3,420 Matching Annotations
  1. Oct 2023
  2. www.sciencedirect.com www.sciencedirect.com
    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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    sciencedirect.com/science/article/pii/S1097276523007505
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased degradation of FMRP contributes to neuronal hyperexcitability in tuberous sclerosis complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10529098/
  4. www.cell.com www.cell.com
    Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses
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    cell.com/immunity/abstract/S1074-7613(23)00367-9
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    TET3 plays a critical role in white adipose development and diet-induced remodeling
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    sciencedirect.com/science/article/pii/S2211124723012081
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimizing Bioink Composition for Human Chondrocyte Expression of Lubricin
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    ncbi.nlm.nih.gov/pmc/articles/PMC10526043/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9-Mediated CtBP1 Gene Editing Enhances Chemosensitivity and Inhibits Metastatic Potential in Esophageal Squamous Cell Carcinoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10530806/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Early Neoplasia Index (ENI10), Based on Molecular Identity of CD10 Cells and Associated Stemness Biomarkers, is a Predictor of Patient Outcome in Many Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10540743/
  9. Sep 2023
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    Essential role of the amino-terminal region of Drosha for the Microprocessor function
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    sciencedirect.com/science/article/pii/S2589004223020485
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    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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    sciencedirect.com/science/article/pii/S0925443923002624
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    Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner
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    sciencedirect.com/science/article/pii/S2211124723011695
  13. www.biorxiv.org www.biorxiv.org
    Discovering chromatin dysregulation induced by protein-coding perturbations at scale
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    biorxiv.org/content/10.1101/2023.09.20.555752v1
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    Differential Modulation of Polycomb-Associated Histone Marks by cBAF, pBAF, and gBAF Complexes
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    biorxiv.org/content/10.1101/2023.09.23.557848v2
  15. journals.asm.org journals.asm.org
    Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB
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    journals.asm.org/doi/10.1128/mbio.01857-23
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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    ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
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    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
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    sciencedirect.com/science/article/pii/S1934590923002461
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential nanoscale organization of excitatory synapses onto excitatory vs inhibitory neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10508768/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAP1 promotes osteoclast function by metabolic reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516877/
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Alterations of lipid-mediated mitophagy result in aging-dependent sensorimotor defects
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    onlinelibrary.wiley.com/doi/10.1111/acel.13954
  21. 52.53.155.43 52.53.155.43
    vdad120-html.html
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  22. www.nature.com www.nature.com
    HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling
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    nature.com/articles/s41419-023-05549-x
  23. www.nature.com www.nature.com
    MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression
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    nature.com/articles/s41698-023-00437-1
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    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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    sciencedirect.com/science/article/pii/S2211124723010951
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    A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification
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    biorxiv.org/content/10.1101/2023.09.12.557406v1
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    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
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    sciencedirect.com/science/article/pii/S2211124723011099
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    m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency
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    nature.com/articles/s41556-023-01212-x
  28. link.springer.com link.springer.com
    Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization
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    link.springer.com/article/10.1007/s13402-023-00867-w
  29. www.biorxiv.org www.biorxiv.org
    TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling
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    biorxiv.org/content/10.1101/2023.09.04.556165v1
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10470315/
  31. link.springer.com link.springer.com
    The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain
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    link.springer.com/article/10.1007/s11481-023-10082-x
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    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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    sciencedirect.com/science/article/pii/S2211124723010811
  33. Aug 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
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    sciencedirect.com/science/article/pii/S2666979X23002136
  35. www.biorxiv.org www.biorxiv.org
    Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins
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    biorxiv.org/content/10.1101/2023.08.18.553740v1
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cas phosphorylation regulates focal adhesion assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC10435235/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10437005/
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    Novel fourth generation-like CARmiR cells release therapeutic miRNA via exosomes and enhance glioblastoma cell killing activity
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    sciencedirect.com/science/article/abs/pii/S1369703X23002632
  39. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
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    nature.com/articles/s41596-023-00863-2
  40. www.nature.com www.nature.com
    TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
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    nature.com/articles/s41467-023-40755-3
  41. 52.53.155.43 52.53.155.43
    Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses
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  42. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
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    Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling
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    biorxiv.org/content/10.1101/2023.08.08.552533v1
  44. 52.53.155.43 52.53.155.43
    2023.08.14.553170v1.full-html.html
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  45. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
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    sciencedirect.com/science/article/pii/S1097276523005671
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    Conserved use of the sodium/bile acid cotransporter (NTCP) as an entry receptor by hepatitis B virus and domestic cat hepadnavirus
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    sciencedirect.com/science/article/pii/S0166354223001730
  48. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10423075/
  50. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
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    52.53.155.43/9f1a09025b86686c62561e67323b0c82e4153e7b/PIIS2666379123002987-html.html
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    TIM3 is a context-dependent co-regulator of cytotoxic T cell function
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    biorxiv.org/content/10.1101/2023.08.03.551797v1
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    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
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    52.53.155.43/e4339d2342058d0ba733e06b854674a1d2f752a1/PIIS2211124723009725-html.html
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    Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder
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    ncbi.nlm.nih.gov/pmc/articles/PMC10405067/
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    mcr-22-0916-html.html
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    Mapping the dynamic high-density lipoprotein synapse
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    sciencedirect.com/science/article/pii/S0021915023051079
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    sciencedirect.com/science/article/pii/S2211124723009385
  57. www.embopress.org www.embopress.org
    The cell cycle protein MAD2 facilitates endocytosis of the serotonin transporter in the neuronal soma
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    embopress.org/doi/10.15252/embr.202153408
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10370032/
  59. Jul 2023
  60. www.nature.com www.nature.com
    Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
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    nature.com/articles/s41594-023-01041-4
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10372429/
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    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  63. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    sciencedirect.com/science/article/pii/S1534580723003313
  64. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coding and non-coding elements comprise a regulatory network controlling transcription in Kaposi’s sarcoma-associated herpesvirus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10350069/
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    A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling
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    sciencedirect.com/science/article/pii/S2211124723008306
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    Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
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    sciencedirect.com/science/article/pii/S2211124723008057
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    52.53.155.43/bc0eed2683790c341dcd40acf534b132d1de8ed2/2023.05.10.540298.full-html.html
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    Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer
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    onlinelibrary.wiley.com/doi/10.1002/advs.202301088
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin nucleators safeguard replication forks by limiting nascent strand degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10325910/
  71. pubs.acs.org pubs.acs.org
    SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy
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    pubs.acs.org/doi/10.1021/acsnano.3c01916
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    Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons
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    sciencedirect.com/science/article/pii/S2589004223011215
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    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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    nature.com/articles/s41420-023-01526-7
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    TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
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    sciencedirect.com/science/article/pii/S0092867423006451
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    Cell-based assay to determine Type 3 Secretion System translocon assembly in Pseudomonas aeruginosa using split luciferase
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    biorxiv.org/content/10.1101/2023.06.22.546099v1
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    Oncogenic K-Ras suppresses global miRNA function
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    sciencedirect.com/science/article/pii/S109727652300429X
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    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
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    sciencedirect.com/science/article/pii/S2211124723007362
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    Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways
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    sciencedirect.com/science/article/pii/S2211124723007167
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  82. Jun 2023
  83. www.sciencedirect.com www.sciencedirect.com
    Identification of XAF1 as an endogenous AKT inhibitor
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    sciencedirect.com/science/article/pii/S2211124723007015
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    Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
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    sciencedirect.com/science/article/pii/S2211124723006915
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    sciencedirect.com/science/article/pii/S0092867423005986
  86. www.sciencedirect.com www.sciencedirect.com
    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S2589004223011926
  87. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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    nature.com/articles/s41417-023-00637-8
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10274806/
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    Development of a Series of Neutralizing Nanobodies against SARS-CoV-2 Spike Protein
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    link.springer.com/article/10.1134/S0026893323030196
  90. www.biorxiv.org www.biorxiv.org
    A functional single nucleotide polymorphism upstream of the collagen type III gene may contribute to catastrophic fracture risk in Thoroughbred horses
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