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Nov 2021
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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

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1. scibot 10 Nov 2021
  
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Modulating mesendoderm competence during human germ layer differentiation

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RNA-responsive elements for eukaryotic translational control

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  DOI: 10.1038/s41587-021-01068-2
  
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nature.com/articles/s41587-021-01068-2
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IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay

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1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.71966
  
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A functional genetic toolbox for human tissue-derived organoids

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1. scibot 05 Nov 2021
  
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elifesciences.org/articles/67886
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AKAP79 enables calcineurin to directly suppress protein kinase A activity

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1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.68164
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8560092/
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A multi-omic single-cell landscape of human gynecologic malignancies

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A synthetic gene circuit for imaging-free detection of signaling pulses

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Oct 2021
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MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer

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1. scibot 29 Oct 2021
  
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Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells

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1. scibot 27 Oct 2021
  
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jneurosci.org/content/41/42/8710
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GCN2 adapts protein synthesis to scavenging-dependent growth

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1. scibot 27 Oct 2021
  
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Direct conversion of adult fibroblasts into motor neurons

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1. scibot 26 Oct 2021
  
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Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma

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1. scibot 23 Oct 2021
  
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Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope

1
1. scibot 23 Oct 2021
  
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  DOI: 10.7554/eLife.65672
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8523159/
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Exocyst complex mediates recycling of internal cilia

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1. scibot 22 Oct 2021
  
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Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications

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1. scibot 22 Oct 2021
  
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  DOI: 10.1016/j.xpro.2021.100874
  
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A synaptic temperature sensor for body cooling

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1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.neuron.2021.10.001
  
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Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress

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1. scibot 21 Oct 2021
  
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NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression

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1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109856
  
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BPS Publications

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1. scibot 20 Oct 2021
  
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  DOI: 10.1111/bph.15631
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15631
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Andrographolide prevents bone loss via targeting ERRalpha-regulated metabolic adaption of osteoclastogenesis

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1. scibot 16 Oct 2021
  
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  DOI: 10.1111/bph.15614
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15614
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Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival

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Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling

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1. scibot 14 Oct 2021
  
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sciencedirect.com/science/article/pii/S0021925821010966
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A highly potent antibody effective against SARS-CoV-2 variants of concern

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ncbi.nlm.nih.gov/pmc/articles/PMC8452523/
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Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation

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1. scibot 09 Oct 2021
  
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sciencedirect.com/science/article/pii/S1534580721007334
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Interpretation of cancer mutations using a multiscale map of protein systems

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1. scibot 08 Oct 2021
  
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  DOI: 10.1126/science.abf3067
  
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science.org/doi/10.1126/science.abf3067
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Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis

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1. scibot 06 Oct 2021
  
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  DOI: 10.1165/rcmb.2020-0544OC
  
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Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

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Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines

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Development and Initial Characterization of Cellular Models for COG Complex-Related CDG-II Diseases

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  DOI: 10.3389/fgene.2021.733048
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8484713/
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A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system

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  DOI: 10.1038/s41598-021-98657-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
Sep 2021
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In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

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Revisiting astrocyte to neuron conversion with lineage tracing in vivo

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1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.09.005
  
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In situ observation of mitochondrial biogenesis as the early event of apoptosis

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1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.isci.2021.103038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8441175/
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PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

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The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

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Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging

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Assessing the Wnt-reactivity of cytonemes of mouse embryonic stem cells using a bioengineering approach

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  DOI: 10.1016/j.xpro.2021.100813
  
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Pro-inflammatory and proliferative microglia drive progression of glioblastoma

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ZFP36L2 Role in Thyroid Functionality

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The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy

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Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2

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Cilium induction triggers differentiation of glioma stem cells

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HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis

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Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs

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UV-induced reduction in Polycomb repression promotes epidermal pigmentation

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Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability

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Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

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1. scibot 26 Aug 2021
  
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Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy

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A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells

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NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

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Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR)

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Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis

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The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder

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A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

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Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro

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  DOI: 10.1016/j.cels.2021.07.003
  
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Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide

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HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

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Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes

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Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma

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Synthesis and Degradation of Adenosine 5′-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases

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A flow cytometry-based assay for serological detection of anti-spike antibodies in COVID-19 patients

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  DOI: 10.1016/j.cell.2016.12.036
  
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Interspecies Chimerism with Mammalian Pluripotent Stem Cells

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Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring

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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

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Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer

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Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

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Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects

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ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

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sciencedirect.com/science/article/pii/S1550413118307344
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Subcellular drug targeting illuminates local kinase action

