2,392 Matching Annotations
  1. Mar 2022
  2. elifesciences.org elifesciences.org
    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking
    1
    1. scibot 31 Mar 2022
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      DOI: 10.7554/eLife.69229

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    elifesciences.org/articles/69229
  3. academic.oup.com academic.oup.com
    Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
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    1. scibot 31 Mar 2022
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      DOI: 10.1093/nar/gkac178

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac178/6553119
  4. www.sciencedirect.com www.sciencedirect.com
    Genome-wide analysis of haploinsufficiency in human embryonic stem cells
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    1. scibot 30 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722003175
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    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
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    1. scibot 30 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722003035
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    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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    1. scibot 27 Mar 2022
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    sciencedirect.com/science/article/pii/S1097276522002192
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    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
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    1. scibot 27 Mar 2022
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    sciencedirect.com/science/article/pii/S1074761322001248
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    A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis
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    1. scibot 27 Mar 2022
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    sciencedirect.com/science/article/pii/S2451945622000940
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    A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
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    1. scibot 26 Mar 2022
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    sciencedirect.com/science/article/pii/S2405471222000849
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
    1
    1. scibot 26 Mar 2022
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      DOI: 10.3390/cancers14061375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8945883/
  11. 52.53.155.43 52.53.155.43
    Optochemical Control of mTOR Signaling and mTOR-Dependent Autophagy
    1
    1. scibot 24 Mar 2022
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      DOI: 10.1021/acsptsci.1c00230

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    52.53.155.43/5f0a00228a932c0536b21b4ce3c5456b55ea2744/acsptsci.1c00230-html.html
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    The mTOR chromatin-bound interactome in prostate cancer
    1
    1. scibot 23 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002753
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants
    1
    1. scibot 23 Mar 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC8898742/
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    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
    1
    1. scibot 18 Mar 2022
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    sciencedirect.com/science/article/pii/S1550413122000535
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    CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome
    1
    1. scibot 18 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002741
  16. www.embopress.org www.embopress.org
    CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia
    1
    1. scibot 18 Mar 2022
      RRID:Addgene_12260

      DOI: 10.15252/emmm.202114990

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    embopress.org/doi/abs/10.15252/emmm.202114990
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    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
    1
    1. scibot 18 Mar 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.taap.2022.115973

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    sciencedirect.com/science/article/pii/S0041008X22001181
  18. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
    1
    1. scibot 16 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002583
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    Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
    1
    1. scibot 16 Mar 2022
      plasmid_12260

      DOI: 10.1016/j.neuron.2022.02.017

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    sciencedirect.com/science/article/pii/S0896627322001842
  20. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
    1
    1. scibot 11 Mar 2022
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      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
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    Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms
    1
    1. scibot 09 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002091
  22. www.sciencedirect.com www.sciencedirect.com
    Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors
    1
    1. scibot 09 Mar 2022
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    sciencedirect.com/science/article/pii/S0092867422001428
  23. www.sciencedirect.com www.sciencedirect.com
    Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
    1
    1. scibot 09 Mar 2022
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    sciencedirect.com/science/article/pii/S107476132200084X
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses
    1
    1. scibot 09 Mar 2022
      RRID:Addgene_12260

      DOI: 10.3389/fphys.2022.769325

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    ncbi.nlm.nih.gov/pmc/articles/PMC8895044/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells
    1
    1. scibot 09 Mar 2022
      RRID:Addgene_12260

      DOI: 10.1093/narcan/zcac007

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    ncbi.nlm.nih.gov/pmc/articles/PMC8892060/
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    Local hyperthermia therapy induces browning of white fat and treats obesity
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    1. scibot 06 Mar 2022
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    sciencedirect.com/science/article/pii/S0092867422001441
  27. www.nature.com www.nature.com
    Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors
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    1. scibot 05 Mar 2022
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      DOI: 10.1038/s41377-022-00729-4

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    nature.com/articles/s41377-022-00729-4
  28. www.nature.com www.nature.com
    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
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    1. scibot 05 Mar 2022
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      DOI: 10.1038/s41596-021-00669-0

