3,113 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expression of DNAJB1-PRKACA oncogene suppresses the differentiation potential of liver progenitor organoids towards a hepatocyte lineage
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    1. scibot 19 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1038/s41598-025-11028-4

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    pmc.ncbi.nlm.nih.gov/articles/PMC12267505/
  3. www.sciencedirect.com www.sciencedirect.com
    Drug delivery agent that acts as a drug for synergistic activity
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    1. scibot 19 Jul 2025
      plasmid_12259

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    sciencedirect.com/science/article/pii/S2589004225011514
  4. www.sciencedirect.com www.sciencedirect.com
    TAF1 is required for fetal but not adult hematopoiesis in mice
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    1. scibot 17 Jul 2025
      Jackson LaboratoryStrain#: 003556

      DOI: 10.1016/j.devcel.2025.06.027

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    2. scibot 17 Jul 2025
      AddgenePlasmid #12259

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    sciencedirect.com/science/article/pii/S1534580725004058
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
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    1. scibot 17 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1158/0008-5472.CAN-24-3844

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    pmc.ncbi.nlm.nih.gov/articles/PMC12260515/
  6. 52.53.155.43 52.53.155.43
    T-cadherin is a novel regulator of pericyte function during angiogenesis
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    1. scibot 16 Jul 2025
      #12259

      DOI: 10.1152/ajpcell.00326.2022

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    52.53.155.43/4f40ed50d759c2cc0818ba0d29452b01c721b3b6/dasen-et-al-2023-t-cadherin-is-a-novel-regulator-of-pericyte-function-during-angiogenesis-html.html
  7. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225013732-main-html.html
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    1. scibot 16 Jul 2025
      Addgene  12259

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    52.53.155.43/73ec1f388f41da4ad69bbc809bebcfccf70e9065/1-s2.0-S2589004225013732-main-html.html
  8. elifesciences.org elifesciences.org
    PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation
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    1. scibot 16 Jul 2025
      RRID:Addgene_12259

      DOI: 10.7554/eLife.107556.1

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    elifesciences.org/reviewed-preprints/107556
  9. www.sciencedirect.com www.sciencedirect.com
    A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy
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    1. scibot 16 Jul 2025
      Addgene_12259

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    sciencedirect.com/science/article/pii/S2667237525001420
  10. www.sciencedirect.com www.sciencedirect.com
    An alternate receptor for adeno-associated viruses
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    1. scibot 15 Jul 2025
      Addgene# 12259

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    sciencedirect.com/science/article/pii/S0092867425006920
  11. www.sciencedirect.com www.sciencedirect.com
    Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity
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    1. scibot 15 Jul 2025
      AddgenePlasmid# 12259

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    sciencedirect.com/science/article/pii/S0092867425006385
  12. www.biorxiv.org www.biorxiv.org
    Engineering a human-based translational activator for targeted protein expression restoration
    1
    1. scibot 15 Jul 2025
      Addgene_12259

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    biorxiv.org/content/10.1101/2025.07.09.663984v1
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PINK1 Loss of Function Selectively Alters the Mitochondrial‐Derived Vesicle Pathway
    1
    1. scibot 15 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1096/fba.2024-00200

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    pmc.ncbi.nlm.nih.gov/articles/PMC12242855/
  14. www.sciencedirect.com www.sciencedirect.com
    The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint
    1
    1. scibot 15 Jul 2025
      plasmid_12259

      DOI: 10.1016/j.celrep.2025.115966

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    sciencedirect.com/science/article/pii/S2211124725007375
  15. www.sciencedirect.com www.sciencedirect.com
    Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4
    1
    1. scibot 15 Jul 2025
      Plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124725007326
  16. www.sciencedirect.com www.sciencedirect.com
    Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of intestinal stemness
    1
    1. scibot 15 Jul 2025
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S221112472500720X
  17. www.cell.com www.cell.com
    A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma
    1
    1. scibot 15 Jul 2025
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    cell.com/cell/abstract/S0092-8674(25)00685-3
  18. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
    1
    1. scibot 15 Jul 2025
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1535610825002612
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SPOP-dependent destabilization of SYT12 in a GSK-3β-dependent manner in papillary thyroid cancer cells
    1
    1. scibot 13 Jul 2025
      pMD2.G