1
1. scibot 06 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.7554/eLife.52220
  
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Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats

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  Addgene_12259
  
  DOI: 10.1016/j.chom.2021.07.005
  
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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1. scibot 06 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2021.07.007
  
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Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells

1
1. scibot 06 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.cmet.2021.07.015
  
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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity

1
1. scibot 05 Aug 2021
  
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  addgene_12259
  
  DOI: 10.1016/j.chom.2018.11.001
  
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The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation

1
1. scibot 04 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109468
  
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Untitled document

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Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation

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1. scibot 04 Aug 2021
  
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  Addgene_12259
  
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Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells

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1. scibot 03 Aug 2021
  
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  Addgene 12259
  
  DOI: 10.1016/j.chembiol.2021.07.011
  
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution

1
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109460
  
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DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression

1
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.10.025
  
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Jul 2021
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Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia

1
1. scibot 31 Jul 2021
  
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  Addgene_12259
  
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Untitled document

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  DOI: 10.1016/j.stem.2019.02.006
  
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Widespread and Functional RNA Circularization in Localized Prostate Cancer

1
1. scibot 31 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2019.01.025
  
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  DOI: 10.7554/eLife.43511
  
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TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma

1
1. scibot 30 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.12.017
  
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Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype

1
1. scibot 30 Jul 2021
  
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  Addgene 12259
  
  DOI: 10.1016/j.celrep.2019.12.002
  
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Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A

1
1. scibot 30 Jul 2021
  
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  AddgeneCat# 12259
  
  DOI: 10.1016/j.celrep.2019.11.066
  
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Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade

1
1. scibot 30 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.devcel.2019.11.012
  
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Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses

1
1. scibot 30 Jul 2021
  
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  vsv-g expression vector (pMD2.G) (lentiviral helper plasmid)
  
  DOI: 10.1016/j.cell.2019.09.011
  
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High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

1
1. scibot 30 Jul 2021
  
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  pMDG.2
  
  DOI: 10.1038/s41551-019-0454-8
  
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nature.com/articles/s41551-019-0454-8
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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

1
1. scibot 30 Jul 2021
  
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  pMD2.G
  
  DOI: 10.1016/j.molcel.2019.07.021
  
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Untitled document

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  plasmid_12259
  
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  RRID:Addgene_12
  
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The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression

1
1. scibot 30 Jul 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.molcel.2018.01.011
  
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Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection

1
1. scibot 29 Jul 2021
  
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  Plasmid #12259
  
  DOI: 10.1016/j.celrep.2019.10.129
  
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Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits

1
1. scibot 29 Jul 2021
  
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  Addgene:12259
  
  DOI: 10.1016/j.neuron.2019.10.002
  
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Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

1
1. scibot 29 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.cell.2019.10.044
  
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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

1
1. scibot 29 Jul 2021
  
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  Addgene plasmid #12259
  
  DOI: 10.1016/j.celrep.2019.10.032
  
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Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4

1
1. scibot 29 Jul 2021
  
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  Addgene plasmid Cat# 12259
  
  DOI: 10.1016/j.celrep.2019.10.026
  
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DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression

1
1. scibot 29 Jul 2021
  
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  Addgene12259
  
  DOI: 10.1016/j.celrep.2019.10.025
  
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Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts

1
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  Addgene #12259
  
  DOI: 10.1038/s41598-019-52294-3
  
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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

1
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  RRID:Addgene_12259
  
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Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

1
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ebiom.2019.08.074
  
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sciencedirect.com/science/article/pii/S2352396419305961
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Profilin-Mediated Actin Allocation Regulates the Growth of Epithelial Microvilli

1
1. scibot 29 Jul 2021
  
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  Addgene #12259
  
  DOI: 10.1016/j.cub.2019.08.051
  
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
1. scibot 29 Jul 2021
  
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  Addgene12259
  
  DOI: 10.1016/j.ccell.2019.08.006
  
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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

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1. scibot 29 Jul 2021
  
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  Addgene Plasmid #12259
  
  DOI: 10.1016/j.ccell.2019.08.005
  
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Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion

1
1. scibot 29 Jul 2021
  
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  Addgene Plasmid:12259
  
  DOI: 10.1016/j.celrep.2019.08.017
  
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Identifying chemogenetic interactions from CRISPR screens with drugZ

1
1. scibot 29 Jul 2021
  
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  Addgene #12259
  
  DOI: 10.1186/s13073-019-0665-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6706933/
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TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.07.086
  
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A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells

