2,906 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    Breast Cancer Subtype-Specific Organotropism is Dictated by FOXF2-Regulated Metastatic Dormancy and Recovery
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    1. scibot 17 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-24-0479

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    aacrjournals.org/cancerres/article/85/4/644/751430/Breast-Cancer-Subtype-Specific-Organotropism-Is
  3. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225006923-main-html.html
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    1. scibot 17 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2025.112431

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    52.53.155.43/2822984229a17d4b7b1b3fe18766540ee44d0672/1-s2.0-S2589004225006923-main-html.html
  4. www.sciencedirect.com www.sciencedirect.com
    Rewriting regulatory DNA to dissect and reprogram gene expression
    1
    1. scibot 17 Apr 2025
      Addgene_12260

      DOI: 10.1016/j.cell.2025.03.034

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    sciencedirect.com/science/article/pii/S0092867425003526
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SRPK1 Activation Facilitates Gli3S664 Phosphorylation and Promotes Metastasis in Esophageal Squamous Cell Carcinoma
    1
    1. scibot 17 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1002/mc.23913

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23913
  6. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-dependent charge blocks regulate the relaxation of nuclear speckle networks
    1
    1. scibot 15 Apr 2025
      Addgene:12260

      DOI: 10.1016/j.molcel.2025.03.016

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    sciencedirect.com/science/article/pii/S1097276525002606
  7. www.sciencedirect.com www.sciencedirect.com
    Development of an Hepatitis B Pseudovirus System for Safe and Effective Antiviral Drug Screening
    1
    1. scibot 15 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.microb.2025.100339

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    sciencedirect.com/science/article/pii/S2950194625001074
  8. 52.53.155.43 52.53.155.43
    PDF-html.html
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    1. scibot 13 Apr 2025
      Addgene  plasmid  #12260

      DOI: 10.1016/j.isci.2025.112408

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    52.53.155.43/1d7f3a53d05f85c55a541cebaae421bfbc1ec25f/PDF-html.html
  9. www.sciencedirect.com www.sciencedirect.com
    Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
    1
    1. scibot 11 Apr 2025
      AddgeneCat# 12260

      DOI: 10.1016/j.ccell.2025.03.031

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    sciencedirect.com/science/article/pii/S1535610825001321
  10. www.sciencedirect.com www.sciencedirect.com
    Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence
    1
    1. scibot 11 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.cels.2025.101260

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    sciencedirect.com/science/article/pii/S2405471225000936
  11. Apr 2025
  12. www.nature.com www.nature.com
    Heritable maintenance of chromatin modifications confers transcriptional memory of interferon-γ signaling
    1
    1. scibot 10 Apr 2025
      Addgene, cat. no. 12260

      DOI: 10.1038/s41594-025-01522-8

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    nature.com/articles/s41594-025-01522-8
  13. www.sciencedirect.com www.sciencedirect.com
    MLKL activity requires a splicing-regulated, druggable intramolecular interaction
    1
    1. scibot 10 Apr 2025
      AddgeneCat#12260

      DOI: 10.1016/j.molcel.2025.03.015

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    sciencedirect.com/science/article/pii/S109727652500259X
  14. www.sciencedirect.com www.sciencedirect.com
    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
    1
    1. scibot 08 Apr 2025
      AddgeneCat# 12260

      DOI: 10.1016/j.celrep.2025.115541

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    sciencedirect.com/science/article/pii/S2211124725003122
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.7554/eLife.101973

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    pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glycosylated Receptor-Binding-Domain-Targeting Mucosal Vaccines Protect Against SARS-CoV-2 Omicron and MERS-CoV
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.3390/vaccines13030293

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    pmc.ncbi.nlm.nih.gov/articles/PMC11946235/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Pseudotyped Replication-Deficient VSV with Spike from PEDV Induces Neutralizing Antibody Against PEDV
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.3390/vaccines13030223

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    pmc.ncbi.nlm.nih.gov/articles/PMC11946067/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Infectivity and Pathogenicity Characteristics of a Recombinant Porcine Epidemic Diarrhea Virus, CHFJFQ
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.3390/v17030401

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    pmc.ncbi.nlm.nih.gov/articles/PMC11945473/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay Between TGFβ1 Signaling and Cancer-Testis Antigen MAGEB2: A New Thorn in Cancer’s Side?
    1
    1. scibot 07 Apr 2025
      pSPAX

      DOI: 10.3390/ijms26062448

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    pmc.ncbi.nlm.nih.gov/articles/PMC11942090/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glycosylation Regulation by TMEM230 in Aging and Autoimmunity
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.3390/ijms26062412

