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Jan 2024
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Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control

1
1. scibot 30 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.1038/s41419-024-06423-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10803372/
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Loss of postsynaptic NMDARs drives nanoscale reorganization of Munc13-1 and PSD-95

1
1. scibot 30 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1101/2024.01.12.574705
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802569/
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Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability

1
1. scibot 29 Jan 2024
  
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  #12260; Addgene
  
  DOI: 10.3390/cells13020199
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10814814/
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Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation

1
1. scibot 29 Jan 2024
  
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  Addgene, Watertown, MA, USA, catalog 12260
  
  DOI: 10.3390/v16010116
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10819576/
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Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles

1
1. scibot 29 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.1016/j.bioactmat.2023.12.027
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10821609/
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HPV16 E6 Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway

1
1. scibot 29 Jan 2024
  
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  Addgene_12260
  
  DOI: 10.3390/v16010113
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10819893/
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Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia

1
1. scibot 29 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1007/s00018-023-05095-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10817852/
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D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability

1
1. scibot 29 Jan 2024
  
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  Plasmid_12260
  
  DOI: 10.1101/2024.01.12.575420
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802603/
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Hepatitis C virus E1 recruits high-density lipoprotein to support infectivity and evade antibody recognition

1
1. scibot 28 Jan 2024
  
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  psPAX2 plasmid (Addgene)
  
  DOI: 10.1128/jvi.00849-23
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10804985/
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N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modiﬁcation of the lymphocyte antigen six family member E (LY6E) mRNA

1
1. scibot 28 Jan 2024
  
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  PsPAX2
  
  DOI: 10.1128/jvi.01350-23
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10805074/
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SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids

1
1. scibot 28 Jan 2024
  
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  psPAX2
  
  DOI: 10.3389/fcell.2023.1268226
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10806012/
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Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier physiology in Friedreich’s ataxia

1
1. scibot 28 Jan 2024
  
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  12,260
  
  DOI: 10.3389/fmolb.2023.1299201
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10808331/
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A Novel Anti-CD47 Nanobody Tetramer for Cancer Therapy

1
1. scibot 28 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.3390/antib13010002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10801496/
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Abscisic acid signaling through LANCL2 and PPARγ induces activation of p38MAPK resulting in dormancy of prostate cancer metastatic cells

1
1. scibot 28 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.3892/or.2024.8698
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10804438/
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TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth

1
1. scibot 26 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.1016/j.jbc.2023.104713
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10200990/
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Cell-type-directed design of synthetic enhancers

1
1. scibot 25 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1038/s41586-023-06936-2
  
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nature.com/articles/s41586-023-06936-2
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Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus

1
1. scibot 20 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1128/mbio.02444-23
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10790771/
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Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

1
1. scibot 19 Jan 2024
  
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  Plasmid_12260
  
  DOI: 10.1016/j.celrep.2024.113678
  
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sciencedirect.com/science/article/pii/S2211124724000068
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SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13

1
1. scibot 19 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.cellsig.2024.111060
  
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sciencedirect.com/science/article/pii/S0898656824000287
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A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation

1
1. scibot 19 Jan 2024
  
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  RRID:Addgene_12
  
  DOI: 10.1016/j.canlet.2024.216635
  
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  Curator: @evieth
  
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  RRIDCUR:Unresolved RRID:Addgene_12260
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sciencedirect.com/science/article/pii/S0304383524000296
link.springer.com link.springer.com

Generation and optimization of off-the-shelf immunotherapeutics targeting TCR-Vβ2+ T cell malignancy

1
1. scibot 18 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1038/s41467-024-44786-2
  
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link.springer.com/article/10.1038/s41467-024-44786-2
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TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet

1
1. scibot 18 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2024.113673
  
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sciencedirect.com/science/article/pii/S2211124724000019
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment

1
1. scibot 13 Jan 2024
  
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  Addgene_12260
  
  DOI: 10.1016/j.ccell.2023.12.010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10783802/
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SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation

1
1. scibot 12 Jan 2024
  
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  Addgene_12260
  
  DOI: 10.1042/BSR20231418
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance

1
1. scibot 12 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.1158/2767-9764.CRC-23-0298
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10702273/
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Direct translation of incoming retroviral genomes

1
1. scibot 12 Jan 2024
  
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  Addgene_12260
  
  DOI: 10.1038/s41467-023-44501-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770327/
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Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins

1
1. scibot 11 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.113627
  
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sciencedirect.com/science/article/pii/S2211124723016388
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Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors

1
1. scibot 11 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.113629
  
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sciencedirect.com/science/article/pii/S2211124723016406
52.53.155.43 52.53.155.43

JNEUROSCI.2324-22.2023.full-html.html

1
1. scibot 11 Jan 2024
  
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  Addgene_12260
  
  DOI: 10.1523/jneurosci.2324-22.2023
  
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52.53.155.43/e3800d3a01c4a2c48734bb4b10f425b6dda51575/JNEUROSCI.2324-22.2023.full-html.html
www.sciencedirect.com www.sciencedirect.com

Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate

1
1. scibot 11 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.molcel.2023.12.007
  
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sciencedirect.com/science/article/pii/S1097276523010262
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Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus

1
1. scibot 11 Jan 2024
  
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  Addgene_12260
  
  DOI: 10.1016/j.cell.2023.11.031
  
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sciencedirect.com/science/article/pii/S0092867423013181
dx.doi.org dx.doi.org

Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome

1
1. scibot 10 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1093/nar/gkad1224
  
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dx.doi.org/10.1093/nar/gkad1224
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Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells

1
1. scibot 07 Jan 2024
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.113615
  
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sciencedirect.com/science/article/pii/S2211124723016273
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Direct effects of adipocyte lipolysis on AMPK through intracellular long-chain acyl-CoA signaling

1
1. scibot 06 Jan 2024
  
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  Addgene #12260
  
  DOI: 10.1038/s41598-023-50903-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10761689/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma

1
1. scibot 05 Jan 2024
  
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  Addgene#12260
  
  DOI: 10.1080/10985549.2023.2256640
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10761179/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FEBS Press

1
1. scibot 05 Jan 2024
  
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  plasmid_12260
  
  DOI: 10.1002/2211-5463.13741
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10761937/
Dec 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation

1
1. scibot 29 Dec 2023
  
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  RRID:Addgene_12260
  
  DOI: 10.1002/advs.202305620
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202305620
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Comparative Analysis of Cyclization Techniques in Stapled Peptides: Structural Insights into Protein–Protein Interactions in a SARS-CoV-2 Spike RBD/hACE2 Model System

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Human inherited CCR2 deficiency underlies progressive polycystic lung disease

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FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe

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Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis

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Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function

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High-throughput PRIME-editing screens identify functional DNA variants in the human genome

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The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent

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Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality

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Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

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Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics

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Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting

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B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling

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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

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978-1-0716-3593-3-html.html

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Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

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Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

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Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus

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RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis

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Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes

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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability

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Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines

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A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation

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Downstream STING pathways IRF3 and NF-κB differentially regulate CCL22 in response to cytosolic dsDNA

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Ammonia inhibits antitumor activity of NK cells by decreasing mature perforin

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ccr-22-3952-html.html

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Unraveling the Mechanisms of Sensitivity to Anti-FGF Therapies in Imatinib-Resistant Gastrointestinal Stromal Tumors (GIST) Lacking Secondary KIT Mutations

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SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression

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Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma

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The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection

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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

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PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer

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Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation

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Selective inhibition of CDK9 in triple negative breast cancer

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Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1

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Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53

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Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells

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Kaposi’s sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB

1
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Transcriptional reprogramming by mutated IRF4 in lymphoma

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Head and neck cancer stem cell maintenance relies on mTOR signaling, specifically involving the mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2)

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Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

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Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria

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Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species

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Vimentin intermediate filaments provide structural stability to the mammalian Golgi complex

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In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target

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In vitro formation and extended culture of highly metabolically active and contractile tissues

