3,748 Matching Annotations
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    Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease
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    science.org/doi/10.1126/sciadv.ady1623
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670078/
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    KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133430/
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    Bioenergetic responses to β-adrenergic stimulation in beige adipocyte depend on actomyosin driven forces
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    biorxiv.org/content/10.1101/2025.11.26.690550v1
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    Interferon dependent immune memory during HSV-1 neuronal latency via increased H3K9me3 and restriction by ATRX
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    nature.com/articles/s41467-025-66477-2
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    Eph receptors activate myeloid checkpoint receptor LILRB5 to support tumor development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137008/
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    Protocol to track single-cell-derived clones using DNA barcoding combined with single-cell RNA sequencing
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    sciencedirect.com:5037/science/article/pii/S2666166725006355
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    NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA
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    sciencedirect.com:5037/science/article/pii/S1097276525009062
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    High-throughput mapping of modular regulatory domains in human RNA-binding proteins
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    sciencedirect.com:5037/science/article/pii/S2405471225002832
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    Targeting TET3 suppresses group 3 medulloblastoma stemness and progression via impairing hypomethylation of Otx2 super-enhancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005476
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    Membrane potential mediates the cellular response to mechanical pressure
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    sciencedirect.com:5037/science/article/pii/S009286742501253X
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    Human RAP2A homolog of the Drosophila asymmetric cell division regulator Rap2l targets the stemness of glioblastoma stem cells
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    elifesciences.org/articles/105690
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12662214/
  16. Nov 2025
  17. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy
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    sciencedirect.com:5037/science/article/pii/S0006295225008275
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    A Clickable CoQ Imaging Probe reveals that Cellular Uptake and Lysosomal Trafficking depend on CD36 and NPC1
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    sciencedirect.com:5037/science/article/pii/S2213231725004495
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-13 protects epithelial cells from SARS-CoV-2 infection by inhibiting ACE2-mediated virus binding and cell entry
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    pmc.ncbi.nlm.nih.gov/articles/PMC12643477/
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    Targeting peptide–MHC complexes with designed T cell receptors and antibodies
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    biorxiv.org/content/10.1101/2025.11.19.689381v1
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The oxidative modification of transcription factor FOXM1 by Peroxiredoxin1 facilitates DNA damage repair and cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616168/
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    Stimulator of interferon genes signaling network-driven prognostic signature for pancreatic cancer: Hub gene discovery with multimodal validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12598526/
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    TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF-κB pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594511/
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    HDAC11-Mediated Deacetylation of Triosephosphate Isomerase 1 Promotes Idiopathic Pulmonary Fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12529298/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARID1A Governs Genomic Stability and Proliferation in SCLC via c-MYC/PARP1 Suppression Driving Vulnerability to BET Inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12489181/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Artemis (DCLRE1C) Acts as a Target to Enhance Radiotherapy Response in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12564160/
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    SIK2 activates the autophagy‒apoptosis pathway through SP1 regulation to inhibit the progression of hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12528092/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Developing and optimizing a biocompatible tauopathy model using extracellular vesicle-mediated gene delivery
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    pmc.ncbi.nlm.nih.gov/articles/PMC12587183/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    New mechanistic insights into macrophage extracellular trap formation induced by a parasitic nematode, Strongyloides stercoralis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12592133/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C1orf50 Accelerates Epithelial-Mesenchymal Transition and the Cell Cycle of Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12577603/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role and mechanism of ubiquitin-specific protease 35 in ferroptosis of rheumatoid arthritis-fibroblast like synoviocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12549345/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UBXN7 facilitates SARS-CoV-2 replication via inhibiting the K48-linked ubiquitination of viral N protein
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    pmc.ncbi.nlm.nih.gov/articles/PMC12520364/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure and function of Full-length Tau
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    pmc.ncbi.nlm.nih.gov/articles/PMC12578172/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A distal enhancer of Pparα regulates thermogenesis and mitochondrial function in brown fat
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    The miR-34/449 clusters regulate the differentiation of ciliated cells in the oviduct via the Wnt/β-catenin signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12492746/
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    Stable production of immortalized hPC-MSC-derived extracellular vesicles: integrated cargo analysis and functional validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12590667/
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    FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12613929/
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    RUNX2 cooperates with SREBP1 to rewire cancer metabolism and promote aggressiveness
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    Modulation of transferrin receptor by HIV-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639691/
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    ARFGAP1 serves as a critical host factor during E30 infection: QS11 inhibits viral pathogenesis in hFcRn-IFNAR−/− mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12573814/
