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3,016 Matching Annotations

Jun 2021
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Bacterial genotoxins induce T cell senescence

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1. scibot 09 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109220
  
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sciencedirect.com/science/article/pii/S2211124721005714
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A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection

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1. scibot 04 Jun 2021
  
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  DOI: 10.7554/eLife.65762
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8163503/
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Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration

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1. scibot 02 Jun 2021
  
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  DOI: 10.3389/fphar.2021.679741
  
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frontiersin.org/article/10.3389/fphar.2021.679741/full
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Type I interferon decreases macrophage energy metabolism during mycobacterial infection

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1. scibot 02 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109195
  
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sciencedirect.com/science/article/pii/S2211124721005416
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Transcription factor Ascl2 promotes germinal center B cell responses by directly regulating AID transcription

1
1. scibot 02 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109188
  
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sciencedirect.com/science/article/pii/S2211124721005349
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BPS Publications

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1. scibot 01 Jun 2021
  
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  DOI: 10.1111/bph.15373
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15373
May 2021
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Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets

1
1. scibot 26 May 2021
  
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  DOI: 10.1016/j.immuni.2021.05.001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8101792/
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Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells

1
1. scibot 26 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109167
  
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sciencedirect.com/science/article/pii/S221112472100509X
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Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis

1
1. scibot 26 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109168
  
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sciencedirect.com/science/article/pii/S2211124721005106
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Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

1
1. scibot 21 May 2021
  
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  DOI: 10.7554/eLife.65777
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8131104/
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BPS Publications

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1. scibot 20 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15413
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15413
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BPS Publications

1
1. scibot 20 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15435
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15435
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Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation

1
1. scibot 19 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109141
  
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sciencedirect.com/science/article/pii/S2211124721004800
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T cell self-reactivity during thymic development dictates the timing of positive selection

1
1. scibot 19 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.65435
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8116051/
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β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles

1
1. scibot 19 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.celrep.2021.109139
  
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sciencedirect.com/science/article/pii/S2211124721004782
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Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential

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1. scibot 18 May 2021
  
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  DOI: 10.1016/j.immuni.2021.04.014
  
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sciencedirect.com/science/article/pii/S107476132100176X
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In vitro co-culture of human intestinal organoids and lamina propria-derived CD4+ T cells

1
1. scibot 15 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.xpro.2021.100519
  
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sciencedirect.com/science/article/pii/S2666166721002264
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Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population

1
1. scibot 14 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.65412
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8110305/
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Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing

1
1. scibot 14 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.xpro.2021.100538
  
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sciencedirect.com/science/article/pii/S2666166721002458
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Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells

1
1. scibot 13 May 2021
  
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  DOI: 10.7554/eLife.66155
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8102063/
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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

1
1. scibot 12 May 2021
  
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  DOI: 10.1016/j.immuni.2021.04.019
  
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sciencedirect.com/science/article/pii/S1074761321001813
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Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

1
1. scibot 12 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109105
  
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sciencedirect.com/science/article/pii/S2211124721004393
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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

1
1. scibot 11 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.ccell.2021.03.004
  
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sciencedirect.com/science/article/pii/S1535610821001628
mcr.aacrjournals.org mcr.aacrjournals.org

Metabolic regulator IAPP (Amylin) is required for BRAF and RAS oncogene-induced senescence

1
1. scibot 10 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1158/1541-7786.MCR-20-0879
  
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mcr.aacrjournals.org/content/19/5/874
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Inflammation mediates the development of aggressive breast cancer following radiotherapy

1
1. scibot 10 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1158/1078-0432.CCR-20-3215
  
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clincancerres.aacrjournals.org/content/27/6/1778
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Radiotherapy delivered before CDK4/6 inhibitors mediates superior therapeutic effects in ER+ breast cancer

1
1. scibot 10 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1158/1078-0432.CCR-20-3871
  
