2,383 Matching Annotations
  1. Feb 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles
    1
    1. scibot 24 Feb 2021
      RRID:Addgene # 12260

      DOI: 10.1016/j.celrep.2020.107652

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    sciencedirect.com/science/article/pii/S2211124720306057
  3. www.sciencedirect.com www.sciencedirect.com
    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
    1
    1. scibot 24 Feb 2021
      12260

      DOI: 10.1016/j.molcel.2020.12.040

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    sciencedirect.com/science/article/pii/S1097276520309618
  4. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
    1
    1. scibot 24 Feb 2021
      Addgene_12260

      DOI: 10.1016/j.celrep.2020.01.012

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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  5. www.nature.com www.nature.com
    On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1038/s41596-019-0248-1

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    nature.com/articles/s41596-019-0248-1
  6. www.jneurosci.org www.jneurosci.org
    Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development
    1
    1. scibot 24 Feb 2021
      plasmid_12

      DOI: 10.1523/JNEUROSCI.1707-19.2020

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    jneurosci.org/content/40/25/4824
  7. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 24 Feb 2021
      RRID:_Addgene_12260

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  8. www.cell.com www.cell.com
    Live Imaging Reveals Listeria Hijacking of E-Cadherin Recycling as It Crosses the Intestinal Barrier
    1
    1. scibot 24 Feb 2021
      Addgene_12260

      DOI: 10.1016/j.cub.2020.11.041

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    cell.com/current-biology/fulltext/S0960-9822(20)31753-X
  9. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  10. www.cell.com www.cell.com
    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
    1
    1. scibot 24 Feb 2021
      Plasmid_12260

      DOI: 10.1016/j.ccell.2020.11.005

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    cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.carbpol.2021.117797

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    ncbi.nlm.nih.gov/pmc/articles/PMC7882221/
  12. www.sciencedirect.com www.sciencedirect.com
    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2020.12.046

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    sciencedirect.com/science/article/pii/S1097276520309886
  13. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
    1
    1. scibot 19 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2021.01.030

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    sciencedirect.com/science/article/pii/S1097276521000502
  14. www.sciencedirect.com www.sciencedirect.com
    Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption
    1
    1. scibot 17 Feb 2021
      #12260

      DOI: 10.1016/j.cub.2021.01.028

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    sciencedirect.com/science/article/pii/S0960982221000610
  15. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation
    1
    1. scibot 13 Feb 2021
      plasmid_12260

      DOI: 10.1016/j.celrep.2020.02.010

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    sciencedirect.com/science/article/pii/S2211124720301649
  16. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site
    1
    1. scibot 11 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1158/2159-8290.CD-20-1092

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    cancerdiscovery.aacrjournals.org/content/11/2/340
  17. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype
    1
    1. scibot 11 Feb 2021
      Plasmid_12260

      DOI: 10.1016/j.celrep.2021.108726

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    sciencedirect.com/science/article/pii/S2211124721000395
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_12260

      DOI: 10.3389/fmicb.2020.613963

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    ncbi.nlm.nih.gov/pmc/articles/PMC7862720/
  19. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_12260

      DOI: 10.7554/eLife.60609

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    elifesciences.org/articles/60609
  20. www.sciencedirect.com www.sciencedirect.com
    Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2021.108703

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    sciencedirect.com/science/article/pii/S2211124721000164
  21. Jan 2021
  22. www.sciencedirect.com www.sciencedirect.com
    GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells
    1
    1. scibot 28 Jan 2021
      Addgene_12260

      DOI: 10.1016/j.stem.2020.03.005

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    sciencedirect.com/science/article/pii/S1934590920300977
  23. www.sciencedirect.com www.sciencedirect.com
    FOS licenses early events in stem cell activation driving skeletal muscle regeneration
    1
    1. scibot 27 Jan 2021
      Addgene_12260

      DOI: 10.1016/j.celrep.2020.108656

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      RRIDCUR:Validated RRID:Addgene_12260
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    sciencedirect.com/science/article/pii/S2211124720316454
  24. www.sciencedirect.com www.sciencedirect.com
    Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities
    1
    1. scibot 27 Jan 2021
      plasmid_12260

      DOI: 10.1016/j.celrep.2020.03.073

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    sciencedirect.com/science/article/pii/S2211124720303995
  25. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
    1. scibot 15 Jan 2021
      Plasmid_12260

      DOI: 10.1016/j.chom.2020.04.024

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      RRIDCUR:Validated RRID:Addgene_12260
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    sciencedirect.com/science/article/pii/S1931312820302511
  26. www.sciencedirect.com www.sciencedirect.com
    Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
    1
    1. scibot 15 Jan 2021
      Plasmid_12260