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    Multi-omics analysis reveals the crosstalk of epigenetic regulatory networks in cutaneous squamous cell carcinoma progression
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    USP13 promotes colorectal cancer progression by deubiquitinating and stabilizing HIF-1α
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639959/
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    Effect of heme oxygenase-1 on the expression of interferon-stimulated genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12512898/
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    Lung endothelial PEAR1 induces tumor cell dormancy
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    BRD9-p53-E2F1 circuit orchestrates cell growth and DNA damage repair in gastric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12492862/
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    A Notch signal pathway related gene signature predicts overall survival in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12506287/
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    Systematic Engineering of TROP2-Targeted CAR T-Cell Therapy Overcomes Resistance Pathways in Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580781/
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    P3H4 Enhances the Proliferation, Invasion, and Glycolysis of Hepatocellular Carcinoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12597767/
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    Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12542748/
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    EP300 compromises antitumor immunity by increasing SOCS1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12530425/
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    DKK3-LRP1 complex and a chemical inhibitor regulate Aβ clearance in models of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594171/
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    PLAMseq enables the proteo-genomic characterization of chromatin-associated proteins and protein interactions in a single workflow
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594174/
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    ASPL couples the assembly of stress granules with their VCP-mediated disassembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC12506973/
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    Resistance to radiation enhances metastasis by altering RNA metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533556/
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    Mechanochemical waves in focal adhesions during cell migration
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    Melatonin Overcomes Cancer Multidrug Resistance by Downregulating ABCB1 Expression and Modulating Mitochondrial Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586911/
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    3D-bioprinted liver cancer models derived from primary hepatocytes for simulating cancer initiation and drug screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12506986/
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    mRNA turnover dynamics are affected by cell differentiation and loss of the cytosine methyltransferase Nsun2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12529931/
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    Transcription factor 4 maintains endothelial cell identity by inhibiting endothelial to mesenchymal transition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12571441/
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    FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12524113/
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    Moesin controls cell–cell fusion and osteoclast function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12558046/
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    Porcine reproductive and respiratory syndrome virus activates the pentose phosphate pathway via the ROS/HIF-1α/G6PD axis to promote viral replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12599336/
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    Autoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
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    pmc.ncbi.nlm.nih.gov/articles/PMC12519202/
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    LeGO-3D: 3D imaging of lung metastases and vascularisation using light sheet fluorescence microscopy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12595114/
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    Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding
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    pmc.ncbi.nlm.nih.gov/articles/PMC12615796/
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    ABCC4 impairs the clearance of plasma LDL cholesterol through suppressing LDLR expression in the liver
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    pmc.ncbi.nlm.nih.gov/articles/PMC12491593/
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    DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens
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    pmc.ncbi.nlm.nih.gov/articles/PMC12589559/
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    Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603150/
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    Combined effects of restriction factors and transduction adjuvants on lentiviral vector gene transfer efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586428/
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    Villin like suppresses nasopharyngeal carcinoma proliferation by downregulating MYC
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    pmc.ncbi.nlm.nih.gov/articles/PMC12569157/
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    Immunocompetent C57BL/6 syngeneic mouse ovarian cancer models with defined genetic alterations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12504517/
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    Dipeptidase 1 is a functional receptor for a porcine coronavirus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12578638/
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    Epigenetic alterations facilitate transcriptional and translational programs in hypoxia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12611764/
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    Optical mapping of the interface between iPSC-derived grafts and swine myocardium suggests potential arrhythmia mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12583502/
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    Targeting GD2 with naxitamab overcomes GD3 synthase-driven immune suppression in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586714/
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    A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639036/
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    LUBAC modulates CBM complex functions downstream of TRAF6 in T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12602705/
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    A yeast surface display platform for characterizing CAR T cell responses to cancer antigens
