610 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38
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    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114502

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    sciencedirect.com/science/article/pii/S2211124724008313
  3. Jul 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.jhazmat.2024.135105

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    sciencedirect.com/science/article/pii/S0304389424016844
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progression
    1
    1. scibot 04 Jul 2024
      RRID:SCR_000305

      DOI: 10.1083/jcb.202310022

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    ncbi.nlm.nih.gov/pmc/articles/PMC11215527/
  6. Jun 2024
  7. www.cell.com www.cell.com
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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    1. scibot 30 Jun 2024
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      DOI: 10.1016/j.isci.2024.110120

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    cell.com/iscience/abstract/S2589-0042(24)01345-2
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction
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    1. scibot 28 Jun 2024
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      DOI: 10.1002/advs.202307695

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    onlinelibrary.wiley.com/doi/10.1002/advs.202307695
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The clock gene BHLHE40 and atypical CCNG2 control androgen-induced cellular senescence as a novel tumor suppressive pathway in prostate cancer
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    1. scibot 27 Jun 2024
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      DOI: 10.1186/s13046-024-03097-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11188219/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The genomes of Dahlia pinnata, Cosmos bipinnatus, and Bidens alba in tribe Coreopsideae provide insights into polyploid evolution and inulin biosynthesis
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    1. scibot 22 Jun 2024
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      DOI: 10.1093/gigascience/giae032

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    ncbi.nlm.nih.gov/pmc/articles/PMC11170221/
  11. www.sciencedirect.com www.sciencedirect.com
    A metabolomics pipeline highlights microbial metabolism in bloodstream infections
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.035

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    sciencedirect.com/science/article/pii/S0092867424005798
  12. www.sciencedirect.com www.sciencedirect.com
    Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.str.2024.05.013

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    sciencedirect.com/science/article/pii/S0969212624001904
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PredCoffee: A binary classification approach specifically for coffee odor
    1
    1. scibot 14 Jun 2024
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      DOI: 10.1016/j.isci.2024.110041

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    ncbi.nlm.nih.gov/pmc/articles/PMC11167484/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted protein degradation systems to enhance Wnt signaling
    1
    1. scibot 13 Jun 2024
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      DOI: 10.7554/eLife.93908

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161174/
  15. www.sciencedirect.com www.sciencedirect.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.002

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    sciencedirect.com/science/article/pii/S0092867424004938
  16. May 2024
  17. www.sciencedirect.com www.sciencedirect.com
    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
    1
    1. scibot 31 May 2024
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      DOI: 10.1016/j.celrep.2024.114259

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    sciencedirect.com/science/article/pii/S2211124724005874
  18. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Two rare variants that affect the same amino acid in CFTR have distinct responses to ivacaftor
    1
    1. scibot 24 May 2024
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      DOI: 10.1113/JP285727

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285727
  19. www.biorxiv.org www.biorxiv.org
    Designing Combinatorial Multiepitope Vaccine Candidates against Scrub Typus by a Proteome-wide Immunoinfomatics Approach
    1
    1. scibot 24 May 2024
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      DOI: 10.1101/2024.03.05.583536

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    biorxiv.org/content/10.1101/2024.03.05.583536v1
  20. www.biorxiv.org www.biorxiv.org
    Generation of densely labeled oligonucleotides for the detection of small genomic elements
    1
    1. scibot 23 May 2024
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      DOI: 10.1101/2024.03.15.583980

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    biorxiv.org/content/10.1101/2024.03.15.583980v1
  21. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
    2
    1. scibot 23 May 2024
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      DOI: 10.1158/1541-7786.MCR-23-0109

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      DOI: 10.1158/1541-7786.MCR-23-0109

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    aacrjournals.org/mcr/article/22/3/227/734703/TNFRSF19-within-the-13q12-12-Risk-Locus-Functions
  22. www.sciencedirect.com www.sciencedirect.com
    The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.celrep.2024.114262

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    sciencedirect.com/science/article/pii/S2211124724005904
  23. www.sciencedirect.com www.sciencedirect.com
    Deep mutational scanning of hepatitis B virus reveals a mechanism for cis-preferential reverse transcription
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.cell.2024.04.008

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    sciencedirect.com/science/article/pii/S0092867424004033
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
    1
    1. scibot 04 May 2024
      RRID:SCR_000305

      DOI: 10.1158/0008-5472.CAN-23-2268

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  25. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 03 May 2024
      RRID:SCR_000305

      DOI: 10.7554/eLife.90683

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    elifesciences.org/articles/90683
  26. Apr 2024
  27. aacrjournals.org aacrjournals.org
    Osteosarcoma cells secrete CXCL14 that activates integrin α11β1 on fibroblasts to form a lung metastatic niche
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1158/0008-5472.CAN-23-1307