      DOI: 10.1016/j.celrep.2020.107731

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      RRIDCUR:Validated RRID:Addgene_12260
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    sciencedirect.com/science/article/pii/S2211124720307117
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
    1
    1. scibot 08 Jan 2021
      RRID:Addgene_12260

      DOI: 10.7554/eLife.58461

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    ncbi.nlm.nih.gov/pmc/articles/PMC7781600/
  28. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    1
    1. scibot 07 Jan 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2020.108532

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    sciencedirect.com/science/article/pii/S2211124720315217
  29. elifesciences.org elifesciences.org
    Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1
    1
    1. scibot 06 Jan 2021
      RRID:Addgene_12260

      DOI: 10.7554/eLife.58037

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    elifesciences.org/articles/58037
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways
    1
    1. scibot 05 Jan 2021
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2020.108541

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    ncbi.nlm.nih.gov/pmc/articles/PMC7901356/
  31. Dec 2020
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes
    1
    1. scibot 25 Dec 2020
      RRID:Addgene_12260

      DOI: 10.1128/IAI.00017-20

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    ncbi.nlm.nih.gov/pmc/articles/PMC7309616/
  33. www.sciencedirect.com www.sciencedirect.com
    FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
    1
    1. scibot 24 Dec 2020
      psPAX2

      DOI: 10.1016/j.cub.2020.11.052

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      RRIDCUR:Missing RRID:Addgene_12260
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    sciencedirect.com/science/article/pii/S0960982220317656
  34. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
    1
    1. scibot 17 Dec 2020
      psPAX2

      DOI: 10.1016/j.celrep.2020.108493

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    sciencedirect.com/science/article/pii/S2211124720314820
  35. www.sciencedirect.com www.sciencedirect.com
    Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids
    1
    1. scibot 13 Dec 2020
      Plasmid_12260

      DOI: 10.1016/j.cels.2020.11.002

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    sciencedirect.com/science/article/pii/S2405471220304208
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration
    1
    1. scibot 10 Dec 2020
      RRID:Addgene_12260

      DOI: 10.7554/eLife.61552

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    ncbi.nlm.nih.gov/pmc/articles/PMC7685702/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Assessment of Efficacy and Safety Analysis of CAR-T Cells (ISIKOK-19) Targeting CD19-Expressing B-Cells for the First Turkish Academic Clinical Trial with Relapsed/Refractory ALL and NHL Patients
    1
    1. scibot 09 Dec 2020
      RRID:Addgene_12260

      DOI: 10.4274/tjh.galenos.2020.2020.0070

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    ncbi.nlm.nih.gov/pmc/articles/PMC7702660/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library
    1
    1. scibot 07 Dec 2020
      Addgene_12260

      DOI: 10.1186/s12915-020-00905-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7686728/
  39. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
    1
    1. scibot 07 Dec 2020
      Plasmid_12260

      DOI: 10.1016/j.immuni.2020.11.015

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    pubmed.ncbi.nlm.nih.gov/33275896/
  40. Nov 2020
  41. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors
    1
    1. scibot 25 Nov 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2020.108395

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    pubmed.ncbi.nlm.nih.gov/33207205/
  42. www.nature.com www.nature.com
    Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells
    1
    1. scibot 24 Nov 2020
      psPAX2

      DOI: 10.1038/s41419-020-03159-5

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    nature.com/articles/s41419-020-03159-5
  43. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
    1
    1. scibot 12 Nov 2020
      psPAX2

      DOI: 10.1016/j.celrep.2020.108341

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    sciencedirect.com/science/article/pii/S2211124720313309
  44. www.nature.com www.nature.com
    Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein
    1
    1. scibot 12 Nov 2020
      RRID:Addgene_12260

      DOI: 10.1038/s41598-020-76135-w

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    nature.com/articles/s41598-020-76135-w
  45. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
    1
    1. scibot 05 Nov 2020
      psPAX2

      DOI: 10.1016/j.cell.2020.10.028

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  46. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
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  47. Oct 2020
  48. www.sciencedirect.com www.sciencedirect.com
    IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
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    Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells
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    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
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  51. elifesciences.org elifesciences.org
    Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity
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  52. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
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  53. www.embopress.org www.embopress.org
    Identification of a dynamic gene regulatory network required for pluripotency factor‐induced reprogramming of mouse fibroblasts and hepatocytes
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  54. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer
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  55. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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    MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
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      psPAX2 plasmid