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    nature.com/articles/s41596-021-00669-0
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
    1
    1. scibot 04 Mar 2022
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      DOI: 10.1158/2159-8290.CD-20-1066

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    ncbi.nlm.nih.gov/pmc/articles/PMC8418998/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells
    1
    1. scibot 04 Mar 2022
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      DOI: 10.3390/pharmaceutics14020329

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    ncbi.nlm.nih.gov/pmc/articles/PMC8880011/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
    1
    1. scibot 04 Mar 2022
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      DOI: 10.7554/eLife.65421

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    ncbi.nlm.nih.gov/pmc/articles/PMC8865852/
  32. elifesciences.org elifesciences.org
    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
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    1. scibot 03 Mar 2022
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      DOI: 10.7554/eLife.66869

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    elifesciences.org/articles/66869
  33. www.sciencedirect.com www.sciencedirect.com
    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
    2
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    sciencedirect.com/science/article/pii/S1534580722000703
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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    sciencedirect.com/science/article/pii/S2211124722001498
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    Recruitment of DNA to tumor-derived microvesicles
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    sciencedirect.com/science/article/pii/S221112472200170X
  36. Feb 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Generation of a pooled shRNA library for functional genomics screens
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    sciencedirect.com/science/article/pii/S2666166722000636
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    The transcriptional profile of adipose-derived stromal cells (ASC) mirrors the whitening of adipose tissue with age
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    sciencedirect.com/science/article/pii/S0171933522000097
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    High-throughput identification of autoantibodies that target the human exoproteome
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      DOI: 10.1016/j.crmeth.2022.100172

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    sciencedirect.com/science/article/pii/S2667237522000248
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    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
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    sciencedirect.com/science/article/pii/S1097276522000570
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    An AMPKα2-specific phospho-switch controls lysosomal targeting for activation
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    sciencedirect.com/science/article/pii/S2211124722000869
  42. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TBK1-METTL3 axis facilitates antiviral immunity
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    pubmed.ncbi.nlm.nih.gov/35172162/
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    Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing
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  44. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
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    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
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      DOI: 10.1016/j.celrep.2022.110388

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      plasmid_12

      DOI: 10.1016/j.celrep.2022.110388

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    sciencedirect.com/science/article/pii/S2211124722001097
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C-type natriuretic peptide-induced PKA activation promotes endochondral bone formation in hypertrophic chondrocytes
    1
    1. scibot 12 Feb 2022
      RRID:Addgene_12260

      DOI: 10.1210/endocr/bqac005

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    ncbi.nlm.nih.gov/pmc/articles/PMC8826897/
  47. www.sciencedirect.com www.sciencedirect.com
    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
    2
    1. scibot 11 Feb 2022
      plasmid_12260

      DOI: 10.1016/j.isci.2022.103806

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      plasmid_12260

      DOI: 10.1016/j.isci.2022.103806

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    sciencedirect.com/science/article/pii/S2589004222000761
  48. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
    2
    1. scibot 11 Feb 2022
      12260

      DOI: 10.1016/j.celrep.2022.110349

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      12260

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    pubmed.ncbi.nlm.nih.gov/35139382/
  49. www.sciencedirect.com www.sciencedirect.com
    Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
    2
    1. scibot 11 Feb 2022
      Addgene# 12260

      DOI: 10.1016/j.celrep.2022.110343

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    2. scibot 09 Feb 2022
      Addgene# 12260

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    sciencedirect.com/science/article/pii/S2211124722000596
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing is an alternate oncogenic pathway activation mechanism in glioma
    2
    1. scibot 11 Feb 2022
      Addgene_12260

      DOI: 10.1038/s41467-022-28253-4

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      Addgene_12260

      DOI: 10.1038/s41467-022-28253-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC8803922/
  51. www.sciencedirect.com www.sciencedirect.com
    Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants
    2
    1. scibot 11 Feb 2022
      Plasmid_12260