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    aacrjournals.org/cancerres/article/84/7/994/742036/Osteosarcoma-Cells-Secrete-CXCL14-That-Activates
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114035

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100771/
  29. Mar 2024
  30. www.thno.org www.thno.org
    Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
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    1. scibot 30 Mar 2024
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      DOI: 10.7150/thno.90322

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    thno.org/v14p0436.htm
  31. www.sciencedirect.com www.sciencedirect.com
    Flexible scaffold-based cheminformatics approach for polypharmacological drug design
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.034

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    sciencedirect.com/science/article/pii/S009286742400237X
  32. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.037

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    sciencedirect.com/science/article/pii/S1097276524001801
  33. www.sciencedirect.com www.sciencedirect.com
    Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.immuni.2024.03.001

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    sciencedirect.com/science/article/pii/S1074761324000979
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier
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    1. scibot 19 Mar 2024
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      DOI: 10.1186/s12987-024-00529-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10941402/
  35. www.sciencedirect.com www.sciencedirect.com
    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.035

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    sciencedirect.com/science/article/pii/S109727652400176X
  36. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
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    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.013

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      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  37. www.sciencedirect.com www.sciencedirect.com
    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
    1
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      DOI: 10.1016/j.immuni.2024.02.008

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    sciencedirect.com/science/article/pii/S1074761324000840
  38. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of the plant plastid-encoded RNA polymerase
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      DOI: 10.1016/j.cell.2024.01.026

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    sciencedirect.com/science/article/pii/S0092867424000631
  39. Feb 2024
  40. 52.53.155.43 52.53.155.43
    d4-html.html
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      DOI: 10.1158/1541-7786.mcr-23-0109

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    52.53.155.43/f092aa63506937030df3074397696edbfe46ccc6/d4-html.html
  41. link.springer.com link.springer.com
    Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Radix Paeoniae Rubra Against Glioma
    1
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      DOI: 10.1007/s12010-024-04887-6

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    link.springer.com/article/10.1007/s12010-024-04887-6
  42. www.sciencedirect.com www.sciencedirect.com
    Origin of eukaryotic-like Vps23 shapes an ancient functional interplay between ESCRT and ubiquitin system in Asgard archaea
    1
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      DOI: 10.1016/j.celrep.2024.113781

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    sciencedirect.com/science/article/pii/S2211124724001098
  43. link.springer.com link.springer.com
    Repositioning baloxavir marboxil as VISTA agonist that ameliorates experimental asthma
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    1. scibot 13 Feb 2024
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      DOI: 10.1007/s10565-024-09852-x

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    link.springer.com/article/10.1007/s10565-024-09852-x
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
    1
    1. scibot 11 Feb 2024
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      DOI: 10.1126/sciadv.adj8027

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    ncbi.nlm.nih.gov/pmc/articles/PMC10851258/
  45. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
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      DOI: 10.7554/eLife.39611

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    elifesciences.org/articles/39611
  46. Jan 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering paralog-specific PSD-95 recombinant binders as minimally interfering multimodal probes for advanced imaging techniques
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    1. scibot 24 Jan 2024
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      DOI: 10.7554/eLife.69620

