4,927 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCDC113 promotes colorectal cancer tumorigenesis and metastasis via TGF-β signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11390942/
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    Tuberculosis in otherwise healthy adults with inherited TNF deficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC11390478/
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    A metabolic crosstalk between liposarcoma and muscle sustains tumor growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393074/
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    Engineered model of heart tissue repair for exploring fibrotic processes and therapeutic interventions
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393355/
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    Large-scale evaluation of the ability of RNA-binding proteins to activate exon inclusion
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    ncbi.nlm.nih.gov/pmc/articles/PMC11389820/
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    Persistent tailoring of MSC activation through genetic priming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11396059/
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    c-Myc alone is enough to reprogram fibroblasts into functional macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC11396436/
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    DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5
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    ncbi.nlm.nih.gov/pmc/articles/PMC10937187/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATM phosphorylation of CD98HC increases antiporter membrane localization and prevents chronic toxic glutamate accumulation in Ataxia telangiectasia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398575/
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    Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11418197/
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    Death-associated protein kinase 3 modulates migration and invasion of triple-negative breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11421662/
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    EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases*
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    ncbi.nlm.nih.gov/pmc/articles/PMC11421376/
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    Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11422168/
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    Induction of immortal-like and functional CAR T cells by defined factors
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    pmc.ncbi.nlm.nih.gov/articles/PMC10965394/
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    Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels
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    dx.doi.org/10.1093/hmg/ddae135
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    Nuclear body reorganization by the viral RNA kaposin promotes Kaposi’s sarcoma-associated herpesvirus gene expression
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    biorxiv.org/content/10.1101/2024.09.20.614208v1
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    Saturation mutagenesis-reinforced functional assays for disease-related genes
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    sciencedirect.com/science/article/pii/S0092867424009760
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    A sustained calcium response mediated by IP3 receptor anchoring to the desmosome is essential for apoptotic cell elimination
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    sciencedirect.com/science/article/pii/S0960982224011734
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    Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems
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    biorxiv.org/content/10.1101/2024.09.23.614524v1
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    The septin cytoskeleton is required for plasma membrane repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387490/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transiently formed nucleus-to-cilium microtubule arrays mediate senescence initiation in a KIFC3-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393428/
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    USP37 prevents premature disassembly of stressed replisomes by TRAIP
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398331/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and Characterization of Novel Small-Molecule Enhancers of the CUL3LZTR1 E3 Ligase KRAS Complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11420953/
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    SMYD5 is a regulator of the mild hypothermia response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11401508/
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    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    ncbi.nlm.nih.gov/pmc/articles/PMC11406439/
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    Glial fibrillary acidic protein is pathologically modified in Alexander disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11259701/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys
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    ncbi.nlm.nih.gov/pmc/articles/PMC11324798/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343478/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockout of the WD40 domain of ATG16L1 enhances foot and mouth disease virus replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11342673/
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    Immunogen characterization reveals an intrinsic hindrance in eliciting neutralizing antibodies against JN.1 variant
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    ncbi.nlm.nih.gov/pmc/articles/PMC11300904/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related hemoparasites
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    ncbi.nlm.nih.gov/pmc/articles/PMC11271486/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11269944/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11290356/
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    CircHIPK3 regulates cementoblast differentiation via the miR-10b-5p/DOHH/NF-κB axis
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    sciencedirect.com/science/article/pii/S0898656824003954
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    Identification of Cables1 as a critical host factor that promotes ALV-J replication via genome-wide CRISPR/Cas9 gene knockout screening
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    sciencedirect.com/science/article/pii/S0021925824023056
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    Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation
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    sciencedirect.com/science/article/pii/S1074761324004151
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity labeling reveals dynamic changes in the SQSTM1 protein network
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    ncbi.nlm.nih.gov/pmc/articles/PMC11401034/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413375/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FDA-approved disulfiram inhibits the NLRP3 inflammasome by regulating NLRP3 palmitoylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398858/
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    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1097276524007317
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    mTORC2-driven chromatin cGAS mediates chemoresistance through epigenetic reprogramming in colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11392818/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel lncRNA GM47544 modulates triglyceride metabolism by inducing ubiquitination-dependent protein degradation of APOC3
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399561/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo CAR T cell therapy against angioimmunoblastic T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11401350/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth: Insights into Its Underlying Mechanism in Glioblastoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394141/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deciphering regulation of FOXP3 expression in human conventional T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398386/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399086/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413235/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL18 functions as a Phenotypic Regulator in Src-Dependent Oncogenic Responses of HER2-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11414398/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413682/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A overexpression inhibits colorectal cancer cell migration through the regulation of epithelial‑mesenchymal transition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11406482/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405035/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-XL in a murine cell model of myeloid differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405755/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Building a novel TRUCK by harnessing the endogenous IFN-gamma promoter for cytokine expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405158/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of an antigen-based approach to noninvasively image CAR T cells in real time and as a predictive tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC11409975/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust Double Emulsions for Multicolor Fluorescence-Activated Cell Sorting
