3,573 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MicroRNA-885-5p regulates cell cycle progression in liver cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373435/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCV2 Infection Upregulates SOCS3 Expression to Facilitate Viral Replication in PK-15 Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390612/
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    Aging-associated DNA methylation of LEF1 modulates inflammation and neurodegenerative pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12408614/
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    Betrixaban is a broad anti-virus inhibitor by activating innate immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12408630/
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    Front-biased activation of the Ras-Rab5-Rac1 loop coordinates collective cell migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12377714/
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    Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12376455/
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    Obesity enhances ovarian cancer chemotherapy efficacy through C1q-mediated tumor targeting and immune activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12372299/
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    Atypical cadherin FAT1 promotes tumorigenesis by suppressing autophagic cell death in glioblastoma under hypoxia or nutrient stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409952/
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    Ablating UNG activity in a mouse model inhibits colorectal cancer growth by increasing tumor immunogenicity
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    Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404763/
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    Intrinsic Properties of the Lymph Node Render It Immunologically Susceptible to Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409284/
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    PKN2 is a dependency of the mesenchymal-like cancer cell state
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
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    PIN1 prolyl isomerase promotes initiation and progression of bladder cancer through the SREBP2-mediated cholesterol biosynthesis pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875963/
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    Resilience and vulnerabilities of tumor cells under purine shortage stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399269/
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    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221223/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR-Cas13d-Mediated Targeting of a Context-Specific Essential Gene Enables Selective Elimination of Uveal Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393512/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    α-catenin phosphorylation is actomyosin-sensitive and required for epithelial barrier functions through Afadin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393524/
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    Endogenous Real Time Imaging Reveals Dynamic Chromosomal Mobility During Ligand-Mediated Transcriptional Burst Events
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393356/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD3 and p300 complex scaffolding by long non-coding RNA LIMD1-AS1 promotes TGF-β-induced breast cancer cell plasticity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12400928/
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    TDP-43 binds to RNA G-quadruplex structure and regulates mRNA stability and translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12407096/
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    Pooled CRISPR screens identifies key regulators of bovine stem cell expansion for cultured meat
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398484/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373898/
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    The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12391391/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived tumoroids from CIC::DUX4 rearranged sarcoma identify MCL1 as a therapeutic target
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370961/
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    Nuclear pore complex dysfunction drives TDP-43 pathology in ALS
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390953/
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    SALSA: a novel flow cytometry assay to detect ascorbate at the single-cell level
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398858/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Syncytial death mediated by oncolytic rVSV-NDV dynamically activates immunogenic apoptosis and necroptosis in human lung cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390950/
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    Metabolomics analysis of SNAT2-deficient cells: Implications for the discovery of selective small-molecule inhibitors of an amino acid transporter
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    Enhance therapeutic efficacy of BiTE (HER2/CD3) for HER2- positive tumors through in vivo expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12410412/
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    Chemogenetic tuning reveals optimal MAPK signaling for cell-fate programming
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    Bifidobacteria-derived exopolysaccharide promotes anti-tumor immunity
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    Targeting YAP/TAZ-TEAD signaling as a therapeutic approach in head and neck squamous cell carcinoma
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    TMT-based proteomics analysis identifies RPLP1 as a key protein target in ursolic acid Inhibition of colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12401778/
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    Cancer Cell‐Secreted miR‐33a Reduces Stress Granule Formation by Targeting Polyamine Metabolism in Stroma to Promote Tumourigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12408367/
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    Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12407345/
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    Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
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    PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma
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    Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics
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    biorxiv.org/content/10.1101/2025.08.27.672586v1
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    Intron retention regulates STAT2 function and predicts immunotherapy response in lung cancer
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    EGFR-induced lncRNA TRIDENT promotes drug resistance in non–small cell lung cancer via phospho-TRIM28-mediated DNA damage repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC11912419/
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    AAV-dCas9 vector unsilences paternal Ube3a in neurons by impeding Ube3a-ATS transcription
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    PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis
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    Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system
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    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
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    A Commander-independent function of COMMD3 in endosomal trafficking
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    elifesciences.org/articles/105264
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    A Polyomavirus-Positive Merkel Cell Carcinoma Mouse Model Supports a Unified Origin for Somatic and Germ Cell Cancers
