204 Matching Annotations
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    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    sciencedirect.com/science/article/pii/S0092867424013242
  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11617384/
  5. Nov 2024
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    Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S0925443924005660
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    Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
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    sciencedirect.com/science/article/pii/S1535610824003969
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    β2-integrins control HIF1α activation in human neutrophils
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    pmc.ncbi.nlm.nih.gov/articles/PMC11513320/
  9. Oct 2024
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    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  11. Sep 2024
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    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
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    H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response
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    sciencedirect.com/science/article/pii/S2211124724010374
  15. Aug 2024
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    Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC
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    1. scibot 29 Aug 2024
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    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
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  18. Jul 2024
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    Protocol for constructing tumor-targeting ANM-PROTACs for degradation of transcription factors
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    sciencedirect.com/science/article/pii/S266616672400385X
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    Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner
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    sciencedirect.com/science/article/pii/S2211124724008714
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    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
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    sciencedirect.com/science/article/pii/S1074761324002796
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    Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication
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  23. 52.53.155.43 52.53.155.43
    cir-23-0666-html.html
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Combination of ß-Hydroxybutyrate and Citrate Ameliorates Disease Progression in a Rat Model of Polycystic Kidney Disease
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  25. Jun 2024
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    De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency
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    STAT3 drives the expression of ACSL4 in acute kidney injury
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  28. May 2024
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    Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
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    sciencedirect.com/science/article/pii/S2451945624001818
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    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
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    The adipose-neural axis is involved in epicardial adipose tissue-related cardiac arrhythmias
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  34. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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  35. Apr 2024
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    Repurposing AS1411 for constructing ANM-PROTACs
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    sciencedirect.com/science/article/pii/S2451945624001272
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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    sciencedirect.com/science/article/pii/S2666379124001666
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    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
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    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973142/
  40. Mar 2024
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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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    sciencedirect.com/science/article/pii/S2211124724003309
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    Mecp2 knock-out astrocytes affect synaptogenesis by Interleukin 6 dependent mechanisms
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
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    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
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    sciencedirect.com/science/article/pii/S1534580724000765
  45. Feb 2024
  46. www.sciencedirect.com www.sciencedirect.com
    The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes
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    sciencedirect.com/science/article/pii/S2211124724001414
  47. 52.53.155.43 52.53.155.43
    can-22-3965-html.html
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    52.53.155.43/b267fbdd19a530509c54979d05951e91bb2c0d21/3693-html.html
  48. www.biorxiv.org www.biorxiv.org
    A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression
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      DOI: 10.1101/2024.02.14.580367

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    biorxiv.org/content/10.1101/2024.02.14.580367v1
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10854367/
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    Transcription factor ZNF263 enhances EGFR-targeted therapeutic response and reduces residual disease in lung adenocarcinoma
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    Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs
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  53. Jan 2024
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    Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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    Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells
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  60. Dec 2023
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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  64. Nov 2023
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    Exosomes derived from platelet-rich plasma promote diabetic wound healing via the JAK2/STAT3 pathway
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    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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  70. Oct 2023
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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    Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
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    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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    Inhibition of SOCS3 signaling in the nucleus tractus solitarii and retrotrapezoid nucleus alleviates hypoventilation in diet-induced obese male mice
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    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
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    N-arachidonylglycine is a caloric state-dependent circulating metabolite which regulates human CD4+ T cell responsiveness.
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    Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3
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  151. Sep 2021
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    Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
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    Transcriptional control of brain tumor stem cells by a carbohydrate binding protein
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  154. Aug 2021
  155. www.sciencedirect.com www.sciencedirect.com
    ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis
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  156. academic.oup.com academic.oup.com
    Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPKα Signaling in Male Offspring of Obese Dams
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  157. www.mdpi.com www.mdpi.com
    The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells
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  158. www.jneurosci.org www.jneurosci.org
    Pen-2 negatively regulates the differentiation of oligodendrocyte precursor cells into astrocytes in the central nervous system
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      DOI: 10.1523/JNEUROSCI.2455-19.2021

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  159. www.nature.com www.nature.com
    Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
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  160. Jul 2021
  161. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  162. www.sciencedirect.com www.sciencedirect.com
    Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
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      Mouse monoclonal anti-STAT3

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  163. www.sciencedirect.com www.sciencedirect.com
    The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3
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  164. www.sciencedirect.com www.sciencedirect.com
    CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota
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      Stat3 mouse mAb (124H6)

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  165. www.nature.com www.nature.com
    Treatment of type 2 diabetes with the designer cytokine IC7Fc
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      total STAT3

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  166. www.sciencedirect.com www.sciencedirect.com
    Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease
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  167. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Human Breast Cancer Xenograft Model Implicates Peroxisome Proliferator–activated Receptor Signaling as Driver of Cancer-induced Muscle Fatigue
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  168. www.sciencedirect.com www.sciencedirect.com
    Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
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      DOI: 10.1016/j.celrep.2018.10.063

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  169. www.sciencedirect.com www.sciencedirect.com
    Modest enhancement of sensory axon regeneration in the sciatic nerve with conditional co-deletion of PTEN and SOCS3 in the dorsal root ganglia of adult mice
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      RRID:AB_10694804

      DOI: 10.1016/j.expneurol.2018.02.012

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  170. www.sciencedirect.com www.sciencedirect.com
    Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells
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      RRID:AB_10694804

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    Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway
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      AB_331757

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  172. Jun 2021
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
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      RRID:AB_331757

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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis
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    Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling
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  176. May 2021
  177. www.nature.com www.nature.com
    Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure
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      DOI: 10.1038/s41398-021-01421-8

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  178. www.sciencedirect.com www.sciencedirect.com
    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
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    Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors
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    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
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  182. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Binge‐Like Ethanol Drinking Activates ALK Signaling and Increases the Expression of STAT3 Target Genes in the Mouse Hippocampus and Prefrontal Cortex
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    Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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  185. Apr 2021
  186. www.sciencedirect.com www.sciencedirect.com
    HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins
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    sciencedirect.com/science/article/pii/S2451945620303846
  187. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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      RRID:AB_331757

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    cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
  188. Feb 2021
  189. www.sciencedirect.com www.sciencedirect.com
    The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation
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  190. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  191. www.mdpi.com www.mdpi.com
    Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes
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      DOI: 10.3390/antiox10020334

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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer
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  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glucocorticoids attenuate interleukin‐6‐induced c‐Fos and Egr1 expression and impair neuritogenesis in PC12 cells
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching
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  195. www.embopress.org www.embopress.org
    STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer
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    CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci
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    A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling
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    Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons
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    Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease
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    Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells
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  229. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    Mutations in Craniosynostosis Patients Cause Defective Interleukin-11 Receptor Maturation and Drive Craniosynostosis-like Disease in Mice
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    Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity
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    Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses
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    Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization
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    IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure
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    Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT‐1 by a Notch‐dependent mechanism
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      RRID:AB_331757
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14135/full