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    Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46
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    Cadmium promotes the binding and centrosomal translocation of CCDC85C and PLK4 via ROS-GCLM pathway to trigger centrosome amplification in colon cancer cells
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    Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection
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    Reappraisal of the DNA phosphorothioate modification machinery: uncovering neglected functional modalities and identification of new counter-invader defense systems
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  52. Dec 2023
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    Epinephrine inhibits PI3Kα via the Hippo kinases
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    Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels
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    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
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    Evolution towards simplicity in bacterial small heat shock protein system
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  57. Nov 2023
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    Impact of Mutations Defining SARS-CoV-2 Omicron Subvariants BA.2.12.1 and BA.4/5 on Spike Function and Neutralization
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    The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus
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    STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts
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    Architecture of the bacteriophage lambda tail
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    Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP
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  64. Oct 2023
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    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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    Destruction of self-derived PAMP via T3SS2 effector VopY to subvert PAMP-triggered immunity mediates Vibrio parahaemolyticus pathogenicity
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    Evolution and functional role prediction of the CYP6DE and CYP6DJ subfamilies in Dendroctonus (Curculionidae: Scolytinae) bark beetles
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    Replenishing decoy extracellular vesicles inhibits phenotype remodeling of tissue-resident cells in inflammation-driven arthritis
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    Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK
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    A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody
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  71. Sep 2023
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  73. Aug 2023
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis
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    Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase
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    The design of functional proteins using tensorized energy calculations
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    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
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    A tetracationic porphyrin with dual anti-prion activity
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  81. Jul 2023
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    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
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    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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    Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest
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    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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  87. Jun 2023
  88. www.biorxiv.org www.biorxiv.org
    Cleaving DNA with DNA: cooperative tuning of structure and reactivity driven by copper ions
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    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
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    Belly roll, a GPI-anchored Ly6 protein, regulates Drosophila melanogaster escape behaviors by modulating the excitability of nociceptive peptidergic interneurons
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    HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery
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    Centromere/kinetochore is assembled through CENP-C oligomerization
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    3D-informed targeting of the Trop-2 signal-activation site drives selective cancer vulnerability
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  94. May 2023
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    The genomic landscape of sensitivity to arsenic trioxide uncovered by genome-wide CRISPR-Cas9 screening
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    Unanticipated broad phylogeny of BEN DNA-binding domains revealed by structural homology searches
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    Human gasdermin D and MLKL disrupt mitochondria, endocytic traffic and TORC1 signalling in budding yeast
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter
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    Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
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    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
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    An ABCC9 Missense Variant Is Associated with Sudden Cardiac Death and Dilated Cardiomyopathy in Juvenile Dogs
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    Examining asymmetric pairwise pre-reaction and transition states in enzymatic catalysis by molecular dynamics simulation and quantum mechanics/molecular mechanics calculation
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    BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses
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  105. Apr 2023
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    Entrectinib a Plausible Inhibitor for Osteopontin (SPP1) in Cervical Cancer—Integrated Bioinformatic Approach
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    Species-specific MARCO-alphavirus interactions dictate chikungunya virus viremia
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    Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
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  110. Mar 2023
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    New biochemistry in the Rhodanese-phosphatase superfamily: emerging roles in diverse metabolic processes, nucleic acid modifications, and biological conflicts
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    Structural features of the Notch ankyrin domain-Deltex WWE2 domain heterodimer determined by NMR spectroscopy and functional implications
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    Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
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    Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
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    Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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  117. Feb 2023
  118. www.sciencedirect.com www.sciencedirect.com
    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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    DYF-5/MAK–dependent phosphorylation promotes ciliary tubulin unloading
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
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    Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS
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    Cellular mechanism of action of forsythiaside for the treatment of diabetic kidney disease
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  124. Jan 2023
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    The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
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    Improved ANAP incorporation and VCF analysis reveal details of P2X7 current facilitation and a limited conformational interplay between ATP binding and the intracellular ballast domain
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canagliflozin promotes osteoblastic MC3T3-E1 differentiation via AMPK/RUNX2 and improves bone microarchitecture in type 2 diabetic mice
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  129. Dec 2022
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding
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  133. Nov 2022
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    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
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    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
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  137. rupress.org rupress.org
    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
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  138. Oct 2022
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    Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation
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  140. Sep 2022
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
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  142. www.mdpi.com www.mdpi.com
    Methyltransferases of Riboviria
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  143. Aug 2022
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    Protocol to study the oligomeric organization of single-span transmembrane peptides using molecular dynamics simulations
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    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vision-related convergent gene losses reveal SERPINE3’s unknown role in the eye
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  149. Jul 2022
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    Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms
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    Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes
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  154. journals.plos.org journals.plos.org
    Inhibition of histone H3-H4 chaperone pathways rescues C. elegans sterility by H2B loss
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    Rational exploration of fold atlas for human solute carrier proteins
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    The time-zero HSQC method improves the linear free energy relationship of a polypeptide chain through the accurate measurement of residue-specific equilibrium constants
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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    Mussel-inspired monomer – A new selective protease inhibitor against dentine collagen degradation
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    A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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  161. May 2022
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    Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events
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    The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels
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    Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody
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  165. Apr 2022
  166. journals.physiology.org journals.physiology.org
    Whole genome sequencing identifies a deletion mutation in the unknown-functional KCNG2 from familial sick sinus syndrome
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  167. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  168. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax
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    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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    Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis
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  172. Mar 2022
  173. www.sciencedirect.com www.sciencedirect.com
    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphosite-dependent Presentation of Dual Phosphorylated Peptides by MHC Class I Molecules
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of nanobodies neutralizing SARS-CoV-2 variants
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystals of TELSAM–target protein fusions that exhibit minimal crystal contacts and lack direct inter-TELSAM contacts
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    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and ion-release mechanism of PIB-4-type ATPases
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    Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
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    Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
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    Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
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    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
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  186. Feb 2022
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae
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    The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
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    Naegleria’s mitotic spindles are built from unique tubulins and highlight core spindle features
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  190. elifesciences.org elifesciences.org
    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
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      DOI: 10.7554/eLife.72908