      DOI: 10.1007/s10238-025-01791-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC12245953/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Regulates a DNA Repair Gene Expression Program in Small Cell Carcinoma of the Ovary, Hypercalcemic Type
    1
    1. scibot 13 Jul 2025
      RRID:Addgene_12259

      DOI: 10.3390/cancers17132255

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    pmc.ncbi.nlm.nih.gov/articles/PMC12248706/
  21. Jul 2025
  22. www.biorxiv.org www.biorxiv.org
    Active Merlin Binds RalB to Regulate Exocytosis
    1
    1. scibot 12 Jul 2025
      #12259

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    biorxiv.org/content/10.1101/2025.06.13.659557v1
  23. www.nature.com www.nature.com
    The GATE glycoprotein complex enhances human cytomegalovirus entry in endothelial cells
    1
    1. scibot 11 Jul 2025
      Addgene plasmid no. 12259

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    nature.com/articles/s41564-025-02025-4
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alternate MHC I antigen presentation pathways allow CD8+ T-cell recognition and killing of cancer cells in the absence of ß2M or TAP
    1
    1. scibot 10 Jul 2025
      plasmid_12259

      DOI: 10.1158/2326-6066.CIR-24-0320

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    pmc.ncbi.nlm.nih.gov/articles/PMC11717633/
  25. www.biorxiv.org www.biorxiv.org
    Anthrax toxin receptor 2 is the Receptor for Clostridium perfringens NetF: Structural Insights into Toxin Binding and Pore Formation
    1
    1. scibot 10 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1101/2025.07.02.662835

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    biorxiv.org/content/10.1101/2025.07.02.662835v1
  26. www.biorxiv.org www.biorxiv.org
    KAT6A/B inhibition synergizes with retinoic acid and enhances the efficacy of GD2-targeted immunotherapy in neuroblastoma
    1
    1. scibot 10 Jul 2025
      RRID:Addgene_12259

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    biorxiv.org/content/10.1101/2025.07.01.662644v1
  27. www.biorxiv.org www.biorxiv.org
    A lentiviral fluorescent reporter to study circadian rhythms in single cells
    1
    1. scibot 10 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1101/2025.06.30.661926

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    biorxiv.org/content/10.1101/2025.06.30.661926v1
  28. www.science.org www.science.org
    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
    1
    1. scibot 08 Jul 2025
      no. 12259

      DOI: 10.1126/sciadv.adu2339

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    science.org/doi/10.1126/sciadv.adu2339
  29. academic.oup.com academic.oup.com
    Toward optimizing diversifying base editors for high-throughput mutational scanning studies
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    1. scibot 08 Jul 2025
      Addgene, #12259

      DOI: 10.1093/nar/gkaf620

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    academic.oup.com/nar/article/53/12/gkaf620/8185969
  30. elifesciences.org elifesciences.org
    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence
    1
    1. scibot 08 Jul 2025
      RRID:Addgene_12259

      DOI: 10.7554/eLife.101984

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    elifesciences.org/articles/101984
  31. 52.53.155.43 52.53.155.43
    1-s2.0-S0016508525057324-main-html.html
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    1. scibot 08 Jul 2025
      RRID:Addgene_12259

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    52.53.155.43/a363e4ae90be5a0c17cae72bbc9ca19379f34011/1-s2.0-S0016508525057324-main-html.html
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties
    1
    1. scibot 04 Jul 2025
      Addgene_12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12214878/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
    1
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      Addgene_12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12209774/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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      RRID:Addgene_12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  35. www.sciencedirect.com www.sciencedirect.com
    Chromosomal tethering and mitotic transcription promote ecDNA nuclear inheritance
    1
    1. scibot 03 Jul 2025
      Addgene #12259

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    sciencedirect.com/science/article/pii/S1097276525005428
  36. www.sciencedirect.com www.sciencedirect.com
    MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction
    1
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      RRID: Addgene_12259

