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Jun 2024
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Tensin 4 facilitates aerobic glycolysis, migration and invasion of colorectal cancer cells through the β‑catenin/c‑Myc signaling pathway

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  12259
  
  DOI: 10.3892/ol.2024.14489
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11176887/
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A targetable PRR11-DHODH axis drives ferroptosis- and temozolomide-resistance in glioblastoma

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  DOI: 10.1016/j.redox.2024.103220
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11179629/
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G6PD and ACSL3 are synthetic lethal partners of NF2 in Schwann cells

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ncbi.nlm.nih.gov/pmc/articles/PMC11180199/
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ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification

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ncbi.nlm.nih.gov/pmc/articles/PMC11178500/
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Golgi dispersal in cancer stem cells promotes chemoresistance of colorectal cancer via the Golgi stress response

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ncbi.nlm.nih.gov/pmc/articles/PMC11180190/
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SLO2.1/NALCN Functional Complex Activity in Mouse Myometrial Smooth Muscle Cells During Pregnancy

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  plasmid_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11160795/
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Mechanistic patterns and clinical implications of oncogenic tyrosine kinase fusions in human cancers

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ncbi.nlm.nih.gov/pmc/articles/PMC11178778/
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Highlights from MBoC Selection: SARS-CoV-2 Orf6 is positioned in the nuclear pore complex by Rae1 to inhibit nucleocytoplasmic transport

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  Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11151100/
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TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution

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1. scibot 15 Jun 2024
  
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  pMD2.G
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161796/
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Pure estrogen receptor antagonists potentiate capecitabine activity in ESR1-mutant breast cancer

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  DOI: 10.1038/s41523-024-00647-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11162492/
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Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres

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  DOI: 10.1093/nar/gkae251
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11162766/
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Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model

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ncbi.nlm.nih.gov/pmc/articles/PMC11164933/
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MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration

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  pMD2.G
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11167044/
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SARS-CoV-2 NSP5 antagonizes MHC II expression by subverting histone deacetylase 2

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  12259
  
  DOI: 10.1242/jcs.262172
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11166459/
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Transcriptional Synergy in Human Aortic Endothelial Cells is Vulnerable to Combination p300/CBP and BET Bromodomain Inhibition

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  12259
  
  DOI: 10.1016/j.isci.2024.110011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11167439/
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APOBEC3-related mutations in the spike protein-encoding region facilitate SARS-CoV-2 evolution

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  12,259
  
  DOI: 10.1016/j.heliyon.2024.e32139
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11168432/
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GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior

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  DOI: 10.1038/s41598-024-60052-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11169677/
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Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

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  DOI: 10.1038/s43018-023-00704-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11175596/
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Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics

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1. scibot 15 Jun 2024
  
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  pMD2.G
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11170328/
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The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation

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  Addgene_12259
  
  DOI: 10.1186/s13075-024-03350-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11165854/
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IL-6 promotes tumor growth through immune evasion but is dispensable for cachexia

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  DOI: 10.1038/s44319-024-00144-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11169252/
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Targeted sequencing for hereditary breast and ovarian cancer in BRCA1/2-negative families from the Lynch Memorial Biobank reveals complex genetic architecture and phenocopies

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  DOI: 10.1016/j.xhgg.2024.100306
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11166883/
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TPX2 overexpression promotes sensitivity to dasatinib in breast cancer by activating YAP transcriptional signaling

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ncbi.nlm.nih.gov/pmc/articles/PMC11161735/
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CRISPR-Cas9 editing of synaptic genes in human embryonic stem cells for functional analysis in induced human neurons

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  DOI: 10.1016/j.xpro.2024.103089
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11152723/
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Targeting dependency on a paralog pair of CBP/p300 against de-repression of KREMEN2 in SMARCB1-deficient cancers

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ncbi.nlm.nih.gov/pmc/articles/PMC11153594/
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Targeting the DYRK1A kinase prevents cancer progression and metastasis and promotes cancer cells response to G1/S targeting chemotherapy drugs

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ncbi.nlm.nih.gov/pmc/articles/PMC11153725/
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Prickle1‐driven basement membrane deposition of the iPSC‐derived embryoid bodies is separable from the establishment of apicobasal polarity

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  https://www.addgene.org/12259/
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11150132/
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Identification of an HLA-A*11:01-restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations

