3,086 Matching Annotations
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    TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors
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    sciencedirect.com/science/article/pii/S1535610825004039
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    Specialized pro-resolving mediators MaR1 and LXA4 resolve inflammation during acute chemical lung injury in the absence of neutrophils
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    sciencedirect.com/science/article/pii/S0002944025003773
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    An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12502211/
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    Hypoxia Induces Immunosuppression by Silencing STING in Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12498107/
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    EZH2-driven immune evasion at disease presentation defines a targetable high-risk subset of acute leukemia exemplified by t(16;21) FUS::ERG AML
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    pmc.ncbi.nlm.nih.gov/articles/PMC11118270/
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    A novel Frizzled 7 antibody disrupts the Wnt pathway and inhibits Wilms tumor growth
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    YAP1 status defines two intrinsic subtypes of LCNEC with distinct molecular features and therapeutic vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC11479841/
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    Single Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T Cell Subpopulation that is Correlated with Response to Checkpoint Therapy in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12356630/
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    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    Primate resident memory T cells activate humoral and stromal immunity
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    sciencedirect.com/science/article/pii/S1074761325004200
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    KRAS Inhibition Activates an Actionable CD24 “Don’t Eat Me” Signal in Pancreatic Cancer
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    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  15. Oct 2025
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    Integrated omics reveals disease-associated radial glia-like cells with epigenetically dysregulated interferon response in multiple sclerosis
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    sciencedirect.com/science/article/pii/S089662732500710X
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    BTN2A1 acquisition through trogocytosis enhances Vγ9Vδ2 T cell cytotoxicity against autologous and cancer cells
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    sciencedirect.com/science/article/pii/S2211124725011581
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    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
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    Chromosome-specific epigenetic control and transmission of ribosomal DNA arrays in Hominidae genomes
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    sciencedirect.com/science/article/pii/S2666979X25002873
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    Targeted citrullination enables p53 binding to non-canonical sites
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    The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells
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    Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK
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    Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner
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    nature.com/articles/s41467-025-63941-x
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    Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485599/
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    Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964848/
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053542/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depleting the Action of EZH2 through PI3K–mTOR Inhibition to Overcome Metastasis and Immunotherapy Resistance in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485387/
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    Increased Peripheral T Stem Cell–like Memory Features in Patients with Advanced Solid Tumors Treated with Tumor-Targeting IL-12 Immunocytokine Therapy
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma
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    Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiation Therapy
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  35. Sep 2025
  36. www.biorxiv.org www.biorxiv.org
    Chemotherapy Induces an IL1β-dependent Neutrophil Recruitment that Promotes Chemoresistance in Metastatic Ovarian Cancer
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    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    Inhibition of extracellular matrix protein fibulin-3 reduces immunosuppressive signaling and increases macrophage activation in glioblastoma
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    Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML
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    Requirements for establishment and epigenetic stability of mammalian heterochromatin
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    Tumor suppressor protein p53 governs human trophoblast lineage development
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    Extracellular vesicles of cancer cells induce FOXP3+ fibroblasts and facilitate tumor invasion via the Wnt3-β-catenin pathway
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    Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
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    LncRNA EUDAL shapes tumor cell response to hypoxia-induced constitutive EGFR activation and promotes chemoresistance in oral cancer
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    Development of a First-in-Class Click Chemistry–Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial
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    PPAR-δ Orchestrates a Pro-metastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402788/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12397289/
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    Targeting a pathogenic cryptic exon that drives HLRCC to induce exon skipping
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    pmc.ncbi.nlm.nih.gov/articles/PMC12396411/
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    Conserved LIR-specific interaction of Sigma-1 receptor and GABARAP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398221/
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    An HIV fusion-inhibitory lipopeptide provides robust post-exposure prophylaxis and prevents viral reservoir seeding in macaques
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    sciencedirect.com/science/article/pii/S2211124725009994
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    Bifidobacteria-derived exopolysaccharide promotes anti-tumor immunity
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    Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404271/
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    HuR-regulated extracellular vesicles promote endothelial cell remodeling in pancreatic cancer
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    Protocol for the coculture of murine vaginal epithelial organoids and T cells to induce resident memory CD8 T cell differentiation
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    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    science.org/doi/10.1126/sciadv.ady0240
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    AntimiR uptake by human proximal tubule epithelial cells is predominantly by macropinocytosis
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    nature.com/articles/s41598-025-16522-3
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    The antitumor effect of tlr4 inhibition in head and neck cancer cell lines
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    DCAF7 recruits USP2 to facilitate hepatocellular carcinoma progression by suppressing clockophagy-induced ferroptosis
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    nature.com/articles/s41419-025-07977-3
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    Immunodominant structural proteins Gc and N drive T cell-mediated protection against La Crosse virus
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  81. Aug 2025
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    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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    Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity
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    rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
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    TSG6 affects anti cancer drug resistance and angiogenesis in 3D spheroid model of canine mammary gland tumor cells
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    Therapy-Induced ECM Remodeling Creates a Transient Immune Barrier in Residual Melanoma
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    Spatial regulation of CD8+ T cells at the HLA-E-NKG2A axis drives HIV persistence in lymph node B cell follicles
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  172. www.cell.com www.cell.com
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  173. elifesciences.org elifesciences.org
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  174. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  175. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  176. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  177. aacrjournals.org aacrjournals.org
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  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  182. www.ahajournals.org www.ahajournals.org
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  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  185. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  186. link.springer.com link.springer.com
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  190. Jun 2025
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  195. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  196. www.sciencedirect.com www.sciencedirect.com
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  197. www.embopress.org www.embopress.org
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  202. www.tandfonline.com www.tandfonline.com
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  203. journals.physiology.org journals.physiology.org
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