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May 2023
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AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

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Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells

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Actuation of single downstream nodes in growth factor network steers immune cell migration

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Modeling human ectopic pregnancies with trophoblast and vascular organoids

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pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

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Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction

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Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21

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A prime editor mouse to model a broad spectrum of somatic mutations in vivo

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XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis

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MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

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Optimized metrics for orthogonal combinatorial CRISPR screens

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ncbi.nlm.nih.gov/pmc/articles/PMC10164157/
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Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro

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A rabies virus–based toolkit for efficient retrograde... : Neural Regeneration Research

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Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells

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Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus

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ncbi.nlm.nih.gov/pmc/articles/PMC10154558/
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CHD-associated enhancers shape human cardiomyocyte lineage commitment

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ncbi.nlm.nih.gov/pmc/articles/PMC10156167/
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Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR

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Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma

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Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition

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A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer

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ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
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L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification

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biorxiv.org/content/10.1101/2023.03.04.531072v1
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Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly

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KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress

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TOPK inhibits TNF-α-induced granulosa cell apoptosis via regulation SIRT1/p53

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Apr 2023
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Integrative dissection of gene regulatory elements at base resolution

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  DOI: 10.1016/j.xgen.2023.100318
  
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Dynamics of Chromatin Accessibility during Hematopoietic Stem Cell Differentiation into Progressively Lineage-Committed Progeny

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academic.oup.com/stmcls/advance-article/doi/10.1093/stmcls/sxad022/7083147
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Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis

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A tissue injury sensing and repair pathway distinct from host pathogen defense

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C9ORF72 suppresses JAK-STAT mediated inflammation

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Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity

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  DOI: 10.1158/2326-6066.CIR-22-0056
  
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aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
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Dual mTORC1/2 inhibition synergistically enhances AML cell death in combination with the BCL2 antagonist venetoclax

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aacrjournals.org/clincancerres/article/29/7/1332/718764/Dual-mTORC1-2-Inhibition-Synergistically-Enhances
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Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

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  DOI: 10.1158/2767-9764.CRC-23-0086
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10108886/
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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

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  DOI: 10.1016/j.ccell.2023.03.002
  
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PHLPP1 regulates PINK1-parkin signalling and life span

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CRISPR-suppressor scanning for systematic discovery of drug resistance mutations

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ncbi.nlm.nih.gov/pmc/articles/PMC10073897/
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RTF2 controls replication repriming and ribonucleotide excision at the replisome

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  DOI: 10.1101/2023.03.13.532415
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10054921/
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Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism

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  DOI: 10.1038/s41467-023-37454-4
  
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Asparagine starvation suppresses histone demethylation through iron depletion

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Phosphorylation barcodes direct biased chemokine signaling at CXCR3

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Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

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A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma

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ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas

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Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities

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PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection

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Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars

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Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

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Novel role of pre-replication complex component cell division cycle 6 in retinal neovascularization

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A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro

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Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells

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Stem cell-based modeling and single-cell multiomics reveal gene-regulatory mechanisms underlying human skeletal development

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Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals

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Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

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m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis

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FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation

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CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

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Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase

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Disease Modifying Osteoarthritis Drug Discovery Using A Temporal Phenotypic Reporter In Primary Human Chondrocytes

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Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells

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FAM193A is a positive regulator of p53 activity

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Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB

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Inhibition of RNA Polymerase III Augments the Anti-Cancer Properties of TNFα

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LCP1 Regulates Cell Motility in Chondrosarcoma and Correlates with Metastatic Potential and Poor Patient Outcomes

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The tyrosine phosphatase LAR acts as a receptor of the nidogen-tetanus toxin complex

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The effect of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly

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SYNGAP1 deficiency disrupts neoteny in human cortical neurons in vivo

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Inactivation of SARS-CoV-2 on Surfaces by Cold-Plasma-Generated Reactive Species

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A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses

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Mapping the dynamic cell surface interactome of high-density lipoprotein reveals Aminopeptidase N as modulator of its endothelial uptake

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EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons

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Feb 2023
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Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules

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HER2-driven breast cancer suppression by the JNK signaling pathway

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An adverse tumor-protective effect of IDO1 inhibition

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Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8+ T Cells

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PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma

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Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

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Archaic humans have contributed to large-scale variation in modern human T cell receptor genes

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Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs

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CRISPR-based large-scale modeling of loss-of-function mutations to investigate mechanisms of stress resistance in cancer

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ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions

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A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency

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PINK1-mediated mitophagy promotes oxidative phosphorylation and redox homeostasis to induce drug-tolerant persister cancer cells

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Monitoring cell fate in 3D organotypic human squamous epithelial cultures