      DOI: 10.1016/j.molcel.2025.06.005

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    sciencedirect.com/science/article/pii/S1097276525005052
  37. www.sciencedirect.com www.sciencedirect.com
    TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling
    1
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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S109727652500509X
  38. cancerci.biomedcentral.com cancerci.biomedcentral.com
    The GD3 ganglioside promotes cell growth, plasticity and chemotherapy resistance of human glioblastoma cancer stem cells
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      Addgene #12259

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    cancerci.biomedcentral.com/articles/10.1186/s12935-025-03790-2
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Blood group O expression in normal tissues and tumors
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    1. scibot 03 Jul 2025
      plasmid #12259

      DOI: 10.1111/febs.70172

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70172
  40. www.nature.com www.nature.com
    Molecular docking and biological evaluation of a novel IWS1 inhibitor for the treatment of human retroperitoneal liposarcoma
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    1. scibot 03 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1038/s41598-025-07215-y

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    nature.com/articles/s41598-025-07215-y
  41. www.sciencedirect.com www.sciencedirect.com
    Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer
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    1. scibot 02 Jul 2025
      Addgene #12259

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    sciencedirect.com/science/article/pii/S2666379125002848
  42. journals.plos.org journals.plos.org
    IRF6 controls Epstein-Barr virus (EBV) lytic reactivation and differentiation in EBV-infected epithelial cells
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    1. scibot 01 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1371/journal.ppat.1013236

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    journals.plos.org/plospathogens/article
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leveraging femtosecond laser machining for the fabrication of tubular-based Organ-on-Chip systems: modeling cancer metastasis from invasion to intravasation
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    1. scibot 01 Jul 2025
      RRID:Addgene_12259

      DOI: 10.1016/j.mtbio.2025.101926

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    pmc.ncbi.nlm.nih.gov/articles/PMC12205662/
  44. Jun 2025
  45. www.nature.com www.nature.com
    Nerve-to-cancer transfer of mitochondria during cancer metastasis
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    A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer
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    Functional assessment of all ATM SNVs using prime editing and deep learning
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation
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    Systematic profiling reveals betaine as an exercise mimetic for geroprotection
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    ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation
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    High-content image-based pooled screens reveal regulators of synaptogenesis
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    De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation
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  55. www.nature.com www.nature.com
    PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer
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    Protocol for establishing genetically engineered murine lung organoids mimicking cell plasticity and regeneration
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    Deletion of Ascl1 in pancreatic β-cells improves insulin secretion, promotes parasympathetic innervation, and attenuates dedifferentiation during metabolic stress
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  58. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Unsupervised Machine Learning-Based Process Analytical Tools for Near Real-Time Cell Morphology Analysis During CAR-T Cell Manufacturing
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  59. www.cell.com www.cell.com
    Combination of in vivo and in vitro phosphoproteomics determines the PP2A target repertoire on proteome scale
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    Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation
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  61. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer
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  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
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    Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing
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  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DEPP1: A prognostic biomarker linked to stroma-rich and immunosuppressive microenvironment, promoting oxaliplatin resistance in gastric cancer
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    Targeting the Exonic Circular OGT RNA/O-GlcNAc Transferase/Forkhead Box C1 Axis Inhibits Asparagine- and Alanine-Mediated Ferroptosis Repression in Neuroblastoma Progression
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  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome Destabilization
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    Phosphoproteomics Reveals L1CAM-Associated Signaling Networks in High-Grade Serous Ovarian Carcinoma: Implications for Radioresistance and Tumorigenesis
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    Metabolic profiling of glioblastoma and identification of G0S2 as a metabolic target
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    Pan-cancer analysis of TMED2: unraveling potential immune characteristics and prognostic value in cancer therapy
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  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Resolved Panoramic in vivo CRISPR Screen via Perturb-DBiT
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    STAT3, MYC, and EBNA1 cooperate through a ZC3H18 transcriptional network to regulate survival and proliferation of EBV-positive lymphomas
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  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    绒毛样蛋白VILL通过与LMO7蛋白相互作用抑制鼻咽癌细胞的增殖
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    An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors
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    CDK2 inhibition produces a persistent population of polyploid cancer cells
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  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human cytomegalovirus gH/gL/gO binding to PDGFRα provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies
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  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ELF3-TRIM22-MAVS signaling axis regulates type I interferon and antiviral responses
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  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Syntaxin-6 restricts SARS-CoV-2 infection by facilitating virus trafficking to autophagosomes
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  81. www.science.org www.science.org
    In vivo CRISPR activation screen identifies acyl-CoA–binding protein as a driver of bone metastasis
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  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Armored human CAR Treg cells with PD1 promoter-driven IL-10 have enhanced suppressive function
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      DOI: 10.1126/sciadv.adx7845

