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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A
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    1. scibot 21 Dec 2024
      ATCCHTB-96

      DOI: 10.1016/j.molcel.2024.11.034

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    sciencedirect.com/science/article/pii/S1097276524009894
  3. jhoonline.biomedcentral.com jhoonline.biomedcentral.com
    Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells
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    1. scibot 21 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1186/s13045-024-01641-7

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    jhoonline.biomedcentral.com/articles/10.1186/s13045-024-01641-7
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZBTB48 is a priming factor regulating B-cell-specific CIITA expression
    1
    1. scibot 21 Dec 2024
      CVCL_0042

      DOI: 10.1038/s44318-024-00306-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11649694/
  5. Dec 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy
    2
    1. scibot 14 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.isci.2024.111384

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    2. scibot 14 Dec 2024
      CVCL_0042

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    pmc.ncbi.nlm.nih.gov/articles/PMC11634986/
  7. www.sciencedirect.com www.sciencedirect.com
    PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress
    1
    1. scibot 14 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.celrep.2024.115066

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    sciencedirect.com/science/article/pii/S2211124724014177
  8. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 13 Dec 2024
      RRID: CVCL_0042

      DOI: 10.1002/1878-0261.13773

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13773
  9. www.sciencedirect.com www.sciencedirect.com
    Circular RNAs trigger nonsense-mediated mRNA decay
    1
    1. scibot 12 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.molcel.2024.11.022

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    sciencedirect.com/science/article/pii/S109727652400947X
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
    1
    1. scibot 11 Dec 2024
      RRID: CVCL_0042

      DOI: 10.1158/2767-9764.CRC-24-0316

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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  11. www.sciencedirect.com www.sciencedirect.com
    Optimized reporters for multiplexed detection of transcription factor activity
    1
    1. scibot 10 Dec 2024
      ATCCCat#HTB-96, RRID:CVCL_0042

      DOI: 10.1016/j.cels.2024.11.003

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    sciencedirect.com/science/article/pii/S2405471224003120
  12. www.sciencedirect.com www.sciencedirect.com
    Dual BACH1 regulation by complementary SCF-type E3 ligases
    1
    1. scibot 10 Dec 2024
      ATCCCat# HTB-96

      DOI: 10.1016/j.cell.2024.11.006

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    sciencedirect.com/science/article/pii/S0092867424013229
  13. www.sciencedirect.com www.sciencedirect.com
    Reactive oxygen species control protein degradation at the mitochondrial import gate
    1
    1. scibot 06 Dec 2024
      ATCCCat# HTB-96

      DOI: 10.1016/j.molcel.2024.11.004

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    sciencedirect.com/science/article/pii/S1097276524009092
  14. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
    1
    1. scibot 05 Dec 2024
      ATCCHTB-96

      DOI: 10.1016/j.molcel.2024.11.009

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    sciencedirect.com/science/article/pii/S1097276524009146
  15. www.sciencedirect.com www.sciencedirect.com
    The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma
    1
    1. scibot 05 Dec 2024
      RRID:HTB-96

      DOI: 10.1016/j.celrep.2024.115035

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    sciencedirect.com/science/article/pii/S221112472401386X
  16. www.nature.com www.nature.com
    ChromEMT: visualizing and reconstructing chromatin ultrastructure and 3D organization in situ
    1
    1. scibot 03 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1038/s41596-024-01071-2

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    nature.com/articles/s41596-024-01071-2
  17. www.sciencedirect.com www.sciencedirect.com
    Nuclear Factor I family members are key transcription factors regulating gene expression
    1
    1. scibot 02 Dec 2024
      HTB-96

      DOI: 10.1016/j.mcpro.2024.100890

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    sciencedirect.com/science/article/pii/S1535947624001804
  18. www.sciencedirect.com www.sciencedirect.com
    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
    1
    1. scibot 02 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.molcel.2024.10.044

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    sciencedirect.com/science/article/pii/S1097276524008840
  19. www.sciencedirect.com www.sciencedirect.com
    Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain
    1
    1. scibot 02 Dec 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.celrep.2024.115016

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    sciencedirect.com/science/article/pii/S2211124724013676
  20. Nov 2024
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
    1
    1. scibot 21 Nov 2024
      RRID:CVCL_0042

      DOI: 10.1038/s44318-024-00240-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  22. www.sciencedirect.com www.sciencedirect.com
    The molecular chaperone ALYREF promotes R-loop resolution and maintains genome stability
    1
    1. scibot 14 Nov 2024
      92022711