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638309/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638947/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling and addressing on-target/off-tumor toxicity of claudin 18.2 targeted immunotherapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12579598/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638796/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12618888/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    qMaLioffG: a genetically encoded green fluorescence lifetime-based indicator enabling quantitative imaging of intracellular ATP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12615622/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12511557/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12494973/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The inner nuclear membrane protein LEMD3 organizes the 3D chromatin architecture to maintain vascular smooth muscle cell identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12495022/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell cycle regulator MYBL2 is a distinct vulnerability in acute myeloid leukemia
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    SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production
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    rs604702 confers breast cancer risk by influencing PCAT18/miR-759/SPRR3 axis
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    Small Extracellular Vesicles From Radioresistant H3K27M‐Pediatric Diffuse Midline Glioma Cells Modulate Tumor Phenotypes and Radiation Response
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    Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming
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    The Influence of Short Peptides on Cell Senescence and Neuronal Differentiation
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    Hemopexin Suppresses Hepatocellular Carcinoma via TNF-α-Mediated Mitochondrial Apoptosis
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    FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks
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    The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms
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    APP SUMOylation prevents BACE1 cleavage of APP and increases BACE1 degradation to promote the nonamyloidogenic pathway
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    Targeting dual-specificity phosphatase 23 to overcome chemoresistance and stem cell-like behavior in non-small cell lung cancer cells
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    Uncovering hidden protein modifications with native top-down mass spectrometry
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    Covariation MS uncovers a protein that controls cysteine catabolism
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    A UBH-UBX module amplifies p97/VCP’s unfolding power to facilitate protein extraction and degradation
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    Inhibition of ICAM1 diminishes stemness and enhances antitumor immunity in glioblastoma via β-catenin/PD-L1 signaling
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    Modular RNA interactions shape FXR1 condensates involved in mRNA localization and translation
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    ECD, a novel androgen receptor target promotes prostate cancer tumorigenesis by regulating glycolysis
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  168. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Screening of Medicines for Malaria Venture Open Boxes Identifies Potent SARS-CoV‑2 Papain-like Protease (PLpro) Inhibitors
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    Protocol for monitoring the stability of transcription factor EB using global protein stability assay
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  170. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
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  171. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Basement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis
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  172. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Requirements for establishment and epigenetic stability of mammalian heterochromatin
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    Robust calibration and quantification of FRET signals using multiplexed biosensor barcoding
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    ZNF469 promotes extracellular matrix production in normal and keloid dermal fibroblasts
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    Theranostic Potential of a New 64Cu-Labeled NOTA-R954 Peptide Conjugate for Kinin B1R Expressing Prostate Cancer
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    A Novel Serum-Free Triculture Model of Glioblastoma, Astrocytes, and Macrophages
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  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Model of Breast Cancer Micrometastasis in a Three-Dimensional (3D) Liver Spheroid for Testing an Antimetastatic Therapy
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    Molecular requirements for mammalian crinophagy highlight a key role for Ca2+-dependent Munc13-4
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    Poxvirus H5 mediates the formation of liquid-liquid phase separation condensates which promote virus factory assembly
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    Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out
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    The interplay between Wnt and mTOR signaling modulates ciliogenesis in human retinal epithelial cells
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    PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer
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    Enhancement of lentiviral vectors gene delivery against VEGFR2 expressing cells by co-display of the binding and fusogenic moieties: a two molecules targeting approach
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    BM-MSC-derived migrasomes reverse stroke-induced thymic atrophy and immunosuppression via Pin1 delivery to thymic epithelial cells
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    Trastuzumab Deruxtecan (T-DXd) Resistance via Loss of HER2 Expression and Binding
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    Genome editing or small molecule inhibition of KMT5A in CAR-T cells enhances antitumor immunity
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    Genome-wide mapping of EBV-induced genomic variations identifies the role of MUC19 in EBV latency
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    Peptide-MHC–targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells
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    Tau Axonal Sorting and Interaction With Synaptic Plasticity Modulators Is Domain‐ and Isoform‐Dependent in Human iPSC‐Derived Neurons
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    Local RhoA activation induces septin recruitment
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    Mapping of the hSOX10 protein interactome in human melanoma
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    EBNA1 SUMOylation by PIAS1 Suppresses EBV Lytic Replication and Enhances Episome Maintenance
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    Cysteine reactivity profiling identifies host regulators of Mycobacterium tuberculosis replication in human macrophages
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    Tissue Fluidity Mediates a Trade-off Between the Speed and Accuracy of Multicellular Patterning by Cell Sorting
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    Mammalian ZAP and KHNYN can independently restrict CpG-enriched avian viruses
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    Nanoscale restructuring of the immune synapse with an engager enhances NK cell function
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    Basal IFN-λ2/3 expression mediates tight junction formation in human epithelial cells
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    Analysis of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Interactome
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