5,186 Matching Annotations
  1. Apr 2023
  2. www.sciencedirect.com www.sciencedirect.com
    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S266637912300112X
  3. reader.elsevier.com reader.elsevier.com
    Phosphorylation barcodes direct biased chemokine signaling at CXCR3
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    reader.elsevier.com/reader/sd/pii/S2451945623000855
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ad26.COV2.S and SARS-CoV-2 Spike Protein Ferritin Nanoparticle Vaccine Protect Against SARS-CoV-2 Omicron BA.5 Challenge in Macaques
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040355/
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    γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
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    sciencedirect.com/science/article/pii/S0896627323002088
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    The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
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    embopress.org/doi/full/10.15252/embj.2022112953
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    Targeted m6A demethylation of ITGA6 mRNA by a multisite dCasRx–m6A editor inhibits bladder cancer development
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    sciencedirect.com/science/article/pii/S2090123223000929
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    Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration
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    sciencedirect.com/science/article/pii/S2589004223004947
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    sciencedirect.com/science/article/pii/S1534580723000990
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    Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
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    sciencedirect.com/science/article/pii/S2666979X23000599
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    A general method for quantitative fractionation of mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040634/
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    Characterization of heterogeneous metabolism in hepatocellular carcinoma identifies new therapeutic target and treatment strategy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10060979/
  13. Mar 2023
  14. www.biorxiv.org www.biorxiv.org
    Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A
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    biorxiv.org/content/10.1101/2023.02.17.528918v1
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    Screening of Efficient Adjuvants for the RBD-Based Subunit Vaccine of SARS-CoV-2
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    mdpi.com/2076-393X/11/4/713
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    sciencedirect.com/science/article/pii/S258900422300487X
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    Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
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    sciencedirect.com/science/article/pii/S2211124723003327
  18. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Switching ubiquitous and muscle-specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine-tunes complex IV activity
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201223RR
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    A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro
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    sciencedirect.com/science/article/pii/S2666166723001442
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    Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120
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    sciencedirect.com/science/article/pii/S2451945623000624
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    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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    sciencedirect.com/science/article/pii/S2211124723001900
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    sciencedirect.com/science/article/pii/S2666166723001570
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10034470/
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    The acetylase activity of Cdu1 protects Chlamydia effectors from degradation to regulate bacterial exit from infected cells
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    biorxiv.org/content/10.1101/2023.02.28.530337v2
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    Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
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    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    sciencedirect.com/science/article/pii/S0021925823002636
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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    Differential Optineurin expression controls TGFβ signaling and is a key determinant for metastasis of triple negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34483
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC9957656/
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    A combinatorial approach to uncover an additional Integrator subunit
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    ER proteostasis regulators cell-non-autonomously control sleep
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    europepmc.org/article/med/36924492
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging Tumor Microenvironment Infiltration in Pancreatic Cancer to Identify Gene Signatures Related to Prognosis and Immunotherapy Response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10000708/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10014071/
  36. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    CEBPB upregulates P4HA2 to promote the malignant biological behavior in IDH1 wildtype glioma
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    faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.202201244RRRR
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    Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation
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    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes
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    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2352396423000658
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
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    ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
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    Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway
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    nature.com/articles/s12276-023-00957-7
  45. link.springer.com link.springer.com
    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
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    link.springer.com/article/10.1007/s12035-023-03281-3
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    S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
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    link.springer.com/article/10.1186/s13062-023-00364-y
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9978885/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile
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    ncbi.nlm.nih.gov/pmc/articles/PMC9902290/
  49. www.biorxiv.org www.biorxiv.org
    A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
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    biorxiv.org/content/10.1101/2023.01.31.526483v3
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16018
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16046
  53. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16050
  54. www.biorxiv.org www.biorxiv.org
    High-throughput screening of functional neo-antigens and their specific TCRs via the Jurkat reporter system combined with droplet microfluidics
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    biorxiv.org/content/10.1101/2023.02.20.529171v1
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC9961888/
  56. Feb 2023
  57. academic.oup.com academic.oup.com
    Follistatin forms a stable complex with Inhibin A that does not interfere with Activin A antagonism
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    academic.oup.com/endo/article/164/3/bqad017/7010688
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    E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity
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    sciencedirect.com/science/article/pii/S1097276523000424
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    Illuminating cellular and extracellular vesicle-mediated communication via a split-Nanoluc reporter in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2667237523000231
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    An adverse tumor-protective effect of IDO1 inhibition
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    sciencedirect.com/science/article/pii/S2666379123000332
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein composition of axonal dopamine release sites in the striatum
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    ncbi.nlm.nih.gov/pmc/articles/PMC9937654/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9388591/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9924825/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
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    CRISPR activation screening in a mouse model for drivers of hepatocellular carcinoma growth and metastasis
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    HSF1 activates the FOXO3a–ΔNp63α–CDK4 axis to promote head and neck squamous cell carcinoma cell proliferation and tumor growth
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    Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility
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    nature.com/articles/s41596-022-00795-3
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    XPO1 intensifies sorafenib resistance by stabilizing acetylation of NPM1 and enhancing epithelial-mesenchymal transition in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S0753332223001907
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC9910834/
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    Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9917443/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs
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    ncbi.nlm.nih.gov/pmc/articles/PMC9910744/
  73. 52.53.155.43 52.53.155.43
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    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9890133/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9780084/
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    A new means of energy supply driven by terahertz photons recovers related neural activity
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    Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
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    link.springer.com/article/10.1186/s12964-023-01042-2
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9894587/
  79. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
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    nature.com/articles/s41467-023-36058-2
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    Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy
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    nature.com/articles/s41467-022-35583-w
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    Unique effect of clozapine on adenosine A2A-dopamine D2 receptor heteromerization
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9834170/
  84. Jan 2023
  85. www.sciencedirect.com www.sciencedirect.com
    Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice
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    Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress
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    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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    sciencedirect.com/science/article/pii/S1934590922004878
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing screens map mutations affecting interferon-γ signaling in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9942875/
  89. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
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    science.org/doi/10.1126/scisignal.abh1083
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination
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    ncbi.nlm.nih.gov/pmc/articles/PMC9847566/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts
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  186. Nov 2022
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