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clincancerres.aacrjournals.org/content/27/7/1855
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [64Cu]Cu-NOTA-anti-CD8-Positron Emission Tomography

1
1. scibot 10 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1158/1078-0432.CCR-20-3243
  
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clincancerres.aacrjournals.org/content/27/7/1958
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A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

1
1. scibot 10 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1158/0008-5472.CAN-20-3510
  
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aacrjournals.org/cancerres/article/81/9/2358/670580/A-MyD88-IL1R-Axis-Regulates-PD-1-Expression-on
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 10 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15457
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15457
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BPS Publications

1
1. scibot 09 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15423
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15423
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Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation

1
1. scibot 09 May 2021
  
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  SCR_008520
  
  DOI: 10.1016/j.stem.2021.01.006
  
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sciencedirect.com/science/article/pii/S1934590921000060
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Multimerization of Zika Virus-NS5 Causes Ciliopathy and Forces Premature Neurogenesis

1
1. scibot 09 May 2021
  
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  SCR_008520
  
  DOI: 10.1016/j.stem.2020.10.002
  
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sciencedirect.com/science/article/pii/S1934590920304963
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Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.10.016
  
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sciencedirect.com/science/article/pii/S1934590920305105
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Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.stem.2020.07.003
  
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sciencedirect.com/science/article/pii/S1934590920303416
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Modulation of neuropathology and cognitive deficits by lipopolysaccharide preconditioning in a mouse pilocarpine model of status epilepticus

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1. scibot 08 May 2021
  
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  DOI: 10.1016/j.neuropharm.2020.108227
  
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sciencedirect.com/science/article/pii/S0028390820302951
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ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

1
1. scibot 08 May 2021
  
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  SCR_008520
  
  DOI: 10.1016/j.molcel.2021.03.001
  
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Methodological considerations for the enrichment of bone marrow endothelial and mesenchymal stromal cells

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Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus

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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

1
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Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues

1
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Production of the Cytokine VEGF-A by CD4+ T and Myeloid Cells Disrupts the Corneal Nerve Landscape and Promotes Herpes Stromal Keratitis

1
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Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

1
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A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver

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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis

1
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Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

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Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver

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HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis

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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

2
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  DOI: 10.1007/s00018-021-03818-6
  
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Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport

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Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses

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Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis

1
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  DOI: 10.1016/j.chom.2020.10.003
  
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Targeted Depletion of Bacteria from Mixed Populations by Programmable Adhesion with Antagonistic Competitor Cells

1
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HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins

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Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190

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Follicular regulatory T cells produce neuritin to regulate B cells

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Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

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MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

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Co-option of Neutrophil Fates by Tissue Environments

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Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells

1
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  DOI: 10.1016/j.cell.2021.01.018
  
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Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages

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Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells

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  DOI: 10.1016/j.cell.2020.06.037
  
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Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics

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Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy

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Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis

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Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer

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Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts

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  DOI: 10.1016/j.xcrm.2021.100254
  
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High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

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Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

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Immunogenomic Landscape of Hematological Malignancies

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Targeting obesity-induced macrophages during preneoplastic growth promotes mammary epithelial stem/progenitor activity, DNA damage and tumor formation

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  DOI: 10.1158/0008-5472.CAN-20-0789
  
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SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

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Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4+ T cells

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  DOI: 10.7554/eLife.63810
  
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Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases

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Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth

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  DOI: 10.7554/eLife.62648
  
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Astragaloside IV prevents Aβ1-42 oligomers-induced memory impairment and hippocampal cell apoptosis by promoting PPARγ/BDNF signaling pathway

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Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes

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A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus

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The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design

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Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance

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  DOI: 10.3390/cancers13071648
  
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Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging

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Capturing human trophoblast development with naive pluripotent stem cells in vitro

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SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

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  DOI: 10.1016/j.cell.2021.03.027
  
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Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation

