3,014 Matching Annotations
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    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    science.org/doi/10.1126/sciadv.ady0240
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    AntimiR uptake by human proximal tubule epithelial cells is predominantly by macropinocytosis
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    nature.com/articles/s41598-025-16522-3
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    The antitumor effect of tlr4 inhibition in head and neck cancer cell lines
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    nature.com/articles/s41598-025-15927-4
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    DCAF7 recruits USP2 to facilitate hepatocellular carcinoma progression by suppressing clockophagy-induced ferroptosis
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    nature.com/articles/s41419-025-07977-3
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    Immunodominant structural proteins Gc and N drive T cell-mediated protection against La Crosse virus
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    sciencedirect.com/science/article/pii/S2589004225016396
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    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124725009702
  8. Aug 2025
  9. rupress.org rupress.org
    Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity
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    rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
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    TSG6 affects anti cancer drug resistance and angiogenesis in 3D spheroid model of canine mammary gland tumor cells
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    nature.com/articles/s41598-025-12950-3
  11. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Therapy-Induced ECM Remodeling Creates a Transient Immune Barrier in Residual Melanoma
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202508451
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    Cutaneous neuroanatomical and cellular response to dupilumab treatment in atopic dermatitis
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    sciencedirect.com/science/article/pii/S0022202X2502353X
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    Veillonella intestinal colonization promotes C. difficile infection in Crohn’s disease
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    sciencedirect.com/science/article/pii/S1931312825002914
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    Spatial regulation of CD8+ T cells at the HLA-E-NKG2A axis drives HIV persistence in lymph node B cell follicles
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    sciencedirect.com/science/article/pii/S2211124725009520
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    Exogenous estrogen enhances T cell activation in male primates
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    sciencedirect.com/science/article/pii/S2211124725009416
  16. www.biorxiv.org www.biorxiv.org
    Free fatty acid receptor 4 agonists stimulate insulin secretion via different mechanisms in mouse versus human islets
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    biorxiv.org/content/10.1101/2025.08.15.670586v1
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    Single-cell clonal lineage tracing identifies the transcriptional program controlling the cell fate decisions by neoantigen-specific CD8+ T cells
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    biorxiv.org/content/10.1101/2025.08.13.670223v1
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    Cyclin-dependent kinase 9 inhibitors as oncogene signaling modulators in combination with targeted therapy for the treatment of colorectal cancer
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    biorxiv.org/content/10.1101/2025.08.13.669992v1
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blocking NRF2 Translation by Inhibition of Cap-Dependent Initiation Sensitizes Lymphoma Cells to Ferroptosis and CAR T-cell Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363560/
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    Suppression of mTOR Signaling by miR-302/367 Cluster in Breast Cancer Cells
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202501582R
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lymphodepletion, tumor-infiltrating lymphocytes, and high versus low dose IL-2 followed by pembrolizumab in patients with metastatic melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12360205/
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    A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy
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    tandfonline.com/doi/full/10.1080/2162402X.2025.2543620
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    The absence of IL17A favours cytotoxic cell function and improves antigen-specific immunotherapies in pancreatic adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.70442
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    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
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    Lymphodepletion, tumor-infiltrating lymphocytes, and high versus low dose IL-2 followed by pembrolizumab in patients with metastatic melanoma
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    tandfonline.com/doi/full/10.1080/2162402X.2025.2546402
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    Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways
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    sciencedirect.com/science/article/pii/S2211124725009210
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12350263/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CircMORC1 downregulated in plasma EVs promotes gastric cancer cell proliferation and invasion via miR-103a-1-5p sponging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12344900/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12351279/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-Associated Modulation of TREM1/2-Expressing Macrophages Promotes Melanoma Progression and Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12352130/
  31. www.nature.com www.nature.com
    Inhibition of LDHB triggers DNA damage and increases cisplatin sensitivity in pleural mesothelioma
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    nature.com/articles/s41389-025-00571-4
  32. www.biorxiv.org www.biorxiv.org
    Human IRAK kinases differentially alter metabolic regulation and mitochondrial function in Saccharomyces cerevisiae
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    biorxiv.org/content/10.1101/2025.08.06.668917v1
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    Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation
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    sciencedirect.com/science/article/pii/S109727652500615X
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers | EMBO reports
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332006/
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    Mechanical signaling via β2 integrin decouples T cell proliferation and differentiation for generating stem cell-like CAR T cells
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    sciencedirect.com/science/article/pii/S1074761325003279
  36. journals.asm.org journals.asm.org
    Inhibition of efflux pumps by FDA-approved drugs oxiconazole and sertaconazole restores antibiotic susceptibility in multidrug-resistant S. aureus
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    journals.asm.org/doi/10.1128/aac.00320-25
