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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Whole-genome re-sequencing of the Baikal seal and other phocid seals for a glimpse into their genetic diversity, demographic history, and phylogeny
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    1. scibot 22 Dec 2024
      RRID:SCR_006525

      DOI: 10.46471/gigabyte.142

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    pmc.ncbi.nlm.nih.gov/articles/PMC11602651/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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    1. scibot 21 Dec 2024
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      DOI: 10.1158/0008-5472.CAN-24-1703

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    pmc.ncbi.nlm.nih.gov/articles/PMC7617242/
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    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.031

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    sciencedirect.com/science/article/pii/S1097276524009560
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    Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.immuni.2024.11.007

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    sciencedirect.com/science/article/pii/S1074761324005223
  6. Dec 2024
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    Genomic insights into Neolithic founding paternal lineages around the Qinghai-Xizang Plateau using integrated YanHuang resource
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    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.isci.2024.111456

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    sciencedirect.com/science/article/pii/S258900422402683X
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination
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    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.celrep.2019.03.108

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    pmc.ncbi.nlm.nih.gov/articles/PMC6486480/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional annotation of regulatory elements in rainbow trout uncovers roles of the epigenome in genetic selection and genome evolution
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    1. scibot 13 Dec 2024
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      DOI: 10.1093/gigascience/giae092

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    pmc.ncbi.nlm.nih.gov/articles/PMC11629980/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Association of Tumor Mutational Burden and PD-L1 with the Efficacy of Pembrolizumab with or without Chemotherapy versus Chemotherapy in Advanced Urothelial Carcinoma
    1
    1. scibot 12 Dec 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609623/
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    Single chromatin fiber profiling and nucleosome position mapping in the human brain
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    1. scibot 06 Dec 2024
      RRID:SCR_006525

      DOI: 10.1016/j.crmeth.2024.100911

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    sciencedirect.com/science/article/pii/S2667237524003011
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    The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.molcel.2024.10.046

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    sciencedirect.com/science/article/pii/S1097276524008852
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    Nuclear Factor I family members are key transcription factors regulating gene expression
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.mcpro.2024.100890

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    sciencedirect.com/science/article/pii/S1535947624001804
  14. Nov 2024
  15. 52.53.155.43 52.53.155.43
    Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodeler
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    1. scibot 22 Nov 2024
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      DOI: 10.1016/j.cell.2024.09.007

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    52.53.155.43/81c2471a16469e31311fc23237dcd10bcf01c26f/PIIS0092867424010250-html.html
  16. 52.53.155.43 52.53.155.43
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    1. scibot 14 Nov 2024
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  17. 52.53.155.43 52.53.155.43
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    1. scibot 14 Nov 2024
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  18. 52.53.155.43 52.53.155.43
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    1. scibot 14 Nov 2024
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide mapping of native co-localized G4s and R-loops in living cells
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    1. scibot 08 Nov 2024
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      DOI: 10.7554/eLife.99026

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    ncbi.nlm.nih.gov/pmc/articles/PMC11469684/
  20. 52.53.155.43 52.53.155.43
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    1. scibot 08 Nov 2024
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  21. Oct 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis
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    1. scibot 05 Oct 2024
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      DOI: 10.7554/eLife.93975

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  23. 52.53.155.43 52.53.155.43
    Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodeler
    1
    1. scibot 02 Oct 2024
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiosensitizing Effect of PARP Inhibition on Chondrosarcoma and Chondrocyte Cells Is Dependent on Radiation LET
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    1. scibot 02 Oct 2024
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      DOI: 10.3390/biom14091071

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    ncbi.nlm.nih.gov/pmc/articles/PMC11429578/
  25. Sep 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A reference genome, mitochondrial genome and associated transcriptomes for the critically endangered swift parrot ( Lathamus discolor)
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    1. scibot 25 Sep 2024
      RRID:SCR_006525

      DOI: 10.12688/f1000research.144352.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11411239/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Proteogenomics of Prostate Cancer Radioresistance
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    1. scibot 25 Sep 2024
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      DOI: 10.1158/2767-9764.CRC-24-0292

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    ncbi.nlm.nih.gov/pmc/articles/PMC11411600/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common gene signature of the right ventricle in failing rat and human hearts
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    1. scibot 12 Sep 2024
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      DOI: 10.1038/s44161-024-00485-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11358011/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
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    1. scibot 12 Sep 2024
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      DOI: 10.1158/0008-5472.CAN-23-1878