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  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gradual labeling with fluorogenic probes: A general method for MINFLUX imaging and tracking
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  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FTO regulates ELK3-mediated metabolic rewiring and represents a unique therapeutic target in T cell leukemia
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  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Orthogonal resistance mechanisms of classical- and induced-proximity inhibitors
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathways
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  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair
    1
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      12259

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  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle
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      12,259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12087647/
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interferon-induced PARP14-mediated ADP-ribosylation in p62 bodies requires the ubiquitin-proteasome system
    1
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      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12084362/
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thermostable lamprey variable lymphocyte receptor antibody for detection of Plasmodium falciparum histidine rich protein-2
    1
    1. scibot 15 Jun 2025
      pMD2G

      DOI: 10.1038/s41598-025-97790-x

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    pmc.ncbi.nlm.nih.gov/articles/PMC12085579/
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Luteolin targets MKK4 to attenuate particulate matter-induced MMP-1 and inflammation in human keratinocytes
    1
    1. scibot 15 Jun 2025
      pMD2.0G

      DOI: 10.1038/s41598-025-01090-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC12081746/
  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex
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      12259

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  93. www.nature.com www.nature.com
    EndoMAP.v1 charts the structural landscape of human early endosome complexes
    1
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      Addgene, 12259

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    nature.com/articles/s41586-025-09059-y
  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screen decodes SWI/SNF chromatin remodeling complex assembly
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    1. scibot 15 Jun 2025
      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12125367/
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficient generation of germline chimeras in a non-rodent species using rabbit induced pluripotent stem cells
    1
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      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12134177/
  96. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia
    1
    1. scibot 15 Jun 2025
      pM2.G

      DOI: 10.1038/s41467-025-60304-4

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    pmc.ncbi.nlm.nih.gov/articles/PMC12130354/
  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS
    1
    1. scibot 15 Jun 2025
      pMD2.G

      DOI: 10.1038/s41467-025-60297-0

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  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of tumor-intrinsic NAT10 enhances antitumor immunity by triggering type I interferon response via MYC/CDK2/DNMT1 pathway
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      12259

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  99. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly
    1
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  100. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction
    1
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      12259

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  101. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXA2 promotes metastatic competence in small cell lung cancer
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      12259

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  102. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens
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      12259

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  103. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12
    1
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      12259

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  104. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes
    1
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      12259

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  105. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA-binding proteins DND1 and NANOS3 cooperatively suppress the entry of germ cell lineage
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      12259

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  106. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer
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      12259

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  107. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for in vivo CRISPR knockout screening of autophagy genes to identify breast cancer metastasis suppressors
    1
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      12259

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  108. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Newcastle disease virus induces degradation of folliculin to regulate host cell energy metabolism and facilitate viral replication
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      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12164175/
  109. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fighting RNA viruses with a gold nanoparticle Cas13d gene-editing armor
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      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12088821/
  110. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gallium disrupts endoplasmic reticulum iron metabolism to induce lipid metabolic reprogramming in glioblastoma cells
    1
    1. scibot 15 Jun 2025
      VSV-G

      DOI: 10.1016/j.isci.2025.112404

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  111. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation as a target in PIK3CA-mutated head and neck cancer
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      12259