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    pmc.ncbi.nlm.nih.gov/articles/PMC11942208/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell sequencing combined with urinary multi-omics analysis reveals that the non-invasive biomarker PRDX5 regulates bladder cancer progression through ferroptosis signaling
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.1186/s12885-025-13881-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11931876/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular control of PDPNhi macrophage subset induction by ADAP as a host defense in sepsis
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1172/jci.insight.186456

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    pmc.ncbi.nlm.nih.gov/articles/PMC11949065/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-scale CRISPR/Cas9 screening reveals the role of PSMD4 in colibactin-mediated cell cycle arrest
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.1128/msphere.00692-24

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    pmc.ncbi.nlm.nih.gov/articles/PMC11934320/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila and human Headcase define a new family of ribonucleotide granule proteins required for stress response
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1126/sciadv.ads2086

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    pmc.ncbi.nlm.nih.gov/articles/PMC11952099/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CREB-family transcription factors and vasopressin-mediated regulation of Aqp2 gene transcription
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.1101/2025.03.10.642395

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    pmc.ncbi.nlm.nih.gov/articles/PMC11952463/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Light-induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1093/nar/gkaf213

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    pmc.ncbi.nlm.nih.gov/articles/PMC11925727/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody reactivity against EBNA1 and GlialCAM differentiates multiple sclerosis patients from healthy controls
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1073/pnas.2424986122

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    pmc.ncbi.nlm.nih.gov/articles/PMC11929495/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    G0S2 modulates normal vitreous-induced proliferation in endothelial cells
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s42003-025-07955-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11971441/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m6A modification regulates cell proliferation via reprogramming the balance between glycolysis and pentose phosphate pathway
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s42003-025-07937-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11947274/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multimodal SARS-CoV-2 interactome sketches the virus-host spatial organization
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s42003-025-07933-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11947133/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic constraint of human telomere length by nucleotide salvage efficiency
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41467-025-58221-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11950188/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41467-025-58035-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11937434/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41467-025-58032-w

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    pmc.ncbi.nlm.nih.gov/articles/PMC11937597/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41467-025-57503-4

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    pmc.ncbi.nlm.nih.gov/articles/PMC11937471/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41419-025-07537-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11929817/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41417-025-00874-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11946898/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1038/s41392-025-02180-4

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    pmc.ncbi.nlm.nih.gov/articles/PMC11926384/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1016/j.xcrm.2025.102021

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    pmc.ncbi.nlm.nih.gov/articles/PMC11970383/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual CARM1-and IKZF3-targeting: A novel approach to multiple myeloma therapy synergy between CARM1 inhibition and IMiDs
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.1016/j.omton.2025.200952

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    pmc.ncbi.nlm.nih.gov/articles/PMC11930131/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HRP2 regulating MICU1-mediated Ca2+ overload to dictate chemoresistance of multiple myeloma
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.1016/j.neo.2025.101150

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    pmc.ncbi.nlm.nih.gov/articles/PMC11930454/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCCTC-binding factor N-terminal domain regulates clustered protocadherin gene expression by enhancing cohesin processivity[image]
    1
    1. scibot 07 Apr 2025
      12,260

      DOI: 10.1016/j.jbc.2025.108337

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    pmc.ncbi.nlm.nih.gov/articles/PMC11968269/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1007/s00432-025-06168-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11926012/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioinformatics Identification of Lactate‐Associated Genes in Hepatocellular Carcinoma: G6PD's Role in Immune Modulation
    1
    1. scibot 07 Apr 2025
      12260

      DOI: 10.1002/cam4.70801

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    pmc.ncbi.nlm.nih.gov/articles/PMC11927016/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KPNA5 Suppresses Malignant Progression of Ovarian Cancer Through Importing the PTPN4 Into the Nucleus
    1
    1. scibot 07 Apr 2025
      psPAX2

      DOI: 10.1002/cam4.70731

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    pmc.ncbi.nlm.nih.gov/articles/PMC11947769/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GNE‐317 Reverses MSN‐Mediated Proneural‐to‐Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR
    1
    1. scibot 07 Apr 2025
      PAX2

      DOI: 10.1002/advs.202412517

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    pmc.ncbi.nlm.nih.gov/articles/PMC11948001/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer
    1
    1. scibot 07 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1186/s12967-025-06258-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11971752/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antigenic cancer persister cells survive direct T cell attack
    1
    1. scibot 07 Apr 2025
      Addgene_12260

      DOI: 10.1101/2025.03.14.643359

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    pmc.ncbi.nlm.nih.gov/articles/PMC11956947/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma
    1
    1. scibot 07 Apr 2025
      plasmid_12260

      DOI: 10.1038/s41419-025-07587-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11968822/
  49. www.sciencedirect.com www.sciencedirect.com
    Harmine promotes axon regeneration through enhancing glucose metabolism
    1
    1. scibot 07 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.jbc.2025.108254