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Cell population analysis of the adult murine subependymal neurogenic lineage by flow cytometry

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  DOI: 10.1016/j.xpro.2021.100425
  
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The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

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  DOI: 10.1016/j.chom.2021.03.001
  
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Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication

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  DOI: 10.1016/j.molcel.2021.03.003
  
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Mar 2021
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Enriching neural stem cell and anti‐inflammatory glial phenotypes with electrical stimulation after traumatic brain injury in male rats

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1. scibot 30 Mar 2021
  
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  DOI: 10.1002/jnr.24834
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24834
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The PI3K∂-Selective Inhibitor Idelalisib Induces T- and NK-Cell Dysfunction Independently of B-Cell Malignancy-Associated Immunosuppression

1
1. scibot 29 Mar 2021
  
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  DOI: 10.3389/fimmu.2021.608625
  
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frontiersin.org/articles/10.3389/fimmu.2021.608625/full
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H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model

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  DOI: 10.1016/j.ccell.2021.01.005
  
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Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

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  DOI: 10.1016/j.cell.2021.03.013
  
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Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery

1
1. scibot 21 Mar 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7960510/
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Protocol for high-throughput compound screening using flow cytometry in THP-1 cells

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  DOI: 10.1016/j.xpro.2021.100400
  
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Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells

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  DOI: 10.1016/j.xpro.2021.100389
  
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Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy

1
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  DOI: 10.1016/j.celrep.2021.108857
  
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KDM6B-dependent chromatin remodeling underpins effective virus-specific CD8+ T cell differentiation

1
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  DOI: 10.1016/j.celrep.2021.108839
  
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Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis

1
1. scibot 17 Mar 2021
  
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  DOI: 10.3390/cancers13051005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7957630/
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A SNP within the gene locus of the oxysterol receptor EBI2 is associated with EBI2 expression on blood lymphocytes in patients with IBD

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  DOI: 10.1111/bph.15395
  
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BPS Publications

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1. scibot 13 Mar 2021
  
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  DOI: 10.1111/bph.15357
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15357
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Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections

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  DOI: 10.1182/bloodadvances.2020002949
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7948268/
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Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination

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The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell–derived lung progenitors in 3D

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  DOI: 10.1038/s41596-020-00476-z
  
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy

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  DOI: 10.1007/s00262-021-02895-7
  
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In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse

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  DOI: 10.1016/j.xpro.2021.100361
  
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Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack

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  DOI: 10.1016/j.xcrm.2021.100209
  
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BPS Publications

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1. scibot 03 Mar 2021
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15385
  
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BPS Publications

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Human primed ILCPs support endothelial activation through NF-κB signaling

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A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia

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Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth

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Impact of Excipients on Stability of Polymer Microparticles for Autoimmune Therapy

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The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

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A Booster Dose Enhances Immunogenicity of the COVID-19 Vaccine Candidate ChAdOx1 nCoV-19 in Aged Mice

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Human adipose‐derived stromal/stem cells are distinct from dermal fibroblasts as evaluated by biological characterization and RNA sequencing

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CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes

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Detecting Tumor Antigen-Specific T Cells via Interaction-Dependent Fucosyl-Biotinylation

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The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

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Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses

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RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development

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Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

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Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

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Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain

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Integration of IL-2 and IL-4 signals coordinates divergent regulatory T cell responses and drives therapeutic efficacy

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Analysis of epicardial genes in embryonic mouse hearts with flow cytometry

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Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

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The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching

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Mice carrying an analogous heterozygous Dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy

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Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes

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Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones

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Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E

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The kinase PDK1 is critical for promoting T follicular helper cell differentiation

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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

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SARS-CoV-2 epitopes are recognized by a public and diverse repertoire of human T cell receptors

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Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge

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Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis

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Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies

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Transcriptional Diversity and Niche-Specific Distribution of Leukocyte Populations during Staphylococcus aureus Craniotomy-Associated Biofilm Infection