1
1. scibot 29 Jul 2021
  
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  Addgene plasmids #12259
  
  DOI: 10.15252/embr.201948235
  
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embopress.org/doi/full/10.15252/embr.201948235
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Essential thrombocytosis attributed to <Emphasis Type="Italic">JAK2</Emphasis>-T875N germline mutation

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene 12259
  
  DOI: 10.1007/s12185-019-02725-8
  
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A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer

1
1. scibot 29 Jul 2021
  
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  Plasmid ID: #12259
  
  DOI: 10.1016/j.molcel.2019.06.010
  
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2019.06.014
  
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sciencedirect.com/science/article/pii/S0092867419306774
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PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

1
1. scibot 29 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.molcel.2019.05.030
  
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sciencedirect.com/science/article/pii/S1097276519304022
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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2019.05.013
  
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BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

1
1. scibot 29 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.cell.2019.06.005
  
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

1
1. scibot 29 Jul 2021
  
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  pMD2-VSVG
  
  DOI: 10.1016/j.celrep.2019.07.027
  
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sciencedirect.com/science/article/pii/S2211124719309246
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Untitled document

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  plasmid_12259
  
  DOI: 10.1038/s41421-018-0068-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.neo.2019.02.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6426874/
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Efficient and robust NK-Cell transduction with Baboon Envelope pseudotyped lentivector: a major tool for immunotherapy

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1101/625285
  
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biorxiv.org/content/10.1101/625285v1
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  Addgene_12259
  
  DOI: 10.1523/ENEURO.0135-18.2018
  
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eneuro.org/content/5/5/ENEURO.0135-18.2018
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Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

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1. scibot 28 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2019.04.036
  
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sciencedirect.com/science/article/pii/S0092867419304556
elifesciences.org elifesciences.org

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors

1
1. scibot 28 Jul 2021
  
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  RRID:Addgene_ 12259
  
  DOI: 10.7554/eLife.43653
  
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elifesciences.org/articles/43653
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Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

1
1. scibot 28 Jul 2021
  
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  Addgene: 12259
  
  DOI: 10.1016/j.ccell.2019.01.010
  
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Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture

1
1. scibot 28 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.cell.2018.11.012
  
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www.jneurosci.org www.jneurosci.org

Calcium Channel Subunit α2δ4 Is Regulated by Early Growth Response 1 and Facilitates Epileptogenesis

1
1. scibot 28 Jul 2021
  
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  pMD2.G
  
  DOI: 10.1523/JNEUROSCI.1731-18.2019
  
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jneurosci.org/content/39/17/3175
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 28 Jul 2021
  
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  Addgene #12259
  
  DOI: 10.1016/j.cmet.2019.01.020
  
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sciencedirect.com/science/article/pii/S1550413119300208
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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

1
1. scibot 28 Jul 2021
  
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  Addgene#12259
  
  DOI: 10.1016/j.immuni.2019.01.007
  
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sciencedirect.com/science/article/pii/S1074761319300305
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Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

1
1. scibot 28 Jul 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.stem.2018.06.001
  
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sciencedirect.com/science/article/pii/S1934590918302832
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Untitled document

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  RRID:Addgene_12259
  
  DOI: 10.1016/j.neo.2019.02.005
  
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sciencedirect.com/science/article/pii/S1476558618305001
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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

1
1. scibot 27 Jul 2021
  
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  RRID_Addgene_12259
  
  DOI: 10.1016/j.ccell.2019.12.007
  
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sciencedirect.com/science/article/pii/S153561081930577X
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Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction

1
1. scibot 27 Jul 2021
  
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  RRID: Addgene plasmid_12259
  
  DOI: 10.1016/j.immuni.2019.08.012
  
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sciencedirect.com/science/article/pii/S1074761319303632
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Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.cels.2018.10.008
  
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sciencedirect.com/science/article/pii/S2405471218304332
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Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.devcel.2018.10.026
  
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sciencedirect.com/science/article/pii/S1534580718308803
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Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.celrep.2018.10.082
  
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sciencedirect.com/science/article/pii/S2211124718316863
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Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.celrep.2018.10.074
  
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sciencedirect.com/science/article/pii/S2211124718316784
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Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.celrep.2018.10.100
  
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sciencedirect.com/science/article/pii/S2211124718317224
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Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.cels.2018.10.010
  
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sciencedirect.com/science/article/pii/S2405471218304356
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Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome

1
1. scibot 27 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.molcel.2018.10.028
  
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sciencedirect.com/science/article/pii/S1097276518308888
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  Addgene_12259
  