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    sciencedirect.com/science/article/pii/S0021925825001012
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI(3,4,5)P3-mediated Cdc42 activation regulates macrophage podosome assembly
    1
    1. scibot 07 Apr 2025
      Addgene_12260

      DOI: 10.1007/s00018-025-05664-2

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    pmc.ncbi.nlm.nih.gov/articles/PMC11933580/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screens with trastuzumab emtansine in HER2-positive breast cancer cell lines reveal new insights into drug resistance
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1186/s13058-025-02000-1

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    pmc.ncbi.nlm.nih.gov/articles/PMC11959757/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NEDD4 E3 ligase-catalyzed NAMPT ubiquitination and autophagy activation are essential for pyroptosis-independent NAMPT secretion in human monocytes
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1186/s12964-025-02164-5

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    pmc.ncbi.nlm.nih.gov/articles/PMC11956250/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Retinoic acid enhances γδ T cell cytotoxicity in nasopharyngeal carcinoma by reversing immune exhaustion
    1
    1. scibot 05 Apr 2025
      12,260

      DOI: 10.1186/s12964-025-02161-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11955114/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell multi-omics analysis reveals the mechanism of action of a novel antioxidant polyphenol nanoparticle loaded with STAT3 agonist in mediating cardiomyocyte ferroptosis to ameliorate age-related heart failure
    1
    1. scibot 05 Apr 2025
      12,260

      DOI: 10.1186/s12951-025-03317-x

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    pmc.ncbi.nlm.nih.gov/articles/PMC11955111/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C1Q+ TPP1+ macrophages promote colon cancer progression through SETD8-driven p53 methylation
    1
    1. scibot 05 Apr 2025
      12,260

      DOI: 10.1186/s12943-025-02293-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11956498/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1172/JCI177724

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    pmc.ncbi.nlm.nih.gov/articles/PMC11957690/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody‐Dependent Cellular Cytotoxicity of iPS Cell‐Derived Natural Killer T Cells by Anti‐GD2 mAb for Neuroblastoma
    1
    1. scibot 05 Apr 2025
      psPAX2

      DOI: 10.1111/cas.70008

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    pmc.ncbi.nlm.nih.gov/articles/PMC11967243/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1101/2025.03.12.642800

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    pmc.ncbi.nlm.nih.gov/articles/PMC11952432/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Advanced hydrogel mesh platform with neural stem cells and human umbilical vein endothelial cells for enhanced axonal regeneration
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1063/5.0244057

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    pmc.ncbi.nlm.nih.gov/articles/PMC11964475/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The impact of a high fat diet and platelet activation on pre-metastatic niche formation
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1038/s41467-025-57938-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11965330/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1038/s41467-025-57477-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC11965392/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A highland-adaptation variant near MCUR1 reduces its transcription and attenuates erythrogenesis in Tibetans
    1
    1. scibot 05 Apr 2025
      psPAX2

      DOI: 10.1016/j.xgen.2025.100782

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    pmc.ncbi.nlm.nih.gov/articles/PMC11960549/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Papillomavirus-like particles as vectors for ex vivo gene therapy of the skin
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1016/j.omtn.2025.102501

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    pmc.ncbi.nlm.nih.gov/articles/PMC11960642/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VIPAS39 confers ferroptosis resistance in epithelial ovarian cancer through exporting ACSL4
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1016/j.ebiom.2025.105646

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    pmc.ncbi.nlm.nih.gov/articles/PMC11957506/
  65. www.sciencedirect.com www.sciencedirect.com
    RAF1 kinase contributes to autophagic lysosome reformation
    1
    1. scibot 05 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2025.115490

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    sciencedirect.com/science/article/pii/S221112472500261X
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    YY1-induced transcription of AKR1C3 activates the Hedgehog signalling pathway to enhance lenalidomide resistance and glycolytic activity in multiple myeloma cells
    1
    1. scibot 05 Apr 2025
      12,260

      DOI: 10.1007/s10238-025-01619-w

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    pmc.ncbi.nlm.nih.gov/articles/PMC11954848/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Siglec-15 is a putative receptor for porcine epidemic diarrhea virus infection
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1007/s00018-025-05672-2

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    pmc.ncbi.nlm.nih.gov/articles/PMC11965083/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLO2.1/NALCN Functional Complex Activity in Mouse Myometrial Smooth Muscle Cells During Pregnancy
    1
    1. scibot 05 Apr 2025
      12260

      DOI: 10.1002/jcp.70024

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    pmc.ncbi.nlm.nih.gov/articles/PMC11962242/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tribbles Pseudokinase 3 Converts Sorafenib Therapy to Neutrophil‐Mediated Lung Metastasis in Hepatocellular Carcinoma
    1
    1. scibot 05 Apr 2025
      12 260