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Global identification of SWI/SNF targets reveals compensation by EP400

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ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers

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Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers

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Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells

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m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation

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Efficient exon skipping by base-editor-mediated abrogation of exonic splicing enhancers

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Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation

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Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling

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Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells

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Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level

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FEBS Press

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52.53.155.43/081c581c43e0c0f25916aa7621bfda2e34b6f467/Molecular Oncology - 2023 - Everest-Dass - Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis -html.html
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Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination

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Regulation of STING activity in DNA sensing by ISG15 modification

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Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus

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Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction

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Generation of a new Adar1p150−/− mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis

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Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein (RNP) to inhibit herpes simplex virus1 infection in vitro and in vivo

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Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells

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In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA

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Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8

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The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2

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Evaluation of potential targets to enhance the sensitivity of cholangiocarcinoma cells to anticancer drugs

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Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness

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DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C

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Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

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TET3 plays a critical role in white adipose development and diet-induced remodeling

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Increased degradation of FMRP contributes to neuronal hyperexcitability in tuberous sclerosis complex

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Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses

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TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells

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Optimizing Bioink Composition for Human Chondrocyte Expression of Lubricin

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CRISPR/Cas9-Mediated CtBP1 Gene Editing Enhances Chemosensitivity and Inhibits Metastatic Potential in Esophageal Squamous Cell Carcinoma Cells

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Pyruvate Kinase Activity Regulates Cystine Starvation Induced Ferroptosis through Malic Enzyme 1 in Pancreatic Cancer Cells

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Essential role of the amino-terminal region of Drosha for the Microprocessor function

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Differential Modulation of Polycomb-Associated Histone Marks by cBAF, pBAF, and gBAF Complexes

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TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice

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Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB

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Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells

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Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

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TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

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Differential nanoscale organization of excitatory synapses onto excitatory vs inhibitory neurons

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BAP1 promotes osteoclast function by metabolic reprogramming

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Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing

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vdad120-html.html

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PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer

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microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes

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HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling

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Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer

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CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

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Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

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m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency

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Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization

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Development of a V5-tag–directed nanobody and its implementation as an intracellular biosensor of GPCR signaling

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C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress

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TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

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IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner

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SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression

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Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons

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Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors

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4-Octyl itaconate restricts STING activation by blocking its palmitoylation

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Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells

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An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver

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TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation

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Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor

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Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses

3
1. scibot 19 Aug 2023
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.112925
  
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L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab

2
1. scibot 18 Aug 2023
  
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52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
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Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling

1
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Pharmacological perturbation of the phase-separating protein SMNDC1

1
1. scibot 17 Aug 2023
  
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  plasmid_12260
  
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A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis

2
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  plasmid_12260
  
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Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

2
1. scibot 17 Aug 2023
  
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  plasmid_12260
  
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2023.08.10.552871v1.full-html.html

1
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2023.08.14.553170v1.full-html.html

1
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing

1
1. scibot 16 Aug 2023
  
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  RRID: Addgene_12260
  
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METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy

1
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Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

1
1. scibot 16 Aug 2023
  
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Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development

1
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  RRID:Addgene_12260
  
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Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder

1
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  RRID:Addgene_12260
  
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52.53.155.43 52.53.155.43

mcr-22-0916-html.html

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  DOI: 10.1158/1541-7786.MCR-22-0916
  
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer

1
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  RRID:Addgene_12260
  
  DOI: 10.1158/2326-6066.CIR-22-0644
  
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Mapping the dynamic high-density lipoprotein synapse

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  addgene:12260
  
  DOI: 10.1016/j.atherosclerosis.2023.117200
  
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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

1
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The cell cycle protein MAD2 facilitates endocytosis of the serotonin transporter in the neuronal soma

1
1. scibot 03 Aug 2023
  
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  RRID:Addgene_12260
  
  DOI: 10.15252/embr.202153408
  
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Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

1
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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities

1
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Ketolysis drives CD8+ T cell effector function through effects on histone acetylation

1
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Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells

1
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  RRID:Addgene_12260
  
  DOI: 10.15252/embr.202256279
  
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Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy

1
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  Addgene_12260
  
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Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy

1
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Deep mutational scanning of whole SARS-CoV-2 spike in an inverted infection system

1
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  addgene_12260
  
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A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling

1
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.112819
  
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Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells

1
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  RRID:Addgene_12260
  
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52.53.155.43 52.53.155.43

Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal

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  12260
  
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52.53.155.43/8add9715cb6d409825df8305aa589d745e83436f/2023.05.03.539283.full-html.html
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Neuronal Activation of the Gαq Protein EGL-30/GNAQ Late in Life Rejuvenates Cognition Across Species

1
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer

1
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  RRID:Addgene_12
  
  DOI: 10.1002/advs.202301088
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202301088
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Actin nucleators safeguard replication forks by limiting nascent strand degradation

1
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  Addgene_12260
  
  DOI: 10.1093/nar/gkad369
  
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Dynamic profiling of medulloblastoma surfaceome

1
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  RRID:Addgene_12260
  
  DOI: 10.1186/s40478-023-01609-7
  
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Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons

1
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  Addgene_12260
  
  DOI: 10.1016/j.isci.2023.107044
  
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  RRID:Addgene_12260
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sciencedirect.com/science/article/pii/S2589004223011215
52.53.155.43 52.53.155.43

can-23-0269-html.html

1
1. scibot 08 Jul 2023
  
  in Public
  
  Addgene, 12260
  
  DOI: 10.1158/0008-5472.can-23-0269
  
  Resource: RRID:Addgene_12260
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260
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52.53.155.43/54e62d316063b1626eedcc4063c6657fd4e230c9/can-23-0269-html.html
www.nature.com www.nature.com

Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:Addgene_12260
  
  DOI: 10.1038/s41420-023-01526-7
  
  Resource: RRID:Addgene_12260
  
  Curator: @scibot
  
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  RRID:Addgene_12260
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nature.com/articles/s41420-023-01526-7
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TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:Addgene_12260
  
  DOI: 10.1016/j.cell.2023.06.005
  
  Resource: RRID:Addgene_12260
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0092867423006451
52.53.155.43 52.53.155.43

qiad076-html.html

1
1. scibot 07 Jul 2023
  
  in Public
  
  plasmid_12260
  
  DOI: 10.1093/jleuko/qiad076
  
  Resource: RRID:Addgene_12260
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260
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52.53.155.43/d58f6f13e6cc8ca0bc487138d6ae8d2f57dd2a0f/qiad076-html.html
www.sciencedirect.com www.sciencedirect.com

The anti-SARS-CoV-2 effect and mechanism of Chiehyuan herbal oral protection solution

1
1. scibot 06 Jul 2023
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.heliyon.2023.e17701
  
  Resource: RRID:Addgene_12260
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260
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sciencedirect.com/science/article/pii/S2405844023049095
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Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways

1
1. scibot 04 Jul 2023
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.112705
  
  Resource: RRID:Addgene_12260
  
  Curator: @jmitrevska
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260
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sciencedirect.com/science/article/pii/S2211124723007167
52.53.155.43 52.53.155.43

cd-22-0411-html.html

2
1. scibot 01 Jul 2023
  
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  RRID: Addgene_12260
  
  DOI: 10.1158/2159-8290.cd-22-0411
  
  Resource: RRID:Addgene_12260
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260
2. scibot 01 Jul 2023
  
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  plasmid_12260
  
  DOI: 10.1158/2159-8290.cd-22-0411
  
  Resource: RRID:Addgene_12260
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260
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52.53.155.43/453457acda6208aed297e8061921a5c2d2ddddf2/cd-22-0411-html.html
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Identification of XAF1 as an endogenous AKT inhibitor

1
1. scibot 29 Jun 2023
  
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  RRID:Addgene_12260
  
  DOI: 10.1016/j.celrep.2023.112690
  
  Resource: RRID:Addgene_12260
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12260
  
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  RRID:Addgene_12260 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S2211124723007015

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