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Neutrophil Storage Pool in the Fetal Liver is the Principal Source of the Postnatal Neutrophil Surge
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    pmc.ncbi.nlm.nih.gov/articles/PMC12326356/
  38. jitc.bmj.com jitc.bmj.com
    An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release
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    jitc.bmj.com/content/13/8/e011857
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    Highly conserved Betacoronavirus sequences are broadly recognized by human T cells
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    sciencedirect.com/science/article/pii/S0092867425008049
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319402/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316456/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790382/
  45. pubs.rsna.org pubs.rsna.org
    Perfluorobutane-enhanced US Targeting M2 Tumor-associated Macrophages for Predicting Programmed Cell Death-1 Response in Hepatocellular Carcinoma | Radiology: Imaging Cancer
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    pubs.rsna.org/doi/full/10.1148/rycan.240472
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314529/
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    Tumor cell-intrinsic Decr2 regulates ferroptosis and immunotherapy efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314507/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CTG-Initiated Cryptic Peptide Translation Up- and Downstream of a Canonical ATG Start Codon Is Enhanced by TLR Stimulation and Induces Tumor Regression in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314520/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
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    Characteristics of a CCL21 gene-modified dendritic cell vaccine utilized for a clinical trial in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11813162/
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    PMN recruitment in inflammatory lung injury models follows classical transendothelial migration paradigms requiring PECAM-1 and CD99
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    pmc.ncbi.nlm.nih.gov/articles/PMC12312685/
  52. pubs.rsna.org pubs.rsna.org
    Perfluorobutane-enhanced US Targeting M2 Tumor-associated Macrophages for Predicting Programmed Cell Death-1 Response in Hepatocellular Carcinoma
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    pubs.rsna.org/doi/10.1148/rycan.240472
  53. www.sciencedirect.com www.sciencedirect.com
    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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    sciencedirect.com/science/article/pii/S2211124725008137
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    Myeloid cell networks govern re-establishment of original immune landscapes in recurrent ovarian cancer
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    sciencedirect.com/science/article/pii/S1535610825002764
  55. Jul 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characterization of human CMV-specific CD8+ T cells using multi-layer single-cell omics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12296424/
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    Stathmin Serine 16 Phosphorylation Is a Key Regulator of Cell Cycle Progression Without Activating Migration and Invasion In Vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC12293763/
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    A human neuron alzheimer’s disease model reveals barriers to senolytic translatability
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    pmc.ncbi.nlm.nih.gov/articles/PMC12297865/
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    PLT012, a humanized CD36-blocking antibody, is effective for unleashing anti-tumor immunity against liver cancer and liver metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617665/
  60. 52.53.155.43 52.53.155.43
    Inhibition of glutaminase 1 activity reverses airway hyperresponsiveness and decreases IL-1β+ M1s and IL-17 producing ILC3s in high-fat diet-fed obese mice
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    52.53.155.43/4962c8654320fb21d270a9a33cb9a80f745af745/shim-et-al-2023-inhibition-of-glutaminase-1-activity-reverses-airway-hyperresponsiveness-and-decreases-il-1-m1s-and-il (1)-html.html
  61. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    biorxiv.org/content/10.1101/2025.07.21.665972v1
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    Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways
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    rupress.org/jcb/article/224/9/e202312133/278137/Ubiquitin-chain-variability-directs-substrates-of
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    Chimeric antigen receptor T cells in treatment-refractory DAGLA antibody-associated encephalitis
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    cell.com/med/abstract/S2666-6340(25)00203-X
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    Asynchronous aging and turnover of human circulating and tissue-resident memory T cells across sites
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    sciencedirect.com/science/article/pii/S1074761325003103
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    MyD88 polymerization and association to cellular membranes in a yeast heterologous model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12297185/
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    Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion
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    nature.com/articles/s41419-025-07863-y
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    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12277487/
  70. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  71. pubs.acs.org pubs.acs.org
    Novel Aptamer-Drug Conjugate for Targeted Therapy in Triple-Negative Breast Cancer
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c00492
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  73. journals.physiology.org journals.physiology.org
    Inhibition of glutaminase 1 activity reverses airway hyperresponsiveness and decreases IL-1β+ M1s and IL-17 producing ILC3s in high-fat diet-fed obese mice
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    journals.physiology.org/doi/10.1152/ajplung.00181.2022
  74. www.mdpi.com www.mdpi.com
    Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models
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    mdpi.com/2072-6694/17/14/2342
  75. www.nature.com www.nature.com
    Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids
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    nature.com/articles/s41467-025-61442-5
  76. 52.53.155.43 52.53.155.43
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  77. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tuning antibody stability and function by rational designs of framework mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12269682/
  80. www.cell.com www.cell.com
    SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress
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    cell.com/cell-reports/fulltext/S2211-1247(25)00710-7
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12267311/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260515/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoallelic mutations in MMD2 cause autosomal dominant aggressive periodontitis
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  84. 52.53.155.43 52.53.155.43
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    TAF1 is required for fetal but not adult hematopoiesis in mice
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