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    ncbi.nlm.nih.gov/pmc/articles/PMC11411495/
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    A Platform to Deliver Single and Bi-specific Cas9/guide RNA to Perturb Genes in Vitro and in Vivo
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    sciencedirect.com/science/article/pii/S1525001624004805
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388069/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feedback loop between plakophilin 4 and YAP signaling regulates keratinocyte differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11402648/
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    Epstein-Barr virus induces host shutoff extensively via BGLF5-independent mechanisms
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    sciencedirect.com/science/article/pii/S2211124724010945
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD21 promotes oncogenesis and lethal progression of prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388324/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Inhibiting Effect of GB-2, (+)-Catechin, Theaflavin, and Theaflavin 3-Gallate on Interaction between ACE2 and SARS-CoV-2 EG.5.1 and HV.1 Variants
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394907/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11370341/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399395/
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    Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation
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    sciencedirect.com/science/article/pii/S2211124724010908
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    Protein UFMylation regulates early events during ribosomal DNA-damage response
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    sciencedirect.com/science/article/pii/S2211124724010891
  67. www.nature.com www.nature.com
    Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency
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    nature.com/articles/s42255-024-01121-9
  68. www.biorxiv.org www.biorxiv.org
    Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents
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    biorxiv.org/content/10.1101/2024.09.04.611120v1
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    RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages
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    sciencedirect.com/science/article/pii/S1097276524007007
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    The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
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    sciencedirect.com/science/article/pii/S2211124724010404
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378439/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11377038/
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    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
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    sciencedirect.com/science/article/pii/S0092867424008985
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358483/
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    Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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    sciencedirect.com/science/article/pii/S2666379124004270
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    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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    sciencedirect.com/science/article/pii/S1074761324004072
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    CD14 is a decision-maker between Fas-mediated death and inflammation
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    sciencedirect.com/science/article/pii/S2211124724010362
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    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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    sciencedirect.com/science/article/pii/S1535610824003052
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
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    Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants
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    sciencedirect.com/science/article/pii/S1043661824003013
  81. Aug 2024
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
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    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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    sciencedirect.com/science/article/pii/S2211124724010337
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    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
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    sciencedirect.com/science/article/pii/S1074761324003765
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    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    sciencedirect.com/science/article/pii/S2211124724010325
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    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
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    sciencedirect.com/science/article/pii/S2451945624003192
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    Unveiling the oncogenic role of LZTS1 in colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11256987/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ELM2‐SANT Domain‐Containing Scaffolding Protein 1 Regulates Differentiation and Maturation of Cardiomyocytes Derived From Human‐Induced Pluripotent Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11255699/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong capacity of differentiated PD-L1 CAR-modified UCB-CD34+ cells and PD-L1 CAR-modified UCB-CD34+-derived NK cells in killing target cells and restoration of the anti-tumor function of PD-1-high exhausted T Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321137/
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321393/
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LACTB suppresses liver cancer progression through regulation of ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321384/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac
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    ncbi.nlm.nih.gov/pmc/articles/PMC10949499/
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321652/
  182. www.biorxiv.org www.biorxiv.org
    Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia
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    biorxiv.org/content/10.1101/2024.06.24.600514v1
  183. www.sciencedirect.com www.sciencedirect.com
    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
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    sciencedirect.com/science/article/pii/S193459092400256X
  184. www.sciencedirect.com www.sciencedirect.com
    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    sciencedirect.com/science/article/pii/S109727652400618X
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
  186. www.sciencedirect.com www.sciencedirect.com
    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    sciencedirect.com/science/article/pii/S2211124724009677
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitophagy defect mediates the aging‐associated hallmarks in Hutchinson–Gilford progeria syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC11296130/
  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11294820/
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292958/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11267830/
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytidine triphosphate synthase 1-mediated metabolic reprogramming promotes proliferation and drug resistance in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11268195/
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions
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    ncbi.nlm.nih.gov/pmc/articles/PMC11267888/
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC11270788/
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cathepsin L induces cellular senescence by upregulating CUX1 and p16INK4a
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    ncbi.nlm.nih.gov/pmc/articles/PMC11272106/
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP9X inhibits metastasis in pulmonary sarcomatoid carcinoma by regulating epithelial-mesenchymal transition, angiogenesis and immune infiltration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11283126/
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health
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    ncbi.nlm.nih.gov/pmc/articles/PMC11272588/
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulations of the mTORC2–GATA3 axis by an isorhamnetin activated endosomal–lysosomal system of the J774.1 macrophage-like cell line
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