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  DOI: 10.1007/s00262-024-03729-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11150344/
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NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation

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  PMD2. G
  
  DOI: 10.1186/s13058-024-01847-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11155144/
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A Crosstalk between the Receptor Tyrosine Kinase-Like Orphan Receptors ROR1/2 and S1P Signaling Pathways in Lung Cancer

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  pMD2.G
  
  DOI: 10.31557/APJCP.2024.25.3.725
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11152407/
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Oncogenic Roles of Laminin Subunit Gamma‐2 in Intrahepatic Cholangiocarcinoma via Promoting EGFR Translation

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  pMD2.G
  
  DOI: 10.1002/advs.202309010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11151066/
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Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells

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  DOI: 10.1371/journal.pgen.1011293
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161071/
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FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma

1
1. scibot 09 Jun 2024
  
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  12259
  
  DOI: 10.1371/journal.pbio.3002621
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161053/
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Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration

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  DOI: 10.1038/s41593-024-01619-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11156585/
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Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of PTEN-null, BRAFV600E melanoma to BRAF/MEK inhibition

1
1. scibot 09 Jun 2024
  
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  plasmid_12259
  
  DOI: 10.3389/fonc.2024.1191217
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11159048/
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Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

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  DOI: 10.1038/s43018-023-00550-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10918623/
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Methods for investigating STAT3 regulation of lysosomal function in mammary epithelial cells

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  DOI: 10.1007/s10911-024-09563-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11102350/
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BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis

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1. scibot 07 Jun 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11106271/
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FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation and lethality in glioblastoma and other cancers

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  DOI: 10.1093/narcan/zcae021
  
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Targeting c‐Myc transactivation by LMNA inhibits tRNA processing essential for malate‐aspartate shuttle and tumour progression

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  pMD2G
  
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Deprivation of methionine inhibits osteosarcoma growth and metastasis via C1orf112-mediated regulation of mitochondrial functions

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  pMD2.G
  
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Priming with LSD1 inhibitors promotes the persistence and antitumor effect of adoptively transferred T cells

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Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

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LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition

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Interplay Between Intracellular Transport Dynamics and Liquid‒Liquid Phase Separation

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Modulation of Paracellular Permeability in SARS-CoV-2 Blood-to-Brain Transcytosis

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CXCL8 Knockout: A Key to Resisting Pasteurella multocida Toxin-Induced Cytotoxicity

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  DOI: 10.3390/ijms25105330
  
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Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors

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Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells

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  Plasmid_12259
  
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Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7

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CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma

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A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML

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The ribotoxic stress response drives UV-mediated cell death

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Small molecule conjugates with selective estrogen receptor β agonism promote anti-aging benefits in metabolism and skin recovery

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Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase

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  DOI: 10.1073/pnas.2403685121
  
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Synthetic protein circuits for programmable control of mammalian cell death

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A fluorescence‐based sensor for calibrated measurement of protein kinase stability in live cells

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CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling

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KLRG1 Cell Depletion as a Novel Therapeutic Strategy in Patients with Mature T-Cell Lymphoma Subtypes

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Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

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Disease-linked mutations in Munc18-1 deplete synaptic Doc2

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Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression

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Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2

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CircPIAS1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis via the miR-455-3p/NUPR1/FTH1 axis

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Ferredoxin 1: a gatekeeper in halting lung adenocarcinoma progression through activation of the GPRIN2 signaling pathway

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CCR5-overexpressing mesenchymal stem cells protect against experimental autoimmune uveitis: insights from single-cell transcriptome analysis

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Identification of a Fully Human Antibody VH Domain Targeting Anaplastic Lymphoma Kinase (ALK) with Applications in ALK-Positive Solid Tumor Immunotherapy

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Pseudorabies virus hijacks the Rab6 protein to promote viral assembly and egress

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Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking

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  DOI: 10.1371/journal.ppat.1012231
  
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Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta

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ePRINT: exonuclease assisted mapping of protein-RNA interactions

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  DOI: 10.1186/s13059-024-03271-1
  
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Carboplatin restricts peste des petits ruminants virus replication by suppressing the STING-mediated autophagy

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  DOI: 10.3389/fvets.2024.1383927
  
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Activation of Bivalent Gene POU4F1 Promotes and Maintains Basal‐like Breast Cancer