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    mdpi.com/2072-6694/17/17/2800
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    Cross-species analysis identifies genotype-driven vulnerabilities in lung adenocarcinoma
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    biorxiv.org/content/10.1101/2025.08.24.671070v1
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    Coxsackievirus B infection invokes unique cell-type-specific responses in primary human pancreatic islets
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    K29-Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509817
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    Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems
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    Endogenous fine-mapping and prioritization of functional regulatory elements in complex genetic loci
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    cell.com/cell-genomics/abstract/S2666-979X(25)00238-1
  53. Aug 2025
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    Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity
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    A vascular-associated fibroblastic cell controls pancreatic islet immunity
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    Junctional adhesion molecule C limits glioblastoma stem-like cell invasion by regulating integrin adhesion at the endothelial interface
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    DFFB suppresses interferon to enable cancer persister cell regrowth
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    biorxiv.org/content/10.1101/2025.08.15.670603v1
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    Identification of organelle-specific autophagy regulators from tandem CRISPR screens
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    Evolution of the SARS-CoV-2 spike protein in utilizing host transmembrane serine proteases
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    Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer
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    L1CAM signaling through planar cell polarity generates SOX2+ metastatic progenitors in lung adenocarcinoma
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    biorxiv.org/content/10.1101/2025.08.22.671773v1
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    SCAMP3 is essential for proper formation and function of neutrophil granules
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    biorxiv.org/content/10.1101/2025.08.15.670532v1
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    Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis
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    biorxiv.org/content/10.1101/2025.08.15.670286v1
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    Generation of human embryonic stem cell line expressing dCas9-TET1 fusion protein for epigenetic editing
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    sciencedirect.com/science/article/pii/S1873506125001618
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    Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment
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    nature.com/articles/s43587-025-00940-z
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    ROS-dependent localization of glycolytic enzymes to mitochondria
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    pmc.ncbi.nlm.nih.gov/articles/PMC12359183/
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    Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202502074
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    Cytoplasmic PXR regulates glucose metabolism by binding mRNAs and modulating their stability
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    nature.com/articles/s41594-025-01614-5
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting FSP1 triggers ferroptosis in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363832/
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    C19orf12 inhibits mitochondrial function and enhances the antitumor effects of metformin in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725009349
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    ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis
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    sciencedirect.com/science/article/pii/S1534580725004733
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    E2F1 suppresses Epstein-Barr virus lytic reactivation through cellular and viral transcriptional networks
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    pmc.ncbi.nlm.nih.gov/articles/PMC12349880/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12351401/
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    Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a
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    sciencedirect.com/science/article/pii/S0969212625002667
  75. www.nature.com www.nature.com
    Inhibition of LDHB triggers DNA damage and increases cisplatin sensitivity in pleural mesothelioma
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    nature.com/articles/s41389-025-00571-4
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    Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
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    sciencedirect.com/science/article/pii/S1097276525006148
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glucose transporter 1 is essential to maintain brain endothelial cell homeostasis under hyperglycemia condition | American Journal of Physiology-Cell Physiology | American Physiological Society
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    pmc.ncbi.nlm.nih.gov/articles/PMC12341840/
  78. 52.53.155.43 52.53.155.43
    bneo_neo-2024-000538-main-html.html
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  79. 52.53.155.43 52.53.155.43
    2025.08.06.668996v1.full-html.html
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    52.53.155.43/9762f0542a12c1b879bb3817e6abf20525e5b06e/2025.08.06.668996v1.full-html.html
  80. www.biorxiv.org www.biorxiv.org
    Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression
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    biorxiv.org/content/10.1101/2025.08.05.668679v1
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unlocking ESCC Progression: CCL15-CCR1 Axis Activates AKT/ERK1/2/c-Jun/CDK2 Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12305565/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zinc finger protein 695 facilitates the proliferation of colorectal cancer cells through activation of the NEK2 and PI3K/Akt/mTOR signaling pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12308799/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM5α/Cyclophilin A-Modified MDBK Cells for Lentiviral-Based Gene Editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12298503/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DIRAS1 Drives Oxaliplatin Resistance in Colorectal Cancer via PHB1-Mediated Mitochondrial Homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12292402/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting USP42 induces DNA damage and inhibits cell growth in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289470/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRMT1 oligomerization regulates RNA-binding protein cascade to promote pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12272085/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    As a New Tumor Suppressor Gene, PID1 Activates the AMPK-mTOR Signal to Inhibit the Progression of Bladder Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12302987/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An EGFR Co-Amplified and De Novo Long Noncoding RNA HELDR Promotes Glioblastoma Malignancy through KAT7-Driven Gene Programs
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    TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids
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    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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