902 Matching Annotations
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  2. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70720
  3. Sep 2026
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    KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution
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    link.springer.com/article/10.1038/s44318-026-00891-0
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70333
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    Integrative proteomics defines FANCA as a multifunctional hub linking DNA repair to translation
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    sciencedirect.com/science/article/pii/S2589004226028397
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    Epitranscriptomic silencing of STK25 promotes ferroptosis evasion via the METTL3–YAP–GPX4 axis in osteosarcoma
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    sciencedirect.com/science/article/pii/S0304383526005719
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic Targeting of Protein Complexes with Molecular COUPLrs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13527781/
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    Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC13523465/
  10. Aug 2026
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    CDC7 and APC/CCdh1 gate distinct routes to initiate DNA replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC13507225/
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    CDT1 acts with the replisome to remodel replication forks
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    science.org/doi/10.1126/sciadv.aee6914
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    Constitutive macropinocytosis sustains the inflammatory phenotype of senescent cells
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    biorxiv.org/content/10.64898/2026.07.12.738086v1
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70705
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    Ldha Regulates Osteosarcoma Lung Metastasis through Hedgehog Signaling
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    aacrjournals.org/cancerrescommun/article/6/6/1495/786203/Ldha-Regulates-Osteosarcoma-Lung-Metastasis
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    MITF maintains genome stability in nonmelanocyte lineages
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    pmc.ncbi.nlm.nih.gov/articles/PMC13398355/
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    Translation-driven temporal control for intertwined protein assembly
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    biorxiv.org/content/10.1101/2025.08.25.672138v1
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    Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death
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    pmc.ncbi.nlm.nih.gov/articles/PMC13401815/
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    Biomimetic multistage drug delivery system for reversing chemoresistance in osteosarcoma
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    sciencedirect.com/science/article/pii/S1385894726075273
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    Schlafen 11 (SLFN11) is overexpressed in multiple myeloma and undergoes nucleolar translocation in response to bortezomib
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402946/
  21. Jul 2026
  22. www.science.org www.science.org
    NDRG1 expression in cancers confers dependence on DNA damage repair and sensitivity to quinacrine
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    science.org/doi/10.1126/scisignal.adv4272
  23. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α-Mangostin: A Structure–Activity Relationship Insight
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cfch.202500045
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    A guide to selecting high-performing antibodies for Netrin-1 (UniProt ID: O95631) for use in western blot and immunoprecipitation
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    f1000research.com/articles/15-1129
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    CIP2A recruits SLX4-MUS81-XPF in mitosis and protects against replication stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC13354792/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ANXA3 activates HIF-1α/VEGF Signaling Via the PI3K/AKT/mTOR Pathway to Promote Osteosarcoma Stem Cell-Like Phenotype
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    A Lentiviral Fluorescent Reporter to Study Circadian Rhythms in Single Cells
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    Progerin-induced nuclear envelope remodeling is shaped by cell division and NUP153
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    PARG regulates the proteasomal degradation of TARG1
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    DDX3 Regulates the Innate Immune Response to Bone Sarcomas
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    biorxiv.org/content/10.64898/2026.07.01.735844v1
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    Prognostic characteristics of disulfidptosis-related genes across cancers and their potential implications in osteosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13319833/
  32. Jun 2026
  33. www.biorxiv.org www.biorxiv.org
    ER-Lysosome Cholesterol Exchange Regulates Lysosomal Motility Through mTOR-Dependent LAMTOR1 Phosphorylation
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    biorxiv.org/content/10.64898/2026.03.31.715514v1
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    Progerin-Induced Nuclear Envelope Remodeling is Shaped by Cell Division and NUP153
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    biorxiv.org/content/10.64898/2026.01.23.701344v1
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    Tumor-educated macrophages promote cytokine-driven lung colonization in triple-negative breast cancer
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    Centrosome linker protein CEP68 modulates cellular stress responses via nuclear condensate formation and HSP27 interaction
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    sciencedirect.com/science/article/pii/S2589004226018663
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    ABL kinase-dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70398
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    La Crosse virus, but not Jamestown Canyon virus, is dependent on the host translation termination factor eRF1 due to changes in the nonstructural protein NSm
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    journals.asm.org/doi/10.1128/mbio.01046-26
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    Mitochondrial degradation of metallothionein enables local zinc mobilization during zinc limitation
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    biorxiv.org/content/10.64898/2026.06.09.731205v1
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    Structural Mechanism and Cellular Restriction of Tau Seeding from Endolysosomes
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    ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation
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    IntAct-U-ExM enables super-resolution imaging of isoform-specific actin networks across species