      DOI: 10.1016/j.isci.2022.103810

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      Plasmid_12260

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    sciencedirect.com/science/article/pii/S2589004222000803
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts
    1
    1. scibot 08 Feb 2022
      RRID:Addgene_12260

      DOI: 10.3389/fcell.2021.797927

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    ncbi.nlm.nih.gov/pmc/articles/PMC8815860/
  53. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network
    1
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      RRID:Addgene_12260

      DOI: 10.1016/j.ebiom.2022.103861

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    sciencedirect.com/science/article/pii/S2352396422000457
  54. www.sciencedirect.com www.sciencedirect.com
    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2022.01.003

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    sciencedirect.com/science/article/pii/S1535610822000058
  55. www.sciencedirect.com www.sciencedirect.com
    Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties
    1
    1. scibot 02 Feb 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2022.103759

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    sciencedirect.com/science/article/pii/S2589004222000293
  56. www.sciencedirect.com www.sciencedirect.com
    Multiple PDE3A modulators act as molecular glues promoting PDE3A-SLFN12 interaction and induce SLFN12 dephosphorylation and cell death
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      Addgene_12260

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    sciencedirect.com/science/article/pii/S245194562200006X
  57. www.sciencedirect.com www.sciencedirect.com
    Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death
    1
    1. scibot 02 Feb 2022
      Addgene_12260

      DOI: 10.1016/j.celrep.2022.110316

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    sciencedirect.com/science/article/pii/S2211124722000274
  58. www.sciencedirect.com www.sciencedirect.com
    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
    1
    1. scibot 02 Feb 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.110329

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    sciencedirect.com/science/article/pii/S2211124722000456
  59. www.sciencedirect.com www.sciencedirect.com
    Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
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    1. scibot 02 Feb 2022
      RRID:Addgene_12

      DOI: 10.1016/j.tranon.2022.101354

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    sciencedirect.com/science/article/pii/S193652332200016X
  60. Jan 2022
  61. www.sciencedirect.com www.sciencedirect.com
    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
    1
    1. scibot 29 Jan 2022
      plasmid_12260

      DOI: 10.1016/j.molcel.2021.12.038

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    sciencedirect.com/science/article/pii/S1097276521011436
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis
    1
    1. scibot 28 Jan 2022
      RRID:Addgene_12260

      DOI: 10.3389/fcell.2021.779169

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    ncbi.nlm.nih.gov/pmc/articles/PMC8790513/
  63. www.sciencedirect.com www.sciencedirect.com
    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
    1
    1. scibot 26 Jan 2022
      AddgeneCat#12260

      DOI: 10.1016/j.celrep.2022.110302

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    sciencedirect.com/science/article/pii/S2211124722000146
  64. www.sciencedirect.com www.sciencedirect.com
    The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression
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      RRID:Addgene_12260

      DOI: 10.1016/j.jaci.2021.11.019

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    sciencedirect.com/science/article/pii/S0091674921025811
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors
    1
    1. scibot 22 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1002/advs.202104344

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    onlinelibrary.wiley.com/doi/10.1002/advs.202104344
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II
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    1. scibot 22 Jan 2022
      RRID:Addgene_12260

      DOI: 10.3389/fimmu.2021.774491

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    ncbi.nlm.nih.gov/pmc/articles/PMC8770530/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
    1
    1. scibot 22 Jan 2022
      RRID:Addgene_12260

      DOI: 10.3390/cancers14020339

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    ncbi.nlm.nih.gov/pmc/articles/PMC8773829/
  68. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
    1
    1. scibot 16 Jan 2022
      AddgeneCat#12260

      DOI: 10.1016/j.celrep.2021.110236

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    sciencedirect.com/science/article/pii/S2211124721017459
  69. www.sciencedirect.com www.sciencedirect.com
    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
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    1. scibot 16 Jan 2022
      AddgeneCat# 12260

      DOI: 10.1016/j.crmeth.2021.100153

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    sciencedirect.com/science/article/pii/S2667237521002307
  70. www.nature.com www.nature.com
    Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins
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      RRID:Addgene_12260