      DOI: 10.1016/j.jbc.2024.107996

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    sciencedirect.com/science/article/pii/S0021925824024980
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
    1
    1. scibot 07 Nov 2024
      RRID:CVCL_0042

      DOI: 10.1158/1535-7163.MCT-23-0487

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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  24. www.nature.com www.nature.com
    Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins
    1
    1. scibot 07 Nov 2024
      RRID:CVCL_0042

      DOI: 10.1038/s41596-024-01075-y

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    nature.com/articles/s41596-024-01075-y
  25. Oct 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Moesin contributes to heat shock gene response through direct binding to the Med15 subunit of the Mediator complex in the nucleus
    1
    1. scibot 04 Oct 2024
      RRID:CVCL_0042

      DOI: 10.1098/rsob.240110

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    ncbi.nlm.nih.gov/pmc/articles/PMC11444770/
  27. www.sciencedirect.com www.sciencedirect.com
    Pervasive mislocalization of pathogenic coding variants underlying human disorders
    1
    1. scibot 02 Oct 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.cell.2024.09.003

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    sciencedirect.com/science/article/pii/S0092867424010213
  28. Sep 2024
  29. www.nature.com www.nature.com
    Rapid generation of homozygous fluorescent knock-in human cells using CRISPR–Cas9 genome editing and validation by automated imaging and digital PCR screening
    1
    1. scibot 28 Sep 2024
      RRID:CVCL_0042

      DOI: 10.1038/s41596-024-01043-6

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    nature.com/articles/s41596-024-01043-6
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand
    1
    1. scibot 26 Sep 2024
      RRID:CVCL_0042

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    ncbi.nlm.nih.gov/pmc/articles/PMC11416401/
  31. www.sciencedirect.com www.sciencedirect.com
    A TBK1-independent primordial function of STING in lysosomal biogenesis
    1
    1. scibot 25 Sep 2024
      Cat#HTB-96

      DOI: 10.1016/j.molcel.2024.08.026

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    sciencedirect.com/science/article/pii/S1097276524007032
  32. elifesciences.org elifesciences.org
    A mechanism in Agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome
    1
    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.7554/eLife.49180

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      Curator comments: HEK293T Cell Line ATCC Cat# CRL-3216

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    elifesciences.org/articles/49180
  33. elifesciences.org elifesciences.org
    Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice
    1
    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.7554/eLife.45303

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    elifesciences.org/articles/45303
  34. elifesciences.org elifesciences.org
    Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria
    1
    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.7554/eLife.34836

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    elifesciences.org/articles/34836
  35. www.sciencedirect.com www.sciencedirect.com
    C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function
    1
    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.molcel.2019.03.019

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    sciencedirect.com/science/article/pii/S1097276519302230
  36. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.cell.2018.09.057

      Resource: (BCRC Cat# 60094, RRID:CVCL_0224)

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    sciencedirect.com/science/article/pii/S0092867418313084
  37. europepmc.org europepmc.org
    Untitled document
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    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.7554/eLife.34836

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      Curator comments: ATCC Cat# CRL-1573, HEK293 cell line

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    europepmc.org/articles/PMC5957528/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 25 Sep 2024
      RRID:CVCL_0042

      DOI: 10.7554/eLife.34836

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    ncbi.nlm.nih.gov/pmc/articles/PMC5957528/
  39. www.sciencedirect.com www.sciencedirect.com
    Protocol to study the direct binding of proteins to RNA:DNA hybrids or RNA-DNA chimeras in living cells using cross-linking immunoprecipitation
    1
    1. scibot 16 Sep 2024
      RRID: CVCL_0042

      DOI: 10.1016/j.xpro.2024.103292

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      DOI:10.1016/j.xpro.2024.103292 RRID:CVCL_0042
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    sciencedirect.com/science/article/pii/S266616672400457X
  40. www.sciencedirect.com www.sciencedirect.com
    A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein
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    1. scibot 13 Sep 2024
      RRID: HTB-96

      DOI: 10.1016/j.celrep.2024.114727

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    sciencedirect.com/science/article/pii/S2211124724010787
  41. www.sciencedirect.com www.sciencedirect.com
    Conserved cysteine-switches for redox sensing operate in the Cyclin-Dependent Kinase Inhibitor p21(CIP/KIP) Protein Family.
    1
    1. scibot 13 Sep 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.freeradbiomed.2024.09.013