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    ncbi.nlm.nih.gov/pmc/articles/PMC11372369/
  30. www.sciencedirect.com www.sciencedirect.com
    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114730

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    sciencedirect.com/science/article/pii/S2211124724010817
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
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    1. scibot 05 Sep 2024
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      DOI: 10.1158/1078-0432.CCR-23-3720

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    1. scibot 30 Aug 2024
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      DOI: 10.1158/2767-9764.CRC-24-0214

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  34. www.biorxiv.org www.biorxiv.org
    Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data
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    1. scibot 23 Aug 2024
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      DOI: 10.1101/2024.08.13.607784

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    biorxiv.org/content/10.1101/2024.08.13.607784v1
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.molcel.2024.07.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deciphering cancer genomes with GenomeSpy: a grammar-based visualization toolkit
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    1. scibot 19 Aug 2024
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      DOI: 10.1093/gigascience/giae040

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    ncbi.nlm.nih.gov/pmc/articles/PMC11299109/
  37. academic.oup.com academic.oup.com
    High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing
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      DOI: 10.1093/gigascience/giz108

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    academic.oup.com/gigascience/article-abstract/8/9/giz108/5560333
  38. Jul 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinship analysis and pedigree reconstruction by RAD sequencing in cattle
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
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  42. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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      DOI: 10.1016/j.immuni.2024.07.001

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    cell.com/immunity/fulltext/S1074-7613(24)00348-0
  43. www.cell.com www.cell.com
    Further evidence from DNAH12 supports favorable fertility outcomes of infertile males with dynein axonemal heavy chain gene family variants
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      DOI: 10.1016/j.isci.2024.110366

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    cell.com/iscience/abstract/S2589-0042(24)01591-8
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua
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      DOI: 10.1016/j.devcel.2020.02.004

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      DOI: 10.1016/j.devcel.2020.02.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7161736/
  45. Jun 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
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    1. scibot 27 Jun 2024
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      DOI: 10.1093/narcan/zcae028

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    ncbi.nlm.nih.gov/pmc/articles/PMC11195629/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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      DOI: 10.1158/2767-9764.CRC-22-0287

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    ncbi.nlm.nih.gov/pmc/articles/PMC11188873/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRTK: a platform agnostic toolkit for linked-read analysis of both human genome and metagenome
    1
    1. scibot 22 Jun 2024
      RRID:SCR_006

      DOI: 10.1093/gigascience/giae028

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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Post-meiotic mechanism of facultative parthenogenesis in gonochoristic whiptail lizard species
    1
    1. scibot 13 Jun 2024
      RRID:SCR_006525

      DOI: 10.7554/eLife.97035

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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors
    1
    1. scibot 07 Jun 2024
      RRID:SCR_006525

      DOI: 10.1158/2159-8290.CD-23-1060

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145176/
  51. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1186/s12943-024-02034-7

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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  52. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific effects of age and sex on human cortical neurons
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.neuron.2024.05.013

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  53. May 2024
  54. 52.53.155.43 52.53.155.43
    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
    2
    1. scibot 29 May 2024
      RRID:SCR_006525

      DOI: 10.1101/2024.03.08.583864

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  55. www.sciencedirect.com www.sciencedirect.com
    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.celrep.2024.114258

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  56. www.sciencedirect.com www.sciencedirect.com
    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.immuni.2024.04.026

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  57. www.biorxiv.org www.biorxiv.org
    Unraveling Genome- and Immunome-wide Genetic Diversity in Jaguars (Panthera onca): Implications for Targeted Conservation
    1
    1. scibot 17 May 2024
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      DOI: 10.1101/2024.05.06.592690

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  58. aacrjournals.org aacrjournals.org
    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
    1
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      RRID:SCR_006525

      DOI: 10.1158/1078-0432.CCR-23-2438

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    aacrjournals.org/clincancerres/article/30/10/2272/745168/Integrative-Molecular-Analyses-of-the-MD-Anderson
  59. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    2
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      RRID: SCR_006525

      DOI: 10.1016/j.cell.2024.04.023

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  60. elifesciences.org elifesciences.org
    Mono-methylated histones control PARP-1 in chromatin and transcription
    1
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      DOI: 10.7554/eLife.91482

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  61. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
    1
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  62. Apr 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
    1. scibot 30 Apr 2024
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      DOI: 10.21203/rs.3.rs-3943095/v1

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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic Engineering of Oral Keratinocytes to Establish In Vitro Oral Potentially Malignant Disease Models as a Platform for Treatment Investigation
    1
    1. scibot 29 Apr 2024
      RRID:SCR_006525