      DOI: 10.1038/s42003-021-02953-x

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    nature.com/articles/s42003-021-02953-x
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans
    1
    1. scibot 15 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2021.12.026

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    ncbi.nlm.nih.gov/pmc/articles/PMC8695127/
  72. www.sciencedirect.com www.sciencedirect.com
    Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
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      Addgene12260

      DOI: 10.1016/j.cell.2021.12.021

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    sciencedirect.com/science/article/pii/S0092867421014847
  73. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    2
    1. scibot 12 Jan 2022
      Addgene plasmid # 12260

      DOI: 10.1016/j.celrep.2021.110233

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      plasmid_12260

      DOI: 10.1016/j.celrep.2021.110233

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    sciencedirect.com/science/article/pii/S2211124721017423
  74. www.sciencedirect.com www.sciencedirect.com
    Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
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    1. scibot 12 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2021.103621

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    sciencedirect.com/science/article/pii/S2589004221015911
  75. www.sciencedirect.com www.sciencedirect.com
    Identification and functional characterization of transcriptional activators in human cells
    1
    1. scibot 11 Jan 2022
      Addgene_12260

      DOI: 10.1016/j.molcel.2021.12.008

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    sciencedirect.com/science/article/pii/S1097276521010704
  76. www.sciencedirect.com www.sciencedirect.com
    C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane
    1
    1. scibot 08 Jan 2022
      plasmid_12

      DOI: 10.1016/j.celrep.2021.110226

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    sciencedirect.com/science/article/pii/S2211124721017307
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bivalent Nanoparticle Vaccine Exhibits Potent Cross-protection against the Variants of SARS-CoV-2
    1
    1. scibot 07 Jan 2022
      Plasmid_12260

      DOI: 10.1016/j.celrep.2021.110256

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    ncbi.nlm.nih.gov/pmc/articles/PMC8695190/
  78. www.sciencedirect.com www.sciencedirect.com
    Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice
    1
    1. scibot 05 Jan 2022
      12260

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    sciencedirect.com/science/article/pii/S2352396421005971
  79. www.sciencedirect.com www.sciencedirect.com
    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
    1
    1. scibot 05 Jan 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.110197

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    sciencedirect.com/science/article/pii/S2211124721017010
  80. Dec 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
    1
    1. scibot 29 Dec 2021
      plasmid_12260

      DOI: 10.1016/j.isci.2021.103605

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    sciencedirect.com/science/article/pii/S2589004221015753
  82. www.cell.com www.cell.com
    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
    1
    1. scibot 29 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.110155

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    cell.com/cell-reports/fulltext/S2211-1247(21)01651-X
  83. mct.aacrjournals.org mct.aacrjournals.org
    Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization
    1
    1. scibot 22 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1158/1535-7163.MCT-20-1034

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    mct.aacrjournals.org/content/20/11/2228
  84. link.springer.com link.springer.com
    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
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      RRID:Addgene_12260

      DOI: 10.1186/s40170-021-00277-2

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    link.springer.com/article/10.1186/s40170-021-00277-2
  85. www.sciencedirect.com www.sciencedirect.com
    Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1
    1
    1. scibot 15 Dec 2021
      Plasmid_12260

      DOI: 10.1016/j.celrep.2021.110104

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity
    1
    1. scibot 11 Dec 2021
      AddgenePlasmid# 12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633987/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
    1
    1. scibot 11 Dec 2021
      plasmid_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC8605023/
  88. elifesciences.org elifesciences.org
    Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
    1
    1. scibot 11 Dec 2021
      Plasmid_12260

      DOI: 10.7554/eLife.73027

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    elifesciences.org/articles/73027
  89. www.sciencedirect.com www.sciencedirect.com
    Structure, mechanism, and inhibition of Hedgehog acyltransferase
    1
    1. scibot 10 Dec 2021
      plasmid_12260

      DOI: 10.1016/j.molcel.2021.11.018

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    sciencedirect.com/science/article/pii/S1097276521009989
  90. www.sciencedirect.com www.sciencedirect.com
    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
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    1. scibot 08 Dec 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.immuni.2021.11.006

