein
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    52.53.155.43/ed26dad54fa8ad8f27865dcc79d9a69d83befd62/2024.01.31.578330v1.full-html.html
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16356
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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    sciencedirect.com/science/article/pii/S1934590924001292
  41. Apr 2024
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    Lysosomal dysfunction by inactivation of V-ATPase drives innate immune response in C. elegans
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    sciencedirect.com/science/article/pii/S2211124724004662
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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      DOI: 10.7554/eLife.94265

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    ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    sciencedirect.com/science/article/pii/S0006295224002132
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    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
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    sciencedirect.com/science/article/pii/S0753332224004591
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    sciencedirect.com/science/article/pii/S2211124724003978
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    SWI/SNF complex-mediated chromatin remodelling in Candida glabrata promotes immune evasion
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  89. Sep 2023
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    Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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  200. Oct 2021
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    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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    KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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  222. Jul 2021
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    Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats
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    Peripheral Nerve Injury Triggers Neuroinflammation in the Medial Prefrontal Cortex and Ventral Hippocampus in a Subgroup of Rats with Coincident Affective Behavioural Changes
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    Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain
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