3,159 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATOR-4066, a Bispecific Antibody Targeting CD40 and CEACAM5, Induces Strong Myeloid and T Cell–Dependent Tumor Immunity and Synergizes with PD-1 Blockade
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670079/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Priming with DNMT Inhibitors Potentiates PD-1 Immunotherapy by Triggering Viral Mimicry in Relapsed/Refractory NK/T-cell Lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670078/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133432/
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    TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12669767/
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    CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen
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    pmc.ncbi.nlm.nih.gov/articles/PMC12675586/
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    Eph receptors activate myeloid checkpoint receptor LILRB5 to support tumor development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137008/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Olaparib and radiotherapy induce type I interferon and CD8+ T cell-dependent sensitization to immunotherapy in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137021/
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    Targeting Interactions between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12671567/
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    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666321/
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    Blocking the TCA cycle in Cancer Cells Potentiates CD36+ T Cell-Mediated Antitumor Immunity by Suppressing ER Stress-Associated THBS2 Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129664/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti–PD-1 Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666320/
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    Jchain-Diphtheria Toxin Receptor Mice Allow for Depletion of Antibody-Secreting Cells and Analysis of Differentiation Kinetics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666722/
  14. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    OSCAR is an online ML-powered tool for organoid cell counting using bright-field images
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    sciencedirect.com:5037/science/article/pii/S2667237525002875
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    Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12664306/
  16. Nov 2025
  17. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    L-Phenylalanine is a metabolic checkpoint of human Th2 cells
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    sciencedirect.com:5037/science/article/pii/S2666379125005397
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    Combinatorial immunotherapy with agonistic CD40 activates dendritic cells to express IL12 and overcomes PD-1 resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12645833/
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    Enhanced anti-tumor efficacy of tumor-infiltrating lymphocytes by GITR agonist in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12631380/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autologous Thymic Organoids Support Functional T-cell Education and Enhance Antitumor Immunity in Humanized Mice with Melanoma Xenografts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12641387/
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    DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12642826/
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    Targeting CDK12/13 Drives Mitotic Arrest to Overcome Resistance to KRASG12C Inhibitors
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    Attenuating α-synuclein pathology in mice with in situ engineered astrocytes
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    link.springer.com/article/10.1186/s40035-025-00518-0
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    Lymphotoxin-driven cancer cell eradication by tumoricidal CD8+ TIL
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    biorxiv.org/content/10.1101/2025.11.19.689204v2
  25. 54.241.53.176 54.241.53.176
    jaeckstein-et-al-2025-purinergic-adipocyte-macrophage-crosstalk-promotes-degeneration-of-thermogenic-brown-adipose-html.html
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    Off-pore nucleoporin sPOM121 transcriptionally propels β-Catenin driven tumor progression and immune escape in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580793/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC and p53 Alterations Cooperate through VEGF Signaling to Repress Cytotoxic T Cell and Immunotherapy Responses in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12471896/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603150/
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    PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma
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    Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle arrest
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    embopress.org/doi/10.1038/s44321-025-00336-x
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    Integrin/CD44-targeted liposomes remodel the pulmonary microenvironment to alleviate acute exacerbation of pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S0168365925010417
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    IL-9 signaling redirects CAR T cell fate toward CD8+ memory and CD4+ cycling states, enhancing antitumor efficacy
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    sciencedirect.com/science/article/pii/S1074761325004753
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    Hybrid apoptotic body decorated supramolecular hydrogel system for melanoma cancer immunoediting
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    Alpinetin Nanoparticles Alleviate Optic Nerve Injury Induced by Acute Glaucoma via LRP1-PPARγ Mediated Regulation of Microglial Lipid Metabolism
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513270
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    Mechanisms of maternal antibody interference with rotavirus vaccination
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    Schlafen 12 Modulation and Targeting in Acute Myeloid Leukemia
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    An Fc-Engineered Glycomodified Antibody Supports Proinflammatory Activation of Immune Effector Cells and Restricts Progression of Breast Cancer
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    A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616247/
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    Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models
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    Modeling antithymocyte globulin-induced microvasculopathy using human iPSC-derived vascularized liver organoids
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    sciencedirect.com/science/article/pii/S2666379125005063
