262 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
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    1. scibot 12 Apr 2024
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    sciencedirect.com/science/article/pii/S0753332224004591
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    sciencedirect.com/science/article/pii/S2211124724003978
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    SWI/SNF complex-mediated chromatin remodelling in Candida glabrata promotes immune evasion
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      DOI: 10.1016/j.isci.2024.109607

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    sciencedirect.com/science/article/pii/S2589004224008290
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    1. scibot 10 Apr 2024
      RRID:AB_2139682

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
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    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    1. scibot 03 Apr 2024
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      DOI: 10.3390/ijms25063343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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    sciencedirect.com/science/article/pii/S209012322400119X
  8. Mar 2024
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    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
    1
    1. scibot 29 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003267
  10. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
    2
    1. scibot 29 Mar 2024
      AB_2139682

      DOI: 10.1210/endocr/bqae035

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      AB_2139682

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    52.53.155.43/ef706d7fedeb9d14a9f80c03d77786b7f4c289d6/bqae035-html.html
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
    1
    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S0092867424002253
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
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    1. scibot 16 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  13. 52.53.155.43 52.53.155.43
    NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38MAPK/MK2 phosphorylation in S. Typhimurium infection
    1
    1. scibot 08 Mar 2024
      AB_2139682

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  14. Feb 2024
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    Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1
    1
    1. scibot 27 Feb 2024
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    sciencedirect.com/science/article/abs/pii/S1550413124000147
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
    2
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      DOI: 10.1016/j.celrep.2024.113795

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    sciencedirect.com/science/article/pii/S2211124724001232
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    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
    1
    1. scibot 15 Feb 2024
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    embopress.org/doi/10.1038/s44319-024-00077-x
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    Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells
    1
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    sciencedirect.com/science/article/pii/S1097276524000510
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.cmet.2023.10.018

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    sciencedirect.com/science/article/pii/S1550413123004126
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838806/
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.004

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    sciencedirect.com/science/article/pii/S0092867424000060
  22. Jan 2024
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
    1
    1. scibot 23 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pdgfrβ is required for embryonic specification and confinement of the adult white adipose lineage
    1
    1. scibot 20 Jan 2024
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      DOI: 10.1016/j.isci.2023.108682

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792241/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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      DOI: 10.1016/j.isci.2023.108733

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transforming growth factor-β1 protects against white matter injury and reactive astrogliosis via the p38 MAPK pathway in rodent demyelinating model
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    1. scibot 13 Jan 2024
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      DOI: 10.1111/jnc.16037

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16037
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    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
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    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.mce.2023.112140

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    sciencedirect.com/science/article/pii/S0303720723002915
  28. Dec 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation
    1
    1. scibot 28 Dec 2023
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      DOI: 10.4103/1673-5374.385310

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749609/
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    Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
    1
    1. scibot 23 Dec 2023
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      DOI: 10.1016/j.isci.2023.108691

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    An oncogenic phenoscape of colonic stem cell polarization
    2
    1. scibot 17 Dec 2023
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    sciencedirect.com/science/article/pii/S0092867423012217
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    Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses
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    sciencedirect.com/science/article/pii/S0092867423012205
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2666379123004974
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    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
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      DOI: 10.1016/j.celrep.2023.113506

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    sciencedirect.com/science/article/pii/S2211124723015188
  35. Nov 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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      DOI: 10.1186/s40779-023-00494-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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      DOI: 10.1186/s12885-023-11612-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10644579/
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    Exosomes derived from platelet-rich plasma promote diabetic wound healing via the JAK2/STAT3 pathway
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    sciencedirect.com/science/article/pii/S2589004223023131
  39. Oct 2023
  40. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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      DOI: 10.1016/j.cmet.2023.09.012

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    sciencedirect.com/science/article/pii/S1550413123003686
  41. 52.53.155.43 52.53.155.43
    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    1. scibot 14 Oct 2023
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      DOI: 10.1101/2023.06.15.545148

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    52.53.155.43/3932de370933c2759897a986a0751f177eee572e/2023.06.15.545148v1.full-html.html
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    High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription
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      DOI: 10.1016/j.chom.2023.09.003

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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
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    The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
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  148. Dec 2021
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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  157. Oct 2021
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    Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity
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    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice
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  162. Sep 2021
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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    KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats
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  166. Aug 2021
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    Breast tumor kinase (Brk/PTK6) mediates advanced cancer phenotypes via SH2-domain dependent activation of RhoA and aryl hydrocarbon receptor (AhR) signaling
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    Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
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  179. Jul 2021
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    Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats
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    Peripheral Nerve Injury Triggers Neuroinflammation in the Medial Prefrontal Cortex and Ventral Hippocampus in a Subgroup of Rats with Coincident Affective Behavioural Changes
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    OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain
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    New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
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  187. www.sciencedirect.com www.sciencedirect.com
    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
    1
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      Phospho-p38 MAPK (Thr180/Tyr182) (D3F9) XPu00a0Rabbit mAb

      DOI: 10.1016/j.immuni.2019.03.005

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  188. www.cell.com www.cell.com
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  190. link.springer.com link.springer.com
    Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells
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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3
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    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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    Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
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  195. Jun 2021
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    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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    Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
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    Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
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  200. May 2021
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    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
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    Combined inhibition of histone deacetylases and BET family proteins as epigenetic therapy for nerve injury-induced neuropathic pain
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    Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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  207. Apr 2021
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    Discovery of Covalent MKK4/7 Dual Inhibitor
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    Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation
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    Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies
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  212. Mar 2021
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    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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    The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity
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    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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    PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity
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    Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
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  219. Jan 2021
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    Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington’s Disease Model
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      anti-Phospho-p38 MAPK (Thr180/Tyr182)

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    Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers
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  223. Dec 2020
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    FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
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  225. Oct 2020
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    Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
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    Sphingosylphosphorylcholine alleviates hypoxia-caused apoptosis in cardiac myofibroblasts via CaM/p38/STAT3 pathway
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    Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae
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    The p38 signaling pathway mediates the TGF‐β1‐induced increase in type I collagen deposition in human granulosa cells
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  230. Sep 2020
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    TGFβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration
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    Arctigenin protects mice from thioglycollate‐induced acute peritonitis
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