      DOI: 10.3390/cells13080710

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  65. elifesciences.org elifesciences.org
    Convergent epigenetic evolution drives relapse in acute myeloid leukemia
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    1. scibot 24 Apr 2024
      RRID:SCR_006525

      DOI: 10.7554/eLife.93019

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced bovine genome annotation through integration of transcriptomics and epi-transcriptomics datasets facilitates genomic biology
    1
    1. scibot 20 Apr 2024
      RRID:SCR_006525

      DOI: 10.1093/gigascience/giae019

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  67. www.sciencedirect.com www.sciencedirect.com
    No evidence for ac4C within human mRNA upon data reassessment
    1
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      RRID:SCR_006525

      DOI: 10.1016/j.molcel.2024.03.017

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    sciencedirect.com/science/article/pii/S1097276524002272
  68. academic.oup.com academic.oup.com
    Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups
    1
    1. scibot 18 Apr 2024
      RRID:SCR_006525

      DOI: 10.1093/gigascience/giae014

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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae014/7646332
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Beyond basics: Key mutation selection features for successful tumor-informed ctDNA detection
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      DOI: 10.1002/ijc.34964

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34964
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitive MRD detection from lymphatic fluid after surgery in HPV-associated oropharyngeal cancer
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1158/1078-0432.CCR-23-1789

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  71. Mar 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques
    1
    1. scibot 22 Mar 2024
      RRID:SCR_006525

      DOI: 10.1186/s12967-024-04869-6

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  73. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
    2
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      RRID:SCR_006525

      DOI: 10.1016/j.cmet.2024.02.009

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1158/2159-8290.CD-22-1297

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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
    1
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      DOI: 10.1158/2159-8290.CD-23-0954

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  76. Feb 2024
  77. 52.53.155.43 52.53.155.43
    delete 3-html.html
    2
    1. scibot 29 Feb 2024
      RRID:SCR_006525

      DOI: 10.1158/1078-0432.ccr-23-1789

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  78. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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  79. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
    1
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      DOI: 10.1158/2159-8290.CD-23-0456

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    aacrjournals.org/cancerdiscovery/article/14/1/104/732565/Early-Cancer-Detection-in-Li-Fraumeni-Syndrome
  80. 52.53.155.43 52.53.155.43
    can-23-1129-html.html
    1
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      SCR_006525

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  81. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
    1
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      DOI: 10.1101/2023.12.10.570854

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    biorxiv.org/content/10.1101/2023.12.10.570854v1
  82. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
    1
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      DOI: 10.1038/s41467-024-45067-8

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
    1
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      DOI: 10.1158/2767-9764.CRC-23-0382

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  84. Jan 2024
  85. www.sciencedirect.com www.sciencedirect.com
    Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy
    1
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      DOI: 10.1016/j.xcrm.2023.101383

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Near chromosome-level and highly repetitive genome assembly of the snake pipefish Entelurus aequoreus (Syngnathiformes: Syngnathidae)
    1
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      DOI: 10.46471/gigabyte.105

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
    1
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      DOI: 10.1101/2023.12.20.570481

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  88. elifesciences.org elifesciences.org
    Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells
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      DOI: 10.7554/eLife.87607

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  89. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
    1
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      DOI: 10.1158/0008-5472.CAN-23-1129

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  91. Dec 2023
  92. www.sciencedirect.com www.sciencedirect.com
    Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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  94. 52.53.155.43 52.53.155.43
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  95. www.medrxiv.org www.medrxiv.org
    Diverging the anthracycline class of anti-cancer drugs for superior survival of acute myeloid leukemia patients
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  96. 52.53.155.43 52.53.155.43
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  97. Nov 2023
  98. www.sciencedirect.com www.sciencedirect.com
    Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colour polymorphism associated with a gene duplication in male wood tiger moths
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  100. wellcomeopenresearch.org wellcomeopenresearch.org
    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer
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  102. www.sciencedirect.com www.sciencedirect.com
    Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure
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  103. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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  104. Oct 2023
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    Molecular and functional characterization of the Drosophila melanogaster conserved smORFome
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
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    CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoantigen targetability in progressive advanced melanoma
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas
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  111. 52.53.155.43 52.53.155.43
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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    Allele-specific regulatory effects on the pig transcriptome
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  114. Sep 2023
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    Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity
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    Integration of eQTL and machine learning to dissect causal genes with pleiotropic effects in genetic regulation networks of seed cotton yield
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  117. Aug 2023
  118. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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  119. 52.53.155.43 52.53.155.43
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct mechanisms of mismatch repair deficiency delineate two modes of response to PD-1 immunotherapy in endometrial carcinoma
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone variants shape chromatin states in Arabidopsis
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    Inhibition of DNMT1 methyltransferase activity via glucose-regulated O-GlcNAcylation alters the epigenome
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    Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases
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  124. Jul 2023
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    A new haplotype-resolved turkey genome to enable turkey genetics and genomics research
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  127. www.sciencedirect.com www.sciencedirect.com
    Title: TET1 Facilitates Specification of Early Human Lineages including Germ Cells
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      DOI: 10.1016/j.isci.2023.107191