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    sciencedirect.com/science/article/pii/S0891584924006609
  42. www.sciencedirect.com www.sciencedirect.com
    A compact, versatile drug-induced splicing switch system with minimal background expression
    1
    1. scibot 05 Sep 2024
      HTB-96

      DOI: 10.1016/j.crmeth.2024.100842

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    sciencedirect.com/science/article/pii/S2667237524002157
  43. Aug 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells
    1
    1. scibot 22 Aug 2024
      U2OS

      DOI: 10.1007/s00018-024-05380-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11335261/
  45. www.sciencedirect.com www.sciencedirect.com
    Condensate interfacial forces reposition DNA loci and probe chromatin viscoelasticity
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    1. scibot 22 Aug 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.cell.2024.07.034

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    sciencedirect.com/science/article/pii/S0092867424008286
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
    1
    1. scibot 22 Aug 2024
      RRID:CVCL_0042

      DOI: 10.1128/mbio.01117-24

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    ncbi.nlm.nih.gov/pmc/articles/PMC11323502/
  47. www.sciencedirect.com www.sciencedirect.com
    Optogenetic control of kinesin-1, -2, -3 and dynein reveals their specific roles in vesicular transport
    1
    1. scibot 22 Aug 2024
      RRID:CVCL_0042

      DOI: 10.1016/j.celrep.2024.114649

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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    Structural requirements for activity of Mind bomb1 in Notch signaling
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    RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes
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    Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay
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    Neotelomeres and telomere-spanning chromosomal arm fusions in cancer genomes revealed by long-read sequencing
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling
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  55. www.sciencedirect.com www.sciencedirect.com
    Generation of densely labeled oligonucleotides for the detection of small genomic elements
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis
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  57. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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  58. www.science.org www.science.org
    Posttranslational modification of microtubules by the MATCAP detyrosinase
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  59. www.cell.com www.cell.com
    Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin
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  60. www.mdpi.com www.mdpi.com
    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
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  61. bio-protocol.org bio-protocol.org
    Protocol for Establishing a Multiplex Image-based Autophagy ...
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  62. Jul 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the main barriers to Ku accumulation in chromatin
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  64. www.biorxiv.org www.biorxiv.org
    Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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  66. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    AXIN2 promotes degradation of AXIN1 through tankyrase in colorectal cancer cells
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Miga-mediated endoplasmic reticulum–mitochondria contact sites regulate neuronal homeostasis
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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  72. academic.oup.com academic.oup.com
    A RAD18–UBC13–PALB2–RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells
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  73. journals.asm.org journals.asm.org
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
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  74. Jun 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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  76. www.nature.com www.nature.com
    An intermediate Rb–E2F activity state safeguards proliferation commitment
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection
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  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A comparative analysis of paxillin and Hic-5 proximity interactomes
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  82. www.sciencedirect.com www.sciencedirect.com
    Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
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  83. May 2024
  84. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Doxorubicin induces deglycosylation of cancer cell-intrinsic PD-1 by NGLY1
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  85. www.biorxiv.org www.biorxiv.org
    Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis
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    mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
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    TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
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  88. www.sciencedirect.com www.sciencedirect.com
    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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  89. 52.53.155.43 52.53.155.43
    Centriolar satellites are sites of translation of centrosomal and ciliary proteins
    1
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      RRID:CVCL_0042

      DOI: 10.1101/2024.02.22.581531

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  90. journals.biologists.com journals.biologists.com
    Ferroptosis induces membrane blebbing in placental trophoblasts
    1
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      U2OS

      DOI: 10.1242/jcs.255737

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    journals.biologists.com/jcs/article/135/5/jcs255737/224124/Ferroptosis-induces-membrane-blebbing-in-placental
  91. 52.53.155.43 52.53.155.43
    Intracellular delivery of oncolytic viruses with engineered Salmonella causes viral replication and cell death
    1
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      DOI: 10.1016/j.isci.2024.109813

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    52.53.155.43/6ccee77371dd354552d7d5ac3781151e9655f8d3/PIIS2589004224010356-html.html
  92. www.sciencedirect.com www.sciencedirect.com
    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
    1
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      DOI: 10.1016/j.ebiom.2024.105124

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    sciencedirect.com/science/article/pii/S2352396424001592
  93. www.sciencedirect.com www.sciencedirect.com
    A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture
    1
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      DOI: 10.1016/j.cub.2024.04.028

