3,159 Matching Annotations
  1. Jul 2022
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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    sciencedirect.com/science/article/pii/S2211124722008324
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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    ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
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    Babesia microti Infection Inhibits Melanoma Growth by Activating Macrophages in Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9257138/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9259034/
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    Extracellular vesicles from thyroid cancer harbor a functional machinery involved in extracellular matrix remodeling
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    sciencedirect.com/science/article/pii/S0171933522000577
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    Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero
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    sciencedirect.com/science/article/pii/S193459092200251X
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    Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867422007231
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9252436/
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    An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates
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    sciencedirect.com/science/article/pii/S2667237522001138
  12. Jun 2022
  13. 52.53.155.43 52.53.155.43
    cd-21-1514-html.html
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    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
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    ncbi.nlm.nih.gov/pmc/articles/PMC9239677/
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    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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    sciencedirect.com/science/article/pii/S2211124722008087
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    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
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    embopress.org/doi/10.15252/embr.202154133
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    sciencedirect.com/science/article/pii/S109727652200541X
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    The cephalic phase of insulin release is modulated by IL-1β
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    sciencedirect.com/science/article/pii/S1550413122002212
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    Glypican-3 targeted thorium-227 alpha therapy reduces tumor burden in an orthotopic xenograft murine model of hepatocellular carcinoma
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    ROS Inhibits Cell Growth by Regulating 4EBP and S6K, Independent of TOR, during Development
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    ncbi.nlm.nih.gov/pmc/articles/PMC7612857/
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    Neoadjuvant FOLFIRINOX therapy is associated with increased effector T cells and reduced suppressor cells in pancreatic cancer patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC8678309/
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    GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
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    elifesciences.org/articles/64430
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    A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9197253/
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    Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1
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    sciencedirect.com/science/article/pii/S2589004222006241
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    Development of an HIV reporter virus that identifies latently infected CD4+ T cells
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    sciencedirect.com/science/article/pii/S2667237522001072
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    Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9167717/
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    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    sciencedirect.com/science/article/pii/S2589004222007520
  31. aacrjournals.org aacrjournals.org
    Phosphorylation and stabilization of PD-L1 by CK2 suppresses dendritic cell function
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    aacrjournals.org/cancerres/article/82/11/2185/699105/Phosphorylation-and-Stabilization-of-PD-L1-by-CK2
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    Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer
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    aacrjournals.org/mct/article/21/6/936/699192/Porcupine-Inhibition-Disrupts-Mitochondrial
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    Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo
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    sciencedirect.com/science/article/pii/S2666166722003215
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    BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen
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    sciencedirect.com/science/article/pii/S1074761322002230
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    Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model
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    sciencedirect.com/science/article/pii/S221112472200660X
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    Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits.