      DOI: 10.1002/advs.202413682

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    pmc.ncbi.nlm.nih.gov/articles/PMC11967757/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The MFN2 Q367H variant reveals a novel pathomechanism connected to mtDNA-mediated inflammation
    1
    1. scibot 05 Apr 2025
      plasmid_12260

      DOI: 10.26508/lsa.202402921

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    pmc.ncbi.nlm.nih.gov/articles/PMC11966011/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HTLV-1 Tax induces PINK1-Parkin-dependent mitophagy to mitigate activation of the cGAS-STING pathway
    1
    1. scibot 05 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1101/2025.03.15.643451

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    pmc.ncbi.nlm.nih.gov/articles/PMC11952555/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delta-catenin is required for cell proliferation in virus positive Merkel cell carcinoma cell lines but not in human fibroblasts
    1
    1. scibot 05 Apr 2025
      Addgene_12260

      DOI: 10.1101/2025.03.12.642815

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    pmc.ncbi.nlm.nih.gov/articles/PMC11952379/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circadian clock features define novel subtypes among breast cancer cells and shape drug sensitivity
    1
    1. scibot 05 Apr 2025
      Addgene_12260

      DOI: 10.1038/s44320-025-00092-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11965565/
  74. www.sciencedirect.com www.sciencedirect.com
    A nuclear RNA degradation code is recognized by PAXT for eukaryotic transcriptome surveillance
    1
    1. scibot 05 Apr 2025
      plasmid_12260

      DOI: 10.1016/j.molcel.2025.03.010

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    sciencedirect.com/science/article/pii/S1097276525002035
  75. www.sciencedirect.com www.sciencedirect.com
    An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation
    1
    1. scibot 05 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2025.03.006

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    sciencedirect.com/science/article/pii/S1097276525001996
  76. www.sciencedirect.com www.sciencedirect.com
    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
    1
    1. scibot 05 Apr 2025
      Addgene_12260

      DOI: 10.1016/j.cell.2025.03.029

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    sciencedirect.com/science/article/pii/S0092867425003472
  77. www.sciencedirect.com www.sciencedirect.com
    Structural basis for plasticity in receptor engagement by an encephalitic alphavirus
    1
    1. scibot 05 Apr 2025
      Addgene_12260

      DOI: 10.1016/j.cell.2025.02.036

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    sciencedirect.com/science/article/pii/S0092867425002727
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer
    1
    1. scibot 04 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1038/s44318-025-00381-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11962125/
  79. 52.53.155.43 52.53.155.43
    Lysosome positioning affects NLRP3 inflammasome activation
    1
    1. scibot 03 Apr 2025
      Cat# 12260

      DOI: 10.1101/2025.03.21.644552

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    52.53.155.43/5e725b42faf6f4894ebfb1897ac6165b04d7cac3/PDF-html.html
  80. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    1. scibot 03 Apr 2025
      RRID:Addgene_12260

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    52.53.155.43/65d1b99ed5d0f367b734e029ffde0892ad535bb6/PDF-html.html
  81. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    1. scibot 03 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.can-24-0749/3563696/can-24-0749.

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    52.53.155.43/73f4a278983fd3a9b93fed6443158024ffc69ddc/PDF-html.html
  82. www.science.org www.science.org
    Reelin marks cocaine-activated striatal neurons, promotes neuronal excitability, and regulates cocaine reward
    1
    1. scibot 02 Apr 2025
      Addgene, plasmid nos. 12260

      DOI: 10.1126/sciadv.ads4441

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    science.org/doi/10.1126/sciadv.ads4441
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A stress-dependent TDP-43 SUMOylation program preserves neuronal function
    1
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      Addgene_12260

      DOI: 10.1186/s13024-025-00826-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11951803/
  84. 52.53.155.43 52.53.155.43
    PDF-html.html
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    1. scibot 02 Apr 2025
      RRID:Addgene_12260

      DOI: 10.1158/2326-6066.cir-24-0737

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    52.53.155.43/6082e85085e2ed08cbf86aa32472ba192b5c95f0/PDF-html.html
  85. www.cell.com www.cell.com
    SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity
    1
    1. scibot 02 Apr 2025
      Addgene_12260

      DOI: 10.1016/j.celrep.2025.115476

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    cell.com/cell-reports/fulltext/S2211-1247(25)00247-5
  86. www.sciencedirect.com www.sciencedirect.com
    Dicer deficiency affects microglial function during demyelination and impairs remyelination
    2
    1. scibot 01 Apr 2025
      plasmid_12260

      DOI: 10.1016/j.nbd.2025.106879

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    2. scibot 01 Apr 2025
      RRID:Addgene_12