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  112. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rational Design and Organoid‐Based Evaluation of a Cocktail CAR‐γδ T Cell Therapy for Heterogeneous Glioblastoma
    1
    1. scibot 15 Jun 2025
      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12097020/
  113. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NKX2‐5/LHX1 and UHRF1 Establishing a Positive Feedback Regulatory Circuitry Drives Esophageal Squamous Cell Carcinoma through Epigenetic Dysregulation
    1
    1. scibot 15 Jun 2025
      12259

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  114. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
    1
    1. scibot 15 Jun 2025
      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12097018/
  115. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates
    1
    1. scibot 15 Jun 2025
      plasmid_12259

      DOI: 10.7554/eLife.102301

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    pmc.ncbi.nlm.nih.gov/articles/PMC12119088/
  116. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Creation of Genetically Modified Adipocytes for Tissue Engineering: Creatine Kinase B Overexpression Leads to Stimulated Glucose Uptake and Mitochondrial Potential Growth, but Lowered Lipid Synthesis
    1
    1. scibot 15 Jun 2025
      Plasmid_12259

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  117. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD44 Marks Dormant Tumor Cells After HER2 Inhibition in Breast Cancer Cells
    1
    1. scibot 15 Jun 2025
      Addgene_12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12112730/
  118. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Xenoline-polarized macrophages as a physiologically relevant in vitro model of tumor-associated macrophages in glioblastoma
    1
    1. scibot 15 Jun 2025
      Plasmid_12259

      DOI: 10.21203/rs.3.rs-6567445/v1

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  119. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pancreatic cancer-restricted cryptic antigens are targets for T cell recognition
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    1. scibot 15 Jun 2025
      RRID:Addgene_12259

      DOI: 10.1126/science.adk3487

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  120. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma
    1
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      Addgene_12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12120064/
  121. 52.53.155.43 52.53.155.43
    Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell function
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      Addgene_12259

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    52.53.155.43/bb3fc3d48d1d1a3ea4bd88205a0b31e5070fc2a9/PDF-html.html
  122. link.springer.com link.springer.com
    Differentiation of Brain Mural Cells from Human Pluripotent Stem Cell-Derived Neural Crest by Activation of Notch3 Signaling
    1
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      Addgene_12259

      DOI: 10.1007/978-1-0716-4474-4_2

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    link.springer.com/protocol/10.1007/978-1-0716-4474-4_2
  123. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disruption of ATR Signaling by Epstein–Barr Virus Latent Membrane Protein 1 Sensitizes Nasopharyngeal Carcinoma Cells to Cisplatin
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  124. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction
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  125. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Live Cell Imaging‐Compatible Bioreactor for the Interrogation of Cellular Responses to Modulated Flow Conditions
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      plasmid_12259

      DOI: 10.1002/advs.202417141

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  126. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions
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      plasmid_12259

      DOI: 10.1002/advs.202412953

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    pmc.ncbi.nlm.nih.gov/articles/PMC12120733/
  127. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function
    1
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      addgene_12259

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  128. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation
    1
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      Addgene_12

      DOI: 10.1186/s13059-025-03640-4

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    pmc.ncbi.nlm.nih.gov/articles/PMC12164210/
  129. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation
    1
    1. scibot 15 Jun 2025
      plasmid_12

      DOI: 10.1002/advs.202404938

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    pmc.ncbi.nlm.nih.gov/articles/PMC12120771/
  130. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lovastatin Targets the USP14–Survivin Axis to Suppress Triple-Negative Breast Cancer via Ubiquitin-Mediated Proteasomal Degradation
    1
    1. scibot 14 Jun 2025
      pMD2.G,

      DOI: 10.3390/cells14110816

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    pmc.ncbi.nlm.nih.gov/articles/PMC12154129/
  131. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation-induced SUMOylation promotes Ulk4 condensation at the ciliary tip to transduce Hedgehog signal
    1
    1. scibot 14 Jun 2025
      plasmid #12259

      DOI: 10.1242/jcs.263695

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    pmc.ncbi.nlm.nih.gov/articles/PMC12148026/
  132. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PELI2 inhibits colorectal cancer development through MAPK signaling pathway
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1186/s10020-025-01294-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC12160117/
  133. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1128/mbio.00832-25