  DOI: 10.1016/j.cub.2018.08.060
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6224479/
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Untitled document

1
1. scibot 27 Jul 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.stem.2017.08.018
  
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  Curator: @evieth
  
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  RRIDCUR:NotRRID RRID:Addgene_12259 RRIDCUR:Unresolved
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ncbi.nlm.nih.gov/pmc/articles/PMC5644510/
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MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux

1
1. scibot 27 Jul 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.stem.2017.08.018
  
  Resource: RRID:Addgene_12259
  
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Delivering progranulin to neuronal lysosomes protects against excitotoxicity

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1. scibot 24 Jul 2021
  
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  DOI: 10.1016/j.jbc.2021.100993
  
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Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis

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1. scibot 23 Jul 2021
  
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  DOI: 10.7554/eLife.67828
  
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Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function

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1. scibot 22 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109416
  
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A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers

1
1. scibot 22 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1083/jcb.202005173
  
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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

1
1. scibot 22 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2021.06.016
  
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

1
1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.06.028
  
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ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

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1. scibot 21 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.isci.2021.102758
  
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Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection

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1. scibot 20 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1371/journal.ppat.1009715
  
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BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells

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1. scibot 14 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109359
  
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Active elimination of intestinal cells drives oncogenic growth in organoids

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1. scibot 09 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109307
  
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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

1
1. scibot 09 Jul 2021
  
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  plasmid_12259
  
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Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

1
1. scibot 08 Jul 2021
  
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  RRID:Addgene_12259
  
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Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit

1
1. scibot 07 Jul 2021
  
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  plasmid_12259
  
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Highly efficient manipulation of nervous system gene expression with NEPTUNE

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.crmeth.2021.100043
  
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Multiplexed bioluminescence-mediated tracking of DNA double-strand break repairs in vitro and in vivo

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1. scibot 01 Jul 2021
  
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  plasmid_12259
  
  DOI: 10.1038/s41596-021-00564-8
  
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BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion

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1. scibot 01 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.7554/eLife.63254
  
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Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration

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Jun 2021
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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

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1. scibot 30 Jun 2021
  
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RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis

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1. scibot 26 Jun 2021
  
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Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

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HepaCAM controls astrocyte self-organization and coupling

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  DOI: 10.1016/j.neuron.2021.05.025
  
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The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency

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1. scibot 24 Jun 2021
  
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  DOI: 10.1371/journal.pgen.1009587
  
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Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

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Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion

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NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

1
1. scibot 17 Jun 2021
  
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
1. scibot 17 Jun 2021
  
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  plasmid_12259
  
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Tailored generation of insulin producing cells from canine mesenchymal stem cells derived from bone marrow and adipose tissue

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ncbi.nlm.nih.gov/pmc/articles/PMC8196068/
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Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression

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  DOI: 10.1080/15548627.2021.1936356
  
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Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response

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Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion

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  DOI: 10.1016/j.xpro.2021.100603
  
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TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

1
1. scibot 12 Jun 2021
  
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  Plasmid #12259
  
  DOI: 10.1016/j.cmet.2021.05.014
  
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Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states

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Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis

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  plasmid_12259
  
  DOI: 10.7554/eLife.68311
  
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DMA-tudor interaction modules control the specificity of in vivo condensates

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Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia

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Pericentromeric Satellite III transcripts induce etoposide resistance

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1. scibot 02 Jun 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1038/s41419-021-03810-9
  
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May 2021
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Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors

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1. scibot 29 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cels.2021.05.002
  
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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

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1. scibot 28 May 2021
  
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  CAT#12259
  
  DOI: 10.1016/j.cell.2021.04.037
  
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A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells

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1. scibot 27 May 2021
  
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  DOI: 10.1016/j.xpro.2021.100561
  
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SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A

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1. scibot 27 May 2021
  
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  plasmid_12259
  
  DOI: 10.7554/eLife.64930
  
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Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs

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1. scibot 22 May 2021
  
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  DOI: 10.1038/s42003-021-02104-2
  
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The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development

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1. scibot 22 May 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.3390/cells10051233
  
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mdpi.com/2073-4409/10/5/1233
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Adhesion-mediated mechanosignaling forces mitohormesis

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1. scibot 21 May 2021
  
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  DOI: 10.1016/j.cmet.2021.04.017
  
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NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

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1. scibot 19 May 2021
  
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  DOI: 10.1126/sciadv.abf7114
  
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Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers

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1. scibot 19 May 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109144
  
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sciencedirect.com/science/article/pii/S2211124721004836

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