5,649 Matching Annotations
  1. Feb 2024
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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    sciencedirect.com/science/article/pii/S221112472400024X
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    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
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    sciencedirect.com/science/article/pii/S1097276524000078
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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    cell.com/cell/fulltext/S0092-8674(24)00006-0
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    PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome
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    sciencedirect.com/science/article/pii/S0092867424000114
  6. Jan 2024
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    2.7 Å cryo-EM structure of human telomerase H/ACA ribonucleoprotein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811338/
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    Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10821871/
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    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    sciencedirect.com/science/article/pii/S1097276523010857
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    Dephosphorylation of neural wiring protein shootin1 by PP1 phosphatase regulates netrin-1-induced axon guidance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10196999/
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    AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10202939/
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
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    Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10192437/
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    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
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    CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10391547/
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    Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin
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    ncbi.nlm.nih.gov/pmc/articles/PMC10348765/
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    Cell-type-directed design of synthetic enhancers
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    nature.com/articles/s41586-023-06936-2
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    Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing
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    sciencedirect.com/science/article/pii/S2211124724000329
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    Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells
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    sciencedirect.com/science/article/pii/S1534580724000029
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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    sciencedirect.com/science/article/pii/S1097276523011218
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    Irreversible light-activated SpyLigation mediates split-protein assembly in 4D
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    link.springer.com/article/10.1038/s41596-023-00938-0
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    GLORI for absolute quantification of transcriptome-wide m6A at single-base resolution
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    link.springer.com/article/10.1038/s41596-023-00937-1
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13584
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    Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798561/
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    sciencedirect.com/science/article/pii/S2666379123006171
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    Cell surface RNAs control neutrophil recruitment
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    www-sciencedirect-com.proxy.uchicago.edu/science/article/pii/S0092867423014435
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    sciencedirect.com/science/article/pii/S2211124724000160
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    BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
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    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    science.org/doi/10.1126/scisignal.adg5289
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10769259/
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    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    sciencedirect.com/science/article/pii/S2589004224000221
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    Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC10564793/
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    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    sciencedirect.com/science/article/pii/S0304383524000296
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    SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
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    science.org/doi/10.1126/sciadv.adh2073
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin B6 competition in the tumor microenvironment hampers antitumor functions of NK cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10784745/
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    The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca2+ channels
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    ncbi.nlm.nih.gov/pmc/articles/PMC10769351/
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    SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape
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    science.org/doi/10.1126/scisignal.abq3362
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13587
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    ORF3c is expressed in SARS‐CoV‐2‐infected cells and inhibits innate sensing by targeting MAVS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10702836/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10746371/
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    Replicative fitness and pathogenicity of primate lentiviruses in lymphoid tissue, primary human and chimpanzee cells: relation to possible jumps to humans
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    sciencedirect.com/science/article/pii/S2352396423005315
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17044
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    Direct translation of incoming retroviral genomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10770327/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7
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    ncbi.nlm.nih.gov/pmc/articles/PMC10772347/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740387/
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    Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy
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    sciencedirect.com/science/article/pii/S1535610823004476
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13563
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
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    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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    sciencedirect.com/science/article/pii/S0092867423013478
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    HMGB1 in exosomes derived from gastric cancer cells induces M2-like macrophage polarization by inhibiting the NF-κB signaling pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbin.12110
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    Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus
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    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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    sciencedirect.com/science/article/pii/S002228362300551X
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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    sciencedirect.com/science/article/pii/S1097276523010328
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    PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5
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    sciencedirect.com/science/article/pii/S0166354224000056
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    SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency
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    sciencedirect.com/science/article/pii/S0092867423013995
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
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    cAMP-phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13572
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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  62. Dec 2023
  63. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13568
  64. www.biorxiv.org www.biorxiv.org
    New submission 31/07/2023, 09:07:20
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    biorxiv.org/content/10.1101/2023.06.24.546170v2
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    An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
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    sciencedirect.com/science/article/pii/S2211124723015693
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    sciencedirect.com/science/article/pii/S009286742301276X
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    sciencedirect.com/science/article/pii/S2666379123005591
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    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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    sciencedirect.com/science/article/pii/S2211124723016200
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    The HLA-II immunopeptidome of SARS-CoV-2
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    sciencedirect.com/science/article/pii/S221112472301608X
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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    sciencedirect.com/science/article/pii/S0896627323008942
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    Subcytoplasmic location of translation controls protein output
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    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
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    sciencedirect.com/science/article/pii/S2211124723015309
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    TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
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    sciencedirect.com/science/article/pii/S2589004223026949
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    Brain-wide circuit-specific targeting of astrocytes
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    sciencedirect.com/science/article/pii/S2667237523003247
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    Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379123004962
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    Strengthening E-cadherin adhesion via antibody-mediated binding stabilization
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    sciencedirect.com/science/article/pii/S0969212623004045
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    sciencedirect.com/science/article/pii/S2211124723015280
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    sciencedirect.com/science/article/pii/S2211124723015930
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723015358
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    iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
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    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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    MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes
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    Synonymous codon usage regulates translation initiation
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    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    sciencedirect.com/science/article/pii/S2211124723015723
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
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    Androgen Receptor/AP-1 Activates UGT2B15 Transcription to Promote Esophageal Squamous Cell Carcinoma Invasion
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    mdpi.com/2072-6694/15/24/5719
  90. www.tandfonline.com www.tandfonline.com
    Identification of putative allosteric inhibitors of BCKDK via virtual screening and biological evaluation
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    tandfonline.com/doi/abs/10.1080/14756366.2023.2290458
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Propylene glycol inactivates respiratory viruses and prevents airborne transmission
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