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    pmc.ncbi.nlm.nih.gov/articles/PMC12153310/
  134. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FEBS Press
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    1. scibot 14 Jun 2025
      12259

      DOI: 10.1111/febs.70040

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    pmc.ncbi.nlm.nih.gov/articles/PMC12138165/
  135. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity
    1
    1. scibot 14 Jun 2025
      12,259

      DOI: 10.1080/15548627.2024.2367183

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    pmc.ncbi.nlm.nih.gov/articles/PMC11572255/
  136. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of potential small molecule inhibitors against β-hCG: an in silico study with in vitro validation
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1039/d4ra08663e

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    pmc.ncbi.nlm.nih.gov/articles/PMC12150210/
  137. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1038/s41593-025-01952-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC12148940/
  138. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1038/s41586-025-08980-6

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    pmc.ncbi.nlm.nih.gov/articles/PMC12158785/
  139. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1038/s41467-025-60583-x

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    pmc.ncbi.nlm.nih.gov/articles/PMC12141619/
  140. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SWI/SNF ATPase silenced HLF potentiates lung metastasis in solid cancers
    1
    1. scibot 14 Jun 2025
      12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12141477/
  141. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer
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    1. scibot 14 Jun 2025
      Addgene12259

      DOI: 10.1016/j.xcrm.2025.102192

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    sciencedirect.com/science/article/pii/S2666379125002654
  142. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Co-targeting BMI1 and MYC to eliminate cancer stem cells in squamous cell carcinoma
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1016/j.xcrm.2025.102077

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    pmc.ncbi.nlm.nih.gov/articles/PMC12147845/
  143. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GLI2-HRD1 axis facilitates 5-FU resistance in gastric cancer cells by regulating ubiquitination degradation of UCK2
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1016/j.tranon.2025.102423

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    pmc.ncbi.nlm.nih.gov/articles/PMC12159939/
  144. www.sciencedirect.com www.sciencedirect.com
    CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance
    1
    1. scibot 14 Jun 2025
      AddgeneCat# 12259

      DOI: 10.1016/j.molcel.2025.04.006

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    sciencedirect.com/science/article/pii/S1097276525003090
  145. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic ChREBP reciprocally modulates systemic insulin sensitivity in NAFLD
    1
    1. scibot 14 Jun 2025
      12259

      DOI: 10.1016/j.jbc.2025.108556

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    pmc.ncbi.nlm.nih.gov/articles/PMC12155594/
  146. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation
    1
    1. scibot 14 Jun 2025
      pMD2G

      DOI: 10.1016/j.jbc.2025.108551

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    pmc.ncbi.nlm.nih.gov/articles/PMC12151214/
  147. www.sciencedirect.com www.sciencedirect.com
    SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases
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    1. scibot 14 Jun 2025
      12259

      DOI: 10.1016/j.celrep.2025.115588

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    sciencedirect.com/science/article/pii/S2211124725003596
  148. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusogenic Nanoreactor‐Based Detection of Extracellular Vesicle‐derived miRNAs for Diagnosing Atherosclerosis
    1
    1. scibot 14 Jun 2025
      12 259

      DOI: 10.1002/smll.202501789

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    pmc.ncbi.nlm.nih.gov/articles/PMC12160682/
  149. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance
    1
    1. scibot 14 Jun 2025
      plasmid_12259

      DOI: 10.1371/journal.pgen.1011677

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    pmc.ncbi.nlm.nih.gov/articles/PMC12148233/
  150. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Control of epithelial tissue organization by mRNA localization
    1
    1. scibot 14 Jun 2025
      plasmid_12259

      DOI: 10.1038/s41467-025-60532-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC12141530/
  151. www.sciencedirect.com www.sciencedirect.com
    Protocol for genetic dissection of class switch recombination using genome-editing tools
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    1. scibot 13 Jun 2025
      Addgene #12259