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    sciencedirect.com/science/article/pii/S0960982224004688
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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      DOI: 10.1093/nar/gkae120

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039982/
  95. Apr 2024
  96. www.sciencedirect.com www.sciencedirect.com
    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells
    1
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      ATCCHTB-96

      DOI: 10.1016/j.molcel.2024.04.004

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  97. www.sciencedirect.com www.sciencedirect.com
    TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
    1
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      HTB-96

      DOI: 10.1016/j.cmet.2024.04.003

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    sciencedirect.com/science/article/pii/S1550413124001232
  98. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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      DOI: 10.1158/1541-7786.MCR-23-0676

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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
  99. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
    1
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      RRID: CVCL_0042

      DOI: 10.1038/s44318-024-00038-z

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  100. www.sciencedirect.com www.sciencedirect.com
    DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
    1
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      HTB-96

      DOI: 10.1016/j.cels.2024.03.003

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  101. www.biorxiv.org www.biorxiv.org
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
    1
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      DOI: 10.1101/2024.04.07.588476

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    biorxiv.org/content/10.1101/2024.04.07.588476v1
  102. www.sciencedirect.com www.sciencedirect.com
    Time-series reconstruction of the molecular architecture of human centriole assembly
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      HTB-96

      DOI: 10.1016/j.cell.2024.03.025

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    sciencedirect.com/science/article/pii/S0092867424003167
  103. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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      DOI: 10.1002/1878-0261.13645

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13645
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
    1
    1. scibot 10 Apr 2024
      ATCCCat# HTB-96

      DOI: 10.1016/j.isci.2024.109524

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993188/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TDP-43 deficiency in Suprachiasmatic Nucleus perturbs rhythmicity of neuroactivity in Prefrontal Cortex
    2
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      RRID:HTB-96

      DOI: 10.1016/j.isci.2024.109522

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      RRID:HTB-96

      DOI: 10.1016/j.isci.2024.109522

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    ncbi.nlm.nih.gov/pmc/articles/PMC10995886/
  106. www.sciencedirect.com www.sciencedirect.com
    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
    1
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      HTB-96

      DOI: 10.1016/j.molcel.2024.03.011

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  107. www.sciencedirect.com www.sciencedirect.com
    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
    1
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      RRID:CVCL_0042

      DOI: 10.1016/j.devcel.2024.03.014

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    sciencedirect.com/science/article/pii/S1534580724001801
  108. www.sciencedirect.com www.sciencedirect.com
    Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
    1
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      RRID:CVCL_0042

      DOI: 10.1016/j.devcel.2024.03.021

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    sciencedirect.com/science/article/pii/S1534580724001898
  109. Mar 2024
  110. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
    1
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      RRID:CVCL_0042

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  111. www.sciencedirect.com www.sciencedirect.com
    Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin
    1
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      DOI: 10.1016/j.str.2024.02.022

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    sciencedirect.com/science/article/pii/S0969212624000820
  112. www.sciencedirect.com www.sciencedirect.com
    Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
    1
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      DOI: 10.1016/j.celrep.2024.113965

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    sciencedirect.com/science/article/pii/S2211124724002936
  113. www.sciencedirect.com www.sciencedirect.com
    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
    1
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      RRID:CVCL_0042

      DOI: 10.1016/j.molcel.2024.02.029

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    sciencedirect.com/science/article/pii/S1097276524001722
  114. 52.53.155.43 52.53.155.43
    The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling
    3
    1. scibot 19 Mar 2024
      RRID:CVCL_0042

      DOI: 10.1038/s44319-023-00035-z

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      RRID:CVCL_0042

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      RRID:CVCL_0042

      DOI: 10.1038/s44319-023-00035-z

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    52.53.155.43/85f3cfb5ea69a502f1e71c384533cb9dacfc2966/collin-et-al-2024-the-immediate-early-protein-1-of-human-herpesvirus-6b-interacts-with-nbs1-and-inhibits-atm-signaling-html.html
  115. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
    2
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      RRID:CVCL_0042

      DOI: 10.1038/s44318-024-00038-z

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      RRID:CVCL_0042

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    embopress.org/doi/full/10.1038/s44318-024-00038-z
  116. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
    1
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      RRID:CVCL_0042

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  117. www.sciencedirect.com www.sciencedirect.com
    HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
    1
    1. scibot 12 Mar 2024
      ATCCHTB-96™

