3,889 Matching Annotations
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    Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905269/
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    Prevention of transgene silencing during human pluripotent stem cell differentiation
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    sciencedirect.com/science/article/pii/S1934590926000305
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    A 3D multi-compartment assembloid to study combined immune cell infiltration and cytotoxicity
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    sciencedirect.com/science/article/pii/S266723752600007X
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    ACSL4-associated lipid metabolism is a distinct therapeutic vulnerability in KMT2A-rearranged acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2211124726000884
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    NRF2 co-opts the SWI/SNF complex to drive liver cell plasticity
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    biorxiv.org/content/10.64898/2026.02.09.704724v1
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    Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000303
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    Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature
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    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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    HP1α depletion and TGFβ activation exert antagonistic effects on 3D genome organization
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    Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression
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    Bacterial vesicles from intratumoral L. salivarius enhance PD-1 blockade via FPR1-mediated macrophage polarization in gastric cancer
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    Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice
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    Glomerular basement membrane structural integrity dictates trans-tissue deposition of laminin in the kidney
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    The mTORC2 component SIN1 post-transcriptionally regulates TYMS levels and modulates P53 activity in response to 5-FU chemotherapy
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    Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition
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    Genome-wide screens identify core regulators of cell surface prion protein expression
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  18. Feb 2026
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    SpeckSeq enables high-throughput functional stratification of MEFV variants in autoinflammatory diseases
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    IGF2BP3/m6A-mediated intron retention isoform of DUSP6 promotes cisplatin resistance in nasopharyngeal carcinoma by inhibiting pyroptosis
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    An orthogonal CRISPR/Cpf1 platform for precise spatiotemporal gene regulation and osteoporotic fracture repair
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    Cellular Mg2+ decrease causes a distinctive NF-κB-dependent form of cell death
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    Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation
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    Dynamic estimation of metabolic state during CAR T cell production
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    Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis
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    HSPA1A and DNAJB1 regulate NELF condensate dynamics to safeguard transcriptional recovery under heat stress
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    T Cell Receptor Co-Stimulation Through Magnetogenetic Tools: A Platform for Wireless Rewiring of Cellular Signaling
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    Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability
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    The Lysine Demethylase KDM4C is an Oncogenic Driver and Regulates ERK Activity in KRAS Mutant Pancreatic Ductal Adenocarcinoma
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    Estrogen Production in Pancreatic Cancer Shapes a Tumor Suppressive Stromal Microenvironment
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    A neuron subtype-specific role of MEK-ERK signaling in axon survival via transcriptional regulation of Nmnat2
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    Pharmacological Targeting of NR4A1 Restrains Lipid Metabolism–Ferroptosis Axis in UVR-Induced Skin Aging
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    The castration-resistant prostate cancer-associated SNP rs11067228 facilitates neuroendocrine differentiation through an enhancer-mediated chromatin interaction with SRRM4
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    De novo MAP2K4 variants cause a novel neurodevelopmental syndrome with impaired JNK signaling in iPSC-derived neurons
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    Detecting the Activation of Endogenous Small GTPases via Fluorescent Signals Utilizing a Split mNeonGreen: Small GTPase ActIvitY ANalyzing (SAIYAN) System
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    SAMD9L inhibits flavivirus translation independently of its capacity to trigger innate immune response
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    The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition
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    Mapping cis- and trans-regulatory target genes of human-specific deletions
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    SNORA49 negatively regulates self-renewal of liver cancer stem cells and hepatocarcinogenesis via suppressing SOX9 transcription
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    Bromhexine inhibits SARS-CoV-2 Omicron and variant pseudovirus infection via ACE2-targeted mechanisms
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    ALYREF condensation stabilizes m5C-modified PARP10 mRNA and promotes PI3K-AKT signaling in ovarian cancer
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  60. Jan 2026
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    Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
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    CRISPR activation screens map the genomic landscape of cancer glycome remodeling
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    Scalable TCR synthesis and screening enable antigen reactivity mapping in vitiligo
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    Cholesterol-DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/admi.202500806
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    FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion
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    Generation of an iPSC-derived alveolar rhabdomyosarcoma cell line during directed endothelial differentiation
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    Pregnenolone promotes immune evasion through blocking endogenous retrovirus expression
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    Dual targeting of AMRC12 and Malassezia globosa disrupts MYC liquid condensates-driven nuclear pore complex biogenesis in neuroblastoma
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    Genome-wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer
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    MRTF-dependent cytoskeletal dynamics drive efficient cell cycle progression
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    Ribosome-binding protein 1 maintains peroxisome biogenesis
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    NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress
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    Autocrine TGFβ2 enforces a transcriptionally hybrid cell state in Ewing sarcoma
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    EMT activates ER-to-Golgi trafficking through upregulation of REEP2 to promote lung cancer progression
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    Anti-CRISPR-mediated continuous directed evolution of CRISPR-Cas9 in human cells
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    A Novel Diagnostic Tool for West Nile Virus Lineage 1a and 2 Using a CRISPR-Cas12a System
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    Discovering the complete enhancer map of human herpesviruses using a natural language processing model
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    Armored macrophage-targeted CAR-T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth
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    sciencedirect.com/science/article/pii/S1535610825005550
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    The hemopexin domain of matrix metalloproteinase-9 attenuates lipopolysaccharide-induced interleukin-6 secretion in liver
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    Myomaker and ether lipids cooperate to promote fusion-competent membrane states
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    IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma
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    Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication
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    Context-specific Angiogenin-mediated tRNA fragments (tDRs) biogenesis shapes the mitochondrial stress response.
