3,075 Matching Annotations
  1. Jun 2022
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    Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation
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    sciencedirect.com/science/article/pii/S2211124722007252
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    Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice
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    sciencedirect.com/science/article/pii/S2211124722007215
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    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
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    sciencedirect.com/science/article/pii/S2589004222007180
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    CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X
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    sciencedirect.com/science/article/pii/S221112472200626X
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    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    sciencedirect.com/science/article/pii/S109727652200483X
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    Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
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    sciencedirect.com/science/article/pii/S1550413122001863
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    PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine
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    sciencedirect.com/science/article/pii/S1534580722003495
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    A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
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    sciencedirect.com/science/article/pii/S2451945622001659
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    Active APPL1 sequestration by Plasmodium favors liver-stage development
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    sciencedirect.com/science/article/pii/S2211124722006611
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9141420/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC9147548/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
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    Patient-derived microphysiological model identifies the therapeutic potential of metformin for thoracic aortic aneurysm
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    sciencedirect.com/science/article/pii/S2352396422002614
  15. May 2022
  16. academic.oup.com academic.oup.com
    Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells
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    academic.oup.com/humrep/advance-article/doi/10.1093/humrep/deac112/6590738
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    The V2 receptor antagonist tolvaptan counteracts proliferation and invasivity in human cancer cells
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    link.springer.com/article/10.1007/s40618-022-01807-5
  18. pubs.acs.org pubs.acs.org
    Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance
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    pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  20. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7072571/'https://www.researchsquare.com/article/rs-7072571/v1
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    Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury
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    sciencedirect.com/science/article/pii/S2589004222006502
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    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004222006113
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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    sciencedirect.com/science/article/pii/S2211124722005952
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    Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation
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    sciencedirect.com/science/article/pii/S2211124722005897
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    A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika
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    sciencedirect.com/science/article/pii/S2211124722005873
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    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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    The Role of ATF3 in Neuronal Differentiation and Development of Neuronal Networks in Opossum Postnatal Cortical Cultures
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    ncbi.nlm.nih.gov/pmc/articles/PMC9100162/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAF V600E mutant human glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8595717/
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    Matricellular protein WISP2 is an endogenous inhibitor of collagen linearization and cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8595651/
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    Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia
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    sciencedirect.com/science/article/pii/S2211124722005587
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    Protocol to induce and assess cGAS-STING pathway activation in vitro
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    sciencedirect.com/science/article/pii/S2666166722002647
  32. aacrjournals.org aacrjournals.org
    Triple targeting of HER receptors overcomes heregulin-mediated resistance to EGFR blockade in colorectal cancer
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    aacrjournals.org/mct/article/21/5/799/694777/Triple-Targeting-of-HER-Receptors-Overcomes
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    Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor
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    sciencedirect.com/science/article/pii/S2211124722005356
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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    sciencedirect.com/science/article/pii/S2211124722005551
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    A text-based computational framework for patient -specific modeling for classification of cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC9076893/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function
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    ncbi.nlm.nih.gov/pmc/articles/PMC9083168/
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    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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    sciencedirect.com/science/article/pii/S1074761322001777
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Redox profiles of Amyotrophic Lateral Sclerosis lymphoblasts with or without known SOD1 mutations
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    onlinelibrary.wiley.com/doi/10.1111/eci.13798
  39. www.nature.com www.nature.com
    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
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    nature.com/articles/s41598-022-11116-9
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte
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    ncbi.nlm.nih.gov/pmc/articles/PMC9047870/
  41. Apr 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
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    ncbi.nlm.nih.gov/pmc/articles/PMC9038906/
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15849
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    Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice
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    sciencedirect.com/science/article/pii/S2589004222005119
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    Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice
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    sciencedirect.com/science/article/pii/S2666379122001239
  46. academic.oup.com academic.oup.com
    Deletion of Gdf15 reduces ER stress-induced beta cell apoptosis and diabetes