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Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress

1
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  DOI: 10.1016/j.isci.2024.109983
  
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NKX2-5 regulates vessel remodeling in scleroderma-associated pulmonary arterial hypertension

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Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism

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Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors

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Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease

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ATP6AP2, a regulator of LRP6/β-catenin protein trafficking, promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner

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Protocol for preclinical evaluation of locoregionally delivered CAR T cells in patient-derived xenograft models of brain tumors

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A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis

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FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation

1
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Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation

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TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery

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PIIS2162253124001161-html.html

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In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods

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KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy

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The β-arrestin1/endothelin axis bolsters ovarian fibroblast-dependent invadosome activity and cancer cell metastatic potential

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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

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Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

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journals.asm.org journals.asm.org

The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication

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  RRID:Addgene_12259
  
  DOI: 10.1128/mbio.00499-24
  
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Protocol for mass spectrometric profiling of lysine malonylation by lysine acetyltransferase in CRISPRi K562 cell lines

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eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer

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Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus

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Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma

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aacrjournals.org/cancerres/article/84/10/1570/745316/Bile-Acid-Metabolism-Mediates-Cholesterol
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Development of chromosome 1q+ specific treatment for highest risk pediatric posterior fossa ependymoma

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aacrjournals.org/clincancerres/article/30/8/1544/742119/Development-of-Chromosome-1q-Specific-Treatment
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NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth

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aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
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Tsyn-seq: a T cell synapse-based antigen identification platform

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Direct interrogation of context-dependent GPCR activity with a universal biosensor platform

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Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis

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SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production

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  DOI: 10.1016/j.stem.2024.04.023
  
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TCF19 promotes cell proliferation and tumor formation in lung cancer by activating the Raf/MEK/ERK signaling pathway

1
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  pMD2. G
  
  DOI: 10.1016/j.tranon.2024.101978
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11088346/
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TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia

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  pMD2.G
  
  DOI: 10.1038/s41467-024-48328-8
  
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FBXO22 is a potential therapeutic target for recurrent chondrosarcoma

1
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Cyclin‐dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration‐resistant prostate cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC11089090/
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Comparing chemical transfection, electroporation, and lentiviral vector transduction to achieve optimal transfection conditions in the Vero cell line

1
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  12,259
  
  DOI: 10.1186/s12860-024-00511-x
  
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CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1

1
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  DOI: 10.1038/s41598-024-61626-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11091187/
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PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling

1
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  pMD2.G
  
  DOI: 10.1186/s13046-024-03062-3
  
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Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2

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NPEPPS Is a Druggable Driver of Platinum Resistance

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Urolithin A Hijacks ERK1/2‐ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity

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Endocardial HDAC3 is required for myocardial trabeculation

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  DOI: 10.1038/s41467-024-48362-6
  
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Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response

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Shared and distinct mechanisms of UBA1 inactivation across different diseases

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Nanobody-based CAR NK cells for possible immunotherapy of MICA+ tumors

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CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair

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  Addgene_12
  
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Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers

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Large donor CRISPR for whole-CDS replacement of cell adhesion molecule LRRTM2

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mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

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Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes

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Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism

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linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability

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Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation

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CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity

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HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer

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Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer

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Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis

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Bottom-up reconstruction of functional Death Domain Signalosomes reveals a requirement for polymer stability and avidity

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Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

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  Addgene_12259
  
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Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

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  Addgene_12259
  
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Engineering lentivirus envelope VSV-G for liver targeted delivery of IDOL-shRNA to ameliorate hypercholesterolemia and atherosclerosis

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  pMD2.G
  
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Imaging CAR-NK cells targeted to HER2 ovarian cancer with human sodium-iodide symporter-based positron emission tomography

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Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells

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New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

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AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription

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  12259
  
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The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone-client manner

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Genomic context– and H2AK119 ubiquitination–dependent inheritance of human Polycomb silencing

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  DOI: 10.1126/sciadv.adl4529
  
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Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter

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  DOI: 10.1093/nar/gkae240
  
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The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes

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  DOI: 10.1128/mbio.03429-23
  
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The IL-6 signaling pathway contributes critically to the immunomodulatory mechanism of human decidua-derived mesenchymal stromal cells