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  174. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UBXN7 facilitates SARS-CoV-2 replication via inhibiting the K48-linked ubiquitination of viral N protein
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    pmc.ncbi.nlm.nih.gov/articles/PMC12520364/
  175. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure and function of Full-length Tau
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    pmc.ncbi.nlm.nih.gov/articles/PMC12578172/
  176. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A distal enhancer of Pparα regulates thermogenesis and mitochondrial function in brown fat
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    pmc.ncbi.nlm.nih.gov/articles/PMC12574865/
  177. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The miR-34/449 clusters regulate the differentiation of ciliated cells in the oviduct via the Wnt/β-catenin signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12492746/
  178. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stable production of immortalized hPC-MSC-derived extracellular vesicles: integrated cargo analysis and functional validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12590667/
  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12613929/
  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RUNX2 cooperates with SREBP1 to rewire cancer metabolism and promote aggressiveness
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    pmc.ncbi.nlm.nih.gov/articles/PMC12577400/
  181. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of transferrin receptor by HIV-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639691/
  182. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARFGAP1 serves as a critical host factor during E30 infection: QS11 inhibits viral pathogenesis in hFcRn-IFNAR−/− mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12573814/
  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multi-omics analysis reveals the crosstalk of epigenetic regulatory networks in cutaneous squamous cell carcinoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12613370/
  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP13 promotes colorectal cancer progression by deubiquitinating and stabilizing HIF-1α
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639959/
  185. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effect of heme oxygenase-1 on the expression of interferon-stimulated genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12512898/
  186. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lung endothelial PEAR1 induces tumor cell dormancy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12581312/
  187. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRD9-p53-E2F1 circuit orchestrates cell growth and DNA damage repair in gastric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12492862/
  188. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Notch signal pathway related gene signature predicts overall survival in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12506287/
  189. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic Engineering of TROP2-Targeted CAR T-Cell Therapy Overcomes Resistance Pathways in Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580781/
  190. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P3H4 Enhances the Proliferation, Invasion, and Glycolysis of Hepatocellular Carcinoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12597767/
  191. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12542748/
  192. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EP300 compromises antitumor immunity by increasing SOCS1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12530425/
  193. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DKK3-LRP1 complex and a chemical inhibitor regulate Aβ clearance in models of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594171/
  194. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLAMseq enables the proteo-genomic characterization of chromatin-associated proteins and protein interactions in a single workflow
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594174/
  195. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ASPL couples the assembly of stress granules with their VCP-mediated disassembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC12506973/
  196. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resistance to radiation enhances metastasis by altering RNA metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533556/
  197. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanochemical waves in focal adhesions during cell migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12494029/
  198. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Melatonin Overcomes Cancer Multidrug Resistance by Downregulating ABCB1 Expression and Modulating Mitochondrial Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586911/
  199. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    3D-bioprinted liver cancer models derived from primary hepatocytes for simulating cancer initiation and drug screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12506986/
  200. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mRNA turnover dynamics are affected by cell differentiation and loss of the cytosine methyltransferase Nsun2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12529931/
  201. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcription factor 4 maintains endothelial cell identity by inhibiting endothelial to mesenchymal transition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12571441/
  202. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12524113/