742 Matching Annotations
  1. Oct 2025
  2. www.sciencedirect.com www.sciencedirect.com
    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    sciencedirect.com/science/article/pii/S2211124725011799
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    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
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    Targeted citrullination enables p53 binding to non-canonical sites
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    sciencedirect.com/science/article/pii/S1097276525007452
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    CXCL10-induced chemotaxis of ex vivo-expanded natural killer cells combined with NKTR-255 enhances anti-tumor efficacy in osteosarcoma
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    sciencedirect.com/science/article/pii/S2950329925001201
  6. Sep 2025
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    PhenoModel: A multimodal phenotypic drug design foundation model for discovering novel potential inhibitors of multiple cancer cells
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    The kinesin motor Kif9 regulates centriolar satellite positioning during interphase
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    ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains
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  10. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    PPM1D is directly degraded by proteasomes in a ubiquitination-independent manner through its carboxyl-terminal region
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    Protocol for multiplexed transcription factor activity detection using optimized barcoded reporters and an automated computational pipeline
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    Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis
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    elifesciences.org/reviewed-preprints/105209
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    LAT1-Targeted Alpha Therapy Using 211At-AAMT for Bone and Soft Tissue Sarcomas
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    A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance
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    Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response
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    Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis
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  17. www.biorxiv.org www.biorxiv.org
    Cyclin-dependent kinase-like 5 (CDKL5) binds to talin and is anchored at the postsynaptic density via direct interaction with PDZ domains
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    Pharmacologic interrogation of USP28 cellular function in p53 signaling
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  19. Aug 2025
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    Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection
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    TRF1 and TRF2 form distinct shelterin subcomplexes at telomeres
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    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    Co-translational ribosome pairing enables native assembly of misfolding-prone subunits
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    Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
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    AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance
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    Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma
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    A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance
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    Design of soluble Notch agonists that drive T cell development and boost immunity
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  43. Jul 2025
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    Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling
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  46. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease
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    A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics
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    The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation
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    A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells
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    Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments
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    Proteasome-dependent Orc6 removal from chromatin upon S-phase entry safeguards against minichromosome maintenance complex reloading and tetraploidy
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    Protocol for induction and study of DNA double-strand breaks in mammalian cells using PALM microdissection and expansion microscopy
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    Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study
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    Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
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    Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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  62. Jun 2025
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    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells
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    Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis
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    Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics
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  75. May 2025
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    Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells
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    Catalytic-Dependent Role of DNA Polymerase κ in Nucleotide Excision Repair
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    Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics
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  89. Apr 2025
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    Aberrant phase separation drives membranous organelle remodeling and tumorigenesis
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    Loss of function of Atrx recapitulates phenotypes of alternative lengthening of telomeres in a primary mouse model of sarcoma
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    RNF144A-VRK2-G3BP1 axis regulates stress granule assembly
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  190. www.sciencedirect.com www.sciencedirect.com
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  194. www.cell.com www.cell.com
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  196. bio-protocol.org bio-protocol.org
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  197. Jul 2024
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  199. www.biorxiv.org www.biorxiv.org
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  207. academic.oup.com academic.oup.com
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  208. journals.asm.org journals.asm.org
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  209. Jun 2024
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  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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