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The phosphatidylinositol-5′ phosphatase synaptojanin1 limits integrin-mediated invasion of Staphylococcus aureus

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SP2509, a specific antagonist of LSD1, exhibits antiviral properties against Porcine epidemic diarrhea virus

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  pMD2.G
  
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EGCG Disrupts the LIN28B/Let-7 Interaction and Reduces Neuroblastoma Aggressiveness

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  DOI: 10.3390/ijms25094795
  
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CD133 Stimulates Cell Proliferation via the Upregulation of Amphiregulin in Melanoma

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  pMD2.G
  
  DOI: 10.3390/cells13090777
  
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An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation

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DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4

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Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer

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2024.02.09.579580v1.full-html.html

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ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models

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Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma

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Activating innate immune responses repolarizes hPSC-derived CAR macrophages to improve anti-tumor activity

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TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT

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Cell competition promotes metastatic intestinal cancer through a multistage process

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An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins

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The Disassociation of A3G-Related HIV-1 cDNA G-to-A Hypermutation to Viral Infectivity

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CLEC4D as a Novel Prognostic Marker Boosts the Proliferation and Migration of Gastric Cancer via the NF-κB/AKT Signaling Pathway

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The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex

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Circadian coupling of mitochondria in a deep-diving mammal

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Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)

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SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes

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Expression of nuclear receptor co‑activator 7 protein is associated with poor prognosis of breast cancer

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Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation

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Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer

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Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2

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The epigenetic regulators EP300/CREBBP represent promising therapeutic targets in MLL-rearranged acute myeloid leukemia

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Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells

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A Method for the Production of Recombinant VSVs with Confirmation of Biological Activity

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Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity

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Methyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition

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MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer

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The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

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Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas

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The RNA polymerase II general transcription factor TFIIB is a target for transcriptome control during cellular stress and viral infection

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BAG3 regulates cilia homeostasis of glioblastoma via its WW domain

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Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

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CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer

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Influenza Virus Reduces Ubiquitin E3 Ligase MARCH10 Expression to Decrease Ciliary Beat Frequency

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Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size

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Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists

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The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration

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sciencedirect.com/science/article/pii/S2211124724005059
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1

1
1. scibot 30 Apr 2024
  
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  12259
  
  DOI: 10.1101/2024.04.09.588557
  
  Resource: RRID:Addgene_12259
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030418/
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CK2α-mediated phosphorylation of GRP94 facilitates the metastatic cascade in triple-negative breast cancer

1
1. scibot 30 Apr 2024
  
  in Public
  
  pMD2.G
  
  DOI: 10.1038/s41420-024-01956-x
  
  Resource: RRID:Addgene_12259
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11035675/
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Temporal coordination of the transcription factor response to H2O2 stress

1
1. scibot 30 Apr 2024
  
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  12259
  
  DOI: 10.1038/s41467-024-47837-w
  
  Resource: RRID:Addgene_12259
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11039679/
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Ribosomal S6 kinase 2-forkhead box protein O4 signaling pathway plays an essential role in melanogenesis

1
1. scibot 30 Apr 2024
  
  in Public
  
  pMD2.G
  
  DOI: 10.1038/s41598-024-60165-9
  
  Resource: RRID:Addgene_12259
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043394/
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Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4

1
1. scibot 30 Apr 2024
  
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  12259
  
  DOI: 10.1093/nar/gkae025
  
  Resource: RRID:Addgene_12259
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11039999/
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CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer

1
1. scibot 30 Apr 2024
  
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  12259
  
  DOI: 10.1016/j.isci.2024.109676
  
  Resource: RRID:Addgene_12259
  
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  SciCrunch record: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
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Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer

1
1. scibot 30 Apr 2024
  
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  12259
  
  DOI: 10.1038/s42003-024-06190-w
  
  Resource: RRID:Addgene_12259
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043391/
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A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function

1
1. scibot 30 Apr 2024
  
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  RRID:Addgene_12259
  
  DOI: 10.1101/2024.04.02.587836
  
  Resource: RRID:Addgene_12259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
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Stepwise Stiffening/Softening of and Cell Recovery from Reversibly Formulated Hydrogel Double Networks

1
1. scibot 30 Apr 2024
  
  in Public
  
  Addgene_12259
  
  DOI: 10.1101/2024.04.04.588191
  
  Resource: RRID:Addgene_12259
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030224/

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