279 Matching Annotations
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    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
  3. Jun 2024
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    Minocycline Abrogates Individual Differences in Nerve Injury-Evoked Affective Disturbances in Male Rats and Prevents Associated Supraspinal Neuroinflammation
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    Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice
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    SARS-CoV-2 envelope protein regulates innate immune tolerance
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    GLUT2 regulation of p38 MAPK isoform protein expression and p38 phosphorylation in male versus female rat hypothalamic primary astrocyte Cultures
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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  9. May 2024
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    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    Host-pathogen Coadaptation by running with PAR protein
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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    sciencedirect.com/science/article/pii/S1934590924001292
  16. Apr 2024
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    Lysosomal dysfunction by inactivation of V-ATPase drives innate immune response in C. elegans
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    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    SWI/SNF complex-mediated chromatin remodelling in Candida glabrata promotes immune evasion
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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  26. Mar 2024
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    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
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    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
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  31. 52.53.155.43 52.53.155.43
    NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38MAPK/MK2 phosphorylation in S. Typhimurium infection
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  32. Feb 2024
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    Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1
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    sciencedirect.com/science/article/abs/pii/S1550413124000147
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
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    Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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  40. Jan 2024
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    Pdgfrβ is required for embryonic specification and confinement of the adult white adipose lineage
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    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca2+/Hh signaling pathway
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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    IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins
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    CAR-T cells targeting HLA-G as potent therapeutic strategy for EGFR mutated and overexpressed oral cancer
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  108. Jan 2023
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    Multi-omics profiling visualizes dynamics of cardiac development and functions
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    Pacritinib Inhibition of IRAK1 Blocks Aberrant TLR8 Signalling by SARS-CoV-2 and HIV-1-Derived RNA
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    Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model
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    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
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    BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1
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  139. Jun 2022
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    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
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  141. journals.lww.com journals.lww.com
    Muse cells decrease the neuroinflammatory response by... : Neural Regeneration Research
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
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  143. May 2022
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    SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production
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    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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    Dual HDAC/BRD4 Inhibitors Relieves Neuropathic Pain by Attenuating Inflammatory Response in Microglia After Spared Nerve Injury
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  147. Apr 2022
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    The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets
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    In situ synthesis and unidirectional insertion of membrane proteins in liposome-immobilized silica stationary phase for rapid preparation of microaffinity chromatography
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    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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    The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
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  152. Mar 2022
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    Bone erosion in inflammatory arthritis is attenuated by Trichinella spiralis through inhibiting M1 monocyte/macrophage polarization
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    Crry silencing alleviates Alzheimer’s disease injury by regulating neuroinflammatory cytokines and the complement system
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  158. Feb 2022
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    Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress
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    Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation
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    Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins
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    Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
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  164. Jan 2022
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    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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  166. Dec 2021
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    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
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    Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
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    The spike protein of SARS-CoV-2 virus induces heme oxygenase-1: Pathophysiologic implications
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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  171. Nov 2021
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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  175. Oct 2021
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    Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity
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    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice
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  180. Sep 2021
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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    KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    Breast tumor kinase (Brk/PTK6) mediates advanced cancer phenotypes via SH2-domain dependent activation of RhoA and aryl hydrocarbon receptor (AhR) signaling
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    Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
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    Peripheral Nerve Injury Triggers Neuroinflammation in the Medial Prefrontal Cortex and Ventral Hippocampus in a Subgroup of Rats with Coincident Affective Behavioural Changes
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    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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      Phospho-p38 MAPK (Thr180/Tyr182) (D3F9) XPu00a0Rabbit mAb

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    Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells
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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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    IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3
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    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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    Combined inhibition of histone deacetylases and BET family proteins as epigenetic therapy for nerve injury-induced neuropathic pain
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    Discovery of Covalent MKK4/7 Dual Inhibitor
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    Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation
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