      DOI: 10.1016/j.nbd.2025.106879

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    sciencedirect.com/science/article/pii/S0969996125000956
  87. Mar 2025
  88. www.sciencedirect.com www.sciencedirect.com
    PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth
    1
    1. scibot 29 Mar 2025
      AddgeneCat# 12260

      DOI: 10.1016/j.molcel.2025.02.024

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    sciencedirect.com/science/article/pii/S1097276525001868
  89. www.sciencedirect.com www.sciencedirect.com
    The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2
    1
    1. scibot 29 Mar 2025
      AddgeneCat#12260

      DOI: 10.1016/j.immuni.2025.02.026

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    sciencedirect.com/science/article/pii/S1074761325000937
  90. www.sciencedirect.com www.sciencedirect.com
    The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene
    1
    1. scibot 29 Mar 2025
      12260, Addgene

      DOI: 10.1016/j.celrep.2025.115462

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    sciencedirect.com/science/article/pii/S2211124725002335
  91. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
    1
    1. scibot 29 Mar 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2025.03.001

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    sciencedirect.com/science/article/pii/S1097276525001947
  92. www.sciencedirect.com www.sciencedirect.com
    The HAVCR1-centric host factor network drives Zika virus vertical transmission
    1
    1. scibot 29 Mar 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2025.115464

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    sciencedirect.com/science/article/pii/S2211124725002359
  93. www.sciencedirect.com www.sciencedirect.com
    SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response
    1
    1. scibot 29 Mar 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2025.115434

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    sciencedirect.com/science/article/pii/S2211124725002050
  94. www.sciencedirect.com www.sciencedirect.com
    Translation dysregulation in cancer as a source for targetable antigens
    1
    1. scibot 28 Mar 2025
      RRID: Addgene_12260

      DOI: 10.1016/j.ccell.2025.03.003

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    sciencedirect.com/science/article/pii/S1535610825000820
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Correlative In Situ Cryo-ET Reveals Cellular and Viral Remodeling Associated with Selective HIV-1 Core Nuclear Import
    1
    1. scibot 28 Mar 2025
      RRID:Addgene_12260

      DOI: 10.1101/2025.03.04.641496

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    pmc.ncbi.nlm.nih.gov/articles/PMC11908238/
  96. www.sciencedirect.com www.sciencedirect.com
    Three-dimensional regulatory hubs support oncogenic programs in glioblastoma
    1
    1. scibot 28 Mar 2025
      Addgene_12260

      DOI: 10.1016/j.molcel.2025.03.007

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    sciencedirect.com/science/article/pii/S109727652500200X
  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness
    1
    1. scibot 28 Mar 2025
      Addgene_12260

      DOI: 10.1016/j.isci.2025.111884

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    pmc.ncbi.nlm.nih.gov/articles/PMC11929002/
  98. www.sciencedirect.com www.sciencedirect.com
    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
    1
    1. scibot 28 Mar 2025
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2025.115486

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    sciencedirect.com/science/article/pii/S2211124725002578
  99. www.biorxiv.org www.biorxiv.org
    In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer
    1
    1. scibot 26 Mar 2025
      Addgene plasmid #12260

      DOI: 10.1101/2025.03.20.644389

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    biorxiv.org/content/10.1101/2025.03.20.644389v1
  100. www.biorxiv.org www.biorxiv.org
    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
    2
    1. scibot 24 Mar 2025
      RRID: Addgene_12260

      DOI: 10.1101/2025.03.18.644053

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    2. scibot 24 Mar 2025
      RRID:Addgene_12260

      DOI: 10.1101/2025.03.18.644053

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    biorxiv.org/content/10.1101/2025.03.18.644053v1
  101. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glioblastoma progression is hindered by melatonin-primed mesenchymal stromal cells through dynamic intracellular and extracellular reorganizations
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.7150/thno.104143

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    pmc.ncbi.nlm.nih.gov/articles/PMC11898303/
  102. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia
    1
    1. scibot 23 Mar 2025
      psPAX2

      DOI: 10.7150/thno.100295

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    pmc.ncbi.nlm.nih.gov/articles/PMC11905140/
  103. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.3892/mmr.2025.13481

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    pmc.ncbi.nlm.nih.gov/articles/PMC11905203/
  104. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined Therapy Targeting MET and Pro-HGF Activation Shows Significant Therapeutic Effect Against Liver Metastasis of CRPC
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.3390/ijms26052308

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    pmc.ncbi.nlm.nih.gov/articles/PMC11900290/
  105. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor
    1
    1. scibot 23 Mar 2025
      psPAX2

      DOI: 10.3390/ijms26052237

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    pmc.ncbi.nlm.nih.gov/articles/PMC11899812/
  106. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CXCR4 Inhibition Enhances the Efficacy of CD19 Monoclonal Antibody-Mediated Extermination of B-Cell Lymphoma
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.3390/ijms26052024