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    academic.oup.com/endo/article/163/5/bqac030/6548945
  47. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Distinct roles of glutamine metabolism in benign and malignant cartilage tumors with IDH mutations
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    asbmr.onlinelibrary.wiley.com/doi/10.1002/jbmr.4532
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular tau oligomers affect extracellular glutamate handling by astrocytes through downregulation of GLT-1 expression and impairment of NKA1A2 function
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    onlinelibrary.wiley.com/doi/10.1111/nan.12811
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    GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease
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    sciencedirect.com/science/article/pii/S1044743122000355
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    Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
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    sciencedirect.com/science/article/pii/S2352396422001694
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    Selective activation of ABCA1/ApoA1 signalling in the V1 by magnetoelectric stimulation ameliorates depression via regulation of synaptic plasticity
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    sciencedirect.com/science/article/pii/S2589004222004710
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    The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression
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    sciencedirect.com/science/article/pii/S2211124722004260
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9007586/
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    Rapid establishment of human colonic organoid knockout lines
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    SENP1-Sirt3 signaling promotes α-ketoglutarate production during M2 macrophage polarization
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    sciencedirect.com/science/article/pii/S2211124722004120
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    sciencedirect.com/science/article/pii/S2211124722003199
  57. www-sciencedirect-com.iclibezp1.cc.ic.ac.uk www-sciencedirect-com.iclibezp1.cc.ic.ac.uk
    Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer
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    Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy
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    sciencedirect.com/science/article/pii/S2211124722003862
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    A negative feedback loop of TOR signaling balances growth and stress-response trade-offs in plants
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    In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1
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    link.springer.com/article/10.1007/s11064-022-03570-8
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    Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
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    sciencedirect.com/science/article/pii/S1550413122000936
  62. journals.physiology.org journals.physiology.org
    Goblet cell hyperplasia is not epithelial-autonomous in the Cftr knockout intestine
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    journals.physiology.org/doi/full/10.1152/ajpgi.00290.2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dyslipidemia, insulin resistance, and impairment of placental metabolism in the offspring of obese mothers
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    ncbi.nlm.nih.gov/pmc/articles/PMC8606174/
  64. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Maintenance of glutamine synthetase expression alleviates endotoxin-induced sepsis via alpha-ketoglutarate-mediated demethylation
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202200059R
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8966496/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8959598/
  67. Mar 2022
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA-590-3P suppresses cell survival and triggers breast cancer cell apoptosis via targeting sirtuin-1 and deacetylation of p53
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    onlinelibrary.wiley.com/doi/10.1002/jcb.28211
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    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
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    sciencedirect.com/science/article/pii/S2352396422001347
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    Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development
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    onlinelibrary.wiley.com/doi/10.1002/dneu.22871
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    Cortical reorganization of the glutamate synapse in the activity-based anorexia rat model: impact on cognition
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15605
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Poly (ADP-ribose) polymerase 1-mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15606
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Toxicities of amyloid-beta and tau protein are reciprocally ... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC9083152/
  74. www.nature.com www.nature.com
    ADARs act as potent regulators of circular transcriptome in cancer
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    nature.com/articles/s41467-022-29138-2
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8938989/
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Interleukin-18mediated inflammatory brain injury after intracerebral hemorrhage in male mice
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    onlinelibrary.wiley.com/doi/10.1002/jnr.25044
  77. www.sciencedirect.com www.sciencedirect.com
    Comprehensive proteomic profiling of plasma and serum phosphatidylserine-positive extracellular vesicles reveals tissue-specific proteins
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    sciencedirect.com/science/article/pii/S2589004222002826
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    Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy
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    Protocol for RNA fluorescence in situ hybridization in mouse meningeal whole mounts
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    sciencedirect.com/science/article/pii/S2666166722001368
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    sciencedirect.com/science/article/pii/S266637912200060X
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    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    sciencedirect.com/science/article/pii/S2211124722002479
  83. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    sciencedirect.com/science/article/pii/S2211124722002066
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    Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments
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    sciencedirect.com/science/article/pii/S2211124722001358
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    Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response
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  87. academic.oup.com academic.oup.com
    Canonical thyroid hormone receptor β action stimulates hepatocyte proliferation in male mice
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    academic.oup.com/endo/article/163/3/bqac003/6509895
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant induction of a mesenchymal/stem-cell program engages senescence in normal mammary epithelial cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC8867383/
  89. elifesciences.org elifesciences.org
    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
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    elifesciences.org/articles/72917
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    Engineering of thick human functional myocardium via static stretching and electrical stimulation
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