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  128. Jun 2023
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of transcriptional regulatory variants in pig duodenum, liver, and muscle tissues
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      DOI: 10.1093/gigascience/giad042

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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line
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  131. elifesciences.org elifesciences.org
    Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing
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      DOI: 10.7554/eLife.86842

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    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
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      DOI: 10.1016/j.neuron.2023.05.006

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    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
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    Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the gut microbiota confers cisplatin resistance in epithelial ovarian cancer
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      DOI: 10.1158/0008-5472.CAN-22-0455

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  137. 52.53.155.43 52.53.155.43
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Efficacy and Whole Exome Sequencing of Liquid Biopsies in a Phase IB/II study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer
    1
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  139. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
    1
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      DOI: 10.1158/0008-5472.CAN-22-2045

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  140. www.sciencedirect.com www.sciencedirect.com
    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
    1
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  141. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
    1
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      DOI: 10.1016/j.cell.2023.05.003

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  142. May 2023
  143. www.biorxiv.org www.biorxiv.org
    A common gene signature of the right ventricle in failing rat and human hearts
    1
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      DOI: 10.1101/2023.05.16.540913

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    Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
    1
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      DOI: 10.1016/j.neuron.2023.04.025

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  145. www.nature.com www.nature.com
    Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
    1
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      DOI: 10.1038/s41467-023-38271-5

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  146. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
    1
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      DOI: 10.1002/advs.202206098

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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHD-associated enhancers shape human cardiomyocyte lineage commitment
    1
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple germline events contribute to cancer development in patients with Li-Fraumeni syndrome
    1
    1. scibot 04 May 2023
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  149. Apr 2023
  150. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
    1
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  151. www.biorxiv.org www.biorxiv.org
    A chromatin-associated regulator of RNA Polymerase III assembly at tRNA genes revealed by locus-specific proteomics
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      DOI: 10.1101/2023.04.17.534528

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  152. www.sciencedirect.com www.sciencedirect.com
    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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  153. link.springer.com link.springer.com
    Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways
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      DOI: 10.1038/s41598-023-33096-0

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  154. www.sciencedirect.com www.sciencedirect.com
    Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development
    1
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      RRID:SCR_006525

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  155. www.sciencedirect.com www.sciencedirect.com
    INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
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  156. www.sciencedirect.com www.sciencedirect.com
    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of Genomic Sequencing to Refine Patient Stratification for Adjuvant Therapy in Renal Cell Carcinoma
    1
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lineage-specific differences and regulatory networks governing human chondrocyte development
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      DOI: 10.7554/eLife.79925

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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asparagine starvation suppresses histone demethylation through iron depletion
    1
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  160. academic.oup.com academic.oup.com
    A chromosome-scale high-contiguity genome assembly of the cheetah (Acinonyx jubatus)
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      DOI: 10.1093/jhered/esad015

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    academic.oup.com/jhered/advance-article/doi/10.1093/jhered/esad015/7069302
  161. Mar 2023
  162. academic.oup.com academic.oup.com
    Resequencing of a Pekin duck breeding population provides insights into the genomic response to short-term artificial selection
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      DOI: 10.1093/gigascience/giad016

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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish
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      DOI: 10.46471/gigabyte.44

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  164. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the deep-sea coral Lophelia pertusa
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  166. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease
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  167. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards
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      DOI: 10.1016/j.neuron.2023.02.013

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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress
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      DOI: 10.7554/eLife.79511

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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomic and epigenomic analyses revealed that polycomb repressive complex 2 regulates not only developmental but also stress responsive metabolism in Brassica rapa
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      DOI: 10.3389/fpls.2023.1079218

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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
    1
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      DOI: 10.1158/2767-9764.CRC-22-0456

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  171. www.sciencedirect.com www.sciencedirect.com
    A cell-type-specific alternative splicing regulator shapes synapse properties in a trans-synaptic manner
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      DOI: 10.1016/j.celrep.2023.112173