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    pmc.ncbi.nlm.nih.gov/articles/PMC11899823/
  107. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    miR-204-5p Protects Nephrin from Enzymatic Degradation in Cultured Mouse Podocytes Treated with Nephrotoxic Serum
    1
    1. scibot 23 Mar 2025
      psPAX2

      DOI: 10.3390/cells14050364

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    pmc.ncbi.nlm.nih.gov/articles/PMC11899291/
  108. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NLRP4 unlocks an NK/macrophages-centered ecosystem to suppress non-small cell lung cancer
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1186/s40364-025-00756-4

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    pmc.ncbi.nlm.nih.gov/articles/PMC11909883/
  109. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA-binding protein SAMD4A targets FGF2 to regulate cardiomyocyte lineage specification from human embryonic stem cells
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1186/s13287-025-04269-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11921648/
  110. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancement of functional insulin-producing cell differentiation from embryonic stem cells through MST1-silencing
    1
    1. scibot 23 Mar 2025
      psPAX2

      DOI: 10.1186/s13098-025-01666-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11924671/
  111. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide screening in human embryonic stem cells identifies genes and pathways involved in the p53 pathway
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1186/s10020-025-01141-5

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    pmc.ncbi.nlm.nih.gov/articles/PMC11907909/
  112. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation of RNA aptamers against chikungunya virus E2 envelope protein
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1128/jvi.02095-24

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    pmc.ncbi.nlm.nih.gov/articles/PMC11915788/
  113. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNF20 dual regulation of MDA5 signaling to maintain immune homeostasis in chickens
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1128/jvi.02008-24

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    pmc.ncbi.nlm.nih.gov/articles/PMC11915864/
  114. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    STT3B promotes porcine epidemic diarrhea virus replication by regulating N-glycosylation of PEDV S protein
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1128/jvi.00018-25

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    pmc.ncbi.nlm.nih.gov/articles/PMC11915848/
  115. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Collaborative role of two distinct cilium-specific cytoskeletal systems in driving Hedgehog-responsive transcription factor trafficking
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1126/sciadv.adt5439

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    pmc.ncbi.nlm.nih.gov/articles/PMC11900865/
  116. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1126/sciadv.adt1241

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    pmc.ncbi.nlm.nih.gov/articles/PMC11900879/
  117. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1126/sciadv.ads8351

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    pmc.ncbi.nlm.nih.gov/articles/PMC11922064/
  118. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Splenic red pulp macrophages eliminate the liver-resistant Streptococcus pneumoniae from the blood circulation of mice
    1
    1. scibot 23 Mar 2025
      psPAX2

      DOI: 10.1126/sciadv.adq6399

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    pmc.ncbi.nlm.nih.gov/articles/PMC11900858/
  119. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1101/2025.02.28.640639

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888458/
  120. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1101/2025.02.24.639755

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888305/
  121. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplexed in vivo base editing identifies functional gene-variant-context interactions
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1101/2025.02.23.639770

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888363/
  122. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resistance to Radiation Enhances Metastasis by Altering RNA Metabolism
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1101/2025.02.19.638943

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888214/
  123. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An RNA Splicing System that Excises Transposons from Animal mRNAs
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1101/2025.02.14.638102

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870413/
  124. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIP13 protects pancreatic cancer cells against intrinsic and therapy-induced DNA replication stress
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1093/narcan/zcaf009

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    pmc.ncbi.nlm.nih.gov/articles/PMC11923746/
  125. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lanatoside C activates the E3 ligase STUB1 to inhibit FOXP3 transcriptional activity and promote antitumor immunity
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1038/s44321-025-00200-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11904033/
  126. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1038/s44318-025-00366-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11914266/
  127. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive genomic dependency landscape of a human colon cancer organoid
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1038/s42003-025-07822-5

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    pmc.ncbi.nlm.nih.gov/articles/PMC11906589/
  128. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting USP8 causes synthetic lethality through degradation of FGFR2 in ARID1A-deficient ovarian clear cell carcinoma
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1038/s41698-025-00850-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11903656/
  129. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-wide atlas of human cell morphology
    1
    1. scibot 23 Mar 2025
      12260