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  57. Sep 2020
  58. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Single point mutations within the Coxsackie B virus receptor-binding site promote resistance against soluble virus receptor traps
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    m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity
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    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
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  63. www.sciencedirect.com www.sciencedirect.com
    A drug screening toolkit based on the –1 ribosomal frameshifting of SARS-CoV-2
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  64. www.sciencedirect.com www.sciencedirect.com
    RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling
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    Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria
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  66. academic.oup.com academic.oup.com
    Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway
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      DOI: 10.1093/carcin/bgaa072

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgaa072/5867997
  67. www.sciencedirect.com www.sciencedirect.com
    Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
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  68. www.nature.com www.nature.com
    High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements
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  70. www.sciencedirect.com www.sciencedirect.com
    Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo
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  71. rupress.org rupress.org
    GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508
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      RRID:Addgene_12260

      DOI: 10.1083/jcb.201811014

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  72. www.sciencedirect.com www.sciencedirect.com
    Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
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  73. elifesciences.org elifesciences.org
    Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease
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    An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput, Temporal and Dose Dependent, Effect of Vitamins and Minerals on Chondrogenesis
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP regulates cell size and growth dynamics via non-cell autonomous mediators
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  77. doi.org doi.org
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  78. www.sciencedirect.com www.sciencedirect.com
    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
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    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay
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    A universal reporter cell line for bioactivity evaluation of engineered cytokine products
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction
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    SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro
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  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of the catalytic subunit of DNA‐dependent protein kinase (DNA‐PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses
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    Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
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    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis
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      DOI: 10.1016/j.chembiol.2020.04.003

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  88. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
    2
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells
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  92. www.sciencedirect.com www.sciencedirect.com
    YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways
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  93. www.sciencedirect.com www.sciencedirect.com
    Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
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    An Optimized Protocol for Human Direct Cardiac Reprogramming
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  95. link.springer.com link.springer.com
    A Modified Lentivirus-Based Reporter for Magnetic Separation of Cancer Stem Cells
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms
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  97. journals.plos.org journals.plos.org
    Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles
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  98. www.sciencedirect.com www.sciencedirect.com
    Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis
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    Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells
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  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
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  102. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
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  103. bioone.org bioone.org
    Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy
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    bioone.org/journals/radiation-research/volume-193/issue-4/RADE-20-00013/Endogenous-Retrovirus-Activation-as-a-Key-Mechanism-of-Anti-Tumor/10.1667/RADE-20-00013.full
  104. elifesciences.org elifesciences.org
    Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK signalling regulates antioxidant responses in neurons
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  106. academic.oup.com academic.oup.com
    Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling
    1
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      psPAX2

      DOI: 10.1210/en.2018-00290

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  107. www.sciencedirect.com www.sciencedirect.com
    RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha
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      Addgene Cat #12260

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  108. www.jbc.org www.jbc.org
    Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification
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  109. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
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  110. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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  111. www.nature.com www.nature.com
    Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
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  112. www.sciencedirect.com www.sciencedirect.com
    FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells
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  113. www.sciencedirect.com www.sciencedirect.com
    Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer
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  114. www.sciencedirect.com www.sciencedirect.com
    Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac
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  115. www.sciencedirect.com www.sciencedirect.com
    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
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  116. www.sciencedirect.com www.sciencedirect.com
    Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit
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  117. www.sciencedirect.com www.sciencedirect.com
    The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation
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  118. www.sciencedirect.com www.sciencedirect.com
    MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
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    PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development
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    A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance
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  121. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
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  122. pubs.acs.org pubs.acs.org
    Proximal Biotinylation Based Combinatory Approach for Isolating Integral Plasma Membrane Proteins
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      RRID: Addgene_12260

      DOI: 10.1021/acs.jproteome.0c00113

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  123. www.sciencedirect.com www.sciencedirect.com
    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
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      psPAX2

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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins
    1
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      Addgene plasmid 12260

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  125. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion
    1
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      psPAX

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  126. www.jbc.org www.jbc.org
    ABC transporters control ATP release through cholesterol-dependent volume-regulated anion channel activity
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      Addgene plasmid 12260

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  127. www.jbc.org www.jbc.org
    The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex
    1
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      Addgene_12260

      DOI: 10.1074/jbc.RA120.012820

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    jbc.org/content/295/28/9281.full
  128. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  129. Aug 2020
  130. www.sciencedirect.com www.sciencedirect.com
    A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV
    1
    1. scibot 31 Aug 2020
      Addgene plasmid #12260