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    CPSF2-mediated 3’ UTR truncation of MTERF3 drives mitochondrial dysfunction and osteosarcoma progression
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    nature.com/articles/s41388-026-03855-0
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    DNA replication stress and translational repression converge to drive CDK1- and caspase-dependent apoptosis in Ewing sarcoma
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    R-PLA enables enhanced detection of R-loops in mammalian cells using proximity ligation
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    Deep learning of functional perturbations from condensate morphology
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    The molecular architecture of tunneling nanotubes
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    biorxiv.org/content/10.64898/2026.05.27.728322v1
  48. May 2026
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    Mechanism of RACK1-dependent ZAKα activation at stalled and collided ribosomes
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    sciencedirect.com/science/article/pii/S1097276526002881
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    Actin isoform–specific interactions revealed by Vibrio VopV actin-binding repeats
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    pmc.ncbi.nlm.nih.gov/articles/PMC12685140/
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    The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179060/
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    Murine Embryonic Stem Cells Possess Distinct E2F Activity That Activates Tumor Suppressor Promoter Elements
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    onlinelibrary.wiley.com/doi/10.1111/gtc.70121
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    Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects
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    Combined Inhibition of ATR and Ribonucleotide Reductase Induces Synergistic Antineoplastic Activity in Osteosarcoma Cells
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    onlinelibrary.wiley.com/doi/10.1002/cnr2.70568
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ASCC3 promotes chemosensitivity in colorectal cancer cells
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  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel potent and selective GCN2 inhibitor, APL-4098, has anti-leukemic activity through dysregulation of mitochondrial function
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133605/
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    Click-code-seq reveals strand biases of DNA oxidation and depurination in human genome
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  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoclonal Antibodies Accessing the Cytosol of Living Cells and Binding to Polo‐Like Kinase 1 Interdomain Linker Affect Mitotic Behavior
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    pmc.ncbi.nlm.nih.gov/articles/PMC13127698/
  62. Apr 2026
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    The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK
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    Overexpression generates aberrant distribution of endocytic regulators - the case of the Rab11/LAMP1 compartment
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    Structural basis for ADAM17 activation by the iRhom1 pseudoprotease
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    sciencedirect.com/science/article/pii/S2211124726003876
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    Activation of T cell-intrinsic p53 by acetylation elicits antitumor immunity to boost cancer immunotherapy
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    Endoglin-directed CAR-T cells Comprehensively Target Tumors in Advanced Sarcomas
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    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
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    Proteomic Profiling Reveals How Physiological Media Reshape Cancer Cell Proteomes and Signaling Networks
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    RPA hyperphosphorylation hinders the resolution of R-loops and G-quadruplex-associated R-loops during RAS-driven senescence
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    The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity
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    A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance
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    Structure-Guided Synthetic Peptide Targeting Nucleolus and Neural Progenitor Protein Nuclear Import Impairs Ribosome Biogenesis and Cancer Cell Proliferation
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202500799
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    Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
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    The ATRXt Protein Represses rDNA Transcription While Mirroring ATRX Interactions and Heterochromatin Localization
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    The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
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    Unveiling the molecular architecture of T cells and immune synapses with cryo-expansion microscopy
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  83. Mar 2026
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    Shear stress-induced Piezo1 activates CD99L2 to facilitate the initiation of blood circulation
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    Specific GPCRs elicit unique extracellular vesicle miRNA array signatures
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    Fucoxanthin, a bioactive compound derived from edible seaweed, supports proteostasis and protects against stress and senescence
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    sciencedirect.com/science/article/pii/S096399692600671X
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    Microhomology-mediated end joining acts directly on replication forks to repair single-ended double-strand breaks
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    sciencedirect.com/science/article/pii/S1097276526001309
  88. www.biorxiv.org www.biorxiv.org
    Membrane Curvature Activates Src kinase and Promotes Metastatic Cancer Cell Survival
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    biorxiv.org/content/10.64898/2026.03.03.709279v1
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    A cellular basis for the mammalian nocturnal-diurnal switch
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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target
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    onlinelibrary.wiley.com/doi/10.1111/acel.70434
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    MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes
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    Ski2-like helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses
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    sciencedirect.com/science/article/pii/S2211124726001294
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    ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition
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