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    sciencedirect.com/science/article/pii/S0021925822005373
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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    sciencedirect.com/science/article/pii/S0960982222007783
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    Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer
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    link.springer.com/article/10.1186/s12967-022-03447-y
  39. May 2022
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binary outcomes of enhancer activity underlie stable random monoallelic expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9135403/
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    Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer
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    sciencedirect.com/science/article/pii/S2211124722006386
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    Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface
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    sciencedirect.com/science/article/pii/S2211124722006258
  43. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A human breast atlas integrating single-cell proteomics and transcriptomics
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    pubmed.ncbi.nlm.nih.gov/35617956/
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    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
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    sciencedirect.com/science/article/pii/S1534580722003069
  45. pubs.acs.org pubs.acs.org
    Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance
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    pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9122494/
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    The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis
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    sciencedirect.com/science/article/pii/S2211124722005411
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    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
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    elifesciences.org/articles/73998
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    Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody
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    sciencedirect.com/science/article/pii/S2666379122001604
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    Secretion of interleukin-1 by dedifferentiated melanoma cells inhibits JAK1-STAT3-driven actomyosin contractility of lymph node fibroblastic reticular cells
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    aacrjournals.org/cancerres/article/82/9/1774/694699/Secretion-of-IL1-by-Dedifferentiated-Melanoma
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    T cell transcription factor expression evolves over time in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques
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    sciencedirect.com/science/article/pii/S2211124722005976
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    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
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    sciencedirect.com/science/article/pii/S0092867422005268
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8595542/
  54. aacrjournals.org aacrjournals.org
    Genomic and single-cell landscape reveals novel drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphomaGenomic and single-cell landscape of transformed CTCL
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    aacrjournals.org/cancerdiscovery/article/12/5/1294/694564/Genomic-and-Single-Cell-Landscape-Reveals-Novel
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    EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma
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    aacrjournals.org/cancerdiscovery/article/12/5/1378/694560/EGFR-Inhibition-Potentiates-FGFR-Inhibitor-Therapy
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    Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength
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    Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model
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    sciencedirect.com/science/article/pii/S2666166722002441
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    Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation
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    link.springer.com/article/10.1007/s00109-022-02202-6
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone Marrow-Derived Stem Cell Factor Regulates Prostate Cancer-Induced Shifts in Pre-Metastatic Niche Composition
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    ncbi.nlm.nih.gov/pmc/articles/PMC9063312/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Augmentation of Extracellular ATP Synergizes With Chemotherapy in Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9065442/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC9064299/
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    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents
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    sciencedirect.com/science/article/pii/S2211124722005605
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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    sciencedirect.com/science/article/pii/S2211124722005551
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    PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms
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    sciencedirect.com/science/article/pii/S1934590922001588
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    Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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    sciencedirect.com/science/article/pii/S1550413122001358
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characteristics of immune memory and effector activity to cancer-expressed MHC class I phosphopeptides differ in healthy donors and ovarian cancer patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC8568670/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
  69. Apr 2022
  70. academic.oup.com academic.oup.com
    Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells
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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgac032/6556146
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    TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation
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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgac024/6540320
  72. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15838
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryopreserved PM21-Particle-Expanded Natural Killer Cells Maintain Cytotoxicity and Effector Functions In Vitro and In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9022621/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9035748/
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    Inflammation induces pro-NETotic neutrophils via TNFR2 signaling
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    sciencedirect.com/science/article/pii/S2211124722004715
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    Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection
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    sciencedirect.com/science/article/pii/S1931312822001585
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    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
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    sciencedirect.com/science/article/pii/S1097276522002684
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    ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
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    sciencedirect.com/science/article/pii/S2211124722004764
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    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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    sciencedirect.com/science/article/pii/S1534580722002295
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T-lymphopoiesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9010627/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
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    ncbi.nlm.nih.gov/pmc/articles/PMC9007588/
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    TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
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    sciencedirect.com/science/article/pii/S2211124722004090
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    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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    ncbi.nlm.nih.gov/pmc/articles/PMC8990213/
  84. www.nature.com www.nature.com
    TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence
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    nature.com/articles/s41417-022-00454-5
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    Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment
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    Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer
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    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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    sciencedirect.com/science/article/pii/S1074761322001297
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    Characterization of the secretome, transcriptome and proteome of human β cell line EndoC-βH1
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    sciencedirect.com/science/article/pii/S1535947622000378
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    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  179. www.sciencedirect.com www.sciencedirect.com
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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  181. Dec 2021
  182. elifesciences.org elifesciences.org
    IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25+Foxp3- T cells
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  183. www.sciencedirect.com www.sciencedirect.com
    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
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  184. crc.aacrjournals.org crc.aacrjournals.org
    The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance
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  185. mcr.aacrjournals.org mcr.aacrjournals.org
    Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases
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  186. www.sciencedirect.com www.sciencedirect.com
    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
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  188. elifesciences.org elifesciences.org
    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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  189. www.sciencedirect.com www.sciencedirect.com
    Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
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