      DOI: 10.1016/j.celrep.2024.113788

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen
    1
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      RRID:CVCL_0042

      DOI: 10.1083/jcb.202306048

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  119. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
    2
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      RRID:CVCL_0042

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      RRID:CVCL_0042

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  120. www.sciencedirect.com www.sciencedirect.com
    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
    2
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      RRID:CVCL_0042

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      RRID:CVCL_0042

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses
    1
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      ATCCHTB-96

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    ncbi.nlm.nih.gov/pmc/articles/PMC11019558/
  122. Feb 2024
  123. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
    1
    1. scibot 29 Feb 2024
      ATCCCat#HTB-96

      DOI: 10.1016/j.molcel.2024.02.002

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    sciencedirect.com/science/article/pii/S1097276524000984
  124. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
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      CVCL_0042

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  125. 52.53.155.43 52.53.155.43
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
    1
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      RRID:CVCL_0042

      DOI: 10.1101/2023.09.27.559698

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  126. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
    1
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
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      CVCL_0042

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  128. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses
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      DOI: 10.1002/ijc.34883

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  129. www.biorxiv.org www.biorxiv.org
    Circadian period is compensated for repressor protein turnover rates in single cells
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  130. www.sciencedirect.com www.sciencedirect.com
    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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      HTB-96, ATCC

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  131. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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  132. www.biorxiv.org www.biorxiv.org
    qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes.
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  133. www.sciencedirect.com www.sciencedirect.com
    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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  134. www.sciencedirect.com www.sciencedirect.com
    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
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  135. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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  136. Jan 2024
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MCAK Inhibitors Induce Aneuploidy in Triple-Negative Breast Cancer Models
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress
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  139. www.science.org www.science.org
    SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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      RRID:CVCL_0042

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  141. www.sciencedirect.com www.sciencedirect.com
    p300 is an obligate integrator of combinatorial transcription factor inputs
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GRB2 is a BECN1 interacting protein that regulates autophagy.
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of TNFRSF21 as an inhibitory factor of osteosarcoma based on a necroptosis-related prognostic gene signature and molecular experiments
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      DOI: 10.1186/s12935-023-03198-w

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  144. Dec 2023
  145. www.sciencedirect.com www.sciencedirect.com
    Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities
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      RRID:CVCL_0042

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  146. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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      ATCCCat# HTB-96

      DOI: 10.1016/j.cell.2023.11.022

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  147. www.sciencedirect.com www.sciencedirect.com
    u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions
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      RRID:CVCL_0042

      DOI: 10.1016/j.crmeth.2023.100655

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    sciencedirect.com/science/article/pii/S2667237523003260
  148. www.sciencedirect.com www.sciencedirect.com
    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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      ATCCCat# HTB-96

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    sciencedirect.com/science/article/pii/S2451945623004233
  149. www.sciencedirect.com www.sciencedirect.com
    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
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      RRID:CVCL_0042

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    sciencedirect.com/science/article/pii/S221112472301567X
  150. www.sciencedirect.com www.sciencedirect.com
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    sciencedirect.com/science/article/pii/S2211124723014249
  151. Nov 2023
  152. www.sciencedirect.com www.sciencedirect.com
    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
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    sciencedirect.com/science/article/pii/S1097276523008481
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    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    sciencedirect.com/science/article/pii/S1097276523008420
  154. www.sciencedirect.com www.sciencedirect.com
    Self-reversal facilitates the resolution of HMCES DNA-protein crosslinks in cells
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    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
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  156. www.sciencedirect.com www.sciencedirect.com
    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
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      RRID:CVCL_0042

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  157. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A genome-wide CRISPR screen identifies USP1 as a novel regulator of the mammalian circadian clock
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.16990
  158. www.biorxiv.org www.biorxiv.org
    Intermittent subdiffusion of short nuclear actin rods due to interactions with chromatin
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      DOI: 10.1101/2023.11.03.565456

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    biorxiv.org/content/10.1101/2023.11.03.565456v1
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
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  160. Oct 2023
  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma
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      DOI: 10.3390/cancers15204911

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  162. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
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  163. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
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    sciencedirect.com/science/article/pii/S1534580723004951
  164. www.sciencedirect.com www.sciencedirect.com
    Progesterone receptor membrane component 1 facilitates Ca2+ signal amplification between endosomes and the endoplasmic reticulum
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  165. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/7b3101f3d01462bbcf14399b3becbcb8b341bb38/Molecular Oncology - 2023 - Hsieh - Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer-html.html
  166. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Assessing the performance of the Cell Painting assay across different imaging systems
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
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      DOI: 10.1083/jcb.202303078