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    sciencedirect.com/science/article/pii/S1074761321004970
  91. www.sciencedirect.com www.sciencedirect.com
    Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation
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    1. scibot 07 Dec 2021
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S0021925821012680
  92. www.sciencedirect.com www.sciencedirect.com
    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
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    1. scibot 03 Dec 2021
      Cat#12260

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    sciencedirect.com/science/article/pii/S009286742101326X
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling
    1
    1. scibot 02 Dec 2021
      AddgenePlasmid #12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC8610276/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetically Edited Hepatic Cells Expressing the NTCP-S267F Variant are Resistant to Hepatitis B Virus Infection
    1
    1. scibot 02 Dec 2021
      Addgene_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608598/
  95. Nov 2021
  96. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
    1
    1. scibot 30 Nov 2021
      Cat# 12260

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  97. www.sciencedirect.com www.sciencedirect.com
    Immuno-transcriptomic profiling of extracranial pediatric solid malignancies
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    1. scibot 30 Nov 2021
      Addgene_12260

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    sciencedirect.com/science/article/pii/S2211124721015333
  98. www.sciencedirect.com www.sciencedirect.com
    Deciphering cell signaling networks with massively multiplexed biosensor barcoding
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    1. scibot 30 Nov 2021
      plasmid_12260

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    sciencedirect.com/science/article/pii/S0092867421013209
  99. elifesciences.org elifesciences.org
    Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
    1
    1. scibot 24 Nov 2021
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      DOI: 10.7554/eLife.65109

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    elifesciences.org/articles/65109
  100. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    1. scibot 24 Nov 2021
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    sciencedirect.com/science/article/pii/S2211124721015424
  101. www.sciencedirect.com www.sciencedirect.com
    PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ
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    1. scibot 23 Nov 2021
      Addgene, Cat# 12260

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    sciencedirect.com/science/article/pii/S2451945621004785
  102. www.sciencedirect.com www.sciencedirect.com
    Effective chimeric antigen receptor T-cells (CAR-Ts) against SARS-CoV-2
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    1. scibot 18 Nov 2021
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S2589004221012645
  103. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
      plasmid_12260

      DOI: 10.1016/j.celrep.2021.109979

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    sciencedirect.com/science/article/pii/S2211124721014583
  104. www.sciencedirect.com www.sciencedirect.com
    Modulating mesendoderm competence during human germ layer differentiation
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    1. scibot 10 Nov 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109990

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    sciencedirect.com/science/article/pii/S2211124721014698
  105. www.sciencedirect.com www.sciencedirect.com
    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
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    1. scibot 10 Nov 2021
      Plasmid_12260

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    sciencedirect.com/science/article/pii/S2211124721014601
  106. www.nature.com www.nature.com
    RNA-responsive elements for eukaryotic translational control
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    1. scibot 06 Nov 2021
      RRID:Addgene_12260

      DOI: 10.1038/s41587-021-01068-2

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    nature.com/articles/s41587-021-01068-2
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Improved CRISPR/dCas9 Interference Tool for Neuronal Gene Suppression
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    1. scibot 05 Nov 2021
      plasmid_12260

      DOI: 10.3389/fgeed.2020.00009

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    ncbi.nlm.nih.gov/pmc/articles/PMC8525373/
  108. www.sciencedirect.com www.sciencedirect.com
    A multi-omic single-cell landscape of human gynecologic malignancies
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    1. scibot 05 Nov 2021
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S109727652100842X
  109. Oct 2021
  110. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
    1
    1. scibot 29 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2021.103224

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    sciencedirect.com/science/article/pii/S2589004221011925
  111. www.jneurosci.org www.jneurosci.org
    Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells
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    1. scibot 27 Oct 2021
      Addgene_12260

      DOI: 10.1523/JNEUROSCI.3243-20.2021

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    jneurosci.org/content/41/42/8710
  112. www.sciencedirect.com www.sciencedirect.com
    GCN2 adapts protein synthesis to scavenging-dependent growth
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    1. scibot 27 Oct 2021
      Addgene_12260

