2,232 Matching Annotations
  1. Jan 2020
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    The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria
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    Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State
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    Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease
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  8. Nov 2018
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    Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing
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    Molecular Interface of Neuronal Innate Immunity, Synaptic Vesicle Stabilization, and Presynaptic Homeostatic Plasticity
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    Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks
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    The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death
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    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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    Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes
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    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
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    A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression
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    The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands
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    Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma
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    Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase
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    Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency
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    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death
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    NonA and CPX Link the Circadian Clockwork to Locomotor Activity in Drosophila
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    BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor
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    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
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    Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex
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    Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
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    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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    Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2
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    Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain
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    Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
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    The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
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    Palladin Is a Neuron-Specific Translational Target of mTOR Signaling That Regulates Axon Morphogenesis
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    EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
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    Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria
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    GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion
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