763 Matching Annotations
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    A distal promoter and aberrant splicing enable canonical translation of out-of-frame proteins in Huntington’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12633298/
  3. Nov 2025
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    SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis
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    Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope
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    sciencedirect.com/science/article/pii/S1097276525008688
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    H2BK120ub and its reader RNF169 sequentially regulate replication fork remodeling and stability
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    DIRAS3-derived cyclic peptides disrupt KRAS-RAF interaction and KRAS nanoclustering, suppressing KRAS-driven pancreatic and ovarian tumors
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    iGlucoSnFR2: A genetically encoded fluorescent sensor for measuring intracellular or extracellular glucose in vivo in mouse brain
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    KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C
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    CRISPR live-cell imaging reveals chromatin dynamics and enhancer interactions at multiple non-repetitive loci
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    WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair
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    Phospho-proteome profiling in human neurons reveals targets of TBK1 in ALS/FTD-associated autophagy networks
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  13. Oct 2025
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    VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair
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    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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    Protocol for image-based monitoring of de novo RNA synthesis at DNA double-strand breaks in human cell lines
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    TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidification
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    A guide to selecting high-performing antibodies for VCP (UniProt ID: P55072) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12547379/
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    Visualizing PINK1 Activity Dynamics in Single Cells with a Phase Separation-Based Kinase Activity Reporter
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    biorxiv.org/content/10.1101/2025.10.08.681260v2
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    Gene Delivery Mediated by Backbone-Degradable RAFT Copolymers
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    MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death
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    BRIGHT Enables High-SNR Live-Cell Imaging of Non-Repetitive Sequences via Bivalent Fluorescent Nanobody-Mediated Cascade-Dependent Illumination
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    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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  28. Sep 2025
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    PhenoModel: A multimodal phenotypic drug design foundation model for discovering novel potential inhibitors of multiple cancer cells
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    ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains
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  41. Aug 2025
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    AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance
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  65. Jul 2025
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    A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells
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    Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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  84. Jun 2025
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    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells
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    Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics
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    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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