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Piperlongumine conjugates induce targeted protein degradation

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Stress Granules determine the Development of Obesity-associated Pancreatic Cancer

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CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication

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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

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A FRET sensor for the real-time detection of long chain acyl-CoAs and synthetic ABHD5 ligands

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Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity

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The endothelial-enriched lncRNA LINC00607 mediates angiogenic function

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Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation

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Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies

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Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins

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CoQ Regulates Brown Adipose Tissue Respiration and Uncoupling Protein 1 Expression

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Attenuating iPSC reprogramming stress with dominant-negative BET peptides

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Optimized protocols for chromatin immunoprecipitation of exogenously expressed epitope-tagged proteins

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Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling

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TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis

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Protocol to study presynaptic protein synthesis in ex vivo mouse hippocampal slices using HaloTag technology

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Actin nucleators safeguard replication forks by limiting nascent strand degradation

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Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons

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An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes

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Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation

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The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction

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Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma

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Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers

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Oncogenic BRAFV600E induces microglial proliferation... : Neural Regeneration Research

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Acute COG inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra-Golgi recycling vesicles

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Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

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Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II–dependent fashion

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rupress.org/jcb/article/222/2/e202204100/213712/Fibroblasts-secrete-fibronectin-under-lamellipodia
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DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling

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A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistancePARP7 inhibitor CRISPR screen

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  RRID:Addgene_12259
  
  DOI: 10.1158/1535-7163.MCT-21-0841
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9769698/
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Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses

1
1. scibot 11 Jan 2023
  
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  Plasmid #12259 (Addgene)
  
  DOI: 10.1016/j.isci.2022.105887
  
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Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells

1
1. scibot 11 Jan 2023
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.xpro.2022.101992
  
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Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin

1
1. scibot 11 Jan 2023
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2022.12.016
  
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Resurrection of endogenous retroviruses during aging reinforces senescence

1
1. scibot 07 Jan 2023
  
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  plasmid_12259
  
  DOI: 10.1016/j.cell.2022.12.017
  
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MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor

1
1. scibot 07 Jan 2023
  
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  Addgene_12259
  
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Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis

1
1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.joca.2022.12.010
  
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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

1
1. scibot 06 Jan 2023
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.stem.2022.12.006
  
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Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

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1. scibot 02 Jan 2023
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2022.12.003
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00589-X
Dec 2022
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Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection

1
1. scibot 31 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1128/mbio.02446-22
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9765453/
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IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis

1
1. scibot 31 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1158/2767-9764.crc-22-0262
  
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Virus-like particle – mediated delivery of the RIG-I agonist M8 induces a type I interferon response and protects cells against viral infection

1
1. scibot 30 Dec 2022
  
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  plasmid_12259
  
  DOI: 10.3389/fcimb.2022.1079926
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9795031/
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The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities

1
1. scibot 29 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1007/s12035-022-03153-2
  
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link.springer.com/article/10.1007/s12035-022-03153-2
aacrjournals.org aacrjournals.org

IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis

1
1. scibot 24 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1158/2767-9764.CRC-22-0262
  
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aacrjournals.org/cancerrescommun/article/2/12/1545/711358/IL1-Expression-Driven-by-Androgen-Receptor-Absence
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Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing

1
1. scibot 24 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1158/0008-5472.CAN-21-2519
  
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aacrjournals.org/cancerres/article/82/17/3002/708290/Efficient-Correction-of-Oncogenic-KRAS-and-TP53
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IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury

1
1. scibot 24 Dec 2022
  
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  Addgene_12259
  
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ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

1
1. scibot 20 Dec 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.devcel.2022.11.015
  
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AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer

1
1. scibot 20 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1007/s00018-022-04638-y
  
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The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response

1
1. scibot 18 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111819
  
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Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection

1
1. scibot 18 Dec 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111817
  
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Generation and Analysis of hTERT-RPE1 VPS54 Knock-Out and Rescued Cell Lines

2
1. scibot 17 Dec 2022
  
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  plasmid_12259
  
  DOI: 10.1007/978-1-0716-2639-9_22
  
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  RRID:Addgene_12
  
  DOI: 10.1007/978-1-0716-2639-9_22
  
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Rapid COG Depletion in Mammalian Cell by Auxin-Inducible Degradation System

1
1. scibot 17 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1007/978-1-0716-2639-9_23
  
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link.springer.com/protocol/10.1007/978-1-0716-2639-9_23
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Engineered cell entry links receptor biology with single-cell genomics

1
1. scibot 17 Dec 2022
  
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  addgene_12259
  
  DOI: 10.1016/j.cell.2022.11.016
  
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A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates