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The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure

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TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression

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Cone-shaped HIV-1 capsids are transported through intact nuclear pores

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The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma

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Isolation of human ESC-derived cardiac derivatives and embryonic heart cells for population and single-cell RNA-seq analysis

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Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

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Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

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Stem cell transplantation rescued a primary open-angle glaucoma mouse model

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Cardiolipin-mediated PPARγ S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia

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Plasma cell dynamics in the bone marrow niche

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Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

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Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

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RON Expression Mediates Lipopolysaccharide-Mediated Dendritic Cell Maturation via March-I

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Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

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Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells

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Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients

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Aspergillus fumigatus tryptophan metabolic route differently affects host immunity

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Isolation of tumor-resident CD8+ T cells from human lung tumors

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Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

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RNA binding RING E3-ligase DZIP3/hRUL138 stabilizes Cyclin D1 to drive cell cycle and cancer progression

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Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging

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Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells

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MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

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Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest

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Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

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Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection

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QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis

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Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing

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B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS

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Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

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Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment

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Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

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HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound

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Celiac Vagus Nerve Stimulation Recapitulates Angiotensin II-Induced Splenic Noradrenergic Activation, Driving Egress of CD8 Effector Cells

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Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis

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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

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The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

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Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates

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  DOI: 10.1016/j.cell.2020.09.063
  
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cell.com/cell/abstract/S0092-8674(20)31304-0
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Identification of tumor‐associated macrophage subsets that are associated with breast cancer prognosis

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1. scibot 11 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1002/ctm2.239
  
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GD2 or HER2 targeting T cell engaging bispecific antibodies to treat osteosarcoma

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1. scibot 11 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1186/s13045-020-01012-y
  
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Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

1
1. scibot 10 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.cell.2020.11.007
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7654323/
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BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages

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1. scibot 09 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.56309
  
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elifesciences.org/articles/56309
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Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends

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1. scibot 09 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.61302
  
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RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

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1. scibot 09 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.63452
  
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High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies

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1. scibot 07 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.ebiom.2020.103131
  
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Multiple Alternative Promoters and Alternative Splicing Enable Universal Transcription-Based Logic Computation in Mammalian Cells

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1. scibot 07 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.celrep.2020.108437
  
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Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo

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1. scibot 07 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1007/s00262-020-02780-9
  
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link.springer.com/article/10.1007/s00262-020-02780-9
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BPS Publications

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1. scibot 07 Dec 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15216
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15216
Nov 2020
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MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression

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1. scibot 26 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.55676
  
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JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

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1. scibot 25 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.celrep.2020.108407
  
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Calciprotein particle-induced cytotoxicity via lysosomal dysfunction and altered cholesterol distribution in renal epithelial HK-2 cells

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1. scibot 24 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1038/s41598-020-77308-3
  
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nature.com/articles/s41598-020-77308-3
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The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress

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1. scibot 21 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.58020
  
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Isolation of Human CD49f+ Astrocytes and In Vitro iPSC-Based Neurotoxicity Assays

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1. scibot 15 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.xpro.2020.100172
  
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Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction

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1. scibot 12 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.57920
  
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Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling

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  DOI: 10.1016/j.celrep.2020.108333
  
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Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures

1
1. scibot 07 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1016/j.celrep.2020.108346
  
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Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation

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  DOI: 10.1016/j.celrep.2020.108331
  
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BPS Publications

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1. scibot 05 Nov 2020
  
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  RRID:SCR_008520
  
  DOI: 10.1111/bph.15237
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7589013/
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Critical role of WNK1 in MYC-dependent early mouse thymocyte development

1
1. scibot 31 Oct 2020
  
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  RRID:SCR_008520
  
  DOI: 10.7554/eLife.56934
  
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TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity

1
1. scibot 31 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108326
  
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sciencedirect.com/science/article/pii/S2211124720313152

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