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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic Resources for the North American Water Vole (Microtus richardsoni) and the Montane Vole (Microtus montanus)
    1
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      DOI: 10.46471/gigabyte.19

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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome assembly of the Atlantic chub mackerel (Scomber colias): a valuable teleost fishing resource
    1
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-quality draft genome for Melaleuca alternifolia (tea tree): a new platform for evolutionary genomics of myrtaceous terpene-rich species
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      DOI: 10.46471/gigabyte.28

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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The genome of a giant (trevally): Caranx ignobilis
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  176. Feb 2023
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
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      DOI: 10.3389/fimmu.2022.1097730

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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia-like behavior and reductions in excitatory synapses
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      DOI: 10.7554/eLife.75631

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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
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      DOI: 10.21037/tlcr-22-507

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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
    1
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      DOI: 10.1158/2643-3230.BCD-21-0160

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  181. Jan 2023
  182. www.nature.com www.nature.com
    Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics
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      DOI: 10.1038/s41698-023-00354-3

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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
    1
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating Tumor DNA in Stage III Colorectal Cancer, beyond Minimal Residual Disease Detection, toward Assessment of Adjuvant Therapy Efficacy and Clinical Behavior of Recurrences
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4+ T-cell Responses in Glioblastoma
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
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  190. 52.53.155.43 52.53.155.43
    An integrated SAGA and TFIID PIC assembly pathway selective for poised and induced promoters.
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  191. Dec 2022
  192. www.sciencedirect.com www.sciencedirect.com
    Protocol to analyze population structure and migration history based on human genome variation data
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  193. elifesciences.org elifesciences.org
    Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells
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  194. 52.53.155.43 52.53.155.43
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  195. Nov 2022
  196. aacrjournals.org aacrjournals.org
    Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma
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  197. www.sciencedirect.com www.sciencedirect.com
    Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing
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  198. academic.oup.com academic.oup.com
    Selection signatures in goats reveal a novel deletion mutant underlying cashmere yield and diameter
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  199. www.sciencedirect.com www.sciencedirect.com
    A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan
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  200. Oct 2022
  201. elifesciences.org elifesciences.org
    Little skate genome provides insights into genetic programs essential for limb-based locomotion
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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAG2 expression is associated with adverse survival outcomes and regulates cell phenotype in muscle-invasive bladder cancer
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  203. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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  204. Sep 2022
  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAG2 promotes the myelination transcriptional program in oligodendrocytes
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  206. link.springer.com link.springer.com
    Correction to: Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing
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      DOI: 10.1186/s13578-022-00843-1

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  207. www.sciencedirect.com www.sciencedirect.com
    Sublethal cytochrome c release generates drug-tolerant persister cells
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  208. Aug 2022
  209. www.sciencedirect.com www.sciencedirect.com
    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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  211. www.sciencedirect.com www.sciencedirect.com
    TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells
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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A limit on the evolutionary rescue of an Antarctic bacterium from rising temperatures
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      DOI: 10.1126/sciadv.abk3511

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  213. Jul 2022
  214. 52.53.155.43 52.53.155.43
    A chromosome-scale genome assembly of the okapi (Okapia johnstoni)
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      DOI: 10.1093/jhered/esac033

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  215. www.science.org www.science.org
    A limit on the evolutionary rescue of an Antarctic bacterium from rising temperatures
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  216. www.researchsquare.com www.researchsquare.com
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  217. www.sciencedirect.com www.sciencedirect.com
    Volatile profiles of commercial vetch prepared via different processing methods
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  218. Jun 2022
  219. aacrjournals.org aacrjournals.org
    Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
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      DOI: 10.1158/2767-9764.CRC-22-0124

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  220. aacrjournals.org aacrjournals.org
    Predictive markers of response to neoadjuvant durvalumab with nab-paclitaxel and dose dense doxorubicin/cyclophosphamide in basal-like triple negative breast cancer
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  221. elifesciences.org elifesciences.org
    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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      DOI: 10.7554/eLife.66909

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  222. www.sciencedirect.com www.sciencedirect.com
    EED is required for mouse primordial germ cell differentiation in the embryonic gonad
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  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
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  224. May 2022
  225. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development
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      DOI: 10.7554/eLife.77241

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  226. gigabytejournal.com gigabytejournal.com
    LT1, an ONT long-read-based assembly scaffolded with Hi-C data and polished with short reads
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      DOI: 10.46471/gigabyte.51

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