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  168. 52.53.155.43 52.53.155.43
    Preprints202309.2164.v1-html.html
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  169. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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  170. Sep 2023
  171. www.sciencedirect.com www.sciencedirect.com
    ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization
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    Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition
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  173. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
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  174. link.springer.com link.springer.com
    The ubiquitin specific protease 7 stabilizes HPV16E7 to promote HPV-mediated carcinogenesis
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  175. www.cell.com www.cell.com
    Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation
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  176. Aug 2023
  177. www.sciencedirect.com www.sciencedirect.com
    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
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  178. www.science.org www.science.org
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Charged multivesicular body protein 2b for use in Western Blot, immunoprecipitation and immunofluorescence
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  181. www.sciencedirect.com www.sciencedirect.com
    Developing a peptide to disrupt cohesin head domain interactions
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  182. www.nature.com www.nature.com
    Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor
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  183. 52.53.155.43 52.53.155.43
    crc-23-0268-html.html
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  184. www.science.org www.science.org
    SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
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  185. Jul 2023
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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  187. www.sciencedirect.com www.sciencedirect.com
    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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  188. www.sciencedirect.com www.sciencedirect.com
    Protocol for automated multivariate quantitative-image-based cytometry analysis by fluorescence microscopy of asynchronous adherent cells
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probing local chromatin dynamics by tracking telomeres
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma
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  191. www.sciencedirect.com www.sciencedirect.com
    A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma
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  192. Jun 2023
  193. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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  194. www.nature.com www.nature.com
    Optimizing the Cell Painting assay for image-based profiling
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  195. www.sciencedirect.com www.sciencedirect.com
    Bursting translation on single mRNAs in live cells
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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  197. www.sciencedirect.com www.sciencedirect.com
    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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  198. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
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      CVCL_0042

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    52.53.155.43/9bb0847614ccded1b0f58470978ac3d19ed6d9f2/c2b09516-8ba1-4604-955c-4ba2339bb68f_132628_-_kathleen_southern-html.html
  199. www.biorxiv.org www.biorxiv.org
    Illumina Dark Chemical Matter using the Cell Painting Assay
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    biorxiv.org/content/10.1101/2023.05.31.542818v1
  200. May 2023
  201. www.biorxiv.org www.biorxiv.org
    p300 Is an Obligate Integrator of Combinatorial Transcription Factor Inputs
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  202. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/1a559124e3edf90a3a192a434aa5ce7edc5188f8/Molecular Oncology - 2023 - Martinikova - PPM1D activity promotes the replication stress caused by cyclin E1 overexpression-html.html
  203. 52.53.155.43 52.53.155.43
    FEBS Press
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      DOI: 10.1002/1878-0261.13448

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    52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals
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  205. www.sciencedirect.com www.sciencedirect.com
    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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  206. www.sciencedirect.com www.sciencedirect.com
    Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma
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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH
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      RRID:CVCL_0042

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  208. www.sciencedirect.com www.sciencedirect.com
    Adherens junctions stimulate and spatially guide integrin activation and extracellular matrix deposition
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      ATCCHTB-96

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  209. Apr 2023
  210. www.biorxiv.org www.biorxiv.org
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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    Fanconi anemia-associated chromosomal radial formation is dependent on POLθ-mediated alternative end joining
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    1. scibot 26 Apr 2023
      RRID:CVCL_0042

      DOI: 10.1016/j.celrep.2023.112428

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    sciencedirect.com/science/article/pii/S2211124723004394
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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    1. scibot 21 Apr 2023
      RRID:CVCL_0042

      DOI: 10.1158/1078-0432.CCR-22-2977

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    1. scibot 20 Apr 2023
      RRID:CVCL_0042

      DOI: 10.1126/sciadv.ade7997

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    ncbi.nlm.nih.gov/pmc/articles/PMC10104471/
  214. www.science.org www.science.org
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
    1
    1. scibot 20 Apr 2023
      RRID:CVCL_0042

      DOI: 10.1126/sciadv.ade7997

      Resource: (CLS Cat# 300364/p489_U-2_OS, RRID:CVCL_0042)

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    science.org/doi/10.1126/sciadv.ade7997