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    Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict
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    Mucosal viral infection elicits long-lived IgA responses via type 1 follicular helper T cells
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    A Balanced Cannabinoids Mixture Protects Neural Stem/progenitor Cells from CoCl2 Induced Injury by Regulating Autophagy and Inflammation: An in Vitro Study
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    Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs
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    Protocol for specific induction of apoptosis or necroptosis in established murine tumors
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    Loss of cyclin C drives resistance to anti-TIGIT therapy by upregulating CD155-mediated immune evasion
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    sciencedirect.com/science/article/pii/S1368764625001219
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    TAK1 is a key regulator of oncogenic signaling and differentiation blockade in rhabdomyosarcoma
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    biorxiv.org/content/10.1101/2025.11.03.686399v1
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591092/
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    Early alpha-synuclein accumulation, oxidative stress and inflammation in the proximal colon of c-rel−/− mouse model of Parkinson's disease
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    Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks
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    sciencedirect.com/science/article/pii/S1097276525008561
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    A novel mechanism by which c-MYC is aberrantly activated by epigenetic silencing of its antisense lncRNA in colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582551/
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    SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell–Mediated Cytotoxicity
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    Systematic Engineering of TROP2-Targeted CAR T-Cell Therapy Overcomes Resistance Pathways in Solid Tumors
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    Intracellular Interleukin-1α in Peritumoral Monocytes Induces IL8 Production and Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular Carcinoma
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    Use of a Foamy‐Virus Vector System to Produce an ‘Off‐the‐Shelf’ Fcγ‐CR‐T Cell Product for the Treatment of Haematological and Solid Tumour Malignancies
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    A novel strategy to target metabolic dependencies in acute myeloid leukemia
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    IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy
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    Global genome analysis identifies glycolipids and lipoteichoic acid alanylation as contributors to group B streptococcal diabetic wound infection
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    Targeting lncRNA MALAT1 attenuates lenalidomide resistance via CD38 epigenetic modulation, oxidative stress–mediated cell death, and remodeling of the pro-tumor microenvironment in multiple myeloma
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  62. Oct 2025
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    Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3
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    Combination of racotumomab immunotherapy with programmed death-1 blockade in a preclinical model of non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12541832/
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    Pan-cancer analysis of RNA expression signatures associated with cancer tissue architecture
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    Chronic Stress Disrupts Immune and Endocrine Axis, Inducing Persistent Behavioral Impairments in Male Rats: In Silico and In Vivo Insights
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    link.springer.com/article/10.1007/s11064-025-04579-5
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    Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis
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    CANDiT: A machine learning framework for differentiation therapy in colorectal cancer
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    Multi-parametric profiling of IL-7-augmented GD2.CART products in a phase 1 clinical trial
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    Quercetin Increases Expression of Membrane-TRAIL in Glioblastoma Cells Resulting in Apoptosis
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    Senataxin promotes recombination fidelity during antigen receptor gene diversification
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    Durability of DNA-LNP and mRNA-LNP Vaccine-Induced Immunity Against SARS-CoV-2 XBB.1.5
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    biorxiv.org/content/10.1101/2025.10.15.682549v1
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    eEF2K promotes immune evasion in melanoma via Cyclin D1–mediated stabilization of PD-L1
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    Decoding adult murine pancreatic islet cell diversity through cell type-resolved proteomics and phosphoproteomics
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    TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors
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    Specialized pro-resolving mediators MaR1 and LXA4 resolve inflammation during acute chemical lung injury in the absence of neutrophils
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    An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12502211/
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    Hypoxia Induces Immunosuppression by Silencing STING in Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12498107/
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    EZH2-driven immune evasion at disease presentation defines a targetable high-risk subset of acute leukemia exemplified by t(16;21) FUS::ERG AML
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    pmc.ncbi.nlm.nih.gov/articles/PMC11118270/
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    A novel Frizzled 7 antibody disrupts the Wnt pathway and inhibits Wilms tumor growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12504202/
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    YAP1 status defines two intrinsic subtypes of LCNEC with distinct molecular features and therapeutic vulnerabilities
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    Single Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T Cell Subpopulation that is Correlated with Response to Checkpoint Therapy in Melanoma
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  174. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  183. journals.asm.org journals.asm.org
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