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    sciencedirect.com/science/article/pii/S2405471221003823
  113. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
    1
    1. scibot 23 Oct 2021
      12260

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    sciencedirect.com/science/article/pii/S1097276521008340
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope
    1
    1. scibot 23 Oct 2021
      RRID:Addgene_12260

      DOI: 10.7554/eLife.65672

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    ncbi.nlm.nih.gov/pmc/articles/PMC8523159/
  115. www.sciencedirect.com www.sciencedirect.com
    Exocyst complex mediates recycling of internal cilia
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    1. scibot 22 Oct 2021
      RRID:Addgene 12260

      DOI: 10.1016/j.cub.2021.09.067

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    sciencedirect.com/science/article/pii/S0960982221013233
  116. www.sciencedirect.com www.sciencedirect.com
    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    1. scibot 21 Oct 2021
      12260

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    sciencedirect.com/science/article/pii/S109727652100798X
  117. www.sciencedirect.com www.sciencedirect.com
    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
    1
    1. scibot 21 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109856

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    sciencedirect.com/science/article/pii/S2211124721013231
  118. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas
    1
    1. scibot 21 Oct 2021
      Addgene_12260

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    sciencedirect.com/science/article/pii/S2211124721013401
  119. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 20 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1111/bph.15631

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15631
  120. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
    1
    1. scibot 14 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.jbc.2021.101291

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    sciencedirect.com/science/article/pii/S0021925821010966
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A highly potent antibody effective against SARS-CoV-2 variants of concern
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    1. scibot 13 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.109814

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    ncbi.nlm.nih.gov/pmc/articles/PMC8452523/
  122. www.sciencedirect.com www.sciencedirect.com
    Cancer cell immune mimicry delineates onco-immunologic modulation
    1
    1. scibot 11 Oct 2021
      Addgene_12260

      DOI: 10.1016/j.isci.2021.103133

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    sciencedirect.com/science/article/pii/S2589004221011019
  123. www.sciencedirect.com www.sciencedirect.com
    Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines
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    1. scibot 05 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.xpro.2021.100870

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    sciencedirect.com/science/article/pii/S2666166721005761
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system
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    1. scibot 02 Oct 2021
      RRID:Addgene_12260

      DOI: 10.1038/s41598-021-98657-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
  125. Sep 2021
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells
    1
    1. scibot 30 Sep 2021
      RRID:Addgene_12260

      DOI: 10.1111/gtc.12893

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    onlinelibrary.wiley.com/doi/10.1111/gtc.12893
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
    1
    1. scibot 28 Sep 2021
      RRID:Addgene_12260

      DOI: 10.1158/2643-3230.bcd-21-0012

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    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ observation of mitochondrial biogenesis as the early event of apoptosis
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      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2021.103038

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    ncbi.nlm.nih.gov/pmc/articles/PMC8441175/
  129. www.sciencedirect.com www.sciencedirect.com
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
    1
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      DOI: 10.1016/j.xcrm.2021.100394

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    sciencedirect.com/science/article/pii/S2666379121002524
  130. www.sciencedirect.com www.sciencedirect.com
    Lrp1 is a host entry factor for Rift Valley fever virus
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    1. scibot 24 Sep 2021
      RRID: Addgene_12260

      DOI: 10.1016/j.cell.2021.09.001

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    sciencedirect.com/science/article/pii/S0092867421010485
  131. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
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    1. scibot 24 Sep 2021
      12260