      DOI: 10.1016/j.celrep.2019.12.054

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    sciencedirect.com/science/article/pii/S2211124719317115
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
    1
    1. scibot 22 Aug 2020
      RRID: Addgene_12260

      DOI: 10.3389/fncel.2020.00151

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    ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
  132. Jan 2020
  133. www.nature.com www.nature.com
    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
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    1. scibot 13 Jan 2020
      Addgene_12260

      DOI: 10.1038/s41467-019-13086-5

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    nature.com/articles/s41467-019-13086-5
  134. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.cub.2019.09.041

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    sciencedirect.com/science/article/pii/S0960982219312321
  135. www.sciencedirect.com www.sciencedirect.com
    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.07.086

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    sciencedirect.com/science/article/pii/S2211124719310022
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells
    1
    1. scibot 13 Jan 2020
      plasmid_12260

      DOI: 10.1186/s40170-019-0205-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC6937848/
  137. www.sciencedirect.com www.sciencedirect.com
    Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.06.084

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    sciencedirect.com/science/article/pii/S2211124719308642
  138. www.nature.com www.nature.com
    A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1038/s41556-019-0408-0

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    nature.com/articles/s41556-019-0408-0
  139. www.sciencedirect.com www.sciencedirect.com
    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2019.05.030

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    sciencedirect.com/science/article/pii/S1097276519304022
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.7554/eLife.50087

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    ncbi.nlm.nih.gov/pmc/articles/PMC6890464/
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.7554/eLife.47498

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    ncbi.nlm.nih.gov/pmc/articles/PMC6739868/
  142. link.springer.com link.springer.com
    Essential thrombocytosis attributed to <Emphasis Type="Italic">JAK2</Emphasis>-T875N germline mutation
    1
    1. scibot 13 Jan 2020
      plasmid_12260

      DOI: 10.1007/s12185-019-02725-8

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    link.springer.com/article/10.1007/s12185-019-02725-8
  143. www.sciencedirect.com www.sciencedirect.com
    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.devcel.2019.11.012

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    sciencedirect.com/science/article/pii/S1534580719309438
  144. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2019.06.007

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    sciencedirect.com/science/article/pii/S1535610819302983
  145. www.sciencedirect.com www.sciencedirect.com
    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.08.105

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    sciencedirect.com/science/article/pii/S2211124719311672
  146. www.sciencedirect.com www.sciencedirect.com
    Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.07.014

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    sciencedirect.com/science/article/pii/S2211124719309040
  147. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2019.10.011

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    sciencedirect.com/science/article/pii/S1535610819304854
  148. www.sciencedirect.com www.sciencedirect.com
    Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.ebiom.2019.08.074

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    sciencedirect.com/science/article/pii/S2352396419305961
  149. www.sciencedirect.com www.sciencedirect.com
    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2019.10.044

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    sciencedirect.com/science/article/pii/S0092867419312218
  150. www.nature.com www.nature.com
    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
    1
    1. scibot 13 Jan 2020
      plasmid_12260

      DOI: 10.1038/s41421-019-0110-1

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    nature.com/articles/s41421-019-0110-1
  151. www.sciencedirect.com www.sciencedirect.com
    Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.11.047

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    sciencedirect.com/science/article/pii/S2211124719315293
  152. www.sciencedirect.com www.sciencedirect.com
    Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2019.11.007

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    sciencedirect.com/science/article/pii/S1097276519308366
  153. www.sciencedirect.com www.sciencedirect.com
    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2019.06.005

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    sciencedirect.com/science/article/pii/S0092867419306336
  154. www.nature.com www.nature.com
    MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
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    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1038/s41467-019-11568-0

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    nature.com/articles/s41467-019-11568-0
  155. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1158/0008-5472.CAN-18-2156

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    cancerres.aacrjournals.org/content/79/10/2511
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1371/journal.ppat.1008037

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    ncbi.nlm.nih.gov/pmc/articles/PMC6855412/
  157. www.sciencedirect.com www.sciencedirect.com
    Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2019.06.020

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    sciencedirect.com/science/article/pii/S1097276519304769
  158. elifesciences.org elifesciences.org
    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
    1
    1. scibot 13 Jan 2020
      Plasmid_12260

      DOI: 10.7554/eLife.47327

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    elifesciences.org/articles/47327
  159. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2019.05.013

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    sciencedirect.com/science/article/pii/S1535610819302557
  160. www.sciencedirect.com www.sciencedirect.com
    Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.09.066