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  191. Jan 2022
  192. link.springer.com link.springer.com
    Florigen and its homologs of FT/CETS/PEBP/RKIP/YbhB family may be the enzymes of small molecule metabolism: review of the evidence
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      DOI: 10.1186/s12870-022-03432-z

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  193. www.sciencedirect.com www.sciencedirect.com
    Structural basis of bacteriophage lambda capsid maturation
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  194. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel variants underlying autosomal recessive neurodevelopmental disorders with intellectual disability in Iranian consanguineous families
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    onlinelibrary.wiley.com/doi/full/10.1002/jcla.24241
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8758145/
  196. www.sciencedirect.com www.sciencedirect.com
    Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
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    sciencedirect.com/science/article/pii/S2211124721016879
  197. Dec 2021
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8651296/
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
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  200. Nov 2021
  201. www.sciencedirect.com www.sciencedirect.com
    Paratope states in solution improve structure prediction and docking
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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Orchestrated actin nucleation by the Candida albicans polarisome complex enables filamentous growth
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      DOI: 10.1074/jbc.RA120.013890

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  203. www.sciencedirect.com www.sciencedirect.com
    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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    sciencedirect.com/science/article/pii/S0969212621003725
  204. Oct 2021
  205. www.sciencedirect.com www.sciencedirect.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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    sciencedirect.com/science/article/pii/S2211124721013474
  206. www.sciencedirect.com www.sciencedirect.com
    Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel
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      DOI: 10.1016/j.neuron.2021.10.006

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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2
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  208. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A novel receptor for platelet-activating factor and lysophosphatidylcholine in Trypanosoma cruzi
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      DOI: 10.1111/mmi.14778

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    onlinelibrary.wiley.com/doi/10.1111/mmi.14778
  209. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TPRG1-AS1 induces RBM24 expression and inhibits liver cancer progression by sponging miR-4691-5p and miR-3659
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      DOI: 10.1111/liv.15026

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    onlinelibrary.wiley.com/doi/10.1111/liv.15026
  210. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Andrographolide prevents bone loss via targeting ERRalpha-regulated metabolic adaption of osteoclastogenesis
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      DOI: 10.1111/bph.15614

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  211. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression and distribution of synaptotagmin family members in the zebrafish retina
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      DOI: 10.1002/cne.25238

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    onlinelibrary.wiley.com/doi/10.1002/cne.25238
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural characterization of NrnC identifies unifying features of dinucleotidases
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      DOI: 10.7554/eLife.70146

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    ncbi.nlm.nih.gov/pmc/articles/PMC8492067/
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Arg-293 of Cryptochrome1 is responsible for the allosteric regulation of CLOCK-CRY1 binding in circadian rhythm
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      DOI: 10.1074/jbc.RA120.014333

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    ncbi.nlm.nih.gov/pmc/articles/PMC7863883/
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase
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      DOI: 10.1016/j.chembiol.2021.03.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC8473560/
  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the activation of human calcium-sensing receptor
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      DOI: 10.7554/eLife.68578

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    ncbi.nlm.nih.gov/pmc/articles/PMC8476121/
  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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      DOI: 10.7554/eLife.71474

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  217. Sep 2021
  218. elifesciences.org elifesciences.org
    Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
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      DOI: 10.7554/eLife.70372

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  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
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      DOI: 10.1016/j.celrep.2021.109754

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  220. www.sciencedirect.com www.sciencedirect.com
    Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation
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      DOI: 10.1016/j.celrep.2021.109734

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  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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      DOI: 10.1016/j.celrep.2021.109760

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  222. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of human mTOR complexes by DEPTOR
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      DOI: 10.7554/eLife.70871

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  223. www.sciencedirect.com www.sciencedirect.com
    A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites
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    sciencedirect.com/science/article/pii/S0969212621002562
  224. www.sciencedirect.com www.sciencedirect.com
    Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection
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      DOI: 10.1016/j.chom.2021.08.010

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  225. Aug 2021
  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simulating PIP2-Induced Gating Transitions in Kir6.2 Channels
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      DOI: 10.3389/fmolb.2021.711975

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  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
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      DOI: 10.7554/eLife.71220

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  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation
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      DOI: 10.7554/eLife.63505

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  229. link.springer.com link.springer.com
    An Insilico evaluation of phytocompounds from Albizia amara and Phyla nodiflora as cyclooxygenase-2 enzyme inhibitors
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      DOI: 10.1007/s40199-021-00408-6

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