      DOI: 10.1016/j.xpro.2025.103882

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    sciencedirect.com/science/article/pii/S2666166725002886
  152. www.sciencedirect.com www.sciencedirect.com
    Vault RNAs aid RNA virus infection by facilitating cytoplasmic localization of hnRNP C and ELAVL1
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    1. scibot 13 Jun 2025
      Addgene#12259

      DOI: 10.1016/j.celrep.2025.115823

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    sciencedirect.com/science/article/pii/S2211124725005947
  153. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer
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    1. scibot 13 Jun 2025
      RRID:Addgene_12259

      DOI: 10.3390/ijms26115200

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    pmc.ncbi.nlm.nih.gov/articles/PMC12154493/
  154. www.sciencedirect.com www.sciencedirect.com
    The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
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    1. scibot 13 Jun 2025
      RRID:Addgene_12259

      DOI: 10.1016/j.cmet.2025.05.010

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    sciencedirect.com/science/article/pii/S1550413125002669
  155. www.sciencedirect.com www.sciencedirect.com
    The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance
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    1. scibot 12 Jun 2025
      AddgeneCat# 12259

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    sciencedirect.com/science/article/pii/S109727652500454X
  156. www.sciencedirect.com www.sciencedirect.com
    Regulation of Rho guanine nucleotide exchange factor 3 by phosphorylation in the PH domain
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    1. scibot 12 Jun 2025
      AddgenePlasmid #12259

      DOI: 10.1016/j.isci.2025.112753

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    sciencedirect.com/science/article/pii/S2589004225010144
  157. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screening Highlights PFKFB3 Gene as a Major Contributor to 5-Fluorouracil Resistance in Esophageal Cancer
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    1. scibot 12 Jun 2025
      RRID:Addgene_12259

      DOI: 10.3390/cancers17101637

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    pmc.ncbi.nlm.nih.gov/articles/PMC12109790/
  158. www.sciencedirect.com www.sciencedirect.com
    Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells
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      Addgene#12259

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    sciencedirect.com/science/article/pii/S1097276525004587
  159. www.sciencedirect.com www.sciencedirect.com
    Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
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      Plasmid #12259

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    sciencedirect.com/science/article/pii/S1074761325002328
  160. www.sciencedirect.com www.sciencedirect.com
    RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors
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    1. scibot 11 Jun 2025
      Addgene12259

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    sciencedirect.com/science/article/pii/S221112472500573X
  161. 52.53.155.43 52.53.155.43
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      RRID:  Addgene_12259

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    52.53.155.43/e9fe0912dd31f8e7ff03b2811eb8d2b4310b34d6/PDF-html.html
  162. www.cell.com www.cell.com
    Pro-ferroptotic lipids as key control points for caveola formation and disassembly
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    1. scibot 11 Jun 2025
      Addgene ID# 12259

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    cell.com/cell-reports/fulltext/S2211-1247(25)00560-1
  163. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
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  164. www.sciencedirect.com www.sciencedirect.com
    Synaptic activity causes minute-scale changes in BAF complex composition and function
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      RRID:Addgene_12259

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  165. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225011162-main-html.html
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      RRID:Addgene_12259

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  166. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones
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      RRID:Addgene_12259

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    pmc.ncbi.nlm.nih.gov/articles/PMC12117018/
  167. www.sciencedirect.com www.sciencedirect.com
    Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer
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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2666379125002332
  168. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225010776-main-html.html
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      RRID:Addgene_12259

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  169. www.sciencedirect.com www.sciencedirect.com
    Targeting IDH2 promotes antitumor immunity through epigenetic activation of cGAS-STING pathway
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      RRID: Addgene_12259

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    sciencedirect.com/science/article/pii/S0169500225005033
  170. May 2025
  171. www.sciencedirect.com www.sciencedirect.com
    Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity
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      Addgene_12259

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    IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner
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    Direct Arp2/3-vinculin binding is required for pseudopod extension, but only on compliant substrates and in 3D
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  177. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway
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  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    Division of labor among H3K4 methyltransferases defines distinct facets of homeostatic plasticity
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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates
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    Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus
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    Inherited deficiency of DIAPH1 identifies a DNA double strand break repair pathway regulated by γ-actin
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    Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface
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