      DOI: 10.1038/s41592-024-02537-7

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  130. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intrinsic electrical activity drives small-cell lung cancer progression
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  131. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumour-wide RNA splicing aberrations generate actionable public neoantigens
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  132. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Massively parallel characterization of transcriptional regulatory elements
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  133. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ubiquinol-mediated suppression of mitochondria-associated ferroptosis is a targetable function of lactate dehydrogenase B in cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11911438/
  134. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of stress granule formation is a vulnerability imposed by mutant p53
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  135. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A positive feedback loop between SMAD3 and PINK1 in regulation of mitophagy
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  136. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway
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  137. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ubiquitination of gasdermin D N-terminal domain directs its membrane translocation and pore formation during pyroptosis
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  138. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of the LKB1-AMPK-SLC7A11-GSH signaling pathway sensitizes NSCLC to albumin-bound paclitaxel via oxidative stress
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  139. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LncRNA APTR amplification serves as a potential glioma biomarker and promotes glioma progression via miR-6734-5p/ TCF7/LEF1 axis
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  140. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Crip2 affects vascular development by fine-tuning endothelial cell aggregation and proliferation
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  141. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Next Generation Aqueous Two‐Phase System for Gentle, Effective, and Timely Extracellular Vesicle Isolation and Transcriptomic Analysis
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  142. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor Cell‐Expressed Herpesvirus Entry Mediator Regulates Proliferation and Adaptive Immunity in Ovarian Cancer
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  143. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation
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      plasmid_12260

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  144. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced therapeutic efficacy of anti-PD-1 blockade by targeting LAMP2A inhibits lysosomal degradation of STING and TBK1
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      Addgene_12260

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  145. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies
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  146. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction
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  147. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Succinate dehydrogenase activity supports de novo purine synthesis
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  148. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic deprogramming by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers
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      plasmid_12260

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  149. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    POT, an optogenetics-based endogenous protein degradation system
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  150. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Crohn’s Disease-associated variant in laccase domain containing 1 (LACC1) modulates T cell gene expression, metabolism and T cell function
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  151. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition
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  152. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CPC-shelterin-BTR axis regulates mitotic telomere deprotection
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  153. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP7 V517F mutation as a mechanism of inhibitor resistance
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      plasmid_12260

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    pmc.ncbi.nlm.nih.gov/articles/PMC11909274/
  154. www.cell.com www.cell.com
    Small-molecule RNA therapeutics to target prostate cancer
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    cell.com/cancer-cell/fulltext/S1535-6108(25)00079-0
  155. www.sciencedirect.com www.sciencedirect.com
    Spatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin
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    sciencedirect.com/science/article/pii/S1097276525001479
  156. www.sciencedirect.com www.sciencedirect.com
    Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism
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  157. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microglia clonal inflammatory disorder in Alzheimer’s disease
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  158. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overlapping and distinct functions of SPT6, PNUTS, and PCF11 in regulating transcription termination
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  159. www.sciencedirect.com www.sciencedirect.com
    Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
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  160. www.sciencedirect.com www.sciencedirect.com
    Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors
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      AddgeneCat# 12260

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  161. www.sciencedirect.com www.sciencedirect.com
    Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
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  162. www.sciencedirect.com www.sciencedirect.com
    YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1-mediated reprogramming of bone mesenchymal stem cells
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  163. www.sciencedirect.com www.sciencedirect.com
    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
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  164. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The TCF4 Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy
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  165. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protein phosphatase EYA1 regulates the dephosphorylation and turnover of BCL2L12 to promote glioma development
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  166. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Association of Selected STAT Inhibitors with Prolactin-Induced Protein (PIP) in Breast Cancer
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  167. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATF3-SLC7A7 Axis Regulates mTORC1 Signaling to Suppress Lipogenesis and Tumorigenesis in Hepatocellular Carcinoma
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  168. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth
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  169. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sodium valproate enhances efficacy of NKG2D CAR-T cells against glioblastoma
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      psPAX2

      DOI: 10.3389/fimmu.2024.1519777

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  170. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Histone Demethylase LSD1/ZNF217/CoREST Complex is a Major Restriction Factor of Epstein-Barr Virus Lytic Reactivation
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      12260

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  171. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration
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      pSPAX2

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    pmc.ncbi.nlm.nih.gov/articles/PMC11884777/
  172. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    γ-secretase facilitates retromer-mediated retrograde transport
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1242/jcs.263538

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    pmc.ncbi.nlm.nih.gov/articles/PMC11883284/
  173. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glutathione peroxidase 4 (GPX4) and obesity interact to impact tumor progression and treatment response in triple negative breast cancer
    1
    1. scibot 11 Mar 2025
      psPAX2

      DOI: 10.1186/s40170-025-00380-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11863593/
  174. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1186/s12864-025-11386-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC11863645/
  175. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and characterization of a double-fluorescent HIV-1 reporter cellular model to tackle the Rev-dependent export pathway
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1128/spectrum.01903-24

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    pmc.ncbi.nlm.nih.gov/articles/PMC11878058/
  176. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Norovirus co-opts NINJ1 for selective protein secretion
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    1. scibot 11 Mar 2025
      12260