      DOI: 10.1016/j.molcel.2021.08.039

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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Assessing the Wnt-reactivity of cytonemes of mouse embryonic stem cells using a bioengineering approach
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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    Pro-inflammatory and proliferative microglia drive progression of glioblastoma
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFP36L2 Role in Thyroid Functionality
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  137. www.sciencedirect.com www.sciencedirect.com
    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2
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    Cilium induction triggers differentiation of glioma stem cells
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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  141. link.springer.com link.springer.com
    Methods for Quantitative Assessment of <IndexTerm ID="ITerm1">Protein Degradation</IndexTerm>
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy
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    Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome
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    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
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  146. Aug 2021
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    Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
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  148. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy
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    A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
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  154. www.sciencedirect.com www.sciencedirect.com
    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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  155. www.embopress.org www.embopress.org
    The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder
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    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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    Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
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    Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration
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    Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide
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    Identifying chemogenetic interactions from CRISPR screens with drugZ
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  162. www.biorxiv.org www.biorxiv.org
    Scalable, FACS-Free Genome-Wide Phenotypic Screening
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  164. elifesciences.org elifesciences.org
    Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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    Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
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  169. www.sciencedirect.com www.sciencedirect.com
    Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
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  171. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  173. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects
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      Addgene catalog co. 12260

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  175. www.sciencedirect.com www.sciencedirect.com
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  176. www.nature.com www.nature.com
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    nature.com/articles/s41598-018-37940-6
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5446411/
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
  179. elifesciences.org elifesciences.org
    Subcellular drug targeting illuminates local kinase action
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      RRID:Addgene_12260

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  180. www.sciencedirect.com www.sciencedirect.com
    Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats
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    sciencedirect.com/science/article/pii/S1931312821003383
  181. www.sciencedirect.com www.sciencedirect.com
    Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells
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      Plasmid_12260

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    sciencedirect.com/science/article/pii/S1550413121003314
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    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S1535610821003846
  183. www.mdpi.com www.mdpi.com
    Nanog, in Cooperation with AP1, Increases the Expression of E6/E7 Oncogenes from HPV Types 16/18
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    mdpi.com/1999-4915/13/8/1482
  184. www.sciencedirect.com www.sciencedirect.com
    The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation
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      12260

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    sciencedirect.com/science/article/pii/S2211124721008913
  185. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S0092867418315630
  186. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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      plasmid_12260

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    sciencedirect.com/science/article/pii/S1931312818305584
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5495570/
  188. www.sciencedirect.com www.sciencedirect.com
    Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells
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    sciencedirect.com/science/article/pii/S2451945621003512
  189. www.sciencedirect.com www.sciencedirect.com
    In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment
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      plasmid_12260

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    sciencedirect.com/science/article/pii/S0092867417315106
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      Plasmid_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC5822422/
  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation
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    onlinelibrary.wiley.com/doi/10.1002/glia.24066
  192. jitc.biomedcentral.com jitc.biomedcentral.com
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    jitc.biomedcentral.com/articles/10.1186/s40425-019-0575-3
  193. www.nature.com www.nature.com
    Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts
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    nature.com/articles/s41598-019-52294-3
  194. www.biorxiv.org www.biorxiv.org
    MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
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    biorxiv.org/content/10.1101/107201v1
  195. www.sciencedirect.com www.sciencedirect.com
    Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
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    sciencedirect.com/science/article/pii/S2211124721008834
  196. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Design and construction of a recombinant lentiviral vector with specific tropism to human epidermal growth factor‐overexpressed cancer cells: developing a new retargeting system for lentivirus vectors
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      RRID:Addgene_12260

      DOI: 10.1002/jgm.3095

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    onlinelibrary.wiley.com/doi/full/10.1002/jgm.3095
  197. Jul 2021
  198. www.sciencedirect.com www.sciencedirect.com
    Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers
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    1. scibot 31 Jul 2021
      Plasmid No. 12260

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    sciencedirect.com/science/article/pii/S009286742100831X
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      plasmid_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC6463631/
  200. www.sciencedirect.com www.sciencedirect.com
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      RRID:Addgene_12260

      DOI: 10.1016/j.stem.2019.02.006

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    sciencedirect.com/science/article/pii/S1934590919300487
  201. www.sciencedirect.com www.sciencedirect.com
    Widespread and Functional RNA Circularization in Localized Prostate Cancer
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      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2019.01.025

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    sciencedirect.com/science/article/pii/S0092867419300583