1
1. scibot 11 Dec 2022
  
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  DOI: 10.1016/j.cell.2022.11.005
  
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USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

2
1. scibot 08 Dec 2022
  
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  12259
  
  DOI: 10.1016/j.celrep.2022.111653
  
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  DOI: 10.1016/j.celrep.2022.111653
  
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PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing

1
1. scibot 08 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.molcel.2022.11.010
  
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sciencedirect.com/science/article/pii/S1097276522010991
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Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma

1
1. scibot 03 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1158/2159-8290.CD-22-0287
  
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aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
www.embopress.org www.embopress.org

IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia

1
1. scibot 02 Dec 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.15252/emmm.202115631
  
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embopress.org/doi/10.15252/emmm.202115631
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SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia

1
1. scibot 01 Dec 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111727
  
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sciencedirect.com/science/article/pii/S2211124722016059
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BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis

1
1. scibot 01 Dec 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111728
  
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sciencedirect.com/science/article/pii/S2211124722016060
Nov 2022
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Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins

1
1. scibot 24 Nov 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111675
  
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sciencedirect.com/science/article/pii/S2211124722015492
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Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies

1
1. scibot 24 Nov 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111678
  
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sciencedirect.com/science/article/pii/S2211124722015522
52.53.155.43 52.53.155.43

Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis

1
1. scibot 22 Nov 2022
  
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  plasmid_12259
  
  DOI: 10.1093/hmg/ddac235
  
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52.53.155.43/cc79e40c92dade70c5729b9199717becabfd0bfe/ddac235-html.html
aacrjournals.org aacrjournals.org

p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness

1
1. scibot 22 Nov 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1158/1078-0432.CCR-22-1357
  
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aacrjournals.org/clincancerres/article/28/21/4757/709842/p53-Inhibits-Bmi-1-driven-Self-Renewal-and-Defines
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GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry

1
1. scibot 19 Nov 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.isci.2022.105481
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9668739/
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Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex

1
1. scibot 18 Nov 2022
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.isci.2022.105458
  
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Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation

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The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool

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Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis

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Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci

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Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma

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MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation

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Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway

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The phenotypic landscape of essential human genes

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Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice

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Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia

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Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system

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Multiphase coalescence mediates Hippo pathway activation

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Generation of a bovine cell line for gene engineering using an HIV-1-based lentiviral vector

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Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964

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HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex

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HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev

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ccr-22-1357-html.html

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Lentiviral vector mediated gene therapy for type I Dent disease effectively ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice

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Imaging Inflammasome Activation in Microglia

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m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress

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OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis

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Cell clusters adopt a collective amoeboid mode of migration in confined nonadhesive environments

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Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection

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The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies

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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis

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CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons

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Generation of a bovine cell line for gene engineering using an HIV-1-based lentiviral vector

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HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress

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POP1 inhibits MSU-induced inflammasome activation and ameliorates gout

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Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome

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The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes

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Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration

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Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfments

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Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

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Opto-katanin, an optogenetic tool for localized, microtubule disassembly

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A screening-compatible live cell fluorescence resonance energy transfer-based assay for modulation of Rho GTPase activity

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Determining glioma cell invasion and proliferation in ex vivo organotypic mouse brain slices using whole-mount immunostaining and tissue clearing

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sciencedirect.com/science/article/pii/S2666166722005834
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TGFBR3 supports anoikis through suppressing ATF4 signaling

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1. scibot 22 Sep 2022
  
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  Addgene_12259
  
  DOI: 10.1242/jcs.258396
  
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journals.biologists.com/jcs/article/135/17/jcs258396/276460/TGFBR3-supports-anoikis-through-suppressing-ATF4
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GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer

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1. scibot 22 Sep 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111344
  
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2. scibot 22 Sep 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111344
  
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sciencedirect.com/science/article/pii/S221112472201172X
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Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization

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1. scibot 22 Sep 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111361
  
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Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation

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1. scibot 22 Sep 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.3389/fendo.2022.932286
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9483015/
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Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin

1
1. scibot 21 Sep 2022
  
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  Plasmid pMD2.G
  
  DOI: 10.1016/j.celrep.2022.111390
  
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CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation

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1. scibot 18 Sep 2022
  
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  plasmid_12259
  
  DOI: 10.1016/j.xpro.2022.101682
  
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Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells

1
1. scibot 15 Sep 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.xpro.2022.101675
  
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SerpinB3 drives cancer stem cell survival in glioblastoma

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1. scibot 15 Sep 2022
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2022.111348
  
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NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

1
1. scibot 10 Sep 2022
  
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  RRID:Addgene_12259
  
  DOI: 10.1158/2159-8290.CD-22-0043
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437572/

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