      DOI: 10.1126/sciadv.adu7985

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870086/
  177. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Local soft niches in mechanically heterogeneous primary tumors promote brain metastasis via mechanotransduction-mediated HDAC3 activity
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1126/sciadv.adq2881

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    pmc.ncbi.nlm.nih.gov/articles/PMC11864190/
  178. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CHIP protects lysosomes from CLN4 mutant-induced membrane damages
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.02.18.638932

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870535/
  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synergistic RAS-MAPK and AKT Activation in MYC-Driven Tumors via Adjacent PVT1 Rearrangements
    1
    1. scibot 11 Mar 2025
      psPAX2

      DOI: 10.1101/2025.02.17.638454

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870553/
  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optical Pooled Screening for the Discovery of Regulators of the Alternative Lengthening of Telomeres Pathway
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    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.02.15.638448

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    pmc.ncbi.nlm.nih.gov/articles/PMC11844499/
  181. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pyrimethamine and a potent analogue WCDD115 inhibit NRF2 by suppressing DHFR and one-carbon metabolism
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.02.13.637433

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870417/
  182. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EndoMAP.v1, a Structural Protein Complex Landscape of Human Endosomes
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.02.07.636106

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    pmc.ncbi.nlm.nih.gov/articles/PMC11839024/
  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel alpha-synuclein K58N missense variant in a patient with Parkinson’s disease
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    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.02.07.25321793

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    pmc.ncbi.nlm.nih.gov/articles/PMC11844588/
  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Higher throughput assays for understanding the pathogenicity of variants of unknown significance (VUS) in the RPE65 gene
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    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.01.31.635952

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    pmc.ncbi.nlm.nih.gov/articles/PMC11838478/
  185. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Haplotype rather than single causal variants effects contribute to regulatory gene expression associations in human myeloid cells
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.01.30.635675

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    pmc.ncbi.nlm.nih.gov/articles/PMC11838257/
  186. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular determinants of RNase MRP specificity and function
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    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.01.28.635360

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    pmc.ncbi.nlm.nih.gov/articles/PMC11838342/
  187. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.01.24.631210

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    pmc.ncbi.nlm.nih.gov/articles/PMC11785141/
  188. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.01.18.633717

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    pmc.ncbi.nlm.nih.gov/articles/PMC11785074/
  189. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Harnessing Extracellular Vesicles for Stabilized and Functional IL-10 Delivery in Macrophage Immunomodulation
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.01.14.633016

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    pmc.ncbi.nlm.nih.gov/articles/PMC11761701/
  190. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CellFIE: Integrating Pathway Discovery With Pooled Profiling of Perturbations Uncovers Pathways of Huntington’s Disease, Including Genetic Modifiers of Neuronal Development and Morphology
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2025.02.19.639023

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870572/
  191. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cardiolipin deficiency disrupts CoQ-complex III interface in steatohepatitis
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2024.10.10.617517

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    pmc.ncbi.nlm.nih.gov/articles/PMC11482932/
  192. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex, multimodal mapping of variant effects in secreted proteins
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2024.04.01.587474

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    pmc.ncbi.nlm.nih.gov/articles/PMC11838247/
  193. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional characterization of all CDKN2A missense variants and comparison to in silico models of pathogenicity
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2023.12.28.573507

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    pmc.ncbi.nlm.nih.gov/articles/PMC10793438/
  194. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trans-synaptic molecular context of NMDA receptor nanodomains
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1101/2023.12.22.573055

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    pmc.ncbi.nlm.nih.gov/articles/PMC10769418/
  195. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of triglyceride metabolism‐associated enhancers alters lipid deposition during adipocyte differentiation
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1096/fj.202401137R

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    pmc.ncbi.nlm.nih.gov/articles/PMC11774232/
  196. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1096/fj.202400490R

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    pmc.ncbi.nlm.nih.gov/articles/PMC11774231/
  197. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deletion of Xist repeat B disrupts cell cycle and asymmetric cell division through Usp9x hyperactivation in mice
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1093/nar/gkaf142

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    pmc.ncbi.nlm.nih.gov/articles/PMC11880805/
  198. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    c-JUN: a chromatin repressor that limits mesoderm differentiation in human pluripotent stem cells
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1093/nar/gkaf001

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    pmc.ncbi.nlm.nih.gov/articles/PMC11760979/
  199. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Harnessing transcriptional regulation of alternative end-joining to predict cancer treatment
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1093/narcan/zcaf007

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    pmc.ncbi.nlm.nih.gov/articles/PMC11886861/
  200. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC)
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1080/15592294.2025.2456418

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    pmc.ncbi.nlm.nih.gov/articles/PMC11776469/
  201. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors
    1
    1. scibot 11 Mar 2025
      12260

      DOI: 10.1038/s44319-024-00363-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11850905/