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    sciencedirect.com/science/article/pii/S221112471931263X
  161. www.sciencedirect.com www.sciencedirect.com
    Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.08.102

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    sciencedirect.com/science/article/pii/S2211124719311647
  162. link.springer.com link.springer.com
    Evaluation of reference genes for quantitative real-time PCR in Wharton’s Jelly-derived mesenchymal stem cells after lentiviral transduction and differentiation
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1007/s11033-019-05207-6

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    link.springer.com/article/10.1007/s11033-019-05207-6
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stimulation of Piezo1 by mechanical signals promotes bone anabolism
    1
    1. scibot 13 Jan 2020
      plasmid_12260

      DOI: 10.7554/eLife.49631

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    ncbi.nlm.nih.gov/pmc/articles/PMC6779475/
  164. www.sciencedirect.com www.sciencedirect.com
    MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2019.09.011

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  165. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2019.01.018

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    sciencedirect.com/science/article/pii/S1535610819300522
  166. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      Plasmid_12260

      DOI: 10.1016/j.celrep.2018.12.100

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    sciencedirect.com/science/article/pii/S2211124718320758
  167. www.sciencedirect.com www.sciencedirect.com
    Widespread and Functional RNA Circularization in Localized Prostate Cancer
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      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2019.01.025

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  168. www.sciencedirect.com www.sciencedirect.com
    Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection
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      RRID:Addgene_12260

      DOI: 10.1016/j.cell.2019.04.036

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    sciencedirect.com/science/article/pii/S0092867419304556
  169. www.sciencedirect.com www.sciencedirect.com
    Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling
    1
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      RRID:Addgene_12260

      DOI: 10.1016/j.cmet.2019.03.005

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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.7554/eLife.39578

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    ncbi.nlm.nih.gov/pmc/articles/PMC6426440/
  171. www.sciencedirect.com www.sciencedirect.com
    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
    1
    1. scibot 13 Jan 2020
      Addgene_12260

      DOI: 10.1016/j.molcel.2018.06.041

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    sciencedirect.com/science/article/pii/S1097276518305161
  172. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      Addgene_12260

      DOI: 10.1016/j.cub.2018.08.060

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      RRID:Addgene_12260 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0960982218311448
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 13 Jan 2020
      Addgene_12260

      DOI: 10.1016/j.celrep.2019.03.063

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      RRID:Addgene_12260 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6499400/
  174. www.nature.com www.nature.com
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    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1038/s41388-019-0711-z

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      RRID:Addgene_12260 RRIDCUR:Validated
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    nature.com/articles/s41388-019-0711-z
  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Design and construction of a recombinant lentiviral vector with specific tropism to human epidermal growth factor‐overexpressed cancer cells: developing a new retargeting system for lentivirus vectors
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    1. scibot 13 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1002/jgm.3095

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    onlinelibrary.wiley.com/doi/full/10.1002/jgm.3095
  176. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
    1
    1. scibot 13 Jan 2020
      plasmid_12260

      DOI: 10.1016/j.cell.2018.05.009

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    sciencedirect.com/science/article/pii/S0092867418305865
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      plasmid_12260

      DOI: 10.1186/s40425-019-0575-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC6463631/
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      Addgene_12260

      DOI: 10.1016/j.immuni.2018.01.014

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    ncbi.nlm.nih.gov/pmc/articles/PMC6251713/
  179. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance
    1
    1. scibot 12 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2019.02.023

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    sciencedirect.com/science/article/pii/S2211124719301937
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation
    1
    1. scibot 12 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1523/ENEURO.0495-18.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6412672/
  181. www.sciencedirect.com www.sciencedirect.com
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      Plasmid_12260

      DOI: 10.1016/j.celrep.2018.09.071

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    sciencedirect.com/science/article/pii/S2211124718315316
  182. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:Addgene_12260

      DOI: 10.1111/bph.14563

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14563
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:Addgene_12260

      DOI: 10.1038/s41598-018-37940-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC6362041/
  184. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      plasmid_12260

      DOI: 10.1016/j.stem.2018.12.002

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    sciencedirect.com/science/article/pii/S1934590918305927
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 12 Jan 2020
      RRID:Addgene_12260

      DOI: 10.7554/eLife.43511

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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  186. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      RRID:Addgene_12260

      DOI: 10.1016/j.stem.2019.02.006

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    sciencedirect.com/science/article/pii/S1934590919300487
  187. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      Addgene_12260

      DOI: 10.1016/j.immuni.2018.11.013

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    sciencedirect.com/science/article/pii/S1074761318304953