517 Matching Annotations
  1. Oct 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes
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    sciencedirect.com/science/article/pii/S2211124723011609
  3. Sep 2023
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    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
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    sciencedirect.com/science/article/pii/S1931312823003281
  5. 52.53.155.43 52.53.155.43
    Neuronal AR regulates glucose homeostasis and energy expenditure in lean female mice with androgen excess
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    52.53.155.43/3879cee9653b10d45813ef8c7ed9945ed72f559d/bqad141-html.html
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    Deubiquitylating Enzyme OTUB1 Facilitates Neuronal Survival After Intracerebral Hemorrhage Via Inhibiting NF-κB-triggered Apoptotic Cascades
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    link.springer.com/article/10.1007/s12035-023-03676-2
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    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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    sciencedirect.com/science/article/pii/S2589004223018370
  8. Aug 2023
  9. www.embopress.org www.embopress.org
    Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome
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    embopress.org/doi/10.15252/embr.202357233
  10. 52.53.155.43 52.53.155.43
    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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    52.53.155.43/8a075ef675e11ca05cb4fe9fd629f036036ec570/PIIS2211124723009798-html.html
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    PIIS2589004223016784-html.html
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  12. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
  13. 52.53.155.43 52.53.155.43
    PROTAC targeting cyclophilin A controls virus-induced cytokine storm
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    52.53.155.43/e2f87aa1f912bf54befa1c581767df6b21a2ec48/PIIS2589004223016127-html.html
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10411973/
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    Hedgehog receptors exert immune-surveillance roles in the epidermis across species
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    sciencedirect.com/science/article/pii/S2211124723009403
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10374607/
  17. Jul 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10358659/
  19. 52.53.155.43 52.53.155.43
    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
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    52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP2 downregulation in T cells ameliorates lipopolysaccharide-induced inflammation of the large intestine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10347374/
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    sciencedirect.com/science/article/pii/S2211124723008239
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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    sciencedirect.com/science/article/pii/S2666379123002483
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    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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    sciencedirect.com/science/article/pii/S1535610823002179
  24. 52.53.155.43 52.53.155.43
    HIV-1 Tat Upregulates TREM1 Expression in Human Microglia
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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    sciencedirect.com/science/article/pii/S0753332223008284
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    sciencedirect.com/science/article/pii/S1074761323002637
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    Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production
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    sciencedirect.com/science/article/pii/S2211124723007192
  28. Jun 2023
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    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
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    sciencedirect.com/science/article/pii/S2589004223011902
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    The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity
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    sciencedirect.com/science/article/pii/S1074761323002376
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    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S2589004223011926
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    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
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    mdpi.com/2076-3921/12/6/1303
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    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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    sciencedirect.com/science/article/pii/S1074761323002315
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    Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
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    sciencedirect.com/science/article/pii/S2211124723006587
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    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
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    sciencedirect.com/science/article/pii/S1550413123002097
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    SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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    Arginine depletion attenuates renal cystogenesis in tuberous sclerosis complex model
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233356/
  39. www.cell.com www.cell.com
    Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis
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    cell.com/cell-host-microbe/fulltext/S1931-3128(23)00200-7
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    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
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    sciencedirect.com/science/article/pii/S009286742300524X
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    Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging
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  42. May 2023
  43. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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    sciencedirect.com/science/article/pii/S1097276523003350
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lacking ARHGAP25 mitigates the symptoms of autoantibody-induced arthritis in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10208528/
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610823001629
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    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
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    sciencedirect.com/science/article/pii/S0006295223002034
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    A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response
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    sciencedirect.com/science/article/pii/S2589004223008854
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    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
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    sciencedirect.com/science/article/pii/S2589004223008477
  49. journals.aai.org journals.aai.org
    cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway
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    journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
  50. 52.53.155.43 52.53.155.43
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  51. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2026/04000/the_cullin3_ring_e3_ubiquitin_ligase_complex_and.44.aspx
  52. www.mdpi.com www.mdpi.com
    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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    mdpi.com/2076-3921/10/9/1387/htm
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Premorbid use of selective beta-blockers improves sepsis incidence and course: Human cohort and animal model studies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10151496/
  54. link.springer.com link.springer.com
    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
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    link.springer.com/article/10.1186/s12974-023-02784-z
  55. Apr 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
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    sciencedirect.com/science/article/pii/S2666379123001349
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC10195032/
  58. link.springer.com link.springer.com
    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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    link.springer.com/article/10.1186/s12935-023-02884-z
  59. link.springer.com link.springer.com
    N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1
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    link.springer.com/article/10.1186/s12974-023-02754-5
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOCS1 regulates a subset of NFκB-target genes through direct chromatin binding and defines macrophage functional phenotypes.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10068561/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mannose-coated nanozyme for relief from chemotherapy-induced peripheral neuropathic pain
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    ncbi.nlm.nih.gov/pmc/articles/PMC10074233/
  62. www.sciencedirect.com www.sciencedirect.com
    Adipocyte-derived chemerin rescues lipid overload-induced cardiac dysfunction
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  63. www.sciencedirect.com www.sciencedirect.com
    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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    sciencedirect.com/science/article/pii/S2211124723003510
  64. Mar 2023
  65. 52.53.155.43 52.53.155.43
    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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    52.53.155.43/a2856e34c76df1f90e78f95405a1557ff7dcdfbe/ajpheart.00390.2022-html.html
  66. link.springer.com link.springer.com
    Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation
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    link.springer.com/article/10.1186/s12951-023-01853-y
  67. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic CD161−CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus
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    sciencedirect.com/science/article/pii/S2352396423000725
  68. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16041
  69. Feb 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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  71. www.sciencedirect.com www.sciencedirect.com
    Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease
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    sciencedirect.com/science/article/pii/S2666379123000459
  72. journals.lww.com journals.lww.com
    Macrophage migration inhibitory factor facilitates... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/08000/Macrophage_migration_inhibitory_factor_facilitates.38.aspx
  73. www.sciencedirect.com www.sciencedirect.com
    Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linear ubiquitination induces NEMO phase separation to activate NF-κB signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC9889916/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9893022/
  76. Jan 2023
  77. www.sciencedirect.com www.sciencedirect.com
    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124723000165
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    sciencedirect.com/science/article/pii/S221112472300013X
  79. www.nature.com www.nature.com
    Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
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    nature.com/articles/s41556-022-01056-x
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
  81. journals.lww.com journals.lww.com
    Oncogenic BRAFV600E induces microglial proliferation... : Neural Regeneration Research
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  82. 52.53.155.43 52.53.155.43
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1074761322006045
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    Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis
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    sciencedirect.com/science/article/pii/S2211124722018496
  85. www.nature.com www.nature.com
    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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    nature.com/articles/s41419-022-05535-9
  86. www.sciencedirect.com www.sciencedirect.com
    ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis
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  87. Dec 2022
  88. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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    embopress.org/doi/10.15252/embj.2022111961
  89. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Allicin ameliorates IMQ-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15983
  90. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    mdpi.com/2072-6643/14/24/5265
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vagus nerve stimulation is a potential treatment for ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC9700118/
  92. Nov 2022
  93. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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    embopress.